8 research outputs found
PENGARUH PEMBERIAN SARI BONGGOL NANAS (Ananas comosus) KONSENTRASI 1%, 3% dan 5% TERHADAP PENYEMBUHAN ULKUS TRAUMATIKUS PADA MALE WISTAR RATS DILIHAT DARI KEPADATAN SERABUT KOLAGEN - Penelitian Eksperimental Laboratoris (In vivo)
No full textUlkustraumatikus merupakan salah satu jenis ulkus yang paling sering terjadi di rongga mulut, penyebabnya adalah trauma. Ulkus biasanya menimbulkan nyeri, sehingga harus segera diobati. Obat yang sering dipakai adalah topikal kortikosteroid Kenalog in Orabase®, namun obat ini dapat menimbulkan efek imunosupresan. Nanas merupakan salah satu tanaman yang berkhasiatobat yang dapat membantu penyembuhan luka, salah satu kandungannya adalah enzim bromelin yang banyak ditemukan di bonggolnya. Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian sari bonggol nanas terhadap penyembuhan ulkus traumatikus pada tikus galur wistar dilihat dari kepadatan serabut kolagen.
Penelitian eksperimental in vivo dengan rancangan post-test only design dilakukan pada 30 ekor tikus galur wistar jantan yang dibagi menjadi 5 kelompok: aquadest, Kenalog in Orabase®, sari bonggol nanas 1%, sari bonggol nanas 3%, sari bonggol nanas 5%. Penyembuhan ulkus dilihat dari kepadatan serabut kolagendan data dianalisa dengan One-way Anova dilanjut Post-hoc LSD.
Hasil penelitian menunjukkan kepadatan kolagen pada kelompok aquadest (7.32%), Kenalog in Orabase®(9.93%), sari bonggol nanas 1%(11.38%), sari bonggol nanas 3% (14.86%), sari bonggol nanas 5% (17.97%). HasilujiOne-way Anovap=0.00, yang artinya terdapat pengaruh pemberian sari bonggol nanas konsentrasi 1%, 3% dan 5% terhadap penyembuhan ulkus traumatikus. Hasil uji Post-hoc LSD menunjukkan terdapat perbedaan rerata kepadatan kolagen yang bermakna (p<0.05) antar kelompok penelitian.
Dari hasil penelitian dapat disimpulkan bahwa terdapat pengaruh pemberian sari bonggol nanas terhadap proses penyembuhan ulkus traumatikus dilihat dari kepadatan serabut kolagen.
Kata kunci : Bonggol nanas, Ulkustraumatikus, Penyembuhan Luka, Kolage
Frenectomy Using Z-Plasty Technique in Case of Aberrant Frenum on Aesthetic Zone
No full textBackground: Aberrant frenum can cause many problems such as central diastema, food impaction, dental caries, and aesthetic problems. This case can be handled with frenectomy, which is Z-Plasty technique can be used to treat thick and wide frenulum associated with papillary penetrate and central diastema. Case Report: A 17 years old girl was referred from orthodontist to Department of Periodontics, RSGM UGM Prof. Soedomo Yogyakarta for treatment of maxillary labial frenulum. Intra-oral examination revealed a diastema on the maxillary central incisor of 2.5 mm and frenulum attachment extended to the palatine papilla. In this case, collaborative perio-ortho treatment was carried out, frenectomy with Z-Plasty technique done to correct thick frenulum and fixed orthodontic treatment to correct central diastema after completion of periodontal treatment. Evaluations are carried out every 7 days for the first 2 weeks then at 3 and 6 months after periodontal procedure. Conclusion: Frenectomy using Z-Plasty technique was able to correct wide and thick frenulum that extends to the palatine papilla. Good wound healing, minimal scarring and color matching the surrounding tissue, and perio-ortho collaboration treatment was successfully carried out with satisfactory results according to the patient's wishes
Osteocalcin levels in gingival crevicular fluid periodontitis patient with and without type 2 Diabetes Mellitus
No full textBackground: Diabetes Mellitus (DM) is a systemic disease with a high prevalence in Indonesia. Periodontitis is a complication of DM with frequent occurrences. Periodontitis with DM causes greater bone damage than non-DM periodontitis because its conditions can affect osteoblast and osteoclast activity. Osteocalcin (OC), mostly synthesized by osteoblasts, regulates the activity of bone formation and turnover so that it can be a marker of bone formation and turnover to see the severity of the disease. OC can be found in gingival crevicular fluid (GCF). This study aimed to determine osteocalcin levels in gingival crevicular fluid periodontitis patients with uncontrolled type 2 Diabetes Mellitus and non-Diabetes Mellitus.Method: Samples used in this study were gingival crevicular fluid taken from 20 samples of periodontitis patients with DM type 2 (DMT2P) and 20 samples of periodontitis non-DM patients. The OC levels were analyzed using ELISA Kit Osteocalcin then statistical tests were carried out.Result: The results showed that the OC level of the DMT2P group was 0.369 ± 0.140 while the periodontitis non-DM group was 0.664 ± 0.141.Conclusion: The OC levels of periodontitis patients with DM are lower than periodontitis patients non-DM
ادب کی تفہیم: ردِتشکیل کے تناظر میں
No full textUnderstanding literature relates to the interpretation of a literary text in a specific perspective. The critical appreciation, analysis and establishing an opinion about the text are some of the important tools to understand a literary piece of work. For this purpose, a complete understanding of literary as well as critical theory is indispensible to move forward. There are various perspectives to understand literature, which may be divided into four major categories; these are Author oriented, Context oriented, Reader oriented and Text oriented. This paper presents the debates of understanding literature in the context of Deconstruction; a theory presented by Jacques Derrida. The main idea of this theory is to unveil those meanings of the text, which have not been revealed on the surface. A limited work is available in the field of Urdu Applied Criticism with special reference to Deconstruction; because this analytical approach has been ignored. This theory may be applied to understand literature with the help of discourse analysis, narratology, linguistic analysis and textual criticism.
Blockchain and Internet of Things in smart cities and drug supply management: Open issues, opportunities, and future directions
No full textBlockchain-based drug supply management (DSM) requires powerful security and privacy procedures for high-level authentication, interoperability, and medical record sharing. Researchers have shown a surprising interest in Internet of Things (IoT)-based smart cities in recent years. By providing a variety of intelligent applications, such as intelligent transportation, industry 4.0, and smart financing, smart cities (SC) can improve the quality of life for their residents. Blockchain technology (BCT) can allow SC to offer a higher standard of security by keeping track of transactions in an immutable, secure, decentralized, and transparent distributed ledger. The goal of this study is to systematically explore the current state of research surrounding cutting-edge technologies, particularly the deployment of BCT and the IoT in DSM and SC. In this study, the defined keywords “blockchain”, “IoT”, drug supply management”, “healthcare”, and “smart cities” as well as their variations were used to conduct a systematic search of all relevant research articles that were collected from several databases such as Science Direct, JStor, Taylor & Francis, Sage, Emerald insight, IEEE, INFORMS, MDPI, ACM, Web of Science, and Google Scholar. The final collection of papers on the use of BCT and IoT in DSM and SC is organized into three categories. The first category contains articles about the development and design of DSM and SC applications that incorporate BCT and IoT, such as new architecture, system designs, frameworks, models, and algorithms. Studies that investigated the use of BCT and IoT in the DSM and SC make up the second category of research. The third category is comprised of review articles regarding the incorporation of BCT and IoT into DSM and SC-based applications. Furthermore, this paper identifies various motives for using BCT and IoT in DSM and SC, as well as open problems and makes recommendations. The current study contributes to the existing body of knowledge by offering a complete review of potential alternatives and finding areas where further research is needed. As a consequence of this, researchers are presented with intriguing potential to further create decentralized DSM and SC apps as a result of a comprehensive discussion of the relevance of BCT and its implementation.© 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).fi=vertaisarvioitu|en=peerReviewed
Hypertrophic cardiomyopathy is associated with dilated sinus of Valsalva: A case-control study
No full textBackground: We aimed to test the hypothesis that there is an association between hypertrophic cardiomyopathy and dilated aorta in a case-control, matched-design fashion. Methods: Of 65,843 studies done from November 2011 to December 2015, we found, after detailed evaluation by a single author, 153 cases of hypertrophic cardiomyopathy and 3,213 controls who were classified as normal clinically and echocardiographically. Controls were defined as normal patients referred to the echocardiography laboratory with no diagnoses and no known risk factors for dilated aorta (e.g., aortic stenosis, hypertension, aortic regurgitation). Clinical chart review showed none of the risk factors for dilated aorta, and echocardiography did not reveal any abnormalities. Of these 3,213 patients, 153 controls were matched to cases by age and sex by propensity score. Dilated aorta was defined according to clinical, Goldstein, and Lang's criteria. Results: The prevalence of a dilated sinus of Valsalva was 9 times higher in hypertrophic cardiomyopathy patients than controls (OR = 9.4, P = 0.003). The 9-fold higher prevalence in hypertrophic cardiomyopathy patients persisted after adjusting for height, weight, and aortic pathology. Association of dilated mid-ascending aorta with hypertrophic cardiomyopathy was significant after adjustment for height and body surface area but became borderline insignificant after adjusting for weight and aortic valve pathology. Conclusion: Hypertrophic cardiomyopathy appears to be associated with a dilated sinus of Valsalva, even after adjusting for height, weight, and aortic valve pathology
Salutogenesis: A sense of coherence and health among British military veterans exposed to impactful life challenges - the emergence of post-traumatic growth and positive deviance within a life-story approach [version 1; peer review: 3 approved]
No full textBackground This study sought to capture the perspectives and experiences of two sub-groups of military veterans, namely those who had previously been identified as offenders and those employed as practitioners within the criminal justice system in the United Kingdom. Methods The lead author undertook narrative inquiry in the form of life story research. The life stories of 17 in-depth interviews were conducted across England and Wales, allowing for insight into the lived experiences of two life story trajectories of the health of military veterans. Existing literature on salutogenesis, health, post-traumatic growth, and positive deviance has also been investigated. Results Life story interviews were transcribed verbatim and analyzed concurrently using thematic analysis to identify emergent themes. The researchers used thematic analysis as an analytical framework to allow descriptive themes from the literature on salutogenesis, health, post-traumatic, and positive deviance to be compared with those of life-story interviews. Conclusion The study adopts a salutogenic approach, which suggests that an important indicator for a sense of coherence is enabled through the positive utilization of resilience through the reconstruction of military identity and experience. Notably, the concept of salutogenesis demonstrates the ability to draw from internal and external resources as circumstances require, to survive, and because of this, the participants’ health is maintained or improved. Hence, adaptation was notable through the coherence identified by the identity of being a veteran noted between the two subgroups and represents a continuous and dynamic process. The study suggests that the development of a sense of coherence is not restricted to the early decades of life but is a continuous process as contexts, personal circumstances, and opportunities arise. This later point is realized through the presence of post-traumatic growth and positive deviance, as they aid in the nurturing and development of a renewed sense of coherence via the known identity of military service and life
Citizenship and political participation in the State of Kuwait : the case of National Assembly (1963-1996)
No full textEThOS - Electronic Theses Online ServiceGBUnited Kingdo
