714 research outputs found
Container ports in developing countries: barriers to participation in the global economy
No full textThis dissertation investigates whether organizational and technological changes in the global economy, the port and maritime industry, and infrastructure financing have created port development barriers for developing countries on the global periphery. The restructuring of the international economy and development of global supply chains has altered both the routes and manner in which goods are traded. The port infrastructure that connects economies to the system of global trade has changed significantly in response to containerization of manufactured trade. The financing of port development has also evolved as governments have transferred investment responsibilities to the private sector. This dissertation proposes that changes in the global economy, maritime industry, and port financing models have created barriers to port development for countries on the global periphery. Port development barriers can have a significant impact on these countries’ economic development. This research examines potential solutions for overcoming port development barriers, and also discusses some future trends that may shape the port development patterns and the overall global economy in the future.Ph.D.Includes bibliographical references (p. 158-161)by William Tricot Laventha
Blood stem cell collections after mobilization with combination chemotherapy containing ifosfamide followed by G-CSF in multiple myeloma
Get PDFHigh-dose chemotherapy with autologous peripheral blood stem cell transplantation is the standard treatment of patients with multiple myeloma today. In this study we used a combination mobilizing chemotherapy containing ifosfamide with G-CSF before stem cell collection. The chemotherapy regimen consisted of ifosfamide (2,500 mg/m(2) days 1-3), epirubicin (100 mg/m(2) day 1) and etoposide (150 mg/m2 days 1-3) followed by G-CSF (5 mug/kg from day 5). In 30 younger patients (median age 51 years; range 41-60 years) who received the IEV regimen in 100% dosage, a median of 11.15 x 10(6) CD34(+) cells/kg (range 0-44.60 x 10(6) CD34(+) cells/kg) was collected. In 22 elder patients (median age 64 years; range 59-72 years) similar collection results were obtained with a median of 10.82 x 10(6) CD34(+) cells/kg (range 0.99-42.22 x 10(6) CD34(+) cells/kg) after the IEV regimen in 75% dosage. The pretreatment chemotherapy cycles before mobilization were fewer in elder patients with a median of 0 cycles (range 0-7 cycles) compared with younger patients with a median of 4 cycles (range 0-7 cycles). These collection results were favorable and allowed to support a tandem transplantation procedure in younger and elder patients in 97 and 95%, respectively. In the majority of patients, the hematological toxicity of IEV was of WHO grade 3/4. The extramedullary toxicity was mild to moderate and there were only few cases (5-10%) of relevant nephrotoxicity or neurotoxicity associated with the application of ifosfamide. Copyright (C) 2003 S. Karger AG, Basel
On the Mechanisms of the Kinitting Method of the Tricot Machine(II)
Get PDFThe cams which is used in the knitting parts of the tricot machine is a complex type having two definite functions brought about by the front and back rollers which follow the two faces of the composit cam. The first function is to lead the thread and the second is to prevent the vibration. The author analysing thus elucidated in the present paper the cause of the vibration finding the value of Coriolis' functional acceleration equation.departmental bulletin pape
On the Mechanisms of the Kinitting Method of the Tricot Machine(II)
No full textThe cams which is used in the knitting parts of the tricot machine is a complex type
having two definite functions brought about by the front and back rollers which follow the
two faces of the composit cam. The first function is to lead the thread and the second is
to prevent the vibration.
The author analysing thus elucidated in the present paper the cause of the vibration
finding the value of Coriolis' functional acceleration equation
The tricot approach: an agile framework for decentralized on-farm testing supported by citizen science. A retrospective
No full textMatching crop varieties to their target use context and user preferences is a challenge faced by many plant breeding programs serving smallholder agriculture. Numerous participatory approaches proposed by CGIAR and other research teams over the last four decades have attempted to capture farmers’ priorities/preferences and crop variety field performance in representative growing environments through experimental trials with higher external validity. Yet none have overcome the challenges of scalability, data validity and reliability, and difficulties in capturing socio-economic and environmental heterogeneity. Building on the strengths of these attempts, we developed a new data-generation approach, called triadic comparison of technology options (tricot). Tricot is a decentralized experimental approach supported by crowdsourced citizen science. In this article, we review the development, validation, and evolution of the tricot approach, through our own research results and reviewing the literature in which tricot approaches have been successfully applied. The first results indicated that tricot-aggregated farmer-led assessments contained information with adequate validity and that reliability could be achieved with a large sample. Costs were lower than current participatory approaches. Scaling the tricot approach into a large on-farm testing network successfully registered specific climatic effects of crop variety performance in representative growing environments. Tricot’s recent application in plant breeding networks in relation to decision-making has (i) advanced plant breeding lines recognizing socio-economic heterogeneity, and (ii) identified consumers’ preferences and market demands, generating alternative breeding design priorities. We review lessons learned from tricot applications that have enabled a large scaling effort, which should lead to stronger decision-making in crop improvement and increased use of improved varieties in smallholder agriculture.Peer Reviewe
On the Mechanisms of the Kinitting Method of the Tricot Machine. (I) On the Acceleration on the Eccentric Mechanism
Get PDFThere are great needs at present for the improvement of the eccentric knitting mechanisms in the tricot machine in which difficul ties are being found in the high speed running because of the strong vibration and the inertia forces that are actuated by the clearances and the weights of the followers and cams. The author, according, tried to get rid of the present difficulty and calculated the magnitudes and the directions of the acceleration of the eccentric by the analytical and graphical method using the determinant and complex variable equations.departmental bulletin pape
On the Mechanisms of the Kinitting Method of the Tricot Machine. (I) On the Acceleration on the Eccentric Mechanism
No full textThere are great needs at present for the improvement of the eccentric knitting mechanisms
in the tricot machine in which difficul ties are being found in the high speed running
because of the strong vibration and the inertia forces that are actuated by the clearances and
the weights of the followers and cams.
The author， according， tried to get rid of the present difficulty and calculated the
magnitudes and the directions of the acceleration of the eccentric by the analytical and graphical
method using the determinant and complex variable equations
Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.
No full textN1-methyladenosine (m1A) is found at position 58 in the T-loop of many tRNAs. In yeast, the formation of this modified nucleoside is catalyzed by the essential tRNA (m1A58) methyltransferase, a tetrameric enzyme that is composed of two types of subunits (Gcd14p and Gcd10p). In this report we describe the cloning, expression and characterization of a Gcd14p homolog from the hyperthermophilic bacterium Thermus thermophilus. The purified recombinant enzyme behaves as a homotetramer of 150 kDa by gel filtration and catalyzes the site- specific formation of m1A at position 58 of the T-loop of tRNA in the absence of any other complementary protein. S-adenosylmethionine is used as donor of the methyl group. Thus, we propose to name the bacterial enzyme TrmI and accordingly its structural gene trmI. These results provide a key evolutionary link between the functionally characterized two-component eukaryotic enzyme and the recently described crystal structure of an uncharacterized, putative homotetrameric methyltransferase Rv2118c from Mycobacterium tuberculosis. Interest ingly, inactivation of the T.thermophilus trmI gene results in a thermosensitive phenotype (growth defect at 80 degrees C), which suggests a role of the N1-methylation of tRNA adenosine-58 in adaptation of life to extreme temperatures.Journal ArticleResearch Support, Non-U.S. Gov'tSCOPUS: ar.jinfo:eu-repo/semantics/publishe
Les tristesses d'un marchand : chanson en patois de Roubaix, chantée par les Enfants de la Brasserie roubaisienne / composée par Oscar Tricot
No full textAvec mode text
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