32,474 research outputs found
Impact of PCV10 on nasopharyngeal carriage in children in Pakistan
This data set is from the study "Direct and indirect effect of 10 valent pneumococcal vaccines on the nasopharyngeal carriage in children under 2 years of age in Matiari, Pakistan" published in the journal Vaccine which can be accessed from Nisar MI, Ahmed S, Jehan F, Shahid S, Shakoor S, Kabir F, Hotwani A, Munir S, Muhammad S, Khalid F, Althouse B, Hu H, Whitney C, Rodgers G, Klugman K, Ali A, Zaidi AKM, Omer SB, Iqbal N. Direct and indirect effect of 10 valent pneumococcal vaccines on the nasopharyngeal carriage in children under 2 years of age in Matiari, Pakistan. Vaccine. 2021 Jan 6:S0264-410X(20)31662-5. DOI: 10.1016/j.vaccine.2020.12.066. Epub ahead of print. PMID: 33422379. Data was collected for a time-series cross-sectional study exploring the impact of 10-valent Pneumococcal Conjugate Vaccine (PCV10) on nasopharyngeal (NP) carriage in children under 2 years of age from a rural population in Sindh, Pakistan. The study was carried out in two union councils of Matiari - Khyber and Shah Alam Shah Jee Wasi (Latitude 25.680298 / Longitude 68.502711). Data was collected on socio-demographics, clinical characteristics, and vaccination status using an android phone-based application. NP samples were collected using standard World Health Organisation (WHO) techniques, culture and serotyping were done using sequential Multiplex PCR described by the Centre for Disease Control, USA. We looked at the carriage rate of vaccine-type (VT) and non-vaccine type (NVT) serotypes over time in vaccinated and unvaccinated children. We additionally looked at the predictors for pneumococcal carriage. The study showed a high overall pneumococcal carriage in a large sample of 3140 children enrolled from a rural setting in Pakistan over a period of four years. Vaccine type carriage decreased both in the vaccinated and unvaccinated population indicating herd immunity
Subjectivity in Incentive Pay
I investigate the determinants and effects of subjectivity in incentive pay. New forms of incentive pay are increasingly being introduced by company management – for example, bonuses are now linked to wider business goals, such as quality and customer service, company reputation and employee hiring and retention policies, replacing the traditional focus on output or profit measures. A new conceptual work on subjectivity is used to evaluate these incentive pay practices. The analysis shows that a variety of contextual factors influence the organizations to make greater use of subjectivity in incentive pay. I also discuss the performance effects of subjectivity
The shannon capacity on C(n,k)
This thesis focuses on a problem formulated by Claude Shannon named the Shannon capacity. This problem is about information rate per time unit over a noisy channel. The noisy channel is here represented by a graph. We specifically focus on a class of circulant graphs that are denoted by C(n,k) with vertex set z/nz, where all vertices are connected with the k-1 vertices before and after it. We will discuss upper bounds that were found for the Shannon capacity and how C(n,k) behaves with these upper bounds. After that we will focus on multiple ways to calculate lower bounds for the Shannon capacity of . For these three search methods will be used. These are exhaustive searching for optimal values, optimal ways to make packagings and solutions created by using a special form. As last the answers will be discussed by combining the upper and lower bounds for C(n,k). From this conclusions are drawn after which some possibilities will be given for further research. Applied Mathematic
Measurement of the ratio of branching fractions B(B0→K∗0γ )/B(B0s→φγ ) and the directCP asymmetry inB 0→K∗0γ
The ratio of branching fractions of the radiative B decays B0→K⁎0γ and B0s→ϕγ has been measured using an integrated luminosity of 1.0 fb−1 of pp collision data collected by the LHCb experiment at a centre-of-mass energy of s√=7TeV. The value obtained is
B(B0→K⁎0γ)B(B0s→ϕγ)=1.23±0.06(stat.)±0.04(syst.)±0.10(fs/fd),
where the first uncertainty is statistical, the second is the experimental systematic uncertainty and the third is associated with the ratio of fragmentation fractions fs/fd. Using the world average value for B(B0→K⁎0γ), the branching fraction B(B0s→ϕγ) is measured to be (3.5±0.4)×10−5.
The direct CP asymmetry in B0→K⁎0γ decays has also been measured with the same data and found to be
ACP(B0→K⁎0γ)=(0.8±1.7(stat.)±0.9(syst.))%.
Both measurements are the most precise to date and are in agreement with the previous experimental results and theoretical expectations
The Diophantine equation revisited
Let k,l >= 2 be fixed integers, and C be an effectively computable constant depending only on k and l. In this paper, we prove that all solutions of the equation (x + 1)(k) + (x + 2)(k) + ... + (lx)(k) = y(n) in integers x, y,n with x, y >= 1, n >= 2, k not equal 3 and l 1 (mod 2) satisfy max{x, y, n} < C. The case when is even has already been completed by the second author (see [24])
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
K-theory for group C*-algebras
These notes are based on a lecture course given by the first author in the Sedano Winter School on K-theory held in Sedano, Spain, on January 22-27th of 2007. They aim at introducing K-theory of C*-algebras, equivariant K-homology and KK-theory in the context of the Baum-Connes conjectur
Poetic Formula “I see” in K. N. Batyushkov’s Work: Creative Assimila-tion of the Derzhavin Tradition
The author analyses the visual metaphors of K. N. Batyushkov’s poetry, in which he acts as the creative heir to the artistic style of G. R. Derzhavin. The urgency of the problem is connected with the need to clarify the features of the creative method of K. N. Batyushkov in the aspect of his assimilation of the Derzhavin tradition. The novelty of the research is connected with the expansion of ideas about the poetics of the visual in Russian poetry of the early 19th century, in particular, in the work of K. N. Batyushkov. It is proved that K. N. Batyushkov represents vision as a process of cognition of the world. The mechanisms of K. N. Batyushkov’s transformation of visually perceived world in an artistic image are considered, the artistic thinking of the poet is reconstructed. It is revealed that the model of creating a visual verbal image in K. N. Batyushkov’s work is based on the poetic formula “I see.” It is shown that K. N. Batyushkov emphasizes the position of the observer, reflecting at the same time on the diversity and greatness of God’s world, on the cause-and-effect relationship of reality phenomena. It is established that a special place is given to the representation of historical events in the work of the poet: through the poetic formula “I see” K. N. Batyushkov places himself inside the picture, which corresponds to the emerging aesthetics of romanticism with its cult of personal perception of reality
Permutations fixing a k-set
Let i(n,k) be the proportion of permutations π∈Sn having an invariant set of size k. In this note, we adapt arguments of the second author to prove that i(n,k)≍k−δ(1+logk)−3/2 uniformly for 1≤k≤n/2, where δ=1−1+loglog2log2. As an application, we show that the proportion of π∈Sn contained in a transitive subgroup not containing An is at least n−δ+o(1) if n is even
Efficacy and safety of selegiline across different psychiatric disorders: A systematic review and meta-analysis of oral and transdermal formulations
Selegiline is an irreversible, selective type-B monoamine oxidase inhibitor (MAOI) approved for Parkison's disease—oral and major depressive disorder—transdermal formulation) resulting in non-selective MAOI activity at oral doses≥20 mg/day. The present systematic review and meta-analysis appraises the evidence of different formulations/dosages of selegiline across different psychiatric conditions. We inquired PubMed/MEDLINE/Cochrane-Central/WHO-ICTRP/Clarivate-WebOfScience and the Chinese-Electronic-Journal Database from inception to 10/26/2022 for selegiline trials involving psychiatric patients. Random-effects meta-analyses assessed heterogeneity, publication/risk biases, and confidence in the evidence, followed by sensitivity, subgroup, and meta-regression analyses. Co-primary outcomes were: changes in symptom score (standardized mean difference=SMD) and author-defined response (risk ratios=RRs). RRs of adverse events and all-cause discontinuation were secondary and acceptability outcomes, respectively. Systematic-review included 42 studies; meta-analysis, 23. Selegiline outperformed placebo in depressive symptom reduction (SMD=-0.96, 95%C.I.=-1.78, -0.14, k = 10, n = 1,308), depression (RR=1.61, 95%C.I.=1.20, 2.15, k = 9, n = 1,238) and atypical-depression response (RR=2.23, 95%C.I.=1.35, 3.68, k = 3, n = 136). Selegiline failed to outperform the placebo in negative (k = 4) or positive symptoms of schizophrenia (k = 4), attention-deficit-hyperactivity disorder (ADHD) symptoms reduction (k = 2), and smoking abstinence rate (k = 4). Selegiline did not differ from methylphenidate and ADHD scores (k = 2). No significant difference emerged in acceptability, incident diarrhea, headache, dizziness, and nausea RRs, in contrast to xerostomia (RR=1.58, 95%C.I. =1.03, 2.43, k = 6, n = 1,134), insomnia (RR=1.61, 95%C.I.=1.19, 2.17, k = 10, n = 1,768), and application-site reaction for transdermal formulation (RR=1.81, 95%C.I.=1.40, 2.33, k = 6, n = 1,662). Confidence in findings was low/very-low for most outcomes; moderate for depressive symptoms reduction (transdermal). Selegiline proved effective, safe, and well-tolerated for depressive disorders, yet further evidence is warranted about specific psychiatric disorders
- …
