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Book Review: New Views of the Moon, B. L. Jolliff, M. A. Wieczorek, C. K. Shearer, C. R. Neal (Eds.)
No full textBook Review: New Views of the Moon, B. L. Jollif, M. A. Wieczorek, C. K. Shearer, C. R. Neal (Eds.). Mineralogical Society of America (2006).The Meteoritics & Planetary Science archives are made available by the Meteoritical Society and the University of Arizona Libraries. Contact [email protected] for further information.Migrated from OJS platform February 202
Nelson & Neal Piano Duo at Winston-Salem State College
No full textAllison Nelson & Harry Neal were an Australian-American couple and pianists who performed together throughout the United States during the 50s and 60s. When they appeared at Winston-Salem State College in 1967, they posed for photos with school president K. R. Williams (left), unidentified woman, Nelson and Neal
Legal Commentary - R v. Human Fertilisation and Embryology Authority, ex parte Blood
No full textDuring the late 1990s and early 2000s, an unprecedented story unfolded in the UK media involving a young widow, Diane Blood, and her legal battle to bear the children of her late husband, Stephen, following his tragic death from meningitis at the age of only thirty. As the story unfolded in the media, the ethical and legal issues were explored in the courts and in academic commentaries.1 For all the controversy the case generated, the applicable law was clear and straightforward: the governing statute at the time of the case, the Human Fertilisation and Embryology Act 1990 (hereafter ‘the Act’), prohibited the storage or use of gametes without the clear written consent of the gamete provider.2 Since the Act was unambiguous, and since Stephen Blood had never given his written consent to the storage or use of his sperm, there was no possibility of the HFEA permitting treatment within the UK. The question, therefore, was whether the HFEA would authorise the removal of the sperm abroad for treatment in another EU country. Initially, they refused, so the issue became a procedural one: had the HFEA reached their decision after appropriate consideration of the various factors which they were obliged to take into account? My concern here is not to examine the points of law which were directly at stake in the case, but to identify some wider themes which have relevance beyond the case itself and examine them from a predominantly (though not exclusively) legal perspective
Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution
No full textNon-steroidal anti-inflammatory drugs (NSAIDs) contribute to gastrointestinal ulcer formation by inhibiting epithelial cell migration and mucosal restitution; however, the drug-affected signaling pathways are poorly defined. We investigated whether NSAID inhibition of intestinal epithelial migration is associated with depletion of intracellular polyamines, depolarization of membrane potential (Em) and altered surface expression of K+ channels. Epithelial cell migration in response to the wounding of confluent IEC-6 and IEC-Cdx2 monolayers was reduced by indomethacin (100μM), phenylbutazone (100μM) and NS-398 (100μM) but not by SC-560 (1μM). NSAID-inhibition of intestinal cell migration was not associated with depletion of intracellular polyamines. Treatment of IEC-6 and IEC-Cdx2 cells with indomethacin, phenylbutazone and NS-398 induced significant depolarization of Em, whereas treatment with SC-560 had no effect on Em. The Em of IEC-Cdx2 cells was: −38.5±1.8mV under control conditions; −35.9±1.6mV after treatment with SC-560; −18.8±1.2mV after treatment with indomethacin; and −23.7±1.4mV after treatment with NS-398. Whereas SC-560 had no significant effects on the total cellular expression of Kv1.4 channel protein, indomethacin and NS-398 decreased not only the total cellular expression of Kv1.4, but also the cell surface expression of both Kv1.4 and Kv1.6 channel subunits in IEC-Cdx2. Both Kv1.4 and Kv1.6 channel proteins were immunoprecipitated by Kv1.4 antibody from IEC-Cdx2 lysates, indicating that these subunits co-assemble to form heteromeric Kv channels. These results suggest that NSAID inhibition of epithelial cell migration is independent of polyamine-depletion, and is associated with depolarization of Em and decreased surface expression of heteromeric Kv1 channels.ID: S0006295207001931; M3: Article; Accession Number: S0006295207001931; Author: L.C. Freeman (b); Author: D.F. Narvaez (a); Author: A. McCoy (a); Author: F.B. von Stein (c); Author: S. Young (b); Author: K. Silver (a); Author: S. Ganta (b); Author: D. Koch (b); Author: R. Hunter (b); Author: R.F. Gilmour (c); Author: J.D. Lillich (a, ⁎); Affiliation: Department of Clinical Sciences, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, United States; Keyword: Non-steroidal anti-inflammatory drugs; Keyword: Intestinal epithelial cells; Keyword: Membrane potential; Keyword: Potassium channels; Number of Pages: 12; Language: English;Source type: Electronic(1)http://search.ebscohost.com/login.aspx?direct=true&db=edselp&AN=S0006295207001931&site=eds-live&scope=sit
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Measurement of the ratio of branching fractions B(B0→K∗0γ )/B(B0s→φγ ) and the directCP asymmetry inB 0→K∗0γ
No full textThe ratio of branching fractions of the radiative B decays B0→K⁎0γ and B0s→ϕγ has been measured using an integrated luminosity of 1.0 fb−1 of pp collision data collected by the LHCb experiment at a centre-of-mass energy of s√=7TeV. The value obtained is
B(B0→K⁎0γ)B(B0s→ϕγ)=1.23±0.06(stat.)±0.04(syst.)±0.10(fs/fd),
where the first uncertainty is statistical, the second is the experimental systematic uncertainty and the third is associated with the ratio of fragmentation fractions fs/fd. Using the world average value for B(B0→K⁎0γ), the branching fraction B(B0s→ϕγ) is measured to be (3.5±0.4)×10−5.
The direct CP asymmetry in B0→K⁎0γ decays has also been measured with the same data and found to be
ACP(B0→K⁎0γ)=(0.8±1.7(stat.)±0.9(syst.))%.
Both measurements are the most precise to date and are in agreement with the previous experimental results and theoretical expectations
The Bolocam Galactic Plane Survey. VII. Characterizing the properties of massive star-forming regions
No full textWe present the results of a Green Bank Telescope survey of NH(3)(1,1), (2,2), (3,3) lines toward 631 Bolocam Galactic Plane Survey (BGPS) sources at a range of Galactic longitudes in the inner Galaxy. We have detected the NH(3)(1,1) line toward 72% of our targets (456), demonstrating that the high column density features identified in the BGPS and other continuum surveys accurately predict the presence of dense gas. We have determined kinematic distances and resolved the distance ambiguity for all BGPS sources detected in NH(3). The BGPS sources trace the locations of the Scutum and Sagittarius spiral arms, with the number of sources peaking between R(Gal) similar to 4 and 5 kpc. We measure the physical properties of each source and find that depending on the distance, BGPS sources are primarily clumps, with some cores and clouds. We have examined the physical properties as a function of Galactocentric distance, and find a mean gas kinetic temperature of 15.6 K, and that the NH(3) column density and abundance decrease by nearly an order of magnitude between R(Gal) similar to 3 and 11 kpc. Comparing sources at similar distances demonstrates that the physical properties are indistinguishable, which suggests a similarity in clump structure across the Galactic disk. We have also compared the BGPS sources to criteria for efficient star formation presented independently by Heiderman et al. and Lada et al., and for massive star formation presented by Kauffmann et al. Forty-eight percent of our sample should be forming stars (including massive stars) with high efficiency, and 87% contain subregions that should be efficiently forming stars. Indeed, we find that 67% of the sample exhibit signs of star formation activity based on an association with a mid-infrared source.National Science Foundation AST-0708403, AST-0607793, AST-1003134, AST-0808119, AST-9800334, AST-0098562, AST-0100793National Radio Astronomy Observatory (NRAO) GSSP09-0004Natural Sciences and Engineering Research Council CanadaScience and Technology Facilities Council of the UKCanadian Space AgencyCSIRO OCEAstronom
Superoxide dismutase 2 knockdown leads to defects in locomotor activity, sensitivity to paraquat, and increased cuticle pigmentation in Tribolium castaneum
No full textCitation: Tabunoki, H., Gorman, M. J., Dittmer, N. T., & Kanost, M. R. (2016). Superoxide dismutase 2 knockdown leads to defects in locomotor activity, sensitivity to paraquat, and increased cuticle pigmentation in Tribolium castaneum. Scientific Reports, 6, 8. doi:10.1038/srep29583Insects can rapidly adapt to environmental changes through physiological responses. The red flour beetle Tribolium castaneum is widely used as a model insect species. However, the stress-response system of this species remains unclear. Superoxide dismutase 2 (SOD2) is a crucial antioxidative enzyme that is found in mitochondria. T. castaneum SOD2 (TcSOD2) is composed of 215 amino acids, and has an iron/manganese superoxide dismutase domain. qRT-PCR experiments revealed that TcSOD2 was present through all developmental stages. To evaluate TcSOD2 function in T. castaneum, we performed RNAi and also assessed the phenotype and antioxidative tolerance of the knockdown of TcSOD2 by exposing larvae to paraquat. The administration of paraquat resulted in significantly higher 24-h mortality in TcSOD2 knockdown larval groups than in the control groups. The TcSOD2 knockdown adults moved significantly more slowly, had lower ATP content, and exhibited a different body color from the control groups. We found that TcSOD2 dsRNA treatment in larvae resulted in increased expression of tyrosinase and laccase2 mRNA after 10 days. This is the first report showing that TcSOD2 has an antioxidative function and demonstrates that T. castaneum may use an alternative antioxidative system when the SOD2-based system fails
Correction to: Bican, R., Christensen, C., Fallieras, K., Sagester, G., O’Rourke, S., Byars, M., & Tanner, K. (2021). Rapid Implementation of Telerehabilitation for Pediatric Patients During COVID-19
No full textCorrection to: Bican, R., Christensen, C., Fallieras, K., Sagester, G., O’Rourke, S., Byars, M., & Tanner, K. (2021). Rapid Implementation of Telerehabilitation for Pediatric Patients During COVID-19. International Journal of Telerehabilitation, 13(1). https://doi.org/10.5195/ijt.2021.6371
The affiliation for each author was incorrectly stated as: Physical Medicine & Rehabilitation, Children’s Minnesota, Minneapolis, Minnesota, USA
The correct affiliation for each author is: Clinical Therapies, Nationwide Children’s Hospital, Columbus, Ohio, USA
The metadata for the original article has been corrected
Annual meeting of the Lunar Exploration Analysis Group : October 22–24, 2012, Greenbelt, Maryland
No full textThe focus of this meeting will be a discussion of the ongoing contributions of the Apollo program to solar system exploration and options and opportunities for the next decade of lunar science and exploration. This meeting will include presentations and discussions on science objectives, robotic and human exploration strategies and technologies, critical required technology development commercial opportunities, education and outreach, and the Moon as a necessary stepping stone to the rest of the solar system.Sponsor: National Aeronautics and Space AdministrationConveners: Charles Shearer, University of New Mexico, Jeffrey Plescia, The John Hopkins Applied Physics Laboratory, Clive Neal, University of Notre Dame, Stephen Mackwell, Lunar and Planetary Institute.PARTIAL CONTENTS: Volatile Extraction and In Situ Resource Utilization for the Moon Applied to Near Earth Objects / E. H. Cardiff--A Revisit to Apollo Magnetic Field Records for Sounding of the Lunar Interior / P. J. Chi--LunarCube: Payload Development for Enhanced Yet Low Cost Lunar Exploration / P. E. Clark, R. MacDowall, R. Cox, A. Vasant, S. Schaire, and B. Malphrus--Frontier: Towards Onboard Intelligence for More Capable Next Generation Space Assets / P. E. Clark, M. L. Rilee, and S. A. Curtis--Near Real-Time Prospecting for Lunar Volatiles: Demonstrating RESOLVE Science in the Field / A. Colaprete, R. Elphic, J. Heldmann, K. Ennico, G. Mattes, and J. Sanders--Gateways to the Solar System: Innovative Advanced Magnet Lab Mass Driver Launch Platforms at L1 and L--R. Cox, P. Clark, A. Vasant, and R. Meinke--Modal Evaluation of Fluid Volume in Spacecraft Propellant Tanks / K. M. Crosby, R. Werlink, S. Mathe, and K. Lubick--Ground Data Systems for Real Time Lunar Science / M. C. Deans, T. Smith, D. S. Lees, E. B. Scharff, T. E. Cohen, and D. S. S. Lim
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