6 research outputs found

    Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor β (TR-β) selective ligands

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    Design and synthesis of a novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives are reported and their in vitro thyroid hormone receptor selectivity has been evaluated in the thyroid luciferase receptor assay. The 3-[3,5-dichloro-4-(4-hydroxy-3-isopropylphenoxy)-phenylamino]-4-hydroxy-cyclobut-3-ene-1,2-dione 21 has shown selectivity towards thyroid hormone receptor β

    Understanding, assessing, comparing, and managing risks related to the energy transition from fossil fuel to renewables – for Norway and India

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    There is growing worry about the future supply of fossil-fuel-based energy and its environmental consequences. There is call for the globe to switch from fossil fuels to renewable energy sources. (Teles et al., 2015). On the other hand, the speed and scale of this shift remain uncertain and arguable. (Gribkova & Milshina, 2022). The energy transition is inherently risky. (Poudineh et al., 2019). The main objectives of the thesis are to gain improved knowledge of the risks related to the energy transition from fossil fuel to renewables for Norway and India, and contribute to improve the assessment and management of these risks. The energy industry is responsible for nearly three-quarters of the emissions that have already increased world average temperatures by 1.1 degrees Celsius since pre-industrial times, with evident effects on weather and climate extremes. The energy industry must be at the center of the climate change solution. (IEA, 2021b). The thesis performs risk analysis for both nations using Bayesian network, compares and demonstrates the variations in the study's outcomes, as well as the different risk management approaches that they may use. The Bayesian network events and consequences are interlinked, and the sequence of action may or may not be followed as demonstrated as it depends on the various factors and the probability of occurrences of scenarios involving these factors. Factors such as government policies encouraging renewable energy and energy efficiency, technology and innovation, people expectations, Covid-19 will all play a role in the sequence. The thesis further shows that socioeconomic factors influence the risks and the energy transition for both the countries. Risk comparison demonstrates that a same risk problem in two distinct situations (here, two separate nations) is not identical. The risk comparison underlines the importance of conducting a context assessment first in order to have a better understanding of risk. Risk management strategies are suggested in this thesis for the management of risks for Norway and India which contributes to improved risk management of the energy transition risks for Norway and India. Risk informed strategy is used in the thesis wherein risk treatment methods are suggested for the identified risk sources and initiating events. When one wants to choose between several solution alternatives for the energy transition problem then the author suggests that a multi-attribute analysis is a better approach for decision making because there are several factors influencing the decision-making process, including energy sources, energy demands, population, economy, geography, political goals and strategies, ethical factors, social factors, personal factors, infrastructure needs, citizen psychology, societal preference, speed of transition, and in general its magnitude. The author believes that the governments must try to strike a balance between the various attributes. These questions have no definitive solutions. The author of this thesis emphasizes that whether precautionary principle be given more or less weight is the choice of the decision maker. Companies should propose alternative uses of oil and gas utilities to successfully tackle the energy transition barrier and enhance the degree of risk acceptability and tolerance in the energy market. For productive operations, organizations should take effective precautions and adopt contemporary risk acceptability models such as ALARP. By performing risk analysis and comparing the risks these countries face in achieving the Paris Climate Agreement and the Sustainable Development Goals using various risk management strategies, this thesis contributes to a better understanding of the energy transition risks and improved risk assessment & risk management for Norway and India

    Nanoelectromechanical resonators from high-T <sub>c</sub> superconducting crystals of Bi <sub>2</sub> Sr <sub>2</sub> Ca <sub>1</sub> Cu <sub>2</sub> O&lt;IMG ALIGN=MIDDLE ALT=-8+δ

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    In this report, we present nanoelectromechanical resonators fabricated with thin exfoliated crystals of a high-T c cuprate superconductor Bi 2 Sr 2 Ca 1 Cu 2 O. The mechanical readout is performed by capacitively coupling their motion to a coplanar waveguide microwave cavity fabricated with a superconducting alloy of molybdenum-rhenium. We demonstrate mechanical frequency tunability with external dc-bias voltage, and quality factors up to ∼36 600. Our spectroscopic and time-domain measurements show that mechanical dissipation in these systems is limited by the contact resistance arising from resistive outer layers. The temperature dependence of dissipation indicates the presence of tunneling states, further suggesting that their intrinsic performance could be as good as other two-dimensional atomic crystals such as graphene. Accepted Author ManuscriptQN/Steele La

    Scientometric Analysis of Quarterly E-journals of Health Science

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    The main objective of the study is to find out most prolific authors and journals in the health medicine research output during 2001 to 2013. A total of 20724 research papers were examined by growth of contribution by year and volume, authorship pattern. Highest number of contribution i.e. 2335 (11.27%) were published in the year 2011. Issue Number 4 published articles in the maximum 1907 (09.20%) articles, Multi-authored highest articles, Findings of the analysis revealed that the majority of the publications are contributed by multiple author, Highest number of papers was published by more than three authors and it accounts for 9472 with 45.71%; the most language used for communication was English, Journal of Internal Medicine had contributed maximum number of citations

    Penciptaan Seni Lukis Ilusi Tiga Dimensi

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    Seni lukis Ilusi tiga dimensi adalah seni lukis berupa dua dimensi tetapi bentuk visualnya mempunyai pencitraan seolah-olah tiga dimensi.nbsp; Penciptaan seni lukis ilusi tiga dimensi didasari oleh hasil eksplorasi penulis tentang pencapaian teknik yang dipelajari penulis selama berkesenian. Dan didukung oleh pengalaman pembuatan karya mural di berbagai tempat yang diyakini penulis sebagai proses perjalanan berkarya. Pembuatan seni lukis ilusi tiga dimensi diterapkan pada media kerei bambu yang dirasa penulis sebagai media unik yang mempunyai tingkat kesulitannya sendiri dalam proses pembuatan karya. selain itu tembok jurusan seni rupa dipilih sebagai pengganti kanvas. Tembok kampus dipilih karena penulis ingin berbagi dengan penghuni kampus untuk ikut merasakan proses pembuatan karya ilusi tiga dimensi. Karya yang dihasilkan penulis ada 3 seri, 1 karya di media bambu dan dua karya di media tembok. Seri 1 di kerei bambu mengusung tema tentang perlindungan hiu yang didapatkan dari isu sosial media saat itu. Karya kedua dengan media tembok di jurusan menggusung tema tentang proses perjalanan belajar menggambar di jurusan seni rupa Unesa. Karya ketiga berada di tembok ruang meeting jurusan seni rupa yang mengambil tema gaya seni rupa modern kemudian digambar ulang dengan gaya Ilusi tiga dimensi. nbsp; nbsp;nbsp; 3D-illusion art painting is exactly 2D painting with eye trick imaging looking like 3D. Creation of 3D-painting art based on the author exploration result of his achivements on the techniques learn by him so far in arts. Supported by his experience in making mural paintings in many places, the artist believes it as the process of his art journey.Making of 3D-illusion art is applied by the author on media if bamboo blinds that are considered as a unique media with certain difficulties in the process of making them. Besides, the wall of art faculty in his campus are chosen to be the canvas. The wall-canvas is the means for the authornbsp; to share his feeling of the process in making his art work of 3D-illusion paintings.Art work has produced by the author there are three series. The first art work in on bamboo,and another two are on the wall. The first art work on bamboo layer is carrying intent about the problem of save sharks that being headline on social media. The second art work is on art majors wall carrying intent about the process of learn to draw in the university of surabaya (Unesa). The third art work is on the art majors meeting room wall and carrying intent about modernism art then repainted being 3D illusion style

    Fire in the dark : telling gypsiness in North East England

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