64,547 research outputs found

    The role of Plasmodium falciparum var genes in malaria in pregnancy

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    Sequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected erythrocytes binding to host receptors in the placenta such as chondroitin sulphate A (CSA). Identification of the parasite ligand(s) responsible for placental adhesion could lead to the development of a vaccine to induce antibodies to prevent placental sequestration. Such a vaccine would reduce the maternal anaemia and infant deaths that are associated with malaria in pregnancy. Current research indicates that the parasite ligands mediating placental adhesion may be members of the P. falciparum variant surface antigen family PfEMP1, encoded by var genes. Two relatively well-conserved subfamilies of var genes have been implicated in placental adhesion, however, their role remains controversial. This review examines the evidence for and against the involvement of var genes in placental adhesion, and considers whether the most appropriate vaccine candidates have yet been identified

    Marylee Meredith posing with a golf club

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    A photo of Marylee Meredith, a Pacific University student from Spokane, Washington, posing with a golf club.[back] Marylee Meredith - Spokan, Wash., Property of C. P. Rowe, P. U. Stinker 5

    Moyle, John Rowe-Residence P.1

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    26524 Preservation. John Rowe Moyle home and Indian tower, Alpine, Utah, Utah County, c. 1912 prior to house expansion

    Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV

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    The prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region

    Supplemental_Material – Supplemental material for Geographic Variance in Maryland’s Potentially Preventable Emergency Visits: Comparison of Explanatory Models

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    Supplemental material, Supplemental_Material for Geographic Variance in Maryland’s Potentially Preventable Emergency Visits: Comparison of Explanatory Models by Gina C. Rowe in Western Journal of Nursing Research</p

    Data for Clarkson, Dwyer, Flecknell, Leach and Rowe, 'Handling method alters the hedonic value of reward in laboratory mice'

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    &lt;p&gt;Raw data files for the paper &#39;Handling method alters the hedonic value of reward in laboratory mice&#39; by Jasmine M Clarkson, Dominic M Dwyer, Paul A Flecknell, Matthew C Leach and Candy Rowe.&lt;/p&gt;This work was funded by a BBSRC DTP studentship grant (BB/J014516/1)

    Behaviour of buried pipelines subjected to external loading.

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    The research presented in this Thesis was carried out at the University of Sheffield under the supervision of Dr I. C. Pyrah and Dr W. F. Anderson, and Mr G. Leach at British Gas Engineering Research Station (ERS). The research was financially supported by a British Gas Research Scholarship and by the Overseas Research Students Awards Scheme. The Author would like to express his sincere gratitude to his supervisors for their invaluable help, guidance and encouragement during the development of the research. The Author is also grateful to Dr S. R. Mi for his interest and assistance throughout the research. Special thanks also go to Dr S. J. Wheeler for his supervision during the first year of the research and sound advice in the initial stage of the work. The Author would like to express his gratitude to all members of the geotechnics group at the University of Sheffield for the useful discussions and comments. Special thanks and appreciation are extended to the staff at the ERS, particularly Mr E. Middleton for providing the data of the field tests and constructive comments. The laboratory tests were performed at ERS Soils Laboratory for which the Author is thankful to the laboratory staff. The Author must also thank British Gas for providing the computer hardware and software for performing the numerical analyses, and the printing facilities to produce the Thesis. Thanks also go to Mr D. Reay and Mr B. Bellwood at the Gas Research Centre of British Gas for ensuring continuous financial support throughout the award period. Finally, the Author wishes to thank his family and friends for their endless support and encouragement throughout the period of study in the UK. Without them, this Thesis may never have been completed

    Multimedia Systems by Neil C. Rowe

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    Invited chapter for the Encyclopedia of Distributed Computing, eds. J. Urban and P. Dasgupta, submitted 1/98, but Encyclopedia was never published.Multimedia systems combine the digital form of images, graphics, audio, electronic signals, or video with traditional text data. Multimedia systems provide many fruitful applications for distributed and parallel processing for several reasons. First, multimedia data can be bulky: A traditional television picture has almost a million bytes of data, and video needs at least 24 of those per second. Thus even simple operations on data can significantly benefit from smarter processing methods. Second, many important multimedia applications like video delivery have difficult real-time constraints. Third, multimedia data is often easily partitionable for processing.Approved for public release; distribution is unlimited

    Image Processing by Neil C. Rowe

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    Invited chapter for the Encyclopedia of Distributed Computing, eds. J. Urban and P. Dasgupta, submitted 4/00, but Encyclopedia was never published.Image processing includes a diverse set of methods for manipulation of digital images [1, 4, 5]. These include modification and enhancement (as by increasing the contrast or changing the image shape) and analysis (as by counting desired objects within the image). Digital images can be thought of as two-dimensional arrays whose entries or "pixels" represent degrees of brightness (or red, green, and blue brightnesses if a color image) at evenly spaced locations. Image processing is distinguished from computer graphics in its predominant emphasis on images originally produced by cameras and in a goal of analysis rather than synthesis of images.Approved for public release; distribution is unlimited
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