74 research outputs found

    Annotated record of the detailed examination of Mn deposits from the Danish Ingolf-Expedition

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    The author analysed a collection of 91 tub-specimens, taken during the two voyages of the Ingolf-expedition in the summers of 1895 and 1896

    Combined analysis of data from two granddaughter designs: A simple strategy for QTL confirmation and increasing experimental power in dairy cattle

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    A joint analysis of five paternal half-sib Holstein families that were part of two different granddaughter designs (ADR- or Inra-design) was carried out for five milk production traits and somatic cell score in order to conduct a QTL confirmation study and to increase the experimental power. Data were exchanged in a coded and standardised form. The combined data set (JOINT-design) consisted of on average 231 sires per grandsire. Genetic maps were calculated for 133 markers distributed over nine chromosomes. QTL analyses were performed separately for each design and each trait. The results revealed QTL for milk production on chromosome 14, for milk yield on chromosome 5, and for fat content on chromosome 19 in both the ADR- and the Inra-design (confirmed within this study). Some QTL could only be mapped in either the ADR- or in the Inra-design (not confirmed within this study). Additional QTL previously undetected in the single designs were mapped in the JOINT-design for fat yield (chromosome 19 and 26), protein yield (chromosome 26), protein content (chromosome 5), and somatic cell score (chromosome 2 and 19) with genomewide significance. This study demonstrated the potential benefits of a combined analysis of data from different granddaughter designs.Jörn Bennewitz, Norbert Reinsch, Cécile Grohs, Hubert Levéziel, Alain Malafosse, Hauke Thomsen, Ningying Xu, Christian Looft, Christa Kühn, Gudrun A. Brockmann, Manfred Schwerin, Christina Weimann, Stefan Hiendleder, Georg Erhardt, Ivica Medjugorac, Ingolf Russ, Martin Förster, Bertram Brenig, Fritz Reinhardt, Reinhard Reents, Gottfried Averdunk, Jürgen Blümel, Didier Boichard and Ernst Kal

    Roberto Gerhard: explorer and synthesist

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    There is a general perception that Gerhard’s late, modernist, style was due to a radical change of direction around the time of his First Symphony. This thesis argues that in fact several important elements integral to this ’new’ style are traceable in works as early as Dos apunts and Seven Haiku of 1921-22, and that during the intervening years Gerhard was exploring, expanding and accumulating the techniques which eventually enabled him to realise the potential of his sonic imagination. The first part of the thesis will discuss Gerhard’s origins in early twentieth century Catalonia, during the Catalan revival, with its modernisme and noucentisme, and the way in which these factors are reflected in his attitudes. In the second section the works selected will be placed in a biographical and musical context and analysed in order to demonstrate three aspects of his works. The first is that Gerhard approached each one as a separate exercise, using different methods in the most appropriate manner and disregarding questions of dogma. The second, that many of these techniques originate in the practices of the preceding generation, particularly Schoenberg, Stravinsky, Pedrell and Bartók, in addition to absorbing and applying significant elements from Catalan and Spanish traditional music. Comparators will be cited to demonstrate these facts. The final intent is to show that as the methods are applied they are explored and expanded to meet his own particular requirements and the resulting synthesis equipped him to realise their potential in his late style, fully exploited for the first time in the first movement of the First Symphony. This thesis deals with compositions preceding this work in order to demonstrate that despite the apparently disparate nature of Gerhard’s output between 1921 and 1953 there is a consistent attitude in his approach extending into the later stages of his life

    Mapping of a milk production quantitative trait locus to a 1.056 Mb region on bovine chromosome 5 in the Fleckvieh dual purpose cattle breed

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    Abstract Background In a previous study in the Fleckvieh dual purpose cattle breed, we mapped a quantitative trait locus (QTL) affecting milk yield (MY1), milk protein yield (PY1) and milk fat yield (FY1) during first lactation to the distal part of bovine chromosome 5 (BTA5), but the confidence interval was too large for positional cloning of the causal gene. Our objective here was to refine the position of this QTL and to define the candidate region for high-throughput sequencing. Methods In addition to those previously studied, new Fleckvieh families were genotyped, in order to increase the number of recombination events. Twelve new microsatellites and 240 SNP markers covering the most likely QTL region on BTA5 were analysed. Based on haplotype analysis performed in this complex pedigree, families segregating for the low frequency allele of this QTL (minor allele) were selected. Single- and multiple-QTL analyses using combined linkage and linkage disequilibrium methods were performed. Results Single nucleotide polymorphism haplotype analyses on representative family sires and their ancestors revealed that the haplotype carrying the minor QTL allele is rare and most probably originates from a unique ancestor in the mapping population. Analyses of different subsets of families, created according to the results of haplotype analysis and availability of SNP and microsatellite data, refined the previously detected QTL affecting MY1 and PY1 to a region ranging from 117.962 Mb to 119.018 Mb (1.056 Mb) on BTA5. However, the possibility of a second QTL affecting only PY1 at 122.115 Mb was not ruled out. Conclusion This study demonstrates that targeting families segregating for a less frequent QTL allele is a useful method. It improves the mapping resolution of the QTL, which is due to the division of the mapping population based on the results of the haplotype analysis and to the increased frequency of the minor allele in the families. Consequently, we succeeded in refining the region containing the previously detected QTL to 1 Mb on BTA5. This candidate region contains 27 genes with unknown or partially known function(s) and is small enough for high-throughput sequencing, which will allow future detailed analyses of candidate genes.</p

    PERCEPTRON VERSUS AUTOMATON∗

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    We study the finitely repeated prisoner’s dilemma in which the players are restricted to choosing strategies which are implementable by a machine with a bound on its complexity. One player must use a finite automaton while the other player must use a finite perceptron. Some examples illustrate that the sets of strategies which are induced by these two types of machines are different and not ordered by set inclusion. The main result establishes that a cooperation in almost all stages of the game is an equilibrium outcome if the complexity of the machines players may use is limited enough. This result persists when there are more than T states in the player’s automaton, where T is the duration of the repeated game. We further consider the finitely repeated prisoner’s dilemma in which the two players are restricted to choosing strategies which are implementable by perceptrons and prove that players can cooperate in most of the stages provided that the complexity of their perceptrons is sufficiently reduced.

    Die Krise der Subjektivität - und die Antworten darauf. Eine transzendentaltheoretische Betrachtung

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    The essay points to the topic of subjectivity against the background of contemporary crisis of subject. The Author highlights three stages or levels within the conceptualizations of subjectivity; all of them have to do with an absolute instance. Then he shortly sketches the different points of view emerging within the field of philosophical approach to subjectivity, from Aristotle's ypokeimenon through Decartes' Cogito to the modern understanding of subject as pivot of the world-of-life. Finally it is faced the topic of the Absolute Subject in the frame of Philosophy of Religion, where it is at stake the question of God's reality

    Mapping Deportation Corridors - Case Study of Public-Private Interaction and Industries of Forced Removal in Hamburg, Germany

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    In 2017, a total of 23.966 people were deported from Germany to 115 different countries around the globe. The map on the title page shows these “destinations” of forced removal. This case study presents and analyzes some significant changes in the German deportation system that occurred from 2012-2017 and the role of private actors in this context. Deportations connect different physical, legal, and political spaces and places and involve a wide range of actors, outside the ‘inner circle’ of state officials and people who are subject to forced removal. The role of private actors involved in the deportation system has received little or no attention in academic literature thus far. To address this gap, the author explores changes in the deportation corridors (Drotbohm &amp; Hasselberg 2015) that connect the city-state of Hamburg, Germany with destinations of forced removal from the perspective of a participant observer. What role do private actors play in this highly politicized field? Who profits financially from the state-sanctioned practice of deportation? What does the privatization of parts of the deportation system entail in terms of transparency and democracy? This paper addresses these and other questions based on the thesis that deportation is becoming a business in and of itself. This study found that private actors play a significant role in the marketization, humanitarianization, and digitization of parts of the German deportation system. Seeking “innovative concepts” and “solutions” to problems related to deportation, public actors helped create markets in which private firms are competing. The city of Hamburg, the German Federal Government, and the EU mobilized financial resources, aiming at creating more effective deportation systems. These financial flows connect public actors with management consultancies (delivering “expert”-knowledge), software companies, (delivering surveillance technology), and development companies and NGOs, who both play the role of humanitarian actors in emerging transnational return networks. Some of the transformation processes are related to the deterioration of the quality of asylum procedures and the intensification of the deportation policy in Hamburg and Germany respectively. At the same time, this transformation is related to the enhancement of the status of Appeals Courts, and to new counter strategies employed by deportees and activists who challenge the deportation regime

    Ambiguity

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    Ambiguity refers to a decision situation under uncertainty when there is incomplete information about the likelihood of events. Different formal models of this notion have been developed with differing implications about the representation of ambiguity and ambiguity aversion.

    Bovine polledness

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    The persistent horns are an important trait of speciation for the family Bovidae with complex morphogenesis taking place briefly after birth. The polledness is highly favourable in modern cattle breeding systems but serious animal welfare issues urge for a solution in the production of hornless cattle other than dehorning. Although the dominant inhibition of horn morphogenesis was discovered more than 70 years ago, and the causative mutation was mapped almost 20 years ago, its molecular nature remained unknown. Here, we report allelic heterogeneity of the POLLED locus. First, we mapped the POLLED locus to a ∼381-kb interval in a multi-breed case-control design. Targeted re-sequencing of an enlarged candidate interval (547 kb) in 16 sires with known POLLED genotype did not detect a common allele associated with polled status. In eight sires of Alpine and Scottish origin (four polled versus four horned), we identified a single candidate mutation, a complex 202 bp insertion-deletion event that showed perfect association to the polled phenotype in various European cattle breeds, except Holstein-Friesian. The analysis of the same candidate interval in eight Holsteins identified five candidate variants which segregate as a 260 kb haplotype also perfectly associated with the POLLED gene without recombination or interference with the 202 bp insertion-deletion. We further identified bulls which are progeny tested as homozygous polled but bearing both, 202 bp insertion-deletion and Friesian haplotype. The distribution of genotypes of the two putative POLLED alleles in large semi-random sample (1,261 animals) supports the hypothesis of two independent mutations

    On the trail of participation research. Historical developments and main content

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    Seit fast 120 Jahren existiert eine Teilnahmeforschung, deren Entwicklung oft analog zu den sich wandelnden Konzepten der Erwachsenenbildung verlief. Der folgende Beitrag möchte diese Entwicklungsstränge in ihrem historischen Verlauf und ihren inhaltlichen Schwerpunktsetzungen für den Diskurs in Österreich und Deutschland aufzeigen, verzahnen und gewichten. Anschließend werden Herausforderungen diskutiert, die sich der Teilnahmeforschung gegenwärtig stellen: die hinterfragbare Validität der empirischen Verfahren, die heterogenen Logiken der Teilnahme bzw. Nichtteilnahme sowie die Expansion an digitalen Lernformen und -möglichkeiten. Denn nicht zuletzt nehmen Personen mit höheren Schulabschlüssen ihr informelles Lernen viel stärker als Lernen wahr als Personen mit geringeren schulischen Abschlüssen, die entgegen ihrer realen Praxis sich damit unbewusst selbst als „Nichtlernende“ positionieren. Und angesichts der Explosion an digitalen Lernmöglichkeiten stellt sich, wie der Autor ausführt, die gleiche Ausgangsfrage wie schon vor 120 Jahren: Was kann getan werden, damit diese Lernmöglichkeiten für möglichst alle offenstehen und auch eine entsprechende Qualität gewährleistet wird? (DIPF/Orig.)For almost 120 years, participation research has existed and its development has often been analogous to the changing concepts of adult education. The following article aims to show, link and evaluate these strands of development in their historical sequence and their areas of emphasis in the discourse in Austria and Germany. Next, challenges currently facing participation research are discussed: the questionable validity of empirical methods, the heterogeneous logic of participation or non-participation as well as the expansion of digital forms of and opportunities for learning. People with more schooling are much more aware of informal learning as learning than people with less schooling, who unconsciously identify themselves as “non-learners” despite their actual experience. In light of the explosion in digital learning opportunities, the author explains, the same basic question arises that did 120 years ago: What can be done so that these learning opportunities are open to as many people as possible while a certain level of quality is guaranteed? (DIPF/Orig.
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