182 research outputs found
Supplementary Videos
No full textSupplementary Video S1: Examples of spheroids growth in elastic (left) and viscoelastic (right) matrices.
Supplementary Video S2: Examples of simulated tissue growth in elastic (left) and viscoelastic (right) matrices.
Supplementary Video S3: Examples of simulated tissue growth when cell motility is inhibited in elastic (left) and viscoelastic(right) matrices.
Supplementary Video S4: Examples of simulated tissue growth when cell proliferation is inhibited in elastic (left) and viscoelastic(right) matrices.
Supplementary Video S5: Examples of simulated tissue growth in elastic (upper row) and viscoelastic (lower row) in matrices of increasing stiffness.
Supplementary Video S6: Examples of simulated tissue growth when cell migration is inhibited in elastic (upper row) and viscoelastic (lower row) in matrices of increasing stiffness.
Supplementary Video S7: Examples of simulated tissue growth when cell proliferation is inhibited in elastic (upper row) and viscoelastic (lower row) in matrices of increasing stiffness.
Supplementary Video S8: Example of simulated tissue growth when cells are continuously added to the tissue in elastic (left) and viscoelastic (right) matrices.
Supplementary Video S9: Example of simulated tissue growth when the matrix property changes from elastic to viscoelastic.
Supplementary Video S10: Example of simulated tissue growth when the matrix property changes from viscoelastic to elastic.
Supplementary Video S11: Examples of simulated organoid tissue growth in elastic (upper row) and viscoelastic (lower row) in matrices of increasing stiffness.
Supplementary Video S12: Examples of simulated organoid tissue growth in viscoelastic matrices where two black cells have higher motility (M) compared to the rest (M_0).
Supplementary Video S13: Examples of simulated organoid tissue growth in viscoelastic matrices where an increasing number of cells (black) have 4 times higher motility compared to the rest.
Supplementary Video S14: Examples of simulated organoid tissue growth in viscoelastic matrices where four black cells have an increasing probability (P) to divide compared to the rest (P_0 )
Rigidity sensing and adaptation through regulation of integrin types
No full textPublished in final edited form as:
Nat Mater. 2014 June ; 13(6): 631–637. http://dx.doi.org/10.1038/nmat396
Ozeano Artikoko bankisaren beherakada: behaketak berrikusten, kausa fisikoak ulertzen eta etorkizuneko aldaketak iragartzen
No full textLaburpena: Ozeano Artikoa bankisa mehe batez estalita dago. Bankisa klima polarra taxutzen duen faktore garrantzitsuetako bat da, eta eragina izan dezake klima-sistema globalean ere. Garrantzi hori dela eta, beharrezkoa da Artikoko bankisa horren egoerari begiratzea eta hura ulertzea eta aurreikustea. Behaketek argi eta garbi erakutsi dute izotzaren hedadura eta lodiera murrizten ari direla eta izotz iraunkorra zena aldikako izotz ari dela bilakatzen. Inolako zalantza-izpirik gabe, Artikoko bankisa gainbehera nabarian dago. Bankisaren gainbehera hori ulertzeko, aldaketa horien kausa izan litezkeen prozesu termodinamiko eta dinamiko giltzarriak aztertu behar dira. Prozesuon artean daude, besteak beste, faktore fisikoak (adibidez, epeltzeko joerak), atmosferako eta ozeanoko zirkulazioan gertatutako aldaketak, ozeanoaren gainazalera iristen den eguzki-erradiazio handiagoa eta horri lotutako izotz-albedoaren berrelikadura. Gaur egungo ereduek aurreikusten dute mende hau amaitu baino lehen Ozeano Artikoa izotzik gabe geratuko dela udako urtze-garaiaren bukaeran. Behaketek, baina, erakusten dute bankisaren beherakada ez dela ereduek iragarritako abiaduran gertatzen ari, azkarrago baizik, eta agerian uzten dute ereduak hobetzeko premia. Artikoko bankisaren gainbeherak ondorio garrantzitsuak ditu Artikoko eta Lurreko klima-sistemetan, eta, gainera, gero eta erronka handiagoak ezartzen ditu alor sozioekonomikoan, politikoan eta ekologikoanThe Arctic Ocean is covered by a thin layer of sea ice. Sea ice plays an important role in determining Arctic climate, and it can also have an influence in the global climate system. This importance creates a need to observe, understand, and predict the state of the Arctic sea-ice cover. Observations unambiguously show that the ice extent is decreasing, the ice thickness is thinning, and that there is a shift from perennial ice to seasonal ice. It is beyond doubt that Arctic sea ice is in marked decline. Understanding the observed decline in sea ice involves examining the key thermodynamic and dynamic processes that can cause such changes. These include physical factors such as warming trends, shifts in atmospheric and oceanic circulation, increased solar radiation reaching the ocean surface, and the associated ice-albedo feedback. Current models predict an ice-free Arctic Ocean at the end of the Summer melt season by the end of this century, but observations reveal that the ongoing sea-ice decline is occurring more rapidly than model-based projections, highlighting the need of model improvements. A declining Arctic sea ice has important implications not only for both the Arctic and the global climate system, it also poses mounting socio-economic, political, and ecological challengesPeer Reviewe
Fikzioa J.-P. Sartreren diskurtso teorikoan: Fikzioaren antolamendua L'Être et le Néant obra filosofikoaren "Begirada" kapituluan
No full text344 p.Ikerketa honek J.-P. Sartreren L'Être et le Néant tratatu filosofikoaren idaztankeran jartzen du arreta, eta obra horren irakurketa berri bat eskaintzen du, hain zuzen ere, diskurtso teorikoak baliatzen duen fikzioaren ikuspegitik. "Begirada" kapitulu luze eta funtsezkoa ikerketa-corpustzat hartuta, eta berau euskaratuta, ikerketa honen helburua da baliabide horren eginkizun nagusia ulertzea. Xede horrek eskatzen du ikerketa honi diskurtsoaren analisiaren esparrutik heltzea, fikzioa irizpide enuntziatiboen argitan zedarritzeko eta diskurtso-antolamenduaren baitan ulertzeko. Halatan, ikerketa honek erakusten du, alde batetik, testuko fikzioa diskurtso teoriko nagusiarekiko etendura gisa enuntziatzen dela, teoria beste erregistro batean adierazteko; beste alde batetik, fikzioak adarkadura bat osatzen duela diskurtsoan, horrek parte zuzena duela diskurtsoaren antolamendu teorikoan eta, halaber, testuaren jomuga teorikoa bermatzen duela
Fikzioa J.-P. Sartreren diskurtso teorikoan: Fikzioaren antolamendua L'Être et le Néant obra filosofikoaren "Begirada" kapituluan
No full text344 p.Ikerketa honek J.-P. Sartreren L'Être et le Néant tratatu filosofikoaren idaztankeran jartzen du arreta, eta obra horren irakurketa berri bat eskaintzen du, hain zuzen ere, diskurtso teorikoak baliatzen duen fikzioaren ikuspegitik. "Begirada" kapitulu luze eta funtsezkoa ikerketa-corpustzat hartuta, eta berau euskaratuta, ikerketa honen helburua da baliabide horren eginkizun nagusia ulertzea. Xede horrek eskatzen du ikerketa honi diskurtsoaren analisiaren esparrutik heltzea, fikzioa irizpide enuntziatiboen argitan zedarritzeko eta diskurtso-antolamenduaren baitan ulertzeko. Halatan, ikerketa honek erakusten du, alde batetik, testuko fikzioa diskurtso teoriko nagusiarekiko etendura gisa enuntziatzen dela, teoria beste erregistro batean adierazteko; beste alde batetik, fikzioak adarkadura bat osatzen duela diskurtsoan, horrek parte zuzena duela diskurtsoaren antolamendu teorikoan eta, halaber, testuaren jomuga teorikoa bermatzen duela
Compilation of Published Estimates of Annual Geocenter Motions Using Space Geodesy
No full textThe definition of the term "geocenter motion" depends on the adopted origin of the reference frame. Common reference frames used in Space Geodesy include: the center of mass of the whole Earth (CM), the center of mass of the Solid Earth without mass load (CE), and the center of figure of the outer surface of the Solid Earth (CF). There are two established definitions of the term geocenter: one, the vector offset of CF relative to CM and, two, the reverse, the vector offset of CM relative to CF. Obviously, their amplitude is the same and their phase differs by 180 deg. Following Dong et al. [2003], we label the first X(sub CF, sup CM) and the second X(sup CF, sup CM) (i.e., the superscript represents the frame, the subscript represents any point in the frame)
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