43,945 research outputs found
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
No full textThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of meson decays to J/ψη and J/ψη′
No full textFirst evidence of the B 0 → J / ψ ω decay is found and the B s 0 → J / ψ η and B s 0 → J / ψ η ′ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb -1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The branching fractions of these decays are measured relative to that of the B 0 → J / ψ ρ 0 decay:frac(B (B 0 → J / ψ ω), B (B 0 → J / ψ ρ 0)) = 0.89 ± 0.19 (stat) - 0.13 + 0.07 (syst),frac(B (B s 0 → J / ψ η), B (B 0 → J / ψ ρ 0)) = 14.0 ± 1.2 (stat) - 1.5 + 1.1 (syst) - 1.0 + 1.1 (frac(f d, f s)),frac(B (B s 0 → J / ψ η ′), B (B 0 → J / ψ ρ 0)) = 12.7 ± 1.1 (stat) - 1.3 + 0.5 (syst) - 0.9 + 1.0 (frac(f d, f s)), where the last uncertainty is due to the knowledge of f d / f s, the ratio of b-quark hadronization factors that accounts for the different production rate of B 0 and B s 0 mesons. The ratio of the branching fractions of B s 0 → J / ψ η ′ and B s 0 → J / ψ η decays is measured to befrac(B (B s 0 → J / ψ η ′), B (B s 0 → J / ψ η)) = 0.90 ± 0.09 (stat) - 0.02 + 0.06 (syst)
Laparoscopic versus open Burch colposuspension: a randomised controlled trial
No full textObjective To compare perioperative characteristics, short-term, and long-term outcomes for laparoscopic Burch colposuspension (LBC) and open Burch colposuspension (OBC) for the treatment of urinary stress incontinence
Developing partnership through Third Space activity
No full textThis paper reports on a small-scale research investigation into developing partnerships between a Higher Education Institution (HEI) in England and schools based on a collaborative, rather than a cooperative model. Here, a deeper’ interpretation of collaboration, that is to say ‘working together’ rather than ‘working with’ is facilitated through Third Space activity. In essence 'Third Space’ suggests coming out of our normal working environment at school or university) and into a neutral ‘third space’ to design, develop and deliver teacher education with jointly shared understanding and vision. The research was carried out during 2012 and consisted of non-participant observation of meetings between HEI and school staff involved in the partnership and semi-structure interviews with a sample of these staff. The university programme involved was the PGCE secondary programme, however it is important to note that the research suggested that the philosophy of Third Space activity to develop partnership transcends limitations of context. Findings suggest that, despite the ambitious nature of this philosophy, this kind of partnership working has the potential to be transformative for all concerned: HEI tutors, school mentors and student teachers. This in turn benefits pupils in school. As School Direct becomes more widespread in England, it is suggested that the benefits of this kind of working could add significantly to the evolution of effective partnership practice not only in the English context but also in teacher education world-wide
DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire
No full textThe majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire
J. T. Wiswall papers, W.0011
No full textAbstract: Two notebooks, containing mathematical equations and scientific essays, as well as the handwritten manuscripts of J. T. Wiswall's works "The African" and "Iliad of the Family," neither of which were ever published.Scope and Content Note: The collection contains two small, leather notebooks. One contains the handwritten manuscript "The African" and includes a bookplate identifying Caldwell Delaney as the owner. The other contains the handwritten manuscript "Iliad of the Family," as well as mathematical equations and scientific essays.Biographical/Historical Note: A Mobile, Alabama, author, J. T. Wiswall published two books,
The Last Crusader in 1861 and
Mr. Christopher Katydid (of Casconia) in 1864 (under the pseudonym Mark Heywood). The two handwritten manuscripts in this collection, "The African" and "Iliad of the Family," were never published, although they were listed in Robert E. Bell's
Bibliography of Mobile, which noted that Mobile historian Caldwell Delaney held the manuscripts in his private collection
Letter from J. R. Eakin to Carl Hayden
No full textLetter from J. R. Eakin to Carl T. Hayden concerning access to Rowe Well and the canyon
Letter from J. R. Eakin to Stephen Mather
No full textLetter from J. R. Eakin to Stephen T. Mather about expenses and reconstruction of the Kaibab Trail
Letter from Carl Hayden to J. B. Rickel
No full textLetter from Carl T. Hayden to J. B. Rickel concerning proposed changes to Grand Canyon National Park boundaries
Letter from Carl Hayden to P. J Moran
No full textLetter from Carl T. Hayden to P. J. Moran concerning the alignment of the road to Bright Angel Trail
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