1,720,960 research outputs found
IDENTIFICATION OF ACTIVE COMPOUNDS AND FORMULATION AS AN ANTISEPTIC MOUTHWASH FROM THE PLANT Cassia fistula L. AS A PREVENTIVE MEASURE AGAINST DENTAL AND ORAL DISEASES CAUSED BY THE BACTERIA Enterococcus faecalis
Full text linkA compound with the molecular formula C15H24O has been identified as Caryophyllenol-II through analysis using HR-TOF-MS, IR, and NMR spectroscopy. The ¹³C-NMR spectrum indicates that this compound is a bicyclic sesquiterpenoid, characterized mainly by the presence of a hydroxyl group replacing an epoxide ring and the addition of an olefinic bond. The relationship between the compounds analyzed from Cassia fistula L. and their antibacterial activity against Enterococcus faecalis can be explained through the identification of bioactive compounds with specific mechanisms to inhibit or kill the bacteria. Compounds from Cassia fistula L. have significant potential as an antibacterial agent against Enterococcus faecalis, particularly through membrane disruption and bacterial enzyme inhibition mechanisms. Further research on their role, either individually or in combination with other compounds, could support the development of C. fistula-based antiseptic products, such as mouthwash, for the prevention and treatment of oral and dental diseases. Additionally, this research explores the antibacterial potential of Cassia fistula L. in developing an antiseptic mouthwash. Extracts from Cassia fistula L. are known to contain active compounds such as flavonoids, alkaloids, and tannins, which demonstrate effectiveness against Enterococcus faecalis, as a primary cause of dental and oral infections. The mouthwash formulation based on this extract was tested in vitro and proposed as a natural and safer alternative compared to synthetic chemical-based products for the prevention of dental and oral infections. This study indicates the significant potential of Cassia fistula L. in supporting oral health through effective antiseptic products. These findings support the use of traditional medicinal plants like Cassia fistula L. as a source of active compounds for the development of effective natural antiseptics and have the potential to reduce dependence on synthetic antiseptics while also promoting economic empowerment through simple industries
ISOLATION OF LIMONOIDS FROM CLAUSENA EXCAVATA BURM.F AND THEIR ANTIBACTERIAL ACTIVITY AGAINST Enterococcus faecalis
Full text linkThis study aims to isolate and characterize limonoid compounds from Clausena excavata Burm.F and evaluate their antibacterial potential against Enterococcus faecalis, a pathogen associated with antibiotic resistance in healthcare settings. Plant samples were collected from natural habitats in Southeast Asia and identified by botanists for authenticity. The leaves, stems, and fruits were dried, ground into fine powder, and subjected to ethanol/methanol maceration, followed by liquid-liquid fractionation. Column chromatography and Thin Layer Chromatography (TLC) were used for initial compound separation, while High-Performance Liquid Chromatography (HPLC) was employed for further purification. Structural characterization was conducted using Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS), and Fourier Transform Infrared Spectroscopy (FTIR). The antibacterial activity of the isolated limonoids was tested against E. faecalis using the disk diffusion method, with Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) determined through broth microdilution assays. The results indicate that limonoid compounds from Clausena excavata exhibit moderate antibacterial activity, producing inhibition zones smaller than standard antibiotics but still demonstrating potential for bacterial growth suppression. This study highlights Clausena excavata as a promising natural source of antibacterial agents, contributing to alternative solutions against antibiotic-resistant bacteria. The findings support further exploration of limonoids as lead compounds for novel antimicrobial drugs, promoting the use of natural products in combating antibiotic resistance and advancing phytopharmaceutical applications in healthcare
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Development of Educational Game-Based Learning Media for Android Using Wordwall in Chemistry Learning Acid Base Material in Class XI of SMA N 2 Muaro Jambi
Full text linkThe focus of this study is to create educational media through Android games centered on acidbase concepts, utilizing Wordwall. Additionally, the research seeks to assess the validity, practicality, and effectiveness of this educational media, as evaluated by content and media specialists, teacher feedback, student reactions, and examinations of the students' learning results related to the games created. The development framework employed follows the model proposed by Lee & Owens (2004), which consists of five phases: analysis, design, development, implementation, and evaluation. The study was carried out with a pilot group of 10 students from SMAN 2 Muaro Jambi. To analyze the data, both qualitative and quantitative approaches were used. The findings revealed that the educational game created was deemed valid and appropriate, achieving average validation scores of 4. 14 for material and 4 for media. The average evaluation score from practitioners was 4. 66. Results from the individual trials showed a success rate of 91. 11%, while the small group trial results achieved a percentage of 89. 86%. Furthermore, the effectiveness test of the product produced an Ngain of 0. 52, indicating a medium rating. From these outcomes, the Android game created with Wordwall was confirmed to be valid, practical, and effective, receiving favorable feedback from students during the learning process
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
- …
