186,797 research outputs found
Un percorso all'interno del manuale (in Peter STOTZ - Francesco SANTI - Paolo GARBINI - Luigi G. G. RICCI, Il latino nel Medioevo nella visione di Peter Stotz - Verona, 22 maggio 2014. STUDI MEDIEVALI, vol. 55, p. 653-682)
The article is composed of four presentations. P. Stotz illustrates
the genesis and the intentions of his Handbuch zur Sprache des lateinischen
Mittelalters, based on the census and the study of a number of linguistic facts and
expressive conventions, which are documented in the Latin of the Middle
Ages. The heuristic principles that have guided the work are argued. F. Santi
notes the importance of the conclusions of Stotz about the vitality of Latin in
the Middle Ages and the variety of performances that for the Latin language
were tested in the Middle Ages; it is placed in relation to some literary
situations and to plurilinguistic condition of the medieval culture. P. Garbini
detects the systematic approach and the intelligent and open problematic of the
survey conducted by Stotz, which offers much more than it promises: the
Handbuch posed in new and polishes terms the issue of continuity /
discontinuity of the Latin language between Antiquity and the Middle Ages, as
well as the theme of the vitality of Latin in the Middle Ages. L. Ricci proposes
a path of study inside the Handbuch devoted to the theme of the Latin
Christians from Antiquity to the Renaissance, focusing in particular on some
examples in the attitude of the Humanists regard to the Latin of the Bible, also
proposing a comparison between the text of the Vulgata and the translation by
Sebastian Castellio (1515-1563)
From cell-surface receptors to higher learning: a whole world of experience
In the last decade it has become en vogue for cognitive comparative psychologists to study animal behavior in an ‘integrated’ fashion to account for both the ‘innate’ and the ‘acquired’. We will argue that these studies, instead of really integrating the concepts of ‘nature’ and ‘nurture’, rather cement this old dichotomy. They combine empty nativist interpretation of behavior systems with blatantly environmentalist explanations of learning. We identify the main culprit as the failure to take development seriously. While in some areas of biology interest in the relationship between behavior and development has surged through topics such as extragenetic inheritance, niche construction, and phenotypic plasticity, this has gone almost completely unnoticed in the study of animal behavior in comparative psychology, and is frequently ignored in ethology too. The main aims of this paper are to clarify the relationship between the concepts of learning, experience, and development, and to investigate whether and how all three concepts can be usefully deployed in the study of animal behavior. This will require the full integration of the psychological study of behavior into biology, and of the idea of learning into a wider concept of experience. We lay out how, in a systems view of development, learning may just appear as one among many processes in which experience influences behavior. This new synthesis should help to overcome the age-old dualism between innate and acquired. It thereby opens up the possibility of developing scientifically more fruitful distinctions
2001 and all that: a tale of a third science
The paper describes the change from molecular genetics to postgenomic biology. It focuses on phenomena in the regulation of gene expression that provide a break with the central dogma, according to which sequence specificity for a gene product must be template derived. In its place we find what is called here ‘constitutive molecular epigenesis’. Its three classes of phenomena, which I call sequence ‘activation’, ‘selection’ and ‘creation’, are exemplified by processes such as transcriptional activation, alternative cis- and trans-splicing, and RNA editing. These phenomena support the following main theses of the paper: 1. Other molecular resources share the causal role of ‘genes’: the ‘causal specificity’ for the linear sequence of any gene product is distributed between the coding sequence, cis-acting sequences, trans-acting factors, environmental signals, and the contingent history of the cell (the cellular code) (thesis of distributed causal specificity). 2. These multiple and overlapping processing and targeting mechanisms amplify the repertoire of RNA and protein products specified through the eukaryotic genome, expanding the possibilities specified by the literal code of DNA (thesis of genetic underdeterminism). 3. These mechanisms of gene expression change the focus of postgenomic research from single molecules and their molecular, biochemical and intrinsic function to their cellular, constituent, component or contextual function due to their recruitment and organization in complex cellular networks. In other words, all agents involved in the regulation of gene expression, including DNA, must interact with other agents to achieve full specificity, which is imposed by regulated recruitment and combinatorial control (theses of regulated recruitment and of system analysis). I conclude from these three main theses that the complexity of higher organisms lies not in its number of genes but in the flexibility, versatility and reactivity of its whole genome
"Brüderliche Eintracht" - Das gelehrte Zürich während des Reformationsjahrhunderts. Aus Johann Heinrich Hottingers "Schola Tigurinorum Carolina" (1664)
Le ’Derivazioni’ di Uguccione da Pisa. Atti dell’incontro di studi all’Università di Zurigo, 10 febbraio 2006
Tracking the Shift to 'Postgenomics'
Current knowledge about the variety and complexity of the processes that allow regulated gene expression in living organisms calls for a new understanding of genes. A ‘postgenomic’ understanding of genes as entities constituted during genome expression is outlined and illustrated with specific examples that formed part of a survey research instrument developed by two of the authors for an ongoing empirical study of conceptual change in contemporary biology
Peter Stotz. Ardua spes mundi. Studien zu lateinischen Gedichten aus Sankt Gallen
Hudry Françoise. Peter Stotz. Ardua spes mundi. Studien zu lateinischen Gedichten aus Sankt Gallen. In: Scriptorium, Tome 33 n°2, 1979. p. 346
Handbuch zur lateinischen Sprache des Mittelater. III. Lautlehre, Stotz, P. (p. 274-279)
Peter Stotz. Ardua spes mundi. Studien zu lateinischen Gedichten aus Sankt Gallen
Hudry Françoise. Peter Stotz. Ardua spes mundi. Studien zu lateinischen Gedichten aus Sankt Gallen. In: Scriptorium, Tome 33 n°2, 1979. p. 346
Genes in the postgenomic era
We outline three very different concepts of the gene - 'instrumental', 'nominal', and 'postgenomic'. The instrumental gene has a critical role in the construction and interpretation of experiments in which the relationship between genotype and phenotype is explored via hybridization between organisms or directly between nucleic acid molecules. It also plays an important theoretical role in the foundations of disciplines such as quantitative genetics and population genetics. The nominal gene is a critical practical tool, allowing stable communication between bioscientists in a wide range of fields grounded in well-defined sequences of nucleotides, but this concept does not embody major theoretical insights into genome structure or function. The post-genomic gene embodies the continuing project of understanding how genome structure supports genome function, but with a deflationary picture of the gene as a structural unit. This final concept of the gene poses a significant challenge to conventional assumptions about the relationship between genome structure and function, and between genotype and phenotype
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