9 research outputs found
Competencias Tecnológicas en la Formación Profesional del Músico
The professional activity of the musician is not limited to the performance of musical pieces, but the current job market demands a broad professional profile where information technologies occupy an important place as a tool for performance, research and dissemination. The research addresses the analysis of the educational context of an institution in Mexico and one in Costa Rica dedicated to the training of musicians, with a view to describing a professional profile required in the current musical field. The specific needs related to music technology were identified in the different areas: theory, analysis, musicology, composition, teaching music theory, and listening training, among others. Following a mixed methodology, the level of use and expectations of musical technologies was detected, to finally carry out a comparative analysis of the institutional opinion on professional profiles as an input for the improvement in future instructional designsLa actividad profesional del músico no se circunscribe a la ejecución de piezas musicales, sino que el mercado laboral actual demanda un perfil profesional amplio donde las tecnologías de la información ocupan un lugar importante como herramienta de ejecución, de investigación y de difusión. La investigación aborda el análisis del contexto educativo de una institución en México y una en Costa Rica dedicadas a la formación de músicos, con miras a la descripción un perfil profesional requerido en el ámbito musical actual. Se identificaron las necesidades específicas relativas a la tecnología musical en las distintas áreas: teoría, análisis, musicología, composición, enseñanza de solfeo y entrenamiento auditivo, entre otras. Siguiendo una metodología mixta se detectó el nivel de uso y expectativas de tecnologías musicales, para finalmente realizar un análisis comparativo de la opinión institucional sobre perfiles profesionales como insumo para la mejora en futuros diseños instruccionale
Competencias digitales para el seguimiento a egresados
Se presentan los principales puntos de seguimiento de egresados de artes de la Universidad Veracruzana a través de herramientas de trabajo colaborativo (Google Forms), redes sociales y otras tecnologías, presentando un análisis mixto (cuantitativo y cualitativo) de los resultados de una encuesta así como la discusión de ésta y las conclusiones generales, las cuales reflejan las necesidades que tiene el artista en el nuevo y cambiante campo laboral, lo que conlleva a la necesidad de actualización curricular por parte de la Universidad para construir el nuevo perfil del egresado en arte
Percepción de competencias digitación de competencias digitales en estudiantes y docentes universitarios mexicanos
En muy poco tiempo las nuevas Tecnologías de Información y Comunicación (TIC)
han penetrado y transformado prácticamente todos los ámbitos de la actividad
humana, impulsando el surgimiento de un nuevo estadio de nuestra civilización al
que se ha denominado Sociedad del Conocimiento.
Ante esto, se espera que las TIC ayuden a modernizar los procesos de enseñanza y
aprendizaje y hagan más atractiva la escuela para las nuevas generaciones que
viven en un mundo crecientemente digital y multimedial
Open Innovation : an Extra-Organisational Level Analysis - Systematic Literature Review
Since the publication of Open Innovation: The new imperative for creating and profiting from technology from Henry Chesbrough, the interest for Open Innovation grew dramatically in the last 15 years. According to the author, Open Innovation can be defined as “the purposive inflows and outflows of knowledge to accelerate internal innovation, and expand the markets for external use of innovation” (Chesbrough, 2006, p. 1). Many other authors joined Chesbrough in his research on Open Innovation and as a result the amount of publications concerning this topic increased quickly. However, due to the fast growth of the research stream, there is hardly any structure, which helps to define and classify the different emerging theories and studies regarding Open Innovation. Therefore, the aim of this Masters thesis is to first of all give a comprehensive overview on the Open Innovation concept and how it distinguishes from the Closed Innovation concept. During the examination of the Open Innovation model and its related theories, it became evident, that most of the research papers focused on the relationship between the firm and Open Innovation and neglected the relation between the firm and the firms stakeholders located in the Open Innovation context. Consequently, the second part of this Masters thesis consists of a systematic literature review of the extra-organisational level of the Open Innovation concept. Vanhaverbeke and Cloodt (2006, p. 276) realized that in order to structure the various Open Innovation theories, a reference framework is needed. Their framework will be used for this Masters thesis. At the intra-organisational level of this reference framework, topics such as absorptive capacity and the “Not-invented-here” syndrome are discussed. Research papers from for instance Lichtenthaler and Ernst (2006), Katz and Allen (1982) made valuable contributions to these topics. The organizational level deals with Open Innovation business models, which are discussed for example by Chesbrough and Rosenbloom (2002), and theories how companies can shift from a Closed to an Open Innovation model. The latter mentioned topics are attended e.g. by Chiaroni et al. (2010) or Fetterhoff and Voelkel (2006). The inter-organisational level addresses topics such as in- and out-licencing, corporate venture capital, joint ventures or contractual R&D agreements in an inbound and outbound Open Innovation setting. Relevant literature for this subchapter is provided for example by Tidd et al. (2005), Culpan (2014) or Dushnitsky and Lenox (2005a). At the extra-organisational level of analysis, the focus is on the firms stakeholders such as customers and users. Research papers that elaborate on consumer-generated innovations stem from Laursen and Salter (2006) or Berthon et al. (2015). Regarding users, von Hippel (1998, 2005, 2010) is the founder of the user innovation concept. The focus of the industrial, regional and societal level is on topics such as the investigation of the influence of industry development and inter-industry differences on the adoption of Open Innovation strategies (see e.g. Poot et al., 2009), local, regional and national innovation systems, and the impact of Open Innovation on citizens and public policy (see e.g. Carayannis/Campbell, 2009; Cohen et al., 2016; Miller et al., 2016). With reference to the second part of this Masters thesis, the systematic literature review of the extra-organisational level yielded in total 123 research papers. Descriptive analysis reveals that the 123 articles were published in 45 different journals. The two journals with the most publications since 2003 are the Journal of Product and Innovation Management with 11 publications and the Creativity and Innovation Management Journal with 10 published research papers. Further analysis points towards a trend of author collaborations in scientific research as merely 12 per cent of the total papers was written by a single researcher. Moreover, Füller, von Hippel and Matzler are the three researchers with the most publications with regard to the extra-organisational OI topic since 2003. Franke can be considered the most quality-driven researcher. The thematic analysis of the research papers identified five main sub-topics regarding the extra-organisational level of Open Innovation. The User Innovation sub-topic contains 44 of the 123 research papers. According to research, a user innovator is a user, who innovates a design, service or product for an improved benefit/utilization afterwards (Baldwin/von Hippel, 2011, p. 1402). Several research streams that address the User Innovation sub-topic are discussed: (1) user innovator types/characteristics, (2) motivational factors, (3) user innovator identification and (4) integration, and (5) value for the company. The second sub-topic addresses Customer/Consumer Innovation. The terms user and customer innovator are practically used synonymously in research. Hence, the differentiation between the two innovator types is difficult. Furthermore, the discussion of the Customer/Consumer Innovation sub-topic followed the same research streams as the investigation of the User Innovation sub-topic. The third sub-topic is Crowdsourcing, which is the voluntary generation of innovative solutions for a firm problem, performed by heterogeneous individuals, who are motivated to participate in problem-solving activities (Franke et al., 2013, p. 1495; Majchrzak/Malhotra, 2013, p. 258). The attended research streams of this sub-topic are about the motivations of companies to choose crowdsourcing, the motivations of users and customers to participate in crowdsourcing activities, the ideation process and the potential value of crowdsourcing for firms. Online Communities depict the fourth sub-topic and are defined as a large group of individuals, sharing the same interests, rules, norms, values and culture, and who interact regularly and voluntary over the Internet in order to find new solutions for personal or product-related needs (Schröder/Hölzle, 2010, p. 260). Besides the definition of Online Communities, different types of participants and their motivations, challenges for firms, which want to use Online Communities for their innovation processes and recommendations for overcoming these challenges, as well as the impact of Online Communities on the innovation process are discussed. The fifth and last sub-topic addresses Innovation Contests. An innovation contest is an approach that encourages a public crowd to co-creatively develop innovative solutions to a firms problem (Füller et al., 2014, p. 274; Hutter et al., 2011, p. 3). The discussed research streams focus on Innovation Contest participator types, the right contest design, toolkits and the potential value of Innovation Contests on firm innovation. Concluding, the systematic literature review revealed several future research trends. Research papers from Bugshan (2015), Ernst and Brem (2017), He and Wang (2016), and Mount and Martinez (2014) underline the value of social media for a companys innovation process. Moreover, the importance of social media will increase with technological advances and new crowdsourcing methods. In the future, companies will be able to develop products adapted for the users needs with data recorded from sensors within e.g. a users clothes (Brown, 2017, p. 826). Consequently, questions regarding the ethical use of crowdsourcing methods will arise (Standing/Standing, 2018, p. 74). Companies and researchers will have to think about solutions how on the one side, companies can use these new technologies to satisfy customer needs more effectively, and how on the other side, customer privacy can be secured. Finally, the examination of the found research articles revealed that the large majority of researchers focused on the front end stage of the innovation process. However, it is clear that research on the commercialization stage is more difficult, as users and customers are not involved in a companys business relationships in general. Hence, it is probable that there simply is hardly anything that researchers could investigate on the commercialization stage of innovation and therefore, the proportion of research in this area will not increase in the near future.submitted by Daniel Rathgeb, BScMasterarbeit Universität Linz 201
Modeling the brain morphology distribution in the general aging population
Both normal aging and neurodegenerative diseases such as Alzheimer's disease cause morphological changes of the brain. To better distinguish between normal and abnormal cases, it is necessary to model changes in brain morphology owing to normal aging. To this end, we developed a method for analyzing and visualizing these changes for the entire brain morphology distribution in the general aging population. The method is applied to 1000 subjects from a large population imaging study in the elderly, from which 900 were used to train the model and 100 were used for testing. The results of the 100 test subjects show that the model generalizes to subjects outside the model population. Smooth percentile curves showing the brain morphology changes as a function of age and spatiotemporal atlases derived from the model population are publicly available via an interactive web application at agingbrain.bigr.nl.</p
Distinct impact of CURLY LEAF and SWINGER on the Arabidopsis Histone H3 Lysine 27 trimethylation pattern is linked to the underlying genetic code
Polycomb Group Proteins (PcG) are a conserved class of transcriptional repressors
in animals and plants, controlling the expression of hundreds of genes. Specifically,
they repress gene expression by histone H3 trimethylation at lysine 27 (H3K27me3)
via the Polycomb Repressive Complex 2 (PRC2). In Arabidopsis thaliana CURLY LEAF
(CLF), a PRC2 methyltransferase, is partially redundant with the closely related protein
SWINGER (SWN). The phenotype of clf null mutant plants is less severe than the
phenotype of clf/swn double mutants. Plants that are mutated in swn exhibit no obvious
phenotype. The large degree of sequence conservation of both CLF and SWN
throughout the plant kingdom, suggests that they have distinct and conserved functions
in plant development.
I set out to identify the individual target genes of CLF and SWN and to uncover their
functions. To this end, I used chromatin immunoprecipitation followed by deep sequencing
to create genome-wide H3K27me3 profiles of wild type, clf and swn seedlings.
The three genotypes share many H3K27me3 target regions but they exhibit partially
distinct methylation profiles. In clf null mutants, H3K27me3 is significantly reduced at
643 genes, indicating that at these genes CLF is the major catalytic component of PRC2.
A part of the CLF dependent genes is significantly physically clustered along chromosomes
and surprisingly, 60% of CLF dependent genes contain a conserved AAACCCTA
or telo box which has been previously reported to enhance transcription. Unexpectedly,
reduction of H3K27me3 in clf mutant plants does not correlate frequently
with an increase of gene expression. The swn mutation can either have the same effect,
oppose or contribute to the effect of clf on the expression of these genes. Moreover, in
swn null mutants, H3K27me3 seems to be slightly increased in 294 genes compared to
wild-type. These results suggest that the interplay between CLF and SWN might be
important to establish wild-type-like H3K27me3 and expression levels. Finally, in swn,
expression of some CLF dependent genes changes dramatically, although H3K27me3
is unaffected. This indicates that SWN might have an H3K27me3 independent function.
In short, these results demonstrate that CLF and SWN have partially distinct effects
on the Arabidopsis thaliana H3K27me3 pattern and that their function is linked to the
underlying genetic code. SWN might control expression in a H3K27me3 independent
pathway and the interplay between CLF and SWN is presumably important to maintain
establish wild-type-like H3K27me3 and expression levels
Evaluación de la Matriz de Alginato de Sodio y Maltodextrina Para la Encapsulación de Lactobacillus Casei
DigitalLactobacillus Casei identificado como una bacteria con efectos benéficos a la salud humana debido a que contribuyen al equilibrio de la microbiota intestinal y potencian el sistema inmunológico previniendo trastornos intestinales y ha sido reconocida como bacteria probiótica principalmente en matrices líquidas. Se ha reportado cómo es su proceso de liberación y sus características en diversos procesos de encapsulación, pero no se encuentra literatura acerca de su supervivencia por un periodo de tiempo mayor a 8 días. Siendo necesario conocer como afecta el sistema de encapsulación al microorganismo en un periodo de tiempo mayor y saber su distribución en la cápsula.
El objetivo del presente trabajo fue identificar la distribución, viabilidad y liberación del microorganismo encapsulado en alginato y maltodextrina mediante el método por goteo en tres concentraciones con el fin de conocer sus propiedades mediante ensayos en placas de Petri para observar la distribución celular en las cápsulas obtenidas y simulación de supervivencia en jugos gástricos simulados a lo largo de 21 días. Se obtuvo cápsulas rígidas y con características físicas adecuadas en las tres concentraciones donde sin diferencias aparentes en cuanto forma, textura o color, posteriormente fueron sometidas a pruebas de interacción obteniendo un fenómeno de dosis dependiente donde a mayor concentración inicial, mayor presencia de microorganismo en la matriz superficial de las cápsulas corroborado con los resultados obtenidos mediando las micrografías mediante el microscópio electrónico de barrido (SEM) y el crecimiento alrededor de las cápsulas por medio de su siembra directa. Los resultados obtenidos en la prueba de vialidad se corroboraron por medio de la sobrevivencia a jugos gástricos simulados logrando concluir que el microorganismo encapsulado está usando la maltodextrina como fuente de energía dentro de la matriz, logrando establecer un tiempo de vida útil de 21 días permitiendo su aplicación en futuros productos alimenticios.Lactobacillus Casei has been identified as a bacterium with beneficial effects on human health because it contributes to the balance of the intestinal microbiota and boosts the immune system preventing intestinal disorders and has been recognized as a probiotic bacterium mainly in liquid matrices. It has been reported how its release process is and its characteristics in different encapsulation processes, but there is no literature about its survival for a period of time longer than 8 days. It is necessary to know how the encapsulation system affects the microorganism in a longer period of time and to know its distribution in the capsule.
The objective of the present work was to identify the distribution, viability and release of the microorganism encapsulated in alginate and maltodextrin by the drip method in three concentrations in order to know its properties by means of tests in Petri dishes to observe the cell distribution in the capsules obtained and simulation of survival in simulated gastric juices for 21 days. Rigid capsules were obtained with adequate physical characteristics in the three concentrations where there were no apparent differences in shape, texture or color, then they were subjected to interaction tests obtaining a dose-dependent phenomenon where the higher the initial concentration, the greater the presence of microorganisms in the surface matrix of the capsules, corroborated with the results obtained by measuring the micrographs using the scanning electron microscope (SEM) and the growth around the capsules by direct seeding. The results obtained in the viability test were corroborated by means of the survival to simulated gastric juices, concluding that the encapsulated microorganism is using the maltodextrin as a source of energy inside the matrix, establishing a useful life time of 21 days, allowing its application in future food products.Introducción .................................................................................................................................. 16
Pregunta de Investigación ............................................................................................................. 19
Justificación .................................................................................................................................. 20
Marco Teórico ............................................................................................................................... 22
Bacterias Ácido-Lácticas (BAL). .................................................................................................. 22
Generalidades de las Bacterias Ácido-Lácticas (BAL). ............................................................... 22
Características Fermentativas. ...................................................................................................... 22
Mecanismos de Acción de Bacterias Ácido-Lácticas. .................................................................. 23
Género Lactobacillus. ................................................................................................................... 24
Lactobacillus Casei ....................................................................................................................... 25
Mecanismo de Acción de Lactobacillus Casei. ............................................................................. 26
Usos Industriales. .......................................................................................................................... 26
Actividad Probiótica de Lactobacillus Casei. ............................................................................... 27
Tolerancia a Sales Biliares ............................................................................................................ 28
Lactobacillus Casei como Probiótico............................................................................................ 28
Encapsulación. .............................................................................................................................. 29
Aplicaciones. ................................................................................................................................. 30
Métodos de Encapsulación ............................................................................................................ 31
Sistema por Goteo o Extrusión. .................................................................................................... 31
Sustancias que se Recubren. ......................................................................................................... 32
Materiales de Recubrimiento ........................................................................................................ 33
Alginato......................................................................................................................................... 34
Alginato de Sodio. ........................................................................................................................ 34
Maltodextrina. ............................................................................................................................... 35
Marco Legal .................................................................................................................................. 36
Estado del Arte .............................................................................................................................. 37
Objetivos ....................................................................................................................................... 41
Objetivo General ........................................................................................................................... 41
Objetivos Específicos .................................................................................................................... 41
Metodología .................................................................................................................................. 42
Diseño de Estudio ......................................................................................................................... 42
Metodología .................................................................................................................................. 42
Materiales y Métodos .................................................................................................................... 43
Obtención de la Cepa. ................................................................................................................... 43
Equipos y Materiales de Laboratorio. ........................................................................................... 43
Formulación de la Matriz de Encapsulación de Alginato de Sodio Y Maltodextrina de Lactobacillus Casei ....................................................................................................................... 43
Obtención de Biomasa de Lactobacillus Casei. ............................................................................ 43
Encapsulación de Lactobacillus Casei En Alginato y Maltodextrina. .......................................... 44
Morfología de Lactobacillus Casei Encapsulado en Alginato y Maltodextrina............................ 45
Interacción Microorganismo Encapsulado con la Superficie del Medio de Cultivo. ................... 46
Estimación de la Viabilidad de Lactobacillus Casei Encapsulado en la Matriz de Alginato de Sodio y Maltodextrina................................................................................................................... 46
Viabilidad Preliminar de Lactobacillus Casei Encapsulado. ........................................................ 46
Identificación de la Resistencia en la Matriz Encapsulada para la Liberación de Lactobacillus Casei. ............................................................................................................................................. 47
Sobrevivencia Probiótica a Jugos Intestinales Simulados. ........................................................... 47
Análisis de Resultados .................................................................................................................. 48
Resultados y Discusión ................................................................................................................. 49
Determinación de la Distribución de Lactobacillus Casei Encapsulado en Alginato de Sodio y Maltodextrina ................................................................................................................................ 49
Obtención de Biomasa de Lactobacillus Casei. ............................................................................ 49
Encapsulación de Lactobacillus Casei en Alginato y Maltodextrina. ........................................... 49
Morfología de Lactobacillus Casei Encapsulado en Alginato y Maltodextrina............................ 51
Interacción Microorganismo Encapsulado con la Superficie del Medio de Cultivo. ................... 53
Estimación de la Viabilidad de Lactobacillus Casei Encapsulado en la Matriz de Alginato de Sodio y Maltodextrina................................................................................................................... 55
Viabilidad Preliminar de Lactobacillus Casei Encapsulado. ........................................................ 55
Identificación de la Resistencia en la Matriz Encapsulada para la Liberación de Lactobacillus Casei. ............................................................................................................................................. 60
Sobrevivencia Probiótica a Jugos Intestinales Simulados. ........................................................... 60
Recuento UFC/mL ........................................................................................................................ 62
Conclusiones ................................................................................................................................. 66
Recomendaciones ......................................................................................................................... 68
Apéndices ...................................................................................................................................... 88PregradoMicrobiólogo Industria
8º Seminario Internacional del Sistema de Información de Estudiantes, Egresados y Empleadores (SI EEE)
Compendio derivado del 8º Seminario Internacional del Sistema de Información de Estudiantes, Egresados y Empleadores (SI EEE), titulado «¿Hacia dónde vamos? Prospectiva en los estudios de seguimiento de trayectorias, donde a través de los 18 trabajos 37 autores adscritos a nueve universidades exploran cómo las instituciones de educación superior están integrando competencias transversales y adoptando nuevas metodologías pedagógicas para formar profesionales capaces de enfrentar un entorno laboral cambiante y desafiante. Así es que este trabajo, no solo proporciona una visión crítica de los esfuerzos realizados hasta la fecha, sino que también proyecta caminos para el futuro de la educación superior. Reafirma la necesidad de adoptar enfoques innovadores en los estudios de seguimiento, como herramientas clave para mejorar la planificación estratégica en las universidades y asegurar que la formación de los profesionales esté alineada con las demandas de un mundo cada vez más complejo e impredecible. A lo largo de sus páginas, este libro no solo recoge investigaciones y análisis sobre las experiencias de diversas instituciones de educación superior de nuestro país, sino que también ofrece un espacio para reflexionar sobre el futuro de los estudios de seguimiento de trayectorias. La prospectiva, como herramienta de planificación, permite anticipar los cambios y desafíos que enfrentará la educación superior en el mediano y largo plazo, asegurando que las universidades continúen siendo relevantes y capaces de formar a las y los profesionales que el mundo demanda.Lorena Oliver Villalobos, coordinadora; José Ángel Hernández Rodríguez, Presidente del comité organizador 8.º Seminario SI EEE; Javier Emmanuel Ortiz Ruiz, cuidado de la edición y corrección de estilo; Juan Manuel Galindo Medina, diseño editorial y gráfico
“En los bordes del archivo: escrituras periféricas, escrituras efímeras en los Virreinatos de Indias”
En los bordes del archivo es el sitio web de "En los bordes del archivo: escrituras periféricas, escrituras efímeras en los Virreinatos de Indias”, proyecto coordinado entre dos equipos de investigación de la Universidad Complutense de Madrid (UCM) y del Consejo Superior de Investigaciones Científicas (CSIC).© En los bordes del archivo - 2017. Algunos derechos reservados. Licencia Creative Commons.. Consulta realizada en 2019-03-22.La finalidad que orienta el Proyecto Coordinado “En los bordes del archivo: escrituras periféricas, escrituras efímeras en los Virreinatos de Indias” queda definida en la voz que encabeza su título, estudiada en relación con la escritura hispanoamericana colonial y abordada desde una comprensión amplia del término, no sólo en su sentido más positivista, en tanto acumulación o repositorio de documentos para la conformación de la verdad historiográfica y la imposición del poder imperial, sino en las acepciones paralelas de “lugar de la memoria” y de “metáfora epistémica”, de herramienta que permite la interpretación “arqueológica” de los saberes.Peer reviewe
