669 research outputs found

    Remodelage cardiaque dans la ville la plus haute du monde‎ : effets de l'altitude et du mal chronique des montagnes

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    Background: Despite unique adaptations to chronic hypoxic exposure, Andeans highlanders frequently develop a maladaptive syndrome , termed chronic mountain sickness (CMS), characterised by a combination of hypoxaemia, excessive erythrocytosis and various non specific symptoms. The aim of this study was to evaluate cardiac remodelling and pulmonary circulation at rest and during exercise in healthy lowlanders and highlanders and in CMS patients living in the highest city in the world La Rinconada, 5 100 m, Peru). Methods: 98 males were evaluated: 18 healthy lowlanders, 23 healthy highlanders living at 3 800 m, and 55 highlanders living at 5 100 m, among which 17 were asymptomatic (no CMS), 14 reported mild CMS and 24 reported moderate severe CMS. Cardiac remodelling was quantified by rest echocardiography. Pulmonary artery pressure (PAP) and pulmonary vascular resistance (TVR) were measured at rest and during submaximal cycling exercise. Total blood volume and haemoglobin mass were determined using the carbon monoxide rebreathing technique. Result: Heart remodelling, predominantly of the right heart, together with an elevation of resting PAP and an impairment in systolic function progressively occurred with the increase in altitude of residency. The left heart exhibited a progressive concentric remodelling with diastolic dysfunction but without systolic dysfunction. Those modifications were emphasised in moderate severe CMS patients at 5 100 m. Mean PAP was higher both at rest and during exercise in healthy highlanders at 5 100 m albeit without significant difference in TVR. On another hand, the moderate severe CMS subjects had a higher TVR at rest and a larger increase in mPAP during exercise. The right heart remodelling was significantly correlated with resting and exercise m PAP, total blood volume and arterial oxygenation. Conclusions: In the highest city in the world, healthy dwellers exhibit right heart dilatation in response to a chronically increased afterload and a left ventricle concentric remodelling with diastolic dysfunction. Those modifications are accentuated in moderate-severe CMS subjects and may enhance the risk of heart failure.Introduction : Malgré des adaptations uniques à l'hypoxie chronique, les andéens vivant en haute altitude développent fréquemment un syndrome de maladaptation, appelé mal chronique des montagnes (CMS), caractérisé par l'association d'une hypoxémie et de plusieurs symptômes aspécifiques. Le but de cette étude était d'évaluer le remodelage cardiaque et l'hémodynamique pulmonaire au repos et à l'effort chez les habitants de la ville la plus haute du monde (La Rinconada, 5100m, Pérou). Méthodes : 98 sujets ont été évalués : 18 sujets vivant en basse altitude, 23 sujets vivant à 3800m d'altitude et 55 sujets vivant à 5100m d'altitude (17 sans CMS,14 avec un CMS léger, 24 avec un CMS modéré à sévère). Le remodelage cardiaque était quantifié par une échocardiographie. Les pressions artérielles pulmonaires (PAP) et les résistances vasculaires pulmonaires (RVP) étaient mésurées au repos et lors d'un exercice submaximal à vélo. Le volume sanguin total et la masse d'hémoglobine étaient déterminés en utilisant le test de CO rebreathing. Résultats : Un remodelage cardiaque, principalement du coeur droit, associé à une élévation des PAP au repos et à une altération de la fonction systolique se développent progressivement avec l'augmentation de l'altitude de résidence. Le coeur gauche présente un remodelage concentrique progressif avec une dysfonction diastolique, mais sans dysfonction systolique. Ces modifications étaient augmentées chez les sujets souffrant d'un CMS modéré à sévère à 5 100 m. Les PAP moyennes était plus élevées au repos et à l'effort chez les habitants vivant à 5100 m. D'un autre côté, les sujets avec un CMS modéré à sévère avaient des RVP plus élevées au repos et une augmentation plus importante des PAP à l'effort. Le remodelage du ceur droit était significativement corrélé avec les PAP au repos et à l'effort, le volume sanguin total et l'oxygénation artérielle. Conclusions : Dans la ville la plus haute du monde, les habitants présentent une dilatation du ceur droit en réponse à une augmentation chronique de la post-charge et un remodelage concentrique du ventricule gauche avec une dysfonction diastolique. Ces modifications sont accentuées chez les sujets souffrant d'un CMS modéré à sévère, et peuvent augmenter le risque d'insuffisance cardiaque

    Author's gift inscription, in The heather on fire; a tale of the Highland clearances

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    This edition includes an author's gift inscription, "To Mrs John Dillon with sincere esteem Mathilde Blind".Blind, Mathilde, 1841-189

    Traiter les bidonvilles hier et aujourd’hui. Le relogement entre permanence et provisoire

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    This paper aims at analyzing the treatment of residential vulnerability by comparing slum relocation schemes in the 1960s and the 2000s. We seek to understand the links between some episodes of extension of the area of vulnerability and processes of urban transformation in both urgent and provisional forms. We show a certain continuity in slum relocation processes, wich are characterized by their tentative and precarious nature, dedicated to an identified population, and managed by specific actors. It shows the relationship between residential vulnerability and an intermediate urbanity.En comparant les dispositifs de relogement des bidonvilles dans les années 1960 et 2000 à Saint-Denis, cet article aborde un volet du traitement de la vulnérabilité résidentielle. Il s’agit de comprendre le rapport qui a pu s’établir entre des épisodes d’extension de la zone de vulnérabilité et des processus de transformation urbaine sous des formes urgentes et provisoires. Il apparaît qu’il existe des permanences dans ces dispositifs de relogement, tant concernant la forme d’habitat produit, le public identifié que les acteurs concernés. Cela rend compte de la relation existante entre la vulnérabilité résidentielle et la création d’une urbanité de l’entre-deux.Costil Mathilde, Roche Élise. Traiter les bidonvilles hier et aujourd’hui. Le relogement entre permanence et provisoire. In: Les Annales de la recherche urbaine, N°110, 2015. Ville et vulnérabilités. pp. 64-73

    Gender and pedagogics - Mathilde Vaerting, professor of educational science (Jena, 1923-1933)

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    Der Aufsatz skizziert Leben und Karriere von Mathilde Vaerting (1884-1977), der ersten Professorin für Erziehungswissenschaft in Deutschland, Jena 1923-1933. Ihr Hauptwerk „Neubegründung der Psychologie von Mann und Weib", 1921ff., wird unter Aspekten der Forschungslogik analysiert und auf Konsequenzen für die Erziehungswissenschaft befragt. Ihre Forderung nach Gleichberechtigung und Abwehr jeglicher Herrschaft werden vor dem Hintergrund heutiger feministischer Forderungen diskutiert. Im Anschluß an die Betrachtung der zeitgenössischen Rezeption Mathilde Vaertings wird die Frage aufgeworfen, inwieweit ihr Leben und ihre Karriere die Stellung der Frau in der Wissenschaft während der zwanziger Jahre (und auch später?) spiegeln. (DIPF/Orig.)The author outlines the biography and career of Mathilde Vaerting (1884-1977), the first woman to hold a chair in educational science in Germany. Her major work - Neubegründung der Psychologie von Mannund Weib (1921 fol.) - is analyzed from a methodological point of view and with respect to its implications for educational research. Vaerting\u27s demands for equal rights for women and her rejection of any kind of domination are discussed within the framework of present feminist positions. After having studied how contemporaries reacted to Mathilde Vaerting\u27s writings, the author raises the question of whether Vaerting\u27s life and career reflect the Status of women in science during the 1920s (and later on?). (DIPF/Orig.

    Effi Briest, Mathilde Möhring. The Development of Theodor Fontane's Female Characters on the Background of Women Emancipation.

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    Theodore Fontane is best known as the author of numerous women's novels, which he wrote in the last ten years of his life. This diploma thesis deals with the topic of women's emancipation on the basis of textual analysis of two latter novels by Theodore Fontane - Effi Briest and Mathilde Möhring. In the first part, it characterizes the topic of the period women's emancipation and puts the author's biography into context. In the second part, it creates the picture of position of the main women characters. The last part describes the personal development of the women characters, on the basis of which I determine how much the women's emancipation reflects in the author's work and what is his attitude towards it. This thesis deals with the interpretation of the author's intent to illustrate the creation of an advanced character like Mathilde Möhring. Key words: Theodore Fontane, women's emancipation, Effi Briest, Mathilde Möhring, development of women's characters, women's novels, interpretation, author's intent, counterpoin

    Sample validation with Roche Elecsys, Euroimmun ELISA, and NIA.

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    A) Roche Elecsys anti-SARS- CoV-2 S total Ig assay. 5 SARS-CoV-2 negative samples (purple color) with signal above the positivity threshold (>0.8) were excluded from the study. B) Euroimmun ELISA anti-S1 IgG assay. The thresholds for positivity (>1.1) and negativity (55’000 RFU) were removed from the plot and correlation calculation.</p

    Effi Briest, Mathilde Möhring. Vývoj postavy žen na pozadí dobové emancipace ve stejnojmenných románech Theodora Fontana.

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    Theodore Fontane is best known as the author of numerous women's novels, which he wrote in the last ten years of his life. This diploma thesis deals with the topic of women's emancipation on the basis of textual analysis of two latter novels by Theodore Fontane - Effi Briest and Mathilde Möhring. In the first part, it characterizes the topic of the period women's emancipation and puts the author's biography into context. In the second part, it creates the picture of position of the main women characters. The last part describes the personal development of the women characters, on the basis of which I determine how much the women's emancipation reflects in the author's work and what is his attitude towards it. This thesis deals with the interpretation of the author's intent to illustrate the creation of an advanced character like Mathilde Möhring. Key words: Theodore Fontane, women's emancipation, Effi Briest, Mathilde Möhring, development of women's characters, women's novels, interpretation, author's intent, counterpointTheodor Fontane je známý především jako autor četných ženských románů, které psal ve svém pokročilém věku. Tato práce zpracovává na základě analýzy textu téma ženské emancipace v jeho dvou pozdějších románech - Manželství Effi Briestové a Mathilda Möhringová. V první části charakterizuje téma dobové ženské emancipace a zasazuje autorovu biografii do kontextu. V druhé části utváří obraz pozice hlavních románových hrdinek. V poslední části je shrnut osobní vývoj ženských postav, na jejímž základě má být zodpovězena otázka, nakolik se ženská emancipace odráží v autorově díle a jaký je jeho postoj k ní. Práce se zároveň zabývá intepretací autorova záměru, který vytvořil postavu pokročilé Mathildy Möhringové, čímž dosáhl kontrapunktu k tomu, co doposud psal. Klíčová slova: Theodor Fontane, ženská emancipace, Effi Briest, Mathilde Möhring, vývoj ženských postav, interpretace, ženské romány, záměr autora, kontrapunktInstitute of Germanic StudiesÚstav germánských studiíFilozofická fakultaFaculty of Art

    Tunisian Politics in France: Long-Distance Activism since the 1980s

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    International audienceWhat does it mean to oppose or support an authoritarian regime from afar? During the years of Ben Ali's dictatorship in Tunisia between 1987 and 2011, diaspora activism played a key role in the developments of post-independence Tunisian politics. Centring this study on long-distance activism in France, where the majority of leftist and Islamist exile groups took refuge, Mathilde Zederman explores how this activism helps to shed new light on Tunisia's political history. Tunisian Politics in France closely explores the interactions and conflicts between different constellations of pro-regime and oppositional actors in France, examining the dynamics of what the author persuasively describes as a 'trans-state space of mobilisation'. In doing so, Zederman draws attention to the constraints and possibilities of long-distance activism. Utilising material gathered from extensive fieldwork in France and Tunisia, this study considers how the evolution of diaspora activism both challenges and reinforces the boundaries of Tunisian politics

    Book review: Photography of protest and community: the radical collectives of the 1970s by Noni Stacey

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    In Photography of Protest and Community: The Radical Collectives of the 1970s, Noni Stacey shows how a 1970s network of London-based photography collectives raised fundamental questions about the politics of photography, the role and responsibilities of photographers in relation to local communities and the uses of photography in the context of social activism. This book is a welcome addition to the expanding field of research on the photography of protest, writes Mathilde Bertrand, contributing to the ongoing documentation of this strong current in British photographic history. If you are interested in this book review, you can read an LSE RB interview with author Dr Noni Stacey. The archive of the Exit Photography Group is held at LSE Library; readers can find out more about the archive and the catalogue. Photography of Protest and Community: The Radical Collectives of the 1970s. Noni Stacey. Lund Humphries. 2020

    Piano music of Mathilde Kralik von Meyrswalden (1857-1944)

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    Thesis (D.M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at [email protected]. Thank you.This dissertation examines the life and music of Mathilde Kralik von Meyrswalden (1857-1944), with a focus on her piano solo works. This project is intended to bring new light to the forgotten late-romantic Austrian composer. As a pupil of Anton Bruckner, and as a colleague of Gustav Mahler, Kralik's style belongs to the late Romantic period in Vienna. Her musical aesthetics are similar to the styles of Schubert, Liszt, Schumann, Wolf, Mahler, and StraufS; however she had her own unique voice from the beginning of her musical career. Though she was an active composer, performer, and musical figure of her time and was recognized and respected by the Viennese society, her life and work remain greatly understudied. Chapter 1 presents a detailed biographical background of Mathilde Kralik von Meyrswalden. Chapter 2 provides a complete list of work by Mathilde Kralik. Chapter 3 depicts the political background of her time, and then discusses the situation of women as artists in Vienna between 1850 and 19 50. Chapter 4 focuses on two people in her closest circle: her elder brother, Richard Kralik, who was a renowned writer and cultural commentator; and her friend, Alice Scarlates, who was a lecturer for Roman language at the University of Vienna and lived with Kralik in the same house in Wiener Cottage-Viertel for over 30 years. Chapter 5 analyzes her 5 Klavierstiicke- Festmarsh, Triiumerei, Liedchen, Intermezzo, and Gavotte. Chapter 6 continues the analysis with her other major piano solo work: Priiludium, Passacaglia, und Fugato. Lastly, Chapter 7 discusses the public and critical reception of her music, both during her time and in the modern era. The purpose of this project is first, to discover new sounds from a past style; second, to give credit to a serious, prolific, and independent female composer, who bravely chose a career with special challenges in her time and her surroundings; third, to encourage further research and performances of Kralik's works
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