599 research outputs found
The phenomenon of Yulia Tymoshenko in politics of Ukraine
No full textYulia Tymoshenko's leadership style and leadership are analy¬zed and described in this article. The author stated that political opposition was a natural element for Tymoshenko. Her time as Prime Minister was rather controversial, hence the assessements of her successes and failures propensities to vary. A description of Tymoshenko as a political party leader that included the way she chose people to work with was also given
PENINGKATAN KEMAMPUAN MEMBACA PEMAHAMAN DENGAN MODEL PEMBELAJARAN KOOPERATIF TIPE STUDENT TEAM ACHIEVEMENT DIVISIONS (STAD) SISWA KELAS VII SMP SEMEN PADANG
No full textAbstrakKeterampilan membaca merupakan landasan yang menjadi syarat mutlak yang harus dikuasai siswa untuk menggali dan menimba ilmu pengetahuan lebih lanjut. Tanpa penguasaan yang mantap terhadap kemampuan tersebut tentu ilmu-ilmu yang lain tidak dapat dikuasai. Dalam kehidupan sehari-hari peranan membaca sangat penting. Penggunaan pembelajaran kooperatif tipe STAD dalam pembelajaran membaca pemahaman dirancang dalam bentuk Rancangan Pelaksanaan Pembelajaran (RPP) yang disusun dengan berpedoman kepada Kurikulum Tingkat Satuan Pendidikan (KTSP). Proses pembelajaran membaca pemahaman menggunakan empat tahap, yaitu presentasi kelas, belajar tim, kuis individual, dan penghargaan tim. Evaluasi hasil yang dilaksanakan, yaitu terlihat dari kemampuan anak dalam menemukan gagasan utama serta gagasan penjelas, dan membuat ringkasan. Penelitian mengungkapkan bahwa hasil tes siklus I nilai rata-rata membaca siswa adalah 72,65 dan pada siklus II nilai rata-rata membaca siswa adalah 77,26. Hasil tes menunjukkan adanya peningkatan. Dari hasil penelitian terungkap bahwa hasil evaluasi menunjukan bahwa keberhasilan guru dalam pembelajaran ditentukan oleh deskriptor yang direncanakan dengan persentase pada siklus I adalah 80 dan pada siklus II adalah 93,3Kata Kunci: Peningkatan, Membaca Pemahaman, Pembelajaran, Model Kooperatif
"Yulia" by N. M. Karamzin: the first experience of creating a high society story in Russian literature
No full textВ статье рассматривается повесть Н. М. Карамзина "Юлия" в аспекте жанра. В ходе анализа приводятся дополнительные аргументы в пользу того, что "Юлия" является первой в отечественной литературе светской повестью, давшей начало перспективной жанровой традиции.In the article N. M. Karamzin's story "Yulia" is considered in aspect of a genre. During the analysis the author of the article brings the additional arguments in favor of the fact that "Yulia" is the first "high society story" in the domestic literature. Such a story opened a perspective genre tendency for further literature
"Yulia" by N. M. Karamzin: the first experience of creating a high society story in Russian literature
No full textВ статье рассматривается повесть Н. М. Карамзина "Юлия" в аспекте жанра. В ходе анализа приводятся дополнительные аргументы в пользу того, что "Юлия" является первой в отечественной литературе светской повестью, давшей начало перспективной жанровой традиции.In the article N. M. Karamzin's story "Yulia" is considered in aspect of a genre. During the analysis the author of the article brings the additional arguments in favor of the fact that "Yulia" is the first "high society story" in the domestic literature. Such a story opened a perspective genre tendency for further literature
UPAYA-UPAYA ROOM ATTENDANT DALAM MEMELIHARA KENYAMANAN TAMU DI VASA HOTEL SURABAYA
Get PDFThe goal to be achieved in this research is to find out the efforts made by the room
attendant in maintaining guest comfort at Vasa hotel Surabaya so that guests feel
happy, satisfied and want to visit again at Vasa Hotel Surabaya. The author makes
observations of the room attendant's efforts in maintaining guest comfort. The
author concludes that the efforts made by the room attendant in maintaining guest
comfort at Vasa hotel Surabaya are as follows: Maintain cleanliness, greet guests
and offer assistance, pause and say hello when meeting guests in the corridor area
or other places other than the room. , and provides towel folding services (towel
art) and has also carried out standard operating room attendant procedures
PERUBAHAN NILAI BUDAYA MINANGKABAU DALAM NOVEL TENGGELAMNYA KAPAL VAN DER WIJCK KARYA HAMKA DAN NOVEL BULAN SUSUT KARYA ISMET FANANY (KAJIAN PERBANDINGAN)
No full textLocal culture is very diverse Indonesia became an honor and challenge to maintain and inherited to the next generation. Local Indonesian culture is very proud because it has a very varied diversity and unique. As time, lead to changes in lifestyle a more modern society. As a result, people will prefer the new culture that may be considered more practical than the local culture. Views on kinship, treasures, and wander in the novel Tenggelamnya Kapal Van Der Wijck Hamka works and novels Bulan Susut works Ismet Fanany changes and cultural shifts. Kinship, treasures, and wander in the novel Sinking Ship Van Der Wijck Hamka's work is described explicitly, whereas kinship, treasures, and wander in the novel Month Losses Ismet work Fanany described implicitly. Changes in people's lives has implications for social Minangkabau culture in Minangkabau society. A leadership that is both functional mamak transformed into symbolic leadership. Mamak originally as straps tribesmen, has changed the status and intrinsic meaning.</em
ANALISIS FIKSI KADO UNTUK PUTRI UNGU DAN SURI CUCU KAKEK DULHAK: TINJAUAN STRUKTURALISME
No full textThe Relationship between Learning Motivation and Paragraph Knowledge on the Students' Ability to Write a Short Story at SMPN 21 Padang
No full textThe roles of structural variability and amphiphilicity of TMC278/rilpivirine in mechanisms of HIV drug resistance avoidance and enhanced oral bioavailability
No full textNon-nucleoside reverse transcriptase inhibitors (NNRTIs) are small hydrophobic drug molecules that bind to a hydrophobic pocket of the HIV-1 reverse transcriptase (RT). A number of molecules from diarylpyrimidine (DAPY) class of NNRTIs have exceptional inhibitory properties against a broad range of known drug-resistant viral strains of HIV-1 and good oral bioavailability in humans. Biophysical, structural, and computational methods were applied to study DAPY NNRTIs with differing RT inhibitory and bioavailability properties with a goal to define the mechanisms by which the dual success of the selected DAPY NNRTIs is achieved.
Exceptional bioavailability properties of selected DAPY NNRTIs were hypothesized to stem from their ability to form self-formulated spherical drug aggregates, ~60 nm in diameter, that are trafficked from the gastrointestinal tract into systemic circulation through a lymphatic uptake pathway. Using dynamic light scattering (DLS) and electron microscopy (EM), formation of drug aggregates was demonstrated. Drug aggregation was determined to be surfactant independent. Based on this observation, it was hypothesized that the drug molecules were able to achieve surface-active properties. Using X-ray crystallography and all atom MD simulations of the drug aggregate/water interface it was determined that amphiphilic properties of the selected DAPY NNRTI molecules depend on the availability of the protonation site at the pyrimidine ring and structural variability of the drug molecules at the linker moieties.
Ability of the late phase DAPY NNRTI drug molecules to inhibit the broad range of drug-resistant HIV-1 mutants has been previously linked to the ability of the molecules to sample multiple binding modes within the binding pocket of HIV-1 RT (Das et al., 2004). Using computational methods, conformational sampling by TMC278 (a DAPY NNRTI in multiple Phase III trials) in the pocket of the wild-type and the mutant NNRTI-binding pocket (NNIBP) was evaluated. Results of this work support the concept that structural variability is important in overcoming drug resistance mechanisms.
We propose that the implementation of drug aggregation testing and the evaluation of torsional flexibility of highly hydrophobic compounds in the context of the lead identification strategies will allow for better selection of potent and orally bioavailable hydrophobic drug candidates.Ph.D.Includes bibliographical references (139-146)by Yulia Frenke
Correlation of mastering effective sentences and learning motivation to writing skills of explanation text for high school students
Get PDFThis article aims to describe and describe the relationship between effective sentence mastery and student motivation to write explanatory text skills. The results of data processing using multiple regression to the explanatory text writing variable (Y) resulted in a multiple regression coefficient (b) of 0.094 for effective sentence mastery (X1) and 0.791 for learning motivation (X2) and a constant (a) of 50.547. Thus, the form of the correlation between the three variables can be expressed by the multiple regression equation Ẏ = 50.547 + 0.094X1 + 0.791 X2. The results of the data obtained in the form of a correlation that has a significant value between effective sentence mastery and learning motivation on explanatory text writing skills at the coefficient of determination R2 = 0.375, effective sentence mastery and learning motivation affect explanatory text writing skills by 37.5%. </p
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