1,192 research outputs found
Geochemistry, isotopic composition and petrogenetic modelling of the Colli Albani volcanic rocks
No full textThe Colli Albani volcano belongs to the Roman Magmatic Province and is character-
ized by strongly silica undersaturated leucite-bearing ultrapotassic rocks. Melilite-bearing leuciti-
tic lavas, beside tephritic to tephritic phonolitic ignimbrites, were erupted during the pre-caldera
(Vulcano Laziale) period. The post-caldera phase opened with magmas erupted from different
feeding systems, with melilite-bearing leucitites in the early phases followed by tephritic and pho-
nolitic tephritic lavas. The late-stage activity (i.e. the Via dei Laghi period) is characterized by
hydromagmatic tuffs with small juvenile fragments that prevent a clear compositional definition
of the magma triggering the eruptions. Despite their mineralogical and compositional similarities,
the Vulcano Laziale period (pre-caldera) has significantly higher levels of incompatible trace
elements and 87Sr/86Sr isotopes than found in magmatic rocks erupted after the caldera formation.
Pre- and post-caldera parental magmas are considered to be significantly different from each other
and generated within a metasomatized upper mantle under different degrees of partial melting.
Crustal-derived carbonate-rich metasomatism is thought to have affected the mantle wedge of
the Italian peninsula. Melting of pelitic sediments with different amounts of CaCO3 is considered
the source of the metasomatic agents, which are able to re-fertilize the lithospheric upper mantle.
Partial melting of this modally metasomatized lithospheric mantle under high XCO
2 produced the
strongly silica undersaturated ultrapotassic magmas observed at the Colli Albani volcano. A
second-order differentiation process occurs at shallow levels, with fractional crystallization and
crustal assimilation of wall rock (AFC), locally changing the compositions of magmas and pro-
ducing several differentiation pathways that have given rise to the geochemical and petrological
complexity of the Colli Albani volcano. Assimilation of carbonate sediments and silicoclastic
sedimentary lithologies also occurred coevally, suggesting the existence of several separate
magmatic reservoirs at shallow levels, possibly at different depths and surrounded by different
sedimentary formations
Il De anima di Aristotele e la rudis expositio aliquorum: una nota sull’ “antitomismo” di fine XIII secolo
No full textIn his De visione beatifica Dietrich of Freiberg criticizes a rude interpretation which some authors (rudis expositio aliquorum) gave on Aristotle’s concept of “nobility,” concerning a passage of De anima’s book III. Since De visione is considered one of the most antithomistic writings of Dietrich of Freiberg, Thomas Aquinas and his followers are usually regarded as the main polemical objective of the German Dominican theologian. However, as he does not explicitly quote Thomas, it is plausible that the expression rudis expositio is related to a broader interpretative context. Starting from these considerations, the author proposes an innovative solution to the problem. In so doing, he introduces a new approach to categories such as “thomism” and “antithomism.
The Colli Albani mafic caldera (Roma, Italy): stratigraphy, structure and petrology
No full textNew results for the Colli Albani volcano (Roma, Italy) surveyed for the Geological Map of Italy at 1 : 50,000 scale (CARG
Project), integrated with previous data, provide insights on caldera evolution. The Colli Albani, a quiescent volcano, became
active a
Sobre a genealogia da moral de Nietzsche
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Programa de Pós-Graduação em Filosofia, Florianópolis, 2013.Na presente dissertação, dedicamo-nos à análise do trabalho realizado por Friedrich Nietzsche em sua Genealogia da Moral - Uma Polêmica, destacando a ideia de transvaloração de todos os valores apresentada em tal obra. Acompanhamos o percurso do filósofo neste escrito, desde sua investigação a respeito da origem dos pares de conceitos "bom e ruim" e "bom e mau", até sua conclusão sobre a preferência do homem por "querer o nada a nada querer". Inicialmente analisamos os conceitos morais colocados em questão por Nietzsche, até alcançarmos os ideais que os fundamentam e constatarmos que eles estão a serviço de uma saúde fraca que luta agonicamente pela vida. Em seguida, elucidamos osmotivos e os perigos de uma disseminação de tal fraqueza entre oshomens que compõem o substrato cultural analisado na obra emquestão. Por fim, refletimos sobre duas ocorrências que emergem apartir deste movimento cultural, tornando possível uma transvaloraçãodos valores que pautam a moral investigada: a autoconscientização davontade de verdade e o niilismo.Abstract : In the thesis we dedicate the analysis of the work made by Friedrich Nietzsche in his On Genealogy of Morals - A Polemic, showing the idea of transvaluation of values emphasized in the composition. Followingthe philosopher's way in this thesis, since his investigations about thebeginning of pair conceptions "good and evil" and "good and bad", untilhis conclusions about the men preferences "to want nothing instead ofnothing to want". At first we studied the moral concepts as is shown byNietzsche until we reach the ideals that substantiate them and we noticethey are in service of a weak health that struggles for life. Then, we elucidate the reasons and the dangers of the dissemination of such weakness among men who compose the cultural substratum analyzed in the composition. Finally, we realize that two occurrences emerge from this cultural movement, they make a transvaluation of values (thatcompose the investigated moral) possible: the self-awareness of a will to truth and the nihilism
La conoscenza decurtata delle substantiae nobilissimae: traduzioni e «tradimenti» nel De animalibus libri XXVI di Alberto il Grande
No full textAbstract non disponibil
The polymorphism of enzyme MTHFR in children suffering from migraine ad epilepsy
No full textThe C677T variant in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with increased levels of circulating homocysteine and is a mild risk factor for vascular disease. Mild Hcy elevation (>15 mmol L−1) in the adult population is associated with increased risk of myocardial infarction, stroke, peripheral arterial disease and venous thrombosis.[1,2,3] The MTHFR 677CT mutation is frequent in Caucasians; MTHFR mutant allele occurs commonly in 5% to 15% of the population, and the heterozygosis is over 40%. The C677T polymorphism of the MTHFR gene has been associated with different diseases such as stroke, coronary artery disease, bipolar disorder, schizophrenia and depression. Homozygosis for MTHFR 677 CT mutations is more frequent in epileptic patients compared with healthy controls (23% vs. 12%) and heterozygosis is about 52%. Lipton[1] showed that Hcy may have excitotoxicity to neurons as an agonist of the glutamate binding site of the N-methyl-Daspartate (NMDA) receptors. Migraine, with and without aura (MA and MO), is a prevalent and complex neurovascular disorder that may also be affected by genetically influenced hyperhomocysteinaemia
Aim of this study is the evaluation of incidence of mutation of enzyme MTHFR in the children suffering from two disease, epilepsy and migraine as in comorbility, as without comorbility.
MATERIALS AND METHODS
32 patients suffering from headache observed during 3 months and 34 children affected by epilepsy observed during the same time represent the sample of this study. At the first observation in day hospital are determined the homocisteinaemia levels and mutation C677 of enzyme MTHFR. In the sample is studied MR brain and EEG. In the familial history is considered the headache, the epilepsy, the stroke and cardiovascular disease. The homocisteinaemia is evaluated by immunological fluorescent method (FPIA) The mutation of enzyme C677 is studied by technique of qualititative Real-Time PCR.
RESULTS
27 patients suffering from generalized epilepsy, 7 from partial epilepsy. In the 18%of these patients there is C677 enzyme mutation and 7% show homozygous condition. Among 32 children suffering from headache, 17 have TTH, 9 MO, and 6 MA. 50% show MTHFR mutation. The allele is present in the 83% of MO and in 87% of MA and homozygosis condition is present in 22% of children. The values of homocisteinaemia are higher in the homozygous than heterozygous patients (9.48 μmol/L vs. 8.3 μmol/L) and this condition is more evident in the migraines than epileptic patients. In the 50% of the sample with C677 mutation there are MR lesions as cerebrovascular disease. 1 child shows the results of ischemic event in the foetal life. We underline the history of 2 patient’s hemiplegic suffering, one from migraine, one from epilepsy.
DISCUSSION
Kowa et al. [1] originally reported a positive association between the MTHFR C677T variant and migraine in a Japanese case control cohort. These researchers indicated an increased risk of migraine in Japanese individuals possessing the homozygous T/T genotype. Stratified analyses specifically showed that the T/T genotype was significantly over-represented in these Japanese patients with MA compared to non-migraine controls (40% vs. 9.6%), producing an OR of ~6. These positive findings were reinforced by another recent migraine case-control study conducted in a Turkish population. These researchers reported that the MTHFR C677T is associated with migraine and also indicated that the T/T genotype specifically increased risk of MA (OR ~10). It is important to note that the frequency of the MTHFR 677T allele, and indeed migraine prevalence, is known to vary substantially among different ethnic populations. Thus, this study supports the findings of other authors and shows the hypothetical role of this genetically aspects in the comorbility migraine - epilepsy.
1. BMC Medicine 2 (2004):3
2. Cephalalgia 28 (2008): 376-382
3 Eur J Radiol 2009 feb 1
Assessing The Spatial Dependence of Adaptive Loci in 43 European and Western Asian Goat Breeds Using AFLP Markers
No full textBackground: During the past decades, neutral DNA markers have been extensively employed to study demography, population genetics and structure in livestock, but less interest has been devoted to the evaluation of livestock adaptive potential through the identification of genomic regions likely to be under natural selection. Methodology/Principal findings: Landscape genomics can greatly benefit the entire livestock system through the identification of genotypes better adapted to specific or extreme environmental conditions. Therefore we analyzed 101 AFLP markers in 43 European and Western Asian goat breeds both with MATSAM software, based on a correlative approach (SAM), and with MCHEZA and BAYESCAN, two FST based software able to detect markers carrying signatures of natural selection. MATSAM identified four loci possibly under natural selection - also confirmed by FST-outlier methods - and significantly associated with environmental variables such as diurnal temperature range, frequency of precipitation, relative humidity and solar radiation. Conclusions/Significance: These results show that landscape genomics can provide useful information on the environmental factors affecting the adaptive potential of livestock living in specific climatic conditions. Besides adding conservation value to livestock genetic resources, this knowledge may lead to the development of novel molecular tools useful to preserve the adaptive potential of local breeds during genetic improvement programs, and to increase the adaptability of industrial breeds to changing environments. © 2014 Colli et a
Effect of mordants on the variation of diameter and colour tone in alpaca fibre threads dyed with colli (Buddleja coriacea) flowers
No full textThe aim of this study was to evaluate the effect of mordants on the variation of mean fibre diameter (MFD), spinning fineness (SF), and colour tone in alpaca fibre threads dyed with colli flowers (Buddleja coriacea). The dye was extracted using boiling water, followed by immersion of the thread in 160 ml of extract and post-mordanting with collpa, alum, and lemon salt at boiling temperature. MFD was measured using S-Fiber Med equipment. Colorimetry parameters were obtained using a spectrometer, and FT-IR spectrophotometer was used for identification of functional groups. MFD in colli-dyed and post-mordanted threads significantly increased with the addition of mordants, with the highest change observed with lemon salt (30.09 μm). The same trend was observed for SF. Dyeing with colli flower extract and subsequent mordant application produced different shades and hues of yellow colour in alpaca thread with significant variations in colorimetry parameters and FT-IR spectrum intensity. The reflectance spectrum R (%) showed a typical yellow colour curve with small differences in intensity due to the mordants used. In conclusion, MFD in colli-dyed thread increased by 0.44 µm; collpa mordanted by 2.78 µm; alum by 3.31 µm, and lemon salt by 3.51 µm compared to white thread, also producing different shades and hues of yellow colour with significant variations in colorimetry parameters and K/S. The sample dyed with colli without mordant presented the highest intensity, and lower intensity was observed in post-mordanted samples in FT-IR.El objetivo del estudio fue evaluar el efecto de mordientes en la variación de diámetro medio de fibra (DMF), finura al hilado (FH) y el tono de color en hilos de fibra de alpaca teñidos con flores de colli (Buddleja coriacea). El colorante fue extraído usando agua a temperatura de ebullición, seguido del teñido mediante la inmersión del hilo en 160 ml de extracto y finalizando se hizo el pos-mordentado con ccollpa, alumbre y sal de limón a temperatura de ebullición. El DMF se midió utilizando el equipo S-Fiber Med. Los parámetros de colorimetría se obtuvieron utilizando un espectrómetro y para la identificación de los grupos funcionales se utilizó el espectrofotómetro FT-IR. El DMF en hilos teñidos con colli y pos-mordentados incrementaron significativamente con la adición de mordientes, observándose el mayor cambio con sal de limón (30.09 μm). Esta misma tendencia, se presentó para la finura al hilado. El teñido y la posterior aplicación del mordiente produjo diferentes tonos y matices de color amarillo en el hilo de alpaca con variaciones significativas en los parámetros de colorimetría y la intensidad del espectro FT-IR. El espectro de reflectancia R (%) mostró una curva típica del color amarillo con pequeñas diferencias en la intensidad según los mordientes utilizados. En conclusión, el DMF en hilo teñido con colli incrementó en 0.44 µm; mordentado con ccollpa en 2.78 µm; alumbre en 3.31 µm y con sal de limón en 3.51 µm comparado con el hilo blanco; además produjo diferentes tonos y matices de color amarillo con variaciones significativas en los parámetros de colorimetría y K/S. La muestra teñida con colli sin mordiente presentó la intensidad más alta y menor intensidad en muestras pos-mordentadas en FT-IR
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