26,423 research outputs found

    LIN-39 promotes neuronal fate specification in the Q and V5 lineage.

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    (A) The expression of lin-39 in AVM, SDQL/R, PDEL/R, and PVDL/R, indicated by the overlapping with neurotransmitter identity markers and specific fate markers (uIs115[mec-17p::TagRFP] for AVM, otIs181[dat-1p::mCh] for PDE, uIs117[lad-2p::mCh] for SDQ). (B) The expression of mab-5 in SDQL. (C) Summary of lin-39 (green) and mab-5 (cyan) expression in the descendants of Q and V5 lineages. (D) The loss of gcy-37 expression in AQR and AVM neurons in lin-39(n1760) mutants and the mispositioning of PQR in mab-5(gk670) mutants; the loss of lad-2 expression in SDQR in lin-39(n1760) mutants, the displacement of SDQL in mab-5(gk670) mutants, and the loss of lad-2 expression in both SDQs in lin-39(n1760) mab-5(e1239) mutants. The right panels show the penetrance for the loss of marker expression and cell body mispositioning. Mean ± SD for the percentage of cells showing corresponding phenotypes from three biological replicates are shown. Double asterisks indicate statistically significant difference (p Chi-square test. (E) The loss of ser-2 expression in PVD and PDE neurons and the loss of F49H12.4 expression in PVD in lin-39(n1760) and ceh-20(u843) mutants. (F) Dopaminergic marker dat-1 is normally expressed in PDE neurons in lin-39 mutants, but PDE shows axonal growth defects. The arrows indicate the termini of PDE axons. The expression of glutamatergic identity marker eat-4 and the PVD terminal selector gene mec-3 in PVD neurons in lin-39 mutants.</p

    Organic Carbon Burial in a Large, Deep Alpine Lake, Southwest China in Response to Changes in Climate, Land Use and Nutrient Supply over the Past ~100 Years

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    This dataset shows original data investigated in our study of spatiotemporal dynamics of OC burial in Lugu Lake, China. Further information can be found at: Lin, Q., Liu, E.F., Zhang, E.L., Nath, B., Bindler, R., Yuan, H.Z., Shen, J. In review. Organic Carbon Burial in a Large, Deep Alpine Lake, Southwest China in Response to Changes in Climate, Land Use and Nutrient Supply over the Past ~100 Years. Journal of Geophysical Research: Biogeosciences

    q-Differential equations for q-classical polynomials and q-Jacobi-Stirling numbers

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    We introduce, characterise and provide a combinatorial interpretation for the so-called q-Jacobi–Stirling numbers. This study is motivated by their key role in the (reciprocal) expansion of any power of a second order q-differential operator having the q-classical polynomials as eigenfunctions in terms of other even order operators, which we explicitly construct in this work. The results here obtained can be viewed as the q-version of those given by Everitt et al. and by the first author, whilst the combinatorics of this new set of numbers is a q-version of the Jacobi–Stirling numbers given by Gelineau and the second author

    Asymmetric Total Syntheses of Ansamacrolactams (+)-Q-1047H-A-A and (+)-Q-1047H-R-A

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    The total syntheses of ansamacrolactams (+)-Q-1047H-A-A (16) and (+)-Q-1047H-R-A (17) have been achieved for the first time In 17 steps, leading to the reassignment of the relative stereochemistries and absolute configurations of their natural counterparts. The key steps In the synthetic work included an asymmetric chelation-controlled vinylogous Mukaiyama aldol reaction for the stereoselective synthesis of the syn-aldol adduct 7b and an intramolecular SmI2-mediated Reformatsky reaction for the formation of the macrocyclic lactam 14.Chemistry, OrganicSCI(E)PubMed4ARTICLE4812-8151

    Estudo variacional do modelo de Moszkowski-q-deformado

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    Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas.A validade da utilização do método variacional via estados coerentes q-deformados e aqui testada, no contexto das álgebras quânticas, para dois diferentes tipos de modelos, o de Lipkin e o de Moszkowski. O comportamento da transição de fase sob o efeito da deformação e também observado nos dois modelos acima. Há várias maneiras diferentes de se deformar quanticamente um sistema. Nessa dissertação duas dessas maneiras são estudadas em detalhe, e suas diferenças são apontadas

    sj-docx-1-jdr-10.1177_00220345221092752 – Supplemental material for Single-Cell Transcriptomic Atlas of Gingival Mucosa in Type 2 Diabetes

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    Supplemental material, sj-docx-1-jdr-10.1177_00220345221092752 for Single-Cell Transcriptomic Atlas of Gingival Mucosa in Type 2 Diabetes by Q. Wang, W. Lin, X. Zhou, K. Lei, R. Xu, X. Zhang, Q. Xiong, R. Sheng, W. Song, W. Liu, Q. Wang and Q. Yuan in Journal of Dental Research</p

    Evolutionary programming with q-Gaussian mutation for dynamic optimization problems

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    This article is posted here with permission from IEEE - Copyright @ 2008 IEEEThe use of evolutionary programming algorithms with self-adaptation of the mutation distribution for dynamic optimization problems is investigated in this paper. In the proposed method, the q-Gaussian distribution is employed to generate new candidate solutions by mutation. A real parameter q, which defines the shape of the distribution, is encoded in the chromosome of individuals and is allowed to evolve. Algorithms with self-adapted mutation generated from isotropic and anisotropic distributions are presented. In the experimental study, the q-Gaussian mutation is compared to Gaussian and Cauchy mutation on three dynamic optimization problems.This work was supported by Brazil FAPESP under Grant 04/04289-6 and UK EPSRC under Grant No. EP/E060722/01

    Organic Carbon Burial in a Large, Deep Alpine Lake, Southwest China in Response to Changes in Climate, Land Use and Nutrient Supply over the Past ~100 Years

    No full text
    This dataset shows original data investigated in our study of spatiotemporal dynamics of OC burial in Lugu Lake, China. Further information can be found at: Lin, Q., Liu, E.F., Zhang, E.L., Nath, B., Bindler, R., Yuan, H.Z., Shen, J. In review. Organic Carbon Burial in a Large, Deep Alpine Lake, Southwest China in Response to Changes in Climate, Land Use and Nutrient Supply over the Past ~100 Years. Journal of Geophysical Research: Biogeosciences

    Fig. 1. – Primulina dongguanica F. Wen, Y. G. Wei & R. Q. Luo. A in Primulina dongguanica F. Wen, Y. G. Wei & R. Q. Luo (Gesneriaceae), a new species from South China

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    Fig. 1. – Primulina dongguanica F. Wen, Y. G. Wei & R. Q. Luo. A. Habit; B. Opened corolla with stamens and staminodes; C. One calyx lobe; D. Calyx and pistil. [Fang Wen 100803, IBK] [Drawing: Wen-Hong Lin]Published as part of Wen, Fang & Wei, Yi-Gang, 2014, Primulina dongguanica F. Wen, Y. G. Wei & R. Q. Luo (Gesneriaceae), a new species from South China, pp. 9-19 in Candollea 69 (1) on page 11, DOI: 10.15553/c2014v691a2, http://zenodo.org/record/576184

    Q(10) values vary with different kinetic properties of C mineralization

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    Temperature response quotient (Q(10)) is a critical parameter for evaluating global additional carbon (C) release with climate change. However, its value is usually derived from time span or instantaneous rate or cumulative amount of C flux, giving a very one-sided account of thermal sensitivity of C cycling. Through a 117-day laboratory incubation study, we estimated Q(10) values simultaneously with the labile (a(0)) and recalcitrant C proportions and their rate constants, and then tested for any variances of these kinetic properties in different vegetation stands, soil horizons, aeration statuses, and thermal settings (i.e., diurnally-varying, constant low and constant high temperatures). A regularly varying temperature regime increased the exploitation of labile C resources (i.e., high a0) and required longer time spans (i.e., low rate constants). The constant high temperature induced the exhaustive depletion of the labile C pool and motivated a very rapid and short-term C mineralization process. The constant low temperature treatment was characterized by the lowest a(0) but by medium rate constants because low temperature slowed the C mineralization processes but retained high level of the original C processing diversity. Therefore, a(0), and the rate constants showed discrepancies in their temperature sensitivities as revealed by pairwise comparisons of temperature regimes. Such discrepancies were also supported by pairwise comparisons of aeration statuses, forest stands and soil horizons. The Q(10) bias between C mineralization a(0) and rate constants in this laboratory experiment is attributed to the inherently distinct properties of these two parameters, as a(0) and its Q(10) are closely correlated with the sizes of the easily available C pool, while rate constants and their Q(10), variances explain the temporal scale of the same C mineralization process. Our findings suggest a combined application of a(0) and rate constants for exploring the temperature sensitivity of C mineralization in future studies
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