3,499 research outputs found
Lo sviluppo della consulenza etica nei processi di HTA: i dati preliminari dell'esperienza dell'Istituto di Bioetica dell'Università Cattolica del Sacro Cuore (Roma)
No full textTitolo: Lo sviluppo della consulenza etica nei processi di HTA: i dati preliminari dell'esperienza dell'Istituto di Bioetica dell'Università Cattolica del Sacro Cuore, Roma.
Autori: SACCHINI D*, REFOLO P*, MINACORI R*, DI PIETRO ML*, RICCIARDI G**, LA TORRE G***, CICCHETTI A§, MARCHETTI M§§, AND SPAGNOLO AG*
Affiliazioni: * Istituto di Bioetica, Università Cattolica del Sacro Cuore (UCSC), Roma; ** Istituto di Igiene, UCSC, Roma; *** Dipartimento di Medicina Sperimentale, Sezione di Igiene, Università di Roma "Sapienza" ; § Facoltà di Economia, UCSC, Roma; §§ Unità di Valutazione delle Tecnologie sanitarie, Policlinico Universitario "A. Gemelli", Roma
Testo
La valutazione etica in un rapporto di Health Technology Assessment (HTA) concerne sia le questioni etiche sollevate dalla stessa tecnologia sia le questioni etiche che riguardano il processo di HTA. Anche se elencata come uno degli obiettivi dell’HTA, in pratica l'integrazione di questa dimensione in un report di HTA è stata, in passato, limitata.
Nel contesto italiano, già caratterizzato da un certo ritardo nella diffusione della HTA in generale, l'Istituto di Bioetica dell'Università Cattolica del Sacro Cuore (UCSC), Roma, Italia, dal 2007 ha cercato di colmare - dal rispettivo punto di vista disciplinare - questa lacuna, cominciando a integrare le analisi etiche in report di HTA in una attività consulenziale, sulla scia di esperienze internazionali : in particolare nel Progetto EunetHTA (2006-2008) ed ,attualmente, nell’EUnetHTA Joint Action (2010-2012).
Il contributo intende mostrare i risultati preliminari dell’applicazione dell’expertise etico in diversi rapporti di HTA nel periodo 2007-2010. I seguenti elementi saranno presentati: 1. per descrivere le metodologie / procedure utilizzate per incorporare le analisi etiche in report di HTA; 2. per rivedere l'insieme delle questioni etiche trattate; 3. per visualizzare tutte le risorse coinvolte, 4. Analizzare, infine, le difficoltà sorte nella valutazione.
In conclusione, la prospettiva è quella di strutturare e consolidare procedure operative standard (SOPs) per la consulenza etica in un processo di HTA all’interno di un servizio consulenziale facente capo all’Istituto di Bioetica dell'UCSC
Maria Bersani
No full textLa voce illustra la biografia e l'apporto letterario dato da Maria Bersani alla letteratura per l'infanziaThe headword explains the biography and the contribution of the author Maria Bersani to the children's literatur
The ethical assessment in HTA reports: the development and the evolution of the ethics consultation by Institute of Bioethics of the Università Cattolica del Sacro Cuore, Rome (Italy)
No full textThe ethical assessment in HTA reports: the development and the evolution of the ethics consultation by Institute of Bioethics of the Università Cattolica del Sacro Cuore, Rome (Italy)
The ethical assessment in an HTA report concerns both the ethical issues raised by the technology itself and the ethical issues that are related to the HTA process. Even though it is listed as one of the objectives of HTA, in practice the integration of this dimension into HTA reports has been often limited.
In the Italian context, already characterized by a certain delay in the diffusion of HTA, the Institute of Bioethics of the Università Cattolica del Sacro Cuore (Rome, Italy) tried from 2007 to fill this gap, beginning to integrate ethical analyses into HTA reports in an activity of consulting for third parties.
The contribution intends to show the results of the ethics consultation in various HTA reports from 2007 to 2010. The following elements will be presented: 1. to describe the methodologies/procedures used to incorporate ethical analyses into HTA reports; 2. to review the set of ethical questions dealt with; 3. to show the resources involved; 4. to analyse the difficulties arose in the assessment.
Finally, the perspective is to set up an HTA ethics consultation within a broad ethics consultation service by Institute of Bioethics of UCSC
Molecular mechanisms of hepatitis C virus–induced hepatocellular carcinoma
No full textAbstractHepatitis C virus (HCV) is a major leading cause of hepatocellular carcinoma (HCC). HCV-induced hepatocarcinogenesis is a multistep process resulting from a combination of pathway alterations that are either caused directly by viral factors or immune mediated as a consequence of a chronic state of inflammation. Host genetic variation is now emerging as an additional element that contribute to increase the risk of developing HCC. The advent of direct-acting antiviral agents foresees a rapid decline of HCC rate in HCV patients. However, a full understanding of the HCV-mediated tumourigenic process is required to elucidate if pro-oncogenic signatures may persist after virus clearance, and to identify novel tools for HCC prevention and therapy. In this review, we summarize the current knowledge of the molecular mechanisms responsible for HCV-induced hepatocarcinogenesis
O curso de licenciatura em educação física da Universidade Federal de Santa Catarina: suas concepções de ensino e de educação física
No full textDissertação (mestrado) - Universidade Federal de Santa Maria. Centro de Educação Fisica e Desporto
Premessa a Per d’Arco Silvio Avalle, «Le forme del canto». Interventi di Lino Leonardi, Pietro G. Beltrami, Maria Sofia Lannutti, Arnaldo Soldani
No full textThis collection of essays on medieval poetic metres, edited by Maria Sofia Lannutti following the arrangement conceived by its author, confirms the importance of d'Arco Silvio Avalle's metrical studies. Key issues are the relationship between metrical structure and music in the texts dating back to the origin of romance literatures, the multi-perspective complexity of the approach, and the exemplarity of the methodology used. © 2019 Societa Editrice il Mulino. All rights reserved
Platelet extracts induce growth, migration and invasion in human hepatocellular carcinoma in vitro
No full textImagens de Otto Maria Carpeaux: esboço de biografia
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Programa de Pós-Graduação em História, Florianópolis, 2015.Este esboço de biografia procura citar algumas imagens de Otto Maria Carpeaux: construções biográficas de naturezas múltiplas, elaboradas em contextos, por atores e sob condições igualmente díspares. Está constituído a partir de uma visão crítica da História, o que permite que ?outras imagens?, fragmentárias e não monumentais, também tenham espaço. Em diálogo com o princípio da montagem, este esboço apresenta-se em duas partes. Na primeira, Imagens possíveis, estão citadas as imagens elaboradas em vida e post mortem acerca do austríaco-brasileiro que nasceu em Viena em 1900, se exilou no Brasil em 1939 e morreu no Rio de Janeiro, em 1978. Na segunda, Montagens possíveis, apresentam-se duas possibilidades de exercício biográfico: pela leitura alegórica do documentário O velho e o Novo (Otto Maria Carpeaux), entendido como instrumento de intervenção no contexto ditatorial brasileiro e de uma reelaboração biográfica concernentes às suas experiências europeias; e pelo Caderno de imagens críticas, registro dos encontros em Carpeaux pelo meio de imagens críticas produzidas a partir da cesura do presente.Abstract : This biographical sketch attempts to quote some images of Otto Maria Carpeaux: various types of biographical constructions, carried out in different contexts by disparate authors under conditions just as distinct. It stems from a critical view of history, allowing for ?other images? fragmented and non-monumental ? to share the space.In dialogue with the montage principle, this sketch has two parts. The first, Possible Images, quotes the images produced during and after the life of the Austrian-Brazilian, who was born in Vienna in 1900, went to Brazil in exile in 1939 and died in Rio de Janeiro in 1978. The second part, Possible Montages, presents two possibilities of a biographical exercise: through the allegorical reading of documentary O Velho e o Novo (Otto Maria Carpeaux), understood as an instrument of intervention in the Brazilian dictatorship context and as a biographical retelling of the author?s European experiences; and through my Scrapbook of Critical Images, a record of the encounters in Carpeaux through critical images produced from the caesura of the present
Oral History Interview with Maria Landowska, December 21, 1989
No full textInterview with Maria Landowska, a Holocaust survivor from Metz, France. Landowska discusses family, her upbringing, her Jewish father being taken away by strangers, Kristallnacht (Chrystal Night/Night of Broken Glass), deportation by train to Dachau concentration camp, her shock and trauma, work at the camps, Auschwitz, being experimented on along with her twin, eventual recuperation, and her career as an advisor and author
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Oral History Interview with Maria Landowska, December 21, 1989
No full textInterview with Maria Landowska, a Holocaust survivor from Metz, France. Landowska discusses family, her upbringing, her Jewish father being taken away by strangers, Kristallnacht (Chrystal Night/Night of Broken Glass), deportation by train to Dachau concentration camp, her shock and trauma, work at the camps, Auschwitz, being experimented on along with her twin, eventual recuperation, and her career as an advisor and author
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