1,720,969 research outputs found
Cost-Effectiveness of Oseltamivir and Favipiravir in Covid-19 Patients: a Cost-Effectiveness Analysis Study in a Hospital
Full text linkThe COVID-19 pandemic poses not only a threat to health but also to the global economy, including healthcare costs. Although there is no specific drug for COVID-19 patients, there are antiviral drugs such as oseltamivir and favipiravir that can be used to treat COVID-19. The purpose of this study was to determine the most cost-effective antiviral therapy between oseltamivir and favipiravir for COVID-19 patients in one of the hospitals in Banten province. The pharmacoeconomic method used in this study was cost-effectiveness analysis by calculating the Average Cost-Effectiveness Ratio (ACER) and Incremental Cost-Effectiveness Ratio (ICER). The results of this study showed that the ACER value of the favipiravir group (IDR 364,010 (n = 7)) was lower than the oseltamivir group (IDR 431,744 (n = 7)), with an ICER value of IDR 60,605. Based on the results of the Mann-Whitney test, there was no significant difference between the costs of the favipiravir and oseltamivir groups (p value 0.940). The sensitivity test showed that the cost of medical consumables was the cost that had the greatest impact on cost-effectiveness. Based on the calculation results, it can be concluded that the favipiravir group is more cost-effective than the oseltamivir group
UJI AKTIVITAS ANTIDIARE EKSTRAK ETANOL 70% KULIT BUAH JENGKOL (Archidendron pauciflorum (Benth.) I.C.Nielsen) TERHADAP MENCIT JANTAN YANG DIINDUKSI OLEUM RICINI
No full textCost effectiveness of cervical cancer prevention strategies in Indonesia
No full textBackground: The development of several HPV-related control techniques for the prevention of cervical cancer followed the identification of a link between high-risk human papillomavirus (HPV) infection and the occurrence of cervical cancer. Objective: The objective of the current study was to determine how cost-effective the different cervical cancer screening programs and HPV vaccinations in Indonesia. Methods: The lifetime costs and effects of vaccination among adolescent girls or screening with either the VIA, Papanicolaou, or HPV DNA test at various time intervals in a hypothetical cohort of 30-65 years-old women were estimated using a Markov model based on a societal perspective. Results: Based on statistics on transition probabilities, efficacy of HPV vaccination, and diagnostic accuracy of screening procedures. The findings of this study, specifically the cost-effectiveness of preventing cervical cancer with vaccination, revealed that each woman’s vaccination cost was 213, and the averted cost per death was 576 for years of quality-adjusted life saved and costs 1,532 for each preventable death. When the group of teenage girls who received the HPV, vaccine reaches the age of 30, the VIA screening frequency should be decided depending on the cohort’s overall HPV vaccination coverage
Aktivitas Ekstrak Daun Bangle (zingiber purpureum roxb.) Terhadap Pertumbuhan Bakteri Pseudomonas aeruginosa
Full text linkThe bacteria that cause infections that can lead to high morbidity and mortality, the bacterium Pseudomonas aeruginosa. Bangle has a pharmacological activity as antibacterial, laxative, pancreatic lipase inhibitor, and protect cells from damage caused by oxidative stress. The purpose of this study are: to know the chemical constituents present in the extract of leaves bangle (Zingiber purpureum Roxb.) Can be efficacious as an antibacterial and knowing Minimal Inhibitory concentration (MIC) of the extracts of leaves bangle against Pseudomonas aeruginosa. Tests on the leaf extracts for antibacterial activity against Pseudomonas aeruginosa bangle made by the method of Kirby Bauer and solvents used are DMSO. Test solution with a concentration of leaf extract bangle 200, 400, 600, 800 and 1,000 ppm, the positive control solution (ciprofoxacin) and the solution negative control (DMSO). The results showed that the chemical constituents present in the extract of leaves bangle (Zingiber purpureum Roxb.) Are flavonoids, saponins, tannins, alkaloids and steroids. Value Minimum Inhibitory Concentration (MIC) of ethanol extract of the leaf bangle S bacteria Pseudomonas aeruginosa is a concentration of 40 % with an average diameter of 5.44 mm inhibitory. MIC extract ethanol extract of leaf bangle belonging to the bacterial activity that is strong enough.
ANALISIS TERAPI ANEMIA PADA PASIEN GAGAL GINJAL KRONIK DI RSUD Dr. DRADJAT PRAWIRANEGARA TAHUN 2022
No full textAbstractUnder normal circumstances, 90% of the kidneys produce the hormone erythropoietin which has the function of stimulating the spinal cord to produce red blood cells, so that when kidney function decreases, there is a decrease in the production of the hormone erythropoietin which causes the formation of erythrocytes to be disrupted, resulting in a decrease in hemoglobin levels or anemia. The aim of this study was to determine the therapy of anemia in patients with chronic kidney failure undergoing hemodialysis and to determine the results of anemia therapy in patients with chronic renal failure undergoing hemodialysis at RSUD Dr. Dradjat Prawiranegara Year 2022. The research was conducted using a retrospective descriptive method by looking at the medical record data of chronic kidney failure patients undergoing hemodialysis who were receiving anemia therapy. The sample in this study amounted to 80 patients. The data were then analyzed descriptively regarding the analysis of anemia therapy in hemodialysis chronic kidney failure patients. The results showed that the hemodialysis hemoglobin level examination found an average of 8.8 g/dL and was included in the range below the normal value of hemoglobin levels. The most use of anemia drug therapy in 2022 for mono therapy is the most PRC Transfusion of 1 mg Folic Acid combination in 39 patients (48.8%). Furthermore, in the combination therapy of anemia with Blood Supplementary Tablets combined with Folic Acid 1 mg in 17 patients (21.3%) and the use of folic acid 1 mg in 24 patients (30.0%).Keywords: Anemia, Chronic Kidney Failure, Hemodialysis, RSUD Dr. Dradjat Prawiranegara
The Effect of Directly Observed Treatment Strategy on Cost Utility of Pulmonary Tuberculosis Patients at Banten Regional Public Hospital
No full textPulmonary tuberculosis (TB) is one of the communicable diseases with high prevalence in some provinces in Indonesia, including the Province of Banten. Considering its high prevalence and the high cost of treatment resulting from multiple treatment components, research on the analysis of treatment costs of TB is very important. This study aimed to determine the effect of implementing the directly observed treatment (DOT) strategy on the cost-utility of pulmonary TB patients. The study was conducted at Banten Regional General Hospital using the perspective of the health provider and patients by involving 24 TB patients. Treatment cost was calculated by including direct medical costs, direct non-medical costs, and indirect costs, and then categorized into initial and final cost-utility. The average cost-effectiveness ratio (ACER) was then calculated by setting the patient's quality of life as the clinical outcome in this study. This study found that the average value of the average cost-utility ratio (ACUR) for the initial cost-utility and the final cost-utility were IDR 2,682,343.53 and IDR 2,402,153.15, respectively, and the difference was statistically significant (p=0.006). It indicates that the DOT strategy can potentially improve the utility costs of the treatment of TB patients at Banten Regional Hospital
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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