1,673 research outputs found
On the Principle and Value of Test Signaling (“Pinging”) in Pain Pathways: A Part of an Overarching Principle in Psychophysical Phenomena?
No full textRobert B Raffa,1 Wolfgang Fink2 1Temple University (Emeritus), Philadelphia, PA, USA, and University of Arizona (Adjunct), Tucson, AZ, USA; 2Visual and Autonomous Exploration Systems Research Laboratory, University of Arizona, Tucson, AZ, USACorrespondence: Robert B Raffa, Email [email protected]
On Including Pain as an Integral Part of the Fight-or-Flight Response
No full textRobert B Raffa,1,2 Wolfgang Fink,3 Anuj D Tripathi3 1Temple University (Emeritus), Philadelphia, PA, USA; 2University of Arizona (Adjunct), Tucson, AZ, USA; 3Visual and Autonomous Exploration Systems Research Laboratory, University of Arizona, Tucson, AZ, USACorrespondence: Robert B Raffa, Email [email protected]
Liquid structure of Rb-Hg alloys studied by neutron diffraction
No full textThe structures of liquid Rb–Hg alloys were studied as a function of composition by neutron diffraction. In the intermediate Rb concentration range, the obtained structure factors show a small prepeak, which may be an evidence of the formation of Hg polyanion units in liquids. The Reverse Monte Carlo (RMC) analysis was applied to separate the total radial distribution function into the corresponding partial radial distribution functions. Up to 10 at.% Rb, no obvious changes are found for the first peak position of the partial radial distribution functions of the Hg–Hg pair and that of the Hg–Rb pair. The first peak position between the Hg–Rb pairs increases above 20 at.% Rb. In addition to the first peak, a subpeak between Hg–Hg pairs can be seen in the large distance. At 60 at.% Rb, the nearest neighbor distance between Hg atoms shows the closest value in the concentration range studied. These results indicate that with the progress of charge transfer the solvation structure in the dilute Rb concentration range changes into the structure containing polyanions composed of Hg species
Fractional Edge Cover Number of Model RB
No full textModel RB is a random constraint satisfaction problem with a growing domain size, which exhibits exact phase transition phenomena. Many hard instances with planted solutions can be generated via Model RB, to be used as benchmarks for algorithmic competitions and researches. In the past, some structural parameters of constraint hypergraphs are analyzed to show hardness of Model RB, such as hinge width, decycling number, treewidth, and hypertree width. In this paper, one more structural parameter of constraint hypergraphs of Model RB, namely the fractional edge cover number, is analyzed. We show upper and lower bounds on the fractional edge cover number of Model RB. In particular, the fractional edge cover number of Model RB is shown to be asymptotically linear in the number of variables, like hinge width, decycling number, treewidth and hypertree width. These results together provide further evidences on the hardness of Model RB.EICPCI-S(ISTP)[email protected]
The unsolved case of “bone-impairing analgesics”. The endocrine effects of opioids on bone metabolism
No full textThe current literature describes the possible risks for bone fracture in chronic analgesics users. There are three main hypotheses that could explain the increased risk of fracture associated with central analgesics, such as opioids: 1) the increased risk of falls caused by central nervous system effects, including sedation and dizziness; 2) reduced bone mass density caused by the direct opioid effect on osteoblasts; and 3) chronic opioid-induced hypogonadism. The impact of opioids varies by sex and among the type of opioid used (less, for example, for tapentadol and buprenorphine). Opioid-associated androgen deficiency is correlated with an increased risk of osteoporosis; thus, despite that standards have not been established for monitoring and treating opioid-induced hypogonadism or hypoadrenalism, all patients chronically taking opioids (particularly at doses ≥100 mg morphine daily) should be monitored for the early detection of hormonal impairment and low bone mass density
MILLIMETER-WAVE SPECTROSCOPY OF COLD RB ATOMS
No full textAuthor Institution: Department of Physics, University of Virginia, McCormick Road, Charlottesville, Virginia 22903Cold Rb atoms were prepared by magneto-optical trap. Millimeter-wave has been used to drive nd to (n-2)f one-photon and nd to (n-1)g () two-photon transitions. Quantum defects of f and g states of Rb were calculated. Full analyses will be presented. }
Interpretation and the Problem of the Intention of the Author, by Burhanetir Tatar
No full textBurhanetir Tatar, Interpretation and the Problem of the Intention of the Author: H.G. Gadamer vs E.D. Hirsh, The Council for Research in Values and Philosophy, 199
Aneuploidy in spermatids of Robertsonian (Rb) chromosome heterozygous mice
No full text© 2014, The Author(s). Rb translocations are chromosomal rearrangements frequently found in natural populations of the house mouse Mus musculus domesticus. The standard diploid karyotype of the house mouse consisting of 40 telocentric chromosomes may be reduced by the emergence of metacentric Rb chromosomes. Multiple simple Rb heterozygotes form trivalents exhibiting higher anaphase nondisjunction frequency and consequently higher number of unbalanced gametes than in normal males. This work will attempt to establish whether frequencies of aneuploidy observed in heterozygote spermatids of the house mouse M. musculus domesticus show differences in chromosomes derived from different trivalents. Towards this goal, the number and distribution frequency of aneuploidy was assessed via FISH staining of specific chromosomes of spermatids derived from 2n = 32 individuals. Our results showed that for a given set of target chromosomes, 90 % of the gametes were balanced, resulting from alternate s
Synthesis and Characterization of Multiple-Cation Rb(MAFA)PbI3 Perovskite Single Crystals
No full textWe synthesized multiple-cation Rb(MAFA)PbI3 perovskite single crystals for the first time. The effect of Rb+ substitution was systemically investigated, and the addition of 1.5 M 5% RbI was the optimum condition to obtain high-quality Rb(MAFA)PbI3 single crystals. Lattice shrinkage occurred in the Rb(MAFA)PbI3 single crystal because of the small ionic radius of Rb+, resulting in blue-shifted absorption and photoluminescence (PL) peaks. The 1.5 M 5% RbI-added (MAFA)PbI3 single crystal showed the longest carrier lifetime of 18.35 ns, exhibiting the highest photoresponse than other crystals. We believe that this work will provide a basic insight into the mixed-cation perovskite single crystals for the future optoelectronic applications. © The Author(s) 201
TEMPERATURE DEPENDENCE OF AND (n=3-5) CLUSTER IONS
No full textAuthor Institution: Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801Competition between ionwater electrostatic interactions and waterwater hydrogen bonding allows several structural isomers of hydrated rubidium cluster ions to exist simultaneously. The cluster ion temperature plays a large role in determining which of these non-covalent interactions will dominate. Colder temperatures favor isomers with multiple hydrogen bonds while warmer temperatures favor less-structured isomers with fewer hydrogen bonds. The temperature, or internal energy, of hydrated rubidium cluster ions is controlled by varying the evaporative path available for cluster formation. If the evaporation involves loss of water molecules, the final cluster ion temperature will be in the range of . Evaporation of argon atoms generates substantially colder cluster ions with temperatures of . Infrared photodissociation spectra of are compared with \textit{(n=3-5)} spectra to illustrate entropic effects on the relative abundance of structural isomers in clusters. The identification of isomers present is aided by parallel \textit{ab initio}, RRKM-EE and thermodynamics calculations
- …
