309 research outputs found

    Cours alphabétique et méthodique de droit canon : dans ses rapports avec le droit civil ecclésiastique ...

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    Datos del impresor: No v. da antep. do v. II e III consta: "Imprimé par Charles Noblet" e no colofón: "París : typ. Ve. Lacour". As ´duas imprentas teñen o mesmo enderez

    Teoría y construccion de los cañones rayados

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    El pie de imp del t. II : Madrid: imprenta y librería de Eusebio AguadoT.I: 205, [1] p., [4] h. de grab. pleg.; T.II: 141, [3] p., V-VIII h. de grab. plegLas h. de lám. pleg.: "Etablt. et imprie. de Noblet et Baudry

    Corrigendum to “What do vegetable farmers expect from climate services to adapt to climate change by 2060? A case study from the Parisian region” [Clim. Serv. 34 (2024) 100474]

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    International audienceThe authors regret to inform that in the published version of the manuscript there were errors in the authorship details that require correction. The correct author order and spelling corrections are updated as above.The revised Authorship statement is as follows:Nabil Touili: Writing – review & editing, Writing – original draft, Validation, Methodology, Formal analysis. Christine Aubry: Visualization, Supervision, Project administration. Nathalie de Noblet-Ducoudré: Methodology, Writing – review & editing, Validation. Kevin Morel: Writing – review & editing, Validation, Methodology, Formal analysis, Supervision.Please note that these corrections do not affect the scientific content of the manuscript.The authors would like to apologize for any inconvenience caused

    A practice based learning environment for engineering students: Acquiring competencies for working on advanced manufacturing engineering

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    This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In this thesis the author describes the design and operation of a learning environment aimed at imparting technical, technological and managerial knowledge, developing understanding of the underlying issues and enhancing team work skills for an advanced technology future. He offers an analysis of learning, education and training and compares group work with individual tasks, presents a major case study and illustrates the features which distinguish the approach from role play, simulation and experiential learning. When staff at Brunel University were faced with the problem of teaching Computer Integrated Manufacturing (CIM) to engineering students on thin sandwich type undergraduate degree programmes the writer suggested the use of an approach he would later describe as 'practice based learning' or 'real life simulation'. The fourth year course in CIM is designed as a double option for the complementary undergraduate courses, Brunel Manufacturing Engineering (BME) and Special Engineering Programmes (SEP). It is an extension of the Manufacturing Design and Practice course in years one to three of the BME course and of the Design strand on SEP, both of which restrict students' work to the use of individual machine tools and stand alone computing facilities. A wide range of teaching methods is used on the CIM course, including lectures by course staff, presentations by experts and, as the major element, a large group project involving all the students on the course, organised in a management matrix, coordinated by the students and supported by the staff acting as experts. The students also undertake assignment work alongside the technical tasks, to focus their thinking and to improve written communication skills. While the course described cannot replace more than a small proportion of the more conventional lecture, laboratory and tutorial teaching on an engineering programme, it provides a setting where students can experiment and learn about their own strengths and weaknesses in a realistic situation and in the context of teamwork. It also offers a space where they can make quite serious mistakes without direct consequences to their careers. The experience of seven years leads the author to believe that advanced manufacturing technologies and the associated management techniques should be taught in a project based environment with clear and real targets and realistic constraints, offering students challenges to which they can only rise through close and creative team work. The management of task execution must be left largely in the students' own hands. A high level of "consultant" type support is essential though, allied to an assessment scheme which promises and ensures fair treatment of the individual. The different parts of the thesis will be relevant to readers depending on their interest and background. Chapter 1 sets the scene and outlines the approach taken. Following this broad outline of the scope of the dissertation the author places Computer Integrated Manufacturing in a wider context in chapter 2, by providing an introduction to the underlying issues of computer integration and human factors. He puts forward a case for new approaches to the education and training of engineers and managers who will be working in Computer Integrated Manufacturing and Advanced Manufacturing Environments in general. Chapter 3 is devoted to the management of projects while chapter 4 is used to question the role of the engineer. Chapters 5 and 6 provide an introduction to theories of knowledge, teaching, learning and motivation. Chapters 7 and 8 are devoted to particular aspects of engineering education, while chapter 9 reviews the approach used at Brunel University. The topical issues of competence and its relevance to engineering education is discussed in chapter 10, leading into chapters 11 and 12 which deal with aspects of the CIM course. Chapters 13 and 14 are devoted to case-studies and particular tools. The key question of assessment of a practice oriented and team based course is addressed in chapter 15, followed by an evaluation of the CIM process and its application to engineering education of a full time nature which is included in chapters 17 and 18.Funding was obtained from The General Electric Company Prize 1993: Manufacturing Systems Engineering

    Fonds Weissenbruch (Farde 34)

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    Pièce 1 -- Quittance d'abonnement au Journal encyclopédique signée Gonu de Champigny, Paris, 22 décembre 1786. 1 feuillet. Document imprimé. Pièce 2 -- Quittance d'abonnement au Journal politique signée le Marquis de Noblet D'Auglure, Paris, 8 janvier 1789. 1 feuillet. Document imprimé. Pièce 3 -- Lettre de Dame Valade-Despilly à Charles de Weissenbruch, Nantes, 20 mars 1790. 1 feuillet. Pièce supplémentaire 1 -- Lettre de Ducellier à Charles de Weissenbruch et Pierre Rousseau concernant un renouvellement d'abonnement au journal, Erloy, 5me jour complémentaire an V [21 septembre 1797]. 1 feuillet

    Premières Danseuses and their admirers - the green room of the Opera House (King's Theatre) 1822

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    Bildunterschrift: „PREMIÈRES DANSEUSES AND THEIR ADMIRERS_THE GREEN ROOM OF THE OPERA HOUSE (KINGS THEATRE) 1822.", "EARL OF FIFE. BALL HUGHES. MDLLE. MERCANDOTTI. MDLLE. NOBLET. PRINCE V. ESTERHAZY. MDLLE. HULLIN. LORD PETERSHAM.“.Bleistiftvermerk auf der Rückseite von Friderica Derra de Moroda: „I gave Isabel she gave it back 1959“

    Does interventional MRI-guided brain cryotherapy cause a blood–brain barrier disruption? Radiological analysis and perspectives

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    Glioblastoma is the most common primary malignant brain tumor with an incidence of 5/100,000 inhabitants/year and a 5-year survival rate of 6.8%. Despite recent advances in the molecular biology understanding of glioblastoma, CNS chemotherapy remains challenging because of the impermeable blood–brain barrier (BBB). Interventional MRI-guided brain cryotherapy (IMRgC) is technique that creates a tissue lesion by making a severe targeted hypothermia and possibly a BBB disruption. This study goal was to analyze the effect of IMRgC on human BBB glioblastoma through its gadolinium enhancing features. All patients harboring a local glioblastoma recurrence and meeting all the inclusion criteria were consecutively included into this retrospective study during a 2-year period. The primary endpoint was to analyze the modification of the gadolinium enhancement on MRI T1 sequences using MR perfusion weighted images during follow-up. The secondary endpoint was to assess any ischemic/hemorrhagic complication following cryotherapy procedure using diffusion weighted imaging (DWI), susceptibility weighted imaging (SWI), or fluid-attenuated inversion recovery (FLAIR). Among the 6 patients studied, all (100%) showed a BBB disruption on the cryotherapy site through the analysis of the perfusion weighted images with an average delay of 2.83 months following the procedure. The gadolinium enhancement located around the cavity then spontaneously decreased in 4/6 patients (67%). No ischemic or hemorrhagic complication was recorded. This study confirms the IMRgC capacity to disrupt BBB as already suggested by the literature. IMRgC might represent a new option in the management of GBM allowing the combined effect of direct cryoablation and enhanced chemotherapy

    Premières Danseuses and their admirers - the green room of the Opera House (King's Theatre) 1822

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    Bildunterschrift: „PREMIÈRES DANSEUSES AND THEIR ADMIRERS_THE GREEN ROOM OF THE OPERA HOUSE (KINGS THEATRE) 1822.", "EARL OF FIFE. BALL HUGHES. MDLLE. MERCANDOTTI. MDLLE. NOBLET. PRINCE V. ESTERHAZY. MDLLE. HULLIN. LORD PETERSHAM.“.Bleistiftvermerk auf der Rückseite von Friderica Derra de Moroda: „I gave Isabel she gave it back 1959“
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