231 research outputs found

    sj-docx-1-npx-10.1177_1934578X211068926 - Supplemental material for Isolation of Antimalarial Agents From Indonesian Medicinal Plants: <i>Swietenia mahagoni</i> and <i>Pluchea indica</i>

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    Supplemental material, sj-docx-1-npx-10.1177_1934578X211068926 for Isolation of Antimalarial Agents From Indonesian Medicinal Plants: Swietenia mahagoni and Pluchea indica by Ari S. Nugraha, Yoshinta D. Purnomo, Antonius N. Widhi Pratama, Bawon Triatmoko, Rudi Hendra, Hendris Wongso, Vicky M. Avery and Paul A. Keller in Natural Product Communications</p

    Lithofacies and depositional environment spanning the Cretaceous-Paleogene boundary on the New Jersey coastal plain

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    The sedimentary record spanning the Cretaceous-Paleogene (K/Pg) boundary was examined in outcrop and in seven cores recovered from a 50 km long transect along the outcrop belt on the New Jersey coastal plain. The objectives were to: (1) conduct a high-resolution study of the K/Pg lithofacies, (2) document spatial and temporal changes in composition and texture of the sediments, and (3) interpret any changes in the depositional environment across this important geological boundary when a mass extinctions occurred. Analyses include core description, textural, petrographic, microprobe, and XRD analyses. Five lithofacies were interpreted in the Upper Cretaceous sediments and three lithofacies were recognized from the lowermost Paleogene deposits. Microprobe studies show the chemistry of Upper Cretaceous and lowermost Paleogene glauconite are identical (~7-8% K2O), but their color difference may suggest different redox condition. XRD analyses show the Upper Cretaceous clay contains more land-derived detritus than the lowermost Paleogene clay. The following sequence of events is interpreted from the sediment record spanning the K/Pg boundary: (1) deposition in near-shore setting and slow sedimentation in middle shelf when sea level was falling, albeit still shelfal depth; (2) deposition of K/Pg lithofacies when sea level was falling possibly creating a diastem but not a sequence boundary, per se; (3) a transgression above the K/Pg boundary; and (4) deposition in middle shelf possibly with decreased ocean productivity and a more reducing environment. There is no sedimentological evidence above the K/Pg boundary, suggesting tsunami-related deposition associated with a bolide impact. Either a tsunamite was eliminated by bioturbation, or NJCP was too far from the impact site to be affected. A transgressive lag, instead, was formed by normal sedimentation during the subsequent transgression in the early Paleocene.M.S.Includes bibliographical referencesby Hendra Wahyud

    Ekstraksi Karotenoid dari Minyak Buah Merah (Pandanus conoideus) dengan Metode Kromatografi Kolom Kilas

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    Karotenoid merupakan salah satu pigmen alami yang berfungsi sebagai antioksidan yang baik sehingga sering dijadikan sebagai suplemen. Penelitian ini bertujuan mengoptimisasi proses ekstraksi karotenoid dari minyak buah merah (Pandanus conoideus) dengan metode kromatografi kolom kilas (KKK). Ekstraksi karotenoid dalam sampel minyak meliputi pencirian minyak, ekstraksi karotenoid dari sampel dibantu reaksi saponifikasi, fraksinasi karotenoid dengan KKK, pencirian karotenoid dengan kromatografi lapis tipis (KLT), spektrofotometer UV-Vis, dan kromatografi cair kinerja tinggi (KCKT). Kadar air produk sebesar 0.7% dan rendemen ekstrak 5.80% dengan total karotenoid 1110 μg/g. Hasil Uji KLT menggunakan eluen Gradien 1 (heksana:aseton 6:4 dan 7:3) dan Gradien 2 (heksana aseton 8:2 dan 9:1) menghasilkan jejak berturut-turut 3, 5, 4, dan 3 jejak. Kemudian ekstrak difraksionasi dengan KKK menggunakan sistem Gradien 1 dan Gradien 2. Identifikasi dengan spektrofotometer UV-Vis dan KCKT menunjukkan sistem Gradien 1 menghasilkan fraksi yang dominan mengandung karotena dan sistem Gradien 2 menghasilkan fraksi yang dominan mengandung kriptoxantinol

    Analysis of Hendra Virus Fusion Protein N-Terminal Transmembrane Residues

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    Hendra virus (HeV) is a zoonotic enveloped member of the family Paramyoxviridae. To successfully infect a host cell, HeV utilizes two surface glycoproteins: the attachment (G) protein to bind, and the trimeric fusion (F) protein to merge the viral envelope with the membrane of the host cell. The transmembrane (TM) region of HeV F has been shown to have roles in F protein stability and the overall trimeric association of F. Previously, alanine scanning mutagenesis has been performed on the C-terminal end of the protein, revealing the importance of β-branched residues in this region. Additionally, residues S490 and Y498 have been demonstrated to be important for F protein endocytosis, needed for the proteolytic processing of F required for fusion. To complete the analysis of the HeV F TM, we performed alanine scanning mutagenesis to explore the residues in the N-terminus of this region (residues 487–506). In addition to confirming the critical roles for S490 and Y498, we demonstrate that mutations at residues M491 and L492 alter F protein function, suggesting a role for these residues in the fusion process

    Pengaruh Sosialisasi Politik Komisi Pemilihan Umum Kota Pematangsiantar terhadap Minat Kelompok Pemilih pada Pemilu Legislatif 2014

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    This study entitled Effect of Political Socialization Election Commission Pematangsiantar Against the Interests Group of Voters In legislative elections in 2014. The aim of this study is to Know the form - the form of socialization conducted Pematangsiantar Election Commission on Legislative Election 2014; Knowing the communication channels used Election Commission Pematangsiantar for socialization Legislative Election, 2014; Knowing the factors - factors that affect the interests of the voters in the 2014 Legislative Election in Pematangsiantar; Knowing the influence of socialization and media space Election Commission elections Pematangsiantar against voter interest Legislative Election 2014. The method used in this study is the correlation method. The population in this study is that participants socialization conducted by the electoral commission Pematangsiantar city. The population in this research were 615 respondents. The sampling technique this study using techniques slovin. The sample in this study amounted to 86 respondents. This research data collection techniques using the questionnaire technique. Results of this study indicate the forms of socialization conducted Pematangsiantar city election commission on Legislative Election 2014 is to use the communication method of communication used kelompok.Saluran electoral commission Pematangsiantar city for the 2014 legislative elections socialization is the direct communication channels (face-to-face ). Factors that affect the interests of the voters in the 2014 legislative elections in the city Pematangsiantar is a style that is used in the socialization, the frequency of respondents in the general election after receiving a message socialization process and the time taken in delivering electoral commission socialization materialsPenelitian ini berjudul Pengaruh Sosialisasi Politik Komisi Pemilihan Umum Kota Pematangsiantar Terhadap Minat Kelompok Pemilih Pada Pemilu Legislatif 2014. Tujuan dari penelitian ini adalah untuk Mengetahui bentuk – bentuk sosialisasi yang dilakukan Komisi Pemilihan Umum Kota Pematangsiantar pada Pemilihan Umum Legislatif 2014; Mengetahui saluran komunikasi yang digunakan Komisi Pemilihan Umum Kota Pematangsiantar untuk sosialisasi Pemilihan Umum Legislatif 2014; Mengetahui faktor – faktor yang mempengaruhi minat pemilih pada Pemilihan Umum Legislatif 2014 di Kota Pematangsiantar; dan Mengetahui pengaruh sosialisasi media ruang pemilu Komisi Pemilihan Umum Kota Pematangsiantar terhadap minat pemilih Pemilihan Umum Legislatif tahun 2014. Metode penelitian yang digunakan dalam penelitian ini adalah metode korelasional. Populasi dalam penelitian ini adalah peserta sosialisasi yang dilakukan oleh komisi pemilihan umum kota Pematangsiantar. Populasi dalam penelitian ini berjumlah 615 responden. Teknik penarikan sampel penelitian ini menggunakan teknik slovin. Sampel dalam penelitian ini berjumlah 86 responden. Teknik pengumpulan data penelitian ini menggunakan teknik kuesioner. Hasil penelitian ini menunjukkan bentuk–bentuk sosialisasi yang dilakukan komisi pemilihan umum kota Pematangsiantar pada Pemilihan Umum Legislatif 2014 adalah dengan menggunakan metode komunikasi kelompok.Saluran komunikasi yang digunakan komisi pemilihan umum kota Pematangsiantar untuk sosialisasi pemilihan umum legislatif 2014 adalah dengan saluran komunikasi langsung (tatap muka). Faktor–faktor yang mempengaruhi minat pemilih pada pemilihan umum legislatif 2014 di kota Pematangsiantar adalah gaya bahasa yang digunakan dalam sosialisasi, frekuensi responden dalam menerima pesan pemilihan umum setelah proses sosialisasi dan waktu yang dibutuhkan komisi pemilihan umum dalam menyampaikan materi sosialisasi.147 HalamanTesis Magiste

    RETRACTION: Analisis Fungsi Harian Serambi Indonesia pada Masyarakat Desa Doy Kecamatan Ulee Kareng Kota Banda Aceh

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    RETRACTION TO:Jailani, A., Hendra, Y., &amp; Priadi, R. (2020). RETRACTION: Analisis Fungsi Harian Serambi Indonesia pada Masyarakat Desa Doy Kecamatan Ulee Kareng Kota Banda Aceh. JURNAL SIMBOLIKA: Research and Learning in Communication Study, 6(2), 96-106. doi:https://doi.org/10.31289/simbollika.v6i2.3635This article has been retracted by the publisher based on the following reason:This is based on the editor that the author has committed acts of violation of publication ethics. The author has published a triple publication by submitting the same article to one journals before and one journal after. The author admits that he forgot to have submitted the same article to another journal. This article also has published in the1. Jurnal Ilmiah Komunikasi CommuniqueJAILANI, A., Hendra, Y., &amp; Priyadi, R. (2020). Analisis Implementasi Fungsi Media Massa Pada Harian Serambi Indonesia. Jurnal Ilmiah Komunikasi Communique, 2(2), 85-93. Retrieved from http://ejurnal.stikpmedan.ac.id/index.php/JIKQ/article/view/282. PERSEPSI: Communication Journal, Vol .3 No. 2, 2020, 103-112, DOI: 10.30596/persepsi.v%vi%i.4447(Analisis Fungsi Harian Serambi Indonesia Pada Masyarakat Desa Doy Kecamatan Ulee Kareng Kota Banda Aceh | Jailani | Persepsi: Communication Journal (umsu.ac.id)One of the conditions of submission of a paper for publication in this journal is that authors declare explicitly that their work is original and has not appeared in a publication elsewhere, and also not considered by another journal. As such this article represents a severe abuse of the scientific publishing system. The scientific community takes a very strong view on this matter, and apologies are offered to readers of the journal that this was not detected during the submission dan publication process

    RETRACTION: Analisis Fungsi Harian Serambi Indonesia pada Masyarakat Desa Doy Kecamatan Ulee Kareng Kota Banda Aceh

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    RETRACTION TO:Jailani, A., Hendra, Y., &amp; Priadi, R. (2020). RETRACTION: Analisis Fungsi Harian Serambi Indonesia pada Masyarakat Desa Doy Kecamatan Ulee Kareng Kota Banda Aceh. JURNAL SIMBOLIKA: Research and Learning in Communication Study, 6(2), 96-106. doi:https://doi.org/10.31289/simbollika.v6i2.3635This article has been retracted by the publisher based on the following reason:This is based on the editor that the author has committed acts of violation of publication ethics. The author has published a triple publication by submitting the same article to one journals before and one journal after. The author admits that he forgot to have submitted the same article to another journal. This article also has published in the1. Jurnal Ilmiah Komunikasi CommuniqueJAILANI, A., Hendra, Y., &amp; Priyadi, R. (2020). Analisis Implementasi Fungsi Media Massa Pada Harian Serambi Indonesia. Jurnal Ilmiah Komunikasi Communique, 2(2), 85-93. Retrieved from http://ejurnal.stikpmedan.ac.id/index.php/JIKQ/article/view/282. PERSEPSI: Communication Journal, Vol .3 No. 2, 2020, 103-112, DOI: 10.30596/persepsi.v%vi%i.4447(Analisis Fungsi Harian Serambi Indonesia Pada Masyarakat Desa Doy Kecamatan Ulee Kareng Kota Banda Aceh | Jailani | Persepsi: Communication Journal (umsu.ac.id)One of the conditions of submission of a paper for publication in this journal is that authors declare explicitly that their work is original and has not appeared in a publication elsewhere, and also not considered by another journal. As such this article represents a severe abuse of the scientific publishing system. The scientific community takes a very strong view on this matter, and apologies are offered to readers of the journal that this was not detected during the submission dan publication process

    Kecamatan Strategies in Increasing Community Participation and Quality of Development Planning Deliberations at the Village Level of Pancur Batu District

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    Penelitian ini berjudul “Strategi Kecamatan Dalam Meningkatkan Partisipasi Masyarakat dan Kualitas Musyawarah Perencanaan Pembangunan di Tingkat Desa Kecamatan Pancur Batu”. Partisipasi masyarakat merupakan modal utama dalam upaya mencapai sasaran program pemerintah diseluruh wilayah Republik Indonesia. Keberhasilan dalam pencapaian sasaran pelaksanaan program pembangunan bukan semata-mata didasarkan pada kemampuan aparatur pemerintah, tetapi juga berkaitan dengan upaya mewujudkan kemampuan dan keamanan masyarakat untuk berpartisipasi dalam pelaksanaan program pembangunan. Adapun rumusan masalah dari penelitian ini adalah : “Bagaimana strategi kecamatan dalam meningkatkan partisipasi masyarakat dan kualitas musyawarah perencanaan pembangunan”. Metode yang di gunakan dalam penelitian ini adalah metode kualitatif yaitu penelitian tentang riset yang bersifat deskriptif dan cenderung menggunakan analisis. Rencana dan strategi kecamatan dalam peningkatan partisipasi masyarakat di bidang pembangunan dapat dilihat melalui Rencana kerja dan isu strategis yang terdiri dari pembangunan ekonomi, kemiskinan, kesehatan, pendidikan, peningkatan kapasitas aparatur dan infrastruktur wilaya

    Popularity, media and electability: study of Alfiansyah Komeng in the election of members of the Regional Representative Council (DPD) in West Java / Hendra, Mudiyati Rahmatunnisa and Ratnia Solihah

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    In 2024 Indonesia will again hold general elections to fill executive and legislative positions. One of the legislative member elections was to elect members of the Regional Representative Council (DPD) as the institution representing each province in Indonesia. An interesting phenomenon in this election was Alfiansyah Komeng's election as a DPD member representing West Java Province, surpassing the other candidates with the highest vote acquisition of 5,399,699 votes. Using a qualitative approach and data collection techniques through literature studies, the results showed that Komeng's electability was based on popularity, integrity, people's dissatisfaction with conventional politics, photos on ballot papers and the benefits of holding elections simultaneously. Meanwhile, according to the author, the media and the message conveyed are minor factors in Komeng's choice

    Biological Activities and Flavonoid Content of Different Parts of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts

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    Phaleria macrocarpa (Scheff.) Boerl (Family Thymelaceae) posses several bioactivities and is used as traditional medicine in Indonesia. Investigation on antioxidant, anti-inflammatory and antimicrobial activities are still lacking. The aims of this study were therefore to determine those biological activities of methanolic, ethyl acetate, hexane and hot water extract from pericarp, mesocarp, and seed of P. macrocarpa fruit and quantitative analysis of total phenolics and flavonoids present in the various bioactive extracts. The methanolic, ethyl acetate and hexane extracts of pericarp showed free radical scavenging activity (71.9±1.9, 88.1 ± 2.5 and 78.2± 1.7%) at concentration of 300 μg/ml and these results were lower as compared to butylated hydroxytoluene (BHT), ascorbic acid and α-tocopherol (antioxidant standards). The methanolic, ethyl acetate and hot water extracts of pericarp showed high reducing power with values 92.5±0.1, 84.7±0.3 and 91.9±0.1%, respectively at 300 μg/ml. All parts of P. macrocarpa fruit showed low to moderate level of nitric oxide inhibitory activity in IFN-γ/LPS activated RAW 264.7 cell line with values of 15.6±1.0% to 75.0±0.7% at concentration of 200 μg/ml without cytotoxic to the cells. In addition, methanol and ethyl acetate extract of P. macrocarpa fruits at 1.5 and 3 mg/disc showed variable inhibitory activity against both Gram-positive and Gram-negative bacteria with inhibition zone diameters ranging from 0.32-2.33 cm exclusive of paper disc (0.6 cm). While, ethyl acetate extract of P. macrocarpa fruits at 3 mg/well showed variable inhibitory activity against all fungi tested with inhibition zone diameters ranging from 0.4-2.13 cm exclusive of well diameter (0.6 cm). The total phenolic contents analysis showed that ethyl acetate extract of seed contained the highest amount of total phenolic at 60.94±0.81 mg GAE/g DW while the lowest amount was observed in hexane extract of pericarp at 32.97±0.69 mg GAE/g DW. Furthermore, methanolic extract of pericarp contained the highest amount of total flavonoids with a value of 161.35±1.59 mg rutin equivalent/g DW and the lowest was observed in hexane extract of seed with a value of 9.66±0.07 mg rutin equivalent/g DW. Quantitative analysis of flavonoid compounds from P. macrocarpa fruit (pericarp, mesocarp and seed) were performed by using reversed-phase high performance liquid chromatography (RP-HPLC) technique. The results showed that kaempferol, myricetin, naringin, quercetin and rutin were present in all different part of P. macrocarpa fruit. Thus, the present results showed that P. macrocarpa fruit (pericarp, mesocarp and seed) poses antioxidant, anti-inflammatory and antimicrobial activities might be due to the present of flavonoid and phenolic compounds
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