23 research outputs found

    An enrichment unit on local water resources and water conservation to supplement eighth grade earth science curriculum

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    Currently, there is no written curriculum for educating students about local water resources and water conservation practices in the Glassboro Eighth Grade Earth Science Curriculum. Utilizing all available references and agencies, (federal, state and local) the author created an enrichment unit dealing with local water resources and water conservation practices to supplement the existing Eighth Grade Science Curriculum, specifically the Geology unit of the Merrill Earth Science textbook. The lessons are hands-on activities which promote critical thinking, problem solving, and cooperative learning. Though designed for a specific audience and for a specific reason, lessons in the unit can be easily adapted by any teacher to incorporate environmental education activities in their classrooms

    The effect of dexmedetomidine on liver histopathology in a rat sepsis model: an experimental pilot study

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    BACKGROUND In this pilot study, we aimed to investigate the effect of dexmedetomidine on liver tissues during experimental sepsis by histopathological examination. METHODS The animals were allocated randomly to four groups, two of which received endotoxin. In the Sepsis Group (n:10) and Dexmedetomidine/Sepsis Group (n:10), endotoxemia was induced by E. coli lipopolysaccharide derived from E. colt 0111: B4. Animals in the Control Group (n:10) received an infusion of 0.9% saline (1.0 mL.kg(-1).hr(-1)) intravenously. The Dexmedetomidine Group (n:10) and Dexmedetomidine/Sepsis Group received a bolus injection of 0.9% saline (1.0 mL/kg), followed by dexmedetomidine administration (infusion at 5 mu g.kg(-1).hr(-1)). All rats were euthanized at the 8th hour of endotoxin infusion. Histopathological examinations were performed on liver tissues. RESULTS In the liver, central venous congestion, congestion and dilation of the hepatic sinusoids and inflammation of the portal tracts were noted in the Sepsis Group. These parameters were seen slightly in the Sepsis/Dexmedetomidine group. There was a statistically significant difference between the Sepsis and Sepsis/Dexmedetomidine Groups (p<0.001). CONCLUSION Dexmedetomidine has a protective effect on liver tissues during experimental sepsis in the rat. We propose that dexmedetomidine sedation may be useful in the therapy of the liver dysfunction associated with sepsis and in other diseases related to local or systemic inflammation

    Curcumin attenuates the organ dysfunction caused by endotoxemia in the rat

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    Objective: Curcumin has antioxidant, antitumor, and anti-inflammatory properties. However, it remains unknown whether curcumin has any protective effects on sepsis. The purpose of this study was to demonstrate whether curcumin prevents organ dysfunction in animals with sepsis. Methods: Rats were randomized into four groups. The control group (group I, n = 7) did not receive any treatment. The curcumin group (group II. n = 10) only received 1.2 g/kg of curcumin. Escherichia coli were injected into the remaining groups intraperitoneally after general anesthesia. Five hours after injection, 12 rats received placebo (group III), and 10 rats received 1.2 g/kg of curcumin (group IV) for 7 d. All rats were sacrificed on postsepsis day 8 and it midline laparotomy was performed. Livers, kidneys, and small bowels were excised for evaluation of the degree of inflammation and tissue alterations histopathologically. Results: In the liver, widespread hydropic degeneration of hepatocytes were seen in the sepsis group. There was no hydropic degeneration of hepatocytes and no portal inflammation ill the sepsis/curcumin group. With respect to the small bowel, the sepsis group showed edema and prominent intraepithelial infiltration of neutrophil leucocytes and plasma cells. Inflammation and hyperemia in the lamina propria in the sepsis/curcumin group were less than those in the sepsis group, With respect to the kidneys, the sepsis group showed severe acute tubular necrosis that was more restricted in the sepsis/curcumin group than in the sepsis group. Conclusion: curcumin reduced organ dysfunction in rats with experimentally formed sepsis. We propose that curcumin may he useful in the therapy of organ dysfunction due to sepsis, shock, and other diseases associated with local or systemic inflammation. (C) 2008 Elsevier Inc. All rights reserved

    Retroperitoneal Ciliated Foregut Cyst: A Rare Malformation

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    WOS: 000436147800015Foregut cyst (FC) is an uncommon, benign, solitary cyst comprising four layers: ciliated pseudostratified columnar epithelium, subepithelial connective tissue, smooth muscle layer, and outer fibrous capsule. FCs are classified as bronchogenic, enterogastric, or undifferentiated. Friedreich first described the lesion in 1857 and predicted its congenital origin. We present an FC that developed in the retroperitoneum and was difficult to separate from other retroperitoneal cystic mass lesions. A 27-year-old female presented with flank pain. Abdominal computed tomography revealed a cystic lesion, measuring approximately 7.8 cm in diameter, located near the posterior stomach, superior pole of the left kidney, and pancreas. Total cystectomy was performed. Macroscopic examination revealed a 7.8x6 cm unilocular cyst enclosed by a thin capsule, which contained a viscous, yellowish fluid. No solid component was observed in the lesion. The surgeon confirmed no continuity of the cyst into the surrounding organs. Microscopy revealed the cyst to comprise four layers. In focal areas, seromucous glands were observed in the wall. There was no evidence of malignancy. With these findings, this case was diagnosed as retroperitoneal ciliated FC. FC located in the abdomen or retroperitoneum is extremely rare, and few cases have been described in literature. Intraabdominal and retroperitoneal locations have been explained by the presence of pleuroperitoneal canals in the early embryonic stage. FC should be considered in the differential diagnosis of retroperitoneal cystic masses including lymphangiomas, cystic pancreatic tumors, pseudocysts, and hematomas

    Effects of phytoterapeutics on benign prostate hyperplasia

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    İyi huylu prostat büyümesi (Benign Prostat Hiperplazisi=BPH), elli yaş üstü erkeklerin ortalama üçte birinde görülen hem idrar depolama, boşaltma ve boşaltma sonrası semptomlara yol açan, hem de olguların yaşam kalitesini bozan bir durumdur. BPH’ye bağlı alt üriner sistem hastalıklarının tedavisinde fitoterapötikler uzun zamandan beri klinik uygulamalarda yer almaktadır. Bu çalışmanın amacı BPH tedavisinde en sık kullanılan fitoterapötikler olan Cucurbita pepo, Epilobium sp., Hypoxis rooperi, Lycopersicon esculentum Mill., Pinus pinaster Aiton, Pygeum africanum, Roystonea regia (Kunth) O.F. Cook, Secale cereale, Serenoa repens, Urtica dioica’nın etkinlikleri ve yapılan önemli klinik çalışmaları derlemekti

    Price volatility spillovers among agricultural commodity and crude oil markets: Evidence from the range-based estimator

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    Gözgör, Giray (Dogus Author)The paper examines the price volatility spillovers among the crude oil, soybeans, corn, wheat, and sugar futures markets over the period 1/1/2006–11/29/2013. We separately investigate the periods of the pre-crisis, the crisis, and the post-crisis in financial markets. We use the Yang-Zhang estimators for the historical volatility and find that there is a volatility sprawl from the crude oil to corn markets. T ere is also bi-directional causality between the corn and soybeans markets. In addition, we observe significant volatility spillovers from both the soybeans and the corn markets to the wheat markets. The results are also valid in a different sub-period analysis

    Loss of Consciousness Induced by a Single Dose Flurbiprofen

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    Loss of consciousness after the administration of flurbiprofen has not been reported. In this case report, we describe loss of consciousness due to the administration of one oral dosage of flurbiprofen. A 17 year-old girl without a remarkable neurologic and atopic medical history had an loss of consciousness after ingestion of flurbiprofen mg 100 mg tablet. Patient was treated successfully. This report emphasies that this complication may be seen with flurobiprofen and underlying mechanisms and therapeutic approach are discussed
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