468 research outputs found
Giving Miss Marple a makeover : graduate recruitment, systems failure and the Scottish voluntary sector
No full textThe voluntary sector in Scotland, as across the globe, is becoming increasingly business like. Resultantly, there is an increasing demand for graduates to work in business and support functions. In Scotland, however, despite an oversupply of graduates in the labor market, the voluntary sector reports skills shortages for graduate-level positions; a leadership deficit was also reported in countries such as the United States. Through exploratory, mainly qualitative, case study and stakeholder research, this article proposes that one reason for this mismatch between the supply of and demand for graduates is a systems failure within the sector. Many graduates and university students remain unaware of potentially suitable paid job opportunities, in part because of the sector's voluntary label. To rectify this systems failure, thought needs to be given to the sector's nomenclature and the manner in which voluntary sector organizations attract graduate recruits, for example, through levering value congruence in potential recruits
Measurement of the top-quark pole mass in dileptonic events at TeV with the ATLAS experiment
No full textA measurement of the top-quark pole mass is presented in ~events with an additional jet, , produced in collisions at TeV. The data sample, recorded with the ATLAS experiment during Run 2 of the LHC, corresponds to an integrated luminosity of 140 . Events with one electron and one muon of opposite electric charge in the final state are selected to measure the differential cross-section as a function of the inverse of the invariant mass of the system. Iterative Bayesian Unfolding is used to correct the data to enable comparison with fixed-order calculations at next-to-leading-order accuracy in the strong coupling. The process (), where top quarks are taken as stable particles, and the process (), which includes top-quark decays to the dilepton final state and off-shell effects, are considered. The top-quark mass is extracted using a fit of the unfolded normalized differential cross-section distribution. The results obtained with the and calculations are compatible within theoretical uncertainties, providing an important consistency check. The more precise determination is obtained for the measurement: GeV, which is in good agreement with other top-quark mass results.A measurement of the top-quark pole mass is presented in events with an additional jet, + 1-jet, produced in pp collisions at TeV. The data sample, recorded with the ATLAS experiment during Run 2 of the LHC, corresponds to an integrated luminosity of 140 fb. Events with one electron and one muon of opposite electric charge in the final state are selected to measure the + 1-jet differential cross-section as a function of the inverse of the invariant mass of the + 1-jet system. Iterative Bayesian Unfolding is used to correct the data to enable comparison with fixed-order calculations at next-to-leading-order accuracy in the strong coupling. The process , where top quarks are taken as stable particles, and the process , which includes top-quark decays to the dilepton final state and off-shell effects, are considered. The top-quark mass is extracted using a χ fit of the unfolded normalized differential cross-section distribution. The results obtained with the 2 → 3 and 2 → 7 calculations are compatible within theoretical uncertainties, providing an important consistency check. The more precise determination is obtained for the 2 → 3 measurement: GeV, which is in good agreement with other top-quark mass results.[graphic not available: see fulltext]A measurement of the top-quark pole mass is presented in events with an additional jet, , produced in collisions at TeV. The data sample, recorded with the ATLAS experiment during Run 2 of the LHC, corresponds to an integrated luminosity of . Events with one electron and one muon of opposite electric charge in the final state are selected to measure the differential cross-section as a function of the inverse of the invariant mass of the system. Iterative Bayesian Unfolding is used to correct the data to enable comparison with fixed-order calculations at next-to-leading-order accuracy in the strong coupling. The process (), where top quarks are taken as stable particles, and the process (), which includes top-quark decays to the dilepton final state and off-shell effects, are considered. The top-quark mass is extracted using a fit of the unfolded normalized differential cross-section distribution. The results obtained with the and calculations are compatible within theoretical uncertainties, providing an important consistency check. The more precise determination is obtained for the measurement: which is in good agreement with other top-quark mass results
Search for a CP-odd Higgs boson decaying into a heavy CP-even Higgs boson and a Z boson in the l+l-t(t)over-bar and ν(ν)over-barb(b)over-bar final states using 140 fb-1 of data collected with the ATLAS detector
No full textA search for a heavy CP-odd Higgs boson, A, decaying into a Z boson and a heavy CP-even Higgs boson, H, is presented. It uses the full LHC Run 2 dataset of pp collisions at s = 13 TeV collected with the ATLAS detector, corresponding to an integrated luminosity of 140 fb−1. The search for A → ZH is performed in the l+l−tt ̄ and νν ̄bb ̄ final states and surpasses the reach of previous searches in different final states in the region with mH > 350 GeV and mA > 800 GeV. No significant deviation from the Standard Model expectation is found. Upper limits are placed on the production cross-section times the decay branching ratios. Limits with less model dependence are also presented as functions of the reconstructed m(tt ̄) and m(bb ̄) distributions in the l+l−tt ̄ and νν ̄bb ̄ channels, respectively. In addition, the results are interpreted in the context of two-Higgs-doublet models
Measurement of t-channel single-top-quark production in pp collisions at s=5.02 TeV with the ATLAS detector
No full textThe observation of the electroweak production of single-top-quarks is made using 255 pb−1 of proton-proton collision data recorded at s=5.02 TeV with the ATLAS detector at the Large Hadron Collider. An event selection is used to identify single-top-quark candidates arising from t-channel production with the top quark decaying semi-leptonically. Events passing the selection are then used to measure the inclusive cross-section for the combined production of single-top-quarks and antiquarks, σ(tq+t ̄q), and the ratio Rt between these two. They are measured to be σ(tq+t ̄q)=27.1−4.1+4.4(stat.)−3.7+4.4(syst.) pb and Rt=2.73−0.82+1.43(stat.)−0.29+1.01(syst.). The individual single-top-quark (tq) and single-top-antiquark (t ̄q) production cross-sections are measured to be σ(tq)=19.8−3.1+3.9(stat.)−2.2+2.9(syst.) pb and σ(t ̄q)=7.3−2.1+3.2(stat.)−1.5+2.8(syst.) pb. All measurements are in good agreement with the Standard Model predictions
Int J Radiat Oncol Biol Phys
No full textPurpose:This study aims to combine multiparametric magnetic resonance imaging (MRI) and digitized pathology with machine learning to generate predictive maps of histologic features for prostate cancer localization.Methods and Materials:Thirty-nine patients underwent MRI prior to prostatectomy. After surgery, tissue was sliced according to MRI orientation using patient-specific 3-dimensionally printed slicing jigs. Whole-mount sections were annotated by our pathologist and digitally contoured to differentiate the lumen and epithelium. Slides were co-registered to the T2-weighted MRI scan. A learning curve was generated to determine the number of patients required for a stable machine-learning model. Patients were randomly stratified into 2 training sets and 1 test set. Two partial least-squares regression models were trained, each capable of predicting lumen and epithelium density. Predicted density values were calculated for each patient in the test dataset, mapped into the MRI space, and compared between regions confirmed as high-grade prostate cancer.Results:The learning-curve analysis showed that a stable fit was achieved with data from 10 patients. Maps indicated that regions of increased epithelium and decreased lumen density, generated from each independent model, corresponded with pathologist-annotated regions of high-grade cancer.Conclusions:We present a radio-pathomic approach to mapping prostate cancer. We find that the maps are useful for highlighting high-grade tumors. This technique may be relevant for dose-painting strategies in prostate radiation therapy. \ua9 2018 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).20182018-10-16T00:00:00ZR01 CA113580/CA/NCI NIH HHSUnited States/TL1 TR001437/TR/NCATS NIH HHSUnited States/U01 CE002944/CE/NCIPC CDC HHSUnited States/R01 CA218144/CA/NCI NIH HHSUnited States/UL1 TR001436/TR/NCATS NIH HHSUnited States/U01 NS088034/NS/NINDS NIH HHSUnited States/29908785PMC61905851167
Determination of visual detection thresholds of selected iron fortificants and formulation of iron-fortified pocket-type flat bread
No full textWheaten pocket-type flat breads were baked from refined flours fortified to contain iron from ferrous sulphate (FeSO4), hydrogen-reduced elemental iron (Fe) or sodium iron ethylenediaminetetraacetic acid (NaFeEDTA). Individual and group visual detection thresholds were determined by the 3-alternative forced choice (3-AFC) test according to the American Society of Testing and Materials (ASTM) method E-1432. The group visual detection thresholds of FeSO4, NaFeEDTA and Fe in bread were established in samples baked from the corresponding wheat flours fortified with 69.46, 236.82 and 304.97 mg iron-kg flour, respectively. Sensory testing showed that iron-fortified pocket-type flat breads were similar (P andlt; 0.01) to regular bread when baked from flours formulated to contain iron at levels lower by 25percent than the group visual detection thresholds of Fe and FeSO4 and two 25percent increments lower than the threshold of NaFeEDTA. These findings indicate that iron-fortified pocket-type flat breads, which are sensorially similar to regular bread, baked from flours that contained 52.1, 133.22 and 228.73 mg iron-kg flour as FeSO4, NaFeEDTA and Fe, would provide the segment of the population at the highest risk of iron-deficiency anaemia, specifically women of childbearing age, with 91percent, 207percent and 346percent of their recommended daily intakes for iron, respectively. © 2010 Elsevier Ltd. All rights reserved.Abebe Y, 2007, J FOOD COMPOS ANAL, V20, P161, DOI 10.1016-j.jfca.2006.09.003; Akhtar S, 2008, FOOD CHEM, V110, P113, DOI 10.1016-j.foodchem.2008.01.065; Alam S, 2007, INT J FOOD SCI NUTR, V58, P54, DOI 10.1080-09637480601121979; Allen L., 2006, GUID FOOD FORT MICR; Arredondo M, 2006, NUTR RES, V26, P235, DOI 10.1016-j.nutres.2006.05.009; ASTM, 1997, ANN BOOK ASTM STAND, P211; Bi J, 2005, FOOD QUAL PREFER, V16, P139, DOI 10.1016-j.foodqual.2004.03.003; Bovell-Benjamin AC, 2003, CRIT REV FOOD SCI, V43, P379, DOI 10.1080-10408690390826563; Emerton V, 2008, FOOD COLOURS; Hansen M, 2005, J CEREAL SCI, V42, P165, DOI 10.1016-j.jcs.2005.04.001; Hernandez M, 2003, J NUTR, V133, P154; Huma N, 2007, CRIT REV FOOD SCI, V47, P259, DOI 10.1080-10408390600698262; HURRELL RF, 2002, NUTR REV, V60, P7, DOI 10.1301-002966402320285137; Hurrell RF, 1997, NUTR REV, V55, P210; Hurrell RF, 2000, BRIT J NUTR, V84, P903; Institute of Medicine and Food and Nutrition Board, 2000, DIET REF INT VIT A V; Lawless H. T., 1998, SENSORY EVALUATION F; Le HT, 2007, FOOD QUAL PREFER, V18, P619, DOI 10.1016-j.foodqual.2006.09.001; Lim J, 2006, FOOD QUAL PREFER, V17, P513, DOI 10.1016-j.foodqual.2005.06.006; Martinez-Navarrete N, 2002, FOOD RES INT, V35, P225, DOI 10.1016-S0963-9969(01)00189-2; Meilgaard M.C., 2007, SENSORY EVALUATION T; Morales J, 2008, J FOOD SCI, V73, pS1, DOI 10.1111-j.1750-3841.2007.00581.x; Muwakkit S, 2008, J PEDIAT HEMATOL ONC, V30, P382, DOI 10.1097-MPH.0b013e318165b283; Rehman SU, 2006, J FOOD PROCESS PRES, V30, P323, DOI 10.1111-j.1745-4549.2006.00068.x; Richins AT, 2008, CEREAL CHEM, V85, P561, DOI 10.1094-CCHEM-85-4-0561; Sadighi J, 2008, PUBLIC HEALTH, V122, P313, DOI 10.1016-j.puhe.2007.05.002; Sun J, 2007, ASIA PAC J CLIN NUTR, V16, P116; Tazhibayev S, 2008, FOOD NUTR BULL, V29, P255; Tetens I, 2005, BRIT J NUTR, V94, P720, DOI 10.1079-BJN20051556; Toufeili I, 1999, J CEREAL SCI, V30, P255, DOI 10.1006-jcrs.1999.0286; van Stuijvenberg ME, 2008, J NUTR, V138, P782; Walter T, 2004, EUR J CLIN NUTR, V58, P555, DOI 10.1038-sj.ejcn.1601844; WHO, 2003, GEMS FOOD REG DIETS; *WHO, 2004, REG COMM E MED N AFR; *WHO UNICEF MI, 2003, JOINT WHO UNICEF MI; Ziadeh G, 2005, J FOOD SCI, V70, pS54811
Measurement of jet substructure in boosted events with the ATLAS detector using 140 fb of 13 TeV collisions
No full textMeasurements of the substructure of top-quark jets are presented, using 140 fb of 13 TeV collision data recorded with the ATLAS detector at the LHC. Top-quark jets reconstructed with the anti- algorithm with a radius parameter are selected in top-quark pair () events where one top quark decays semileptonically and the other hadronically, or where both top quarks decay hadronically. The top-quark jets are required to have transverse momentum GeV, yielding large samples of data events with jet values between 350 and 600 GeV. One- and two-dimensional differential cross-sections for eight substructure variables, defined using only the charged components of the jets, are measured in a particle-level phase space by correcting for the smearing and acceptance effects induced by the detector. The differential cross-sections are compared with the predictions of several Monte Carlo simulations in which top-quark pair-production quantum chromodynamic matrix-element calculations at next-to-leading-order precision in the strong coupling constant are passed to leading-order parton shower and hadronization generators. The Monte Carlo predictions for measures of the broadness, and also the two-body structure, of the top-quark jets are found to be in good agreement with the measurements, while variables sensitive to the three-body structure of the top-quark jets exhibit some tension with the measured distributions.Measurements of the substructure of top-quark jets are presented, using 140 fb-1 of 13 TeV pp collision data recorded with the ATLAS detector at the LHC. Top-quark jets reconstructed with the anti-kt algorithm with a radius parameter R=1.0 are selected in top-quark pair (tt¯) events where one top quark decays semileptonically and the other hadronically, or where both top quarks decay hadronically. The top-quark jets are required to have transverse momentum pT>350 GeV, yielding large samples of data events with jet pT values between 350 and 600 GeV. One- and two-dimensional differential cross sections for eight substructure variables, defined using only the charged components of the jets, are measured in a particle-level phase space by correcting for the smearing and acceptance effects induced by the detector. The differential cross sections are compared with the predictions of several Monte Carlo simulations in which top-quark pair-production quantum chromodynamic matrix-element calculations at next-to-leading-order precision in the strong coupling constant αS are passed to leading-order parton shower and hadronization generators. The Monte Carlo predictions for measures of the broadness, and also the two-body structure, of the top-quark jets are found to be in good agreement with the measurements, while variables sensitive to the three-body structure of the top-quark jets exhibit some tension with the measured distributions.Measurements of the substructure of top-quark jets are presented, using 140 fb of 13 TeV collision data recorded with the ATLAS detector at the LHC. Top-quark jets reconstructed with the anti- algorithm with a radius parameter are selected in top-quark pair () events where one top quark decays semileptonically and the other hadronically, or where both top quarks decay hadronically. The top-quark jets are required to have transverse momentum GeV, yielding large samples of data events with jet values between 350 and 600 GeV. One- and two-dimensional differential cross-sections for eight substructure variables, defined using only the charged components of the jets, are measured in a particle-level phase space by correcting for the smearing and acceptance effects induced by the detector. The differential cross-sections are compared with the predictions of several Monte Carlo simulations in which top-quark pair-production quantum chromodynamic matrix-element calculations at next-to-leading-order precision in the strong coupling constant are passed to leading-order parton shower and hadronization generators. The Monte Carlo predictions for measures of the broadness, and also the two-body structure, of the top-quark jets are found to be in good agreement with the measurements, while variables sensitive to the three-body structure of the top-quark jets exhibit some tension with the measured distributions
Screening forCronobacterSpecies in Powdered and Reconstituted Infant Formulas and from Equipment Used in Formula Preparation in Maternity Hospitals
No full textBackground/Aims: Cronobacter spp. have been identified as being of considerable risk to neonates. The occurrence of organism in infant formulas is therefore of considerable interest. Methods: The occurrence of Cronobacter spp. in infant feeds (formulas and fortified cow’s milk) was determined using most probable number (MPN) analysis, and from formula preparation utensils. Ninety nine samples were analyzed, of which 42 were unopened cans of powdered infant formula (PIF), 25 reconstituted infant formulas in feeding bottles, 27 utensils used from the preparation of infant formula, and 5 samples of fortified cow’s milk. Presumptive Cronobacter spp. isolates were identified using the 7 allele multilocus sequence typing (MLST) scheme. Results: C. sakazakii, C. malonaticus and C. muytjensii were recovered from PIF. Although the incidence of Cronobacter in PIF was 29% (12/42), the level was low with an average of 0.54 MPN/100g. According to MLST profiling, C. sakazakii was the most frequently isolated Cronobacter species, and C. sakazakii ST4 (associated with neonatal meningitis) was recovered from 2/42 PIF samples at 0.51 and 0.92 MPN/100g. Conclusions: Cronobacter spp. can be isolated from PIF and therefore strict hygienic practices during PIF preparation are important to minimize neonate exposure and reduce the risk of severe infections
Estimación Bayesiana de los parámetros estructurales de los modelos Multivariados Autoregresivos de Umbrales con ruido t-Student multivariado
No full textSometimes it is necessary to work with multivariate time series that have heavy tails and in particular multivariate Student t-noise. Unfortunately, there is no Bayesian methodology in the literature known to the author that allows estimating the structural parameters of a multivariate TAR model. In this sense, the analysis of the autoregressive multivariate models of thresholds and multivariate t-Student noise is carried out via the Bayesian approach and the proposed methodology is examined through simulations and an application in the stock market field.En algunas ocasiones es necesario trabajar con series de tiempo multivariadas que tienen colas pesadas y en particular ruido t-Student multivariado. Desafortunadamente no existe en la literatura, conocida por el autor, alguna metodología Bayesiana que permita estimar los parámetros estructurales de un modelo TAR multivariado. En ese sentido el análisis de los modelos multivariados autoregresivos de umbrales y ruido t-Student multivariado es llevado a cabo vía el enfoque Bayesiano y la metodología propuesta es examinada a través de simulaciones y una aplicación en el campo bursátil.Maestrí
Measurement of t-channel single-top-quark production in pp collisions at √s = 5.02 TeV with the ATLAS detector
No full textThe observation of the electroweak production of single-top-quarks is made using 255 pb−1 of proton-proton collision data recorded at √s = 5.02 TeV with the ATLAS detector at the Large Hadron Collider. An event selection is used to identify single-top-quark candidates arising from t-channel production with the top quark decaying semi-leptonically. Events passing the selection are then used to measure the inclusive cross-section for the combined production of single-top-quarks and antiquarks, σ(tq+t¯q), and the ratio Rt between these two. They are measured to be σ(tq+t¯q)=27.1−4.1+4.4(stat.)−3.7+4.4(syst.) pb and Rt=2.73−0.82+1.43(stat.)−0.29+1.01(syst.). The individual single-top-quark (tq) and single-top-antiquark (t¯q) production cross-sections are measured to be σ(tq)=19.8−3.1+3.9(stat.)−2.2+2.9(syst.) pb and σ(t¯q)=7.3−2.1+3.2(stat.)−1.5+2.8(syst.) pb. All measurements are in good agreement with the Standard Model predictions
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