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    MAGNETIC NEEDLE FOR INJECTION AND CONTROLLED RELEASE OF ACTIVE INGREDIENTS FROM MAGNETIC NANOPARTICLES Fe3O4Fe_{3}O_{4}

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    Već duži niz godina se magnetske nanočestice Fe3O4Fe_{3}O_{4} u medicini koriste kao nanonosači za dostavu aktivnih tvari (lijekova). Ovakav način dostave donosi nove mogućnosti za liječenje te dostavu lijekova do teže dostupnih mjesta u ljudskom organizmu. Porozna struktura nanočestica daje mogućnost adsorpcije velike količine kemijski aktivnih tvari (lijekova) na nanočestice. Zbog nanometarskih dimenzija čestica i superparamagnetskih svojstava, moguće ih je vrlo lako manipulirati vanjskim magnetskim poljima. Učinkovito otpuštanje kemijski aktivnih tvari s površine nanočestica moguće je uz asistenciju permanentnog i izmjeničnog magnetskog polja. U završnom dijelu rada je predstavljen prototip magnetske injekcije za prikupljanje nanočestica u organizmu nakon otpuštanja lijeka, kako bi se izbjegle neželjene posljedice koje nastaju prilikom dugotrajnog ostanka nanočestica u organizmu.For many years magnetic nanoparticles Fe3O4Fe_{3}O_{4} are used in medicine as nanocarriers for the delivery of active substances (drugs). This method potentially gives a new method of treatment for less accessible parts of the human body. The porous structure of nanoparticles gives a potentially large area for adsorption of large quantity chemically active substances. Regarding the very small dimensions of particles, they have a high magnetization, and they are relatively easy to manipulate with external magnetic fields. The release of active substances from the surface of nanoparticles occurs due to a combination of the external AC and DC magnetic fields. At the final part of the thesis is presented the prototype of the magnetic needle, which is designed to pick up nanoparticles left in the human body after the treatment, to prevent unwanted longterm side effects

    Superparamagnetic nanoparticles, magnetic properties and application

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    Kroz ovaj završni rad predstavljene su superparamagnetske nanočestice, njihovo ponašanje te primjene u medicini i tehnologiji. Objašnjena su najbitnija magnetska ponašanja i fenomeni, poput Neelova vremena relaksacije, temperature blokiranja, ZFC i FC krivulja te krivulja magnetske histereze. Također su navedene i objašnjene različite vrste magnetizma u materijalima. U završnom dijelu prikazane su najznačajnije primjene superparamagnetskih nanočestica u poljima IT industrije, medicine i tehnologije.Through this thesis superparamagnetic nanoparticles have been presented. The most important magnetic properties and phenomena of magnetic nanoparticles are explained, such as Neel's relaxation time, blocking temperature, ZFC and FC curves, hysteresis curves. In the first part of thesis, magnetic behavior are generally explained with classification of all types of magnetism in the materials. Further, the focus of this research is on magnetic properties and applications of nano-sized object (nanoparticles). Finally, in the last part of the work are presented applications of magnetic nano-materials in different parts of technology and medicine

    NAPOLEONOVA EKSPEDICIJA U EGIPAT

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    Napoleonova ekspedicija u Egipat započela je 1798.g. i trajala je do 1801.godine. Razlozi ekspedicije su višestruki, od novih prekomorskih posjeda do slabljenja britanske moći i utjecaja, osim toga Napoleon je imao i privatne razloge. Francuski direktorij je za ekspediciju osigurao preko 30 tisuća ljudi te veliku flotu za transport. Putem do Egipta osvojena je i Malta, čija je strateška vrijednost ogromna. Pri dolasku u Egipat prvo je zauzeta Aleksandrija, zatim se preko teškog marša kroz pustinju došlo do Kaira. Prije zauzimanja Kaira došlo je do glasovite Bitke kod piramida u kojoj je Napoleon porazio dva glavna mamleučka bega; Ibrahim bega i Murat bega. Nakon te bitke Francuzi ulaze u Kairo. Slijedećih nekoliko mjeseci je potrošeno na niz manjih okršaja u kojima je uništen mamleučki otpor, zatim su Francuzi pokušali pacificirati lokalno stanovništvo, što im nije pošlo za rukom te je kulminiralo pobunom u Kairu. U međuvremenu je britanska flota uništila francusku, što je ostavilo vojsku zarobljenom u Egiptu. Suočen s teškom situacijom i s opasnošću od invazije Osmanske vojske, Napoleon se odlučuje na invaziju Sirije. Kampanja u Siriji je trajala nekoliko mjeseci i kulminirala je opsadom Akre koju Napoleon nije mogao zauzeti, uslijedilo je teško povlačenje natrag u Egipat. Nakon povratka Napoleon je porazio još jednu osmansku vojsku kod Aboukira, ali situacija u Egiptu je bila sve lošija i Napoleon je čuvši za vijesti iz Europe, odlučio napustiti zemlju i vratiti se u Francusku. Nakon odlaska vrhovnog zapovjednika, vojska je izgubila moral te se nakon iskrcavanja britanske vojske morala predati. Uz vojni i politički aspekt, ekspedicija je imala i znanstvenu stranu, 150 različitih znanstvenika i učenjaka je pratilo ekspediciju i u Egiptu došlo do raznih otkrića, od kojih he daleko najpoznatiji i najbitniji kamen iz Rossete, koji je omogućio dešifriranje hijeroglifa. Ekspedicija je trajala 3 godine i završila je neuspjehom, međutim ostavila je neizbrisiv trag na svjetsku povijest i jako je utjecala na Napoleona kojeg je Egipat promijenio te je zasigurno imala ulogu u njegovom daljnjem napretku što ga je dovelo do carskog prijestolja.Napoleon's expedition to Egypt began in 1798 and lasted until 1801. The reasons for the expedition were multiple, ranging from acquiring new overseas territories to weakening British power and influence. Additionally, Napoleon had personal motives. The French Directory provided more than 30,000 men and a large fleet for transport. On the way to Egypt, Malta was conquered, whose strategic value was immense. Upon arriving in Egypt, Alexandria was first captured, followed by a difficult march through the desert to Cairo. Before capturing Cairo, there was the famous Battle of the Pyramids in which Napoleon defeated two main Mamluk beys: Ibrahim Bey and Murad Bey. After this battle, the French entered Cairo. The next few months were spent on a series of smaller skirmishes that crushed the Mamluk resistance. Then the French tried to pacify the local population, but they were unsuccessful, which culminated in a revolt in Cairo. Meanwhile, the British fleet destroyed the French one, leaving the army stranded in Egypt. Faced with a difficult situation and the threat of an Ottoman invasion, Napoleon decided to invade Syria. The Syrian campaign lasted several months and culminated in the siege of Acre, which Napoleon could not capture. This was followed by a difficult retreat back to Egypt. After returning, Napoleon defeated another Ottoman army at Aboukir, but the situation in Egypt continued to worsen. Hearing news from Europe, Napoleon decided to leave the country and return to France. After the departure of the supreme commander, the army lost morale and, after the British forces landed, was forced to surrender. In addition to the military and political aspects, the expedition also had a scientific side. 150 different scientists and scholars accompanied the expedition and made various discoveries in Egypt, the most famous and important of which was the Rosetta Stone, which enabled the deciphering of hieroglyphs. The expedition lasted for 3 years and ended in failure. However, it left an indelible mark on world history and had a significant impact on Napoleon, as Egypt changed him and certainly played a role in his future rise to the imperial throne

    Economic aspects of the catering business

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    Potrebe, kao i očekivanja turista, zahvaljujući globalizaciji kao i razvoju tehnologije neprestano rastu i mijenjaju se. S obzirom na zahtijevnost potražnje potrošača, ugostiteljska ponuda mora se prilagoditi aktualnom turističkom kretanju u svijetu na način da neprestano poboljšava svoje mogućnosti u turističkim jednicima diljem svijeta. Ugostiteljstvo je djelatnost kojoj se pridaje posebna pažnja s obzirom da usluge te djelatnosti značajno utječu na zadovoljstvo turista, odnosno gostiju. U gospodarstvu Republike Hrvatske ugostiteljstvo predstavlja vrlo važnu gospodarsku djelatnost. Ono što ugostiteljstvo čini najperspektivnijom granom gospodarstva jest spektakularan razvoj turizma. Svako hotelsko poduzeće ima svojih pozitivnih i negativnih efekata, no potrebno je provoditi stalna istraživanja i statističke analize kako bi se pozitivne strane mogle i dalje razvijati, a negativne pretvoriti u prednosti. U ovom se radu analiziraju ekonomski aspekti poslovanja ugostiteljskog objekta. Praktični dio rada odnosi se na analizu poduzeća Liburnia Riviera Hoteli d.d. (LRH) koja će detaljnije objasniti ekonomske aspekte poslovanja odabranog ugostiteljskog objekta

    NAPOLEONOVA EKSPEDICIJA U EGIPAT

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    Napoleonova ekspedicija u Egipat započela je 1798.g. i trajala je do 1801.godine. Razlozi ekspedicije su višestruki, od novih prekomorskih posjeda do slabljenja britanske moći i utjecaja, osim toga Napoleon je imao i privatne razloge. Francuski direktorij je za ekspediciju osigurao preko 30 tisuća ljudi te veliku flotu za transport. Putem do Egipta osvojena je i Malta, čija je strateška vrijednost ogromna. Pri dolasku u Egipat prvo je zauzeta Aleksandrija, zatim se preko teškog marša kroz pustinju došlo do Kaira. Prije zauzimanja Kaira došlo je do glasovite Bitke kod piramida u kojoj je Napoleon porazio dva glavna mamleučka bega; Ibrahim bega i Murat bega. Nakon te bitke Francuzi ulaze u Kairo. Slijedećih nekoliko mjeseci je potrošeno na niz manjih okršaja u kojima je uništen mamleučki otpor, zatim su Francuzi pokušali pacificirati lokalno stanovništvo, što im nije pošlo za rukom te je kulminiralo pobunom u Kairu. U međuvremenu je britanska flota uništila francusku, što je ostavilo vojsku zarobljenom u Egiptu. Suočen s teškom situacijom i s opasnošću od invazije Osmanske vojske, Napoleon se odlučuje na invaziju Sirije. Kampanja u Siriji je trajala nekoliko mjeseci i kulminirala je opsadom Akre koju Napoleon nije mogao zauzeti, uslijedilo je teško povlačenje natrag u Egipat. Nakon povratka Napoleon je porazio još jednu osmansku vojsku kod Aboukira, ali situacija u Egiptu je bila sve lošija i Napoleon je čuvši za vijesti iz Europe, odlučio napustiti zemlju i vratiti se u Francusku. Nakon odlaska vrhovnog zapovjednika, vojska je izgubila moral te se nakon iskrcavanja britanske vojske morala predati. Uz vojni i politički aspekt, ekspedicija je imala i znanstvenu stranu, 150 različitih znanstvenika i učenjaka je pratilo ekspediciju i u Egiptu došlo do raznih otkrića, od kojih he daleko najpoznatiji i najbitniji kamen iz Rossete, koji je omogućio dešifriranje hijeroglifa. Ekspedicija je trajala 3 godine i završila je neuspjehom, međutim ostavila je neizbrisiv trag na svjetsku povijest i jako je utjecala na Napoleona kojeg je Egipat promijenio te je zasigurno imala ulogu u njegovom daljnjem napretku što ga je dovelo do carskog prijestolja.Napoleon's expedition to Egypt began in 1798 and lasted until 1801. The reasons for the expedition were multiple, ranging from acquiring new overseas territories to weakening British power and influence. Additionally, Napoleon had personal motives. The French Directory provided more than 30,000 men and a large fleet for transport. On the way to Egypt, Malta was conquered, whose strategic value was immense. Upon arriving in Egypt, Alexandria was first captured, followed by a difficult march through the desert to Cairo. Before capturing Cairo, there was the famous Battle of the Pyramids in which Napoleon defeated two main Mamluk beys: Ibrahim Bey and Murad Bey. After this battle, the French entered Cairo. The next few months were spent on a series of smaller skirmishes that crushed the Mamluk resistance. Then the French tried to pacify the local population, but they were unsuccessful, which culminated in a revolt in Cairo. Meanwhile, the British fleet destroyed the French one, leaving the army stranded in Egypt. Faced with a difficult situation and the threat of an Ottoman invasion, Napoleon decided to invade Syria. The Syrian campaign lasted several months and culminated in the siege of Acre, which Napoleon could not capture. This was followed by a difficult retreat back to Egypt. After returning, Napoleon defeated another Ottoman army at Aboukir, but the situation in Egypt continued to worsen. Hearing news from Europe, Napoleon decided to leave the country and return to France. After the departure of the supreme commander, the army lost morale and, after the British forces landed, was forced to surrender. In addition to the military and political aspects, the expedition also had a scientific side. 150 different scientists and scholars accompanied the expedition and made various discoveries in Egypt, the most famous and important of which was the Rosetta Stone, which enabled the deciphering of hieroglyphs. The expedition lasted for 3 years and ended in failure. However, it left an indelible mark on world history and had a significant impact on Napoleon, as Egypt changed him and certainly played a role in his future rise to the imperial throne

    NAPOLEONOVA EKSPEDICIJA U EGIPAT

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    Napoleonova ekspedicija u Egipat započela je 1798.g. i trajala je do 1801.godine. Razlozi ekspedicije su višestruki, od novih prekomorskih posjeda do slabljenja britanske moći i utjecaja, osim toga Napoleon je imao i privatne razloge. Francuski direktorij je za ekspediciju osigurao preko 30 tisuća ljudi te veliku flotu za transport. Putem do Egipta osvojena je i Malta, čija je strateška vrijednost ogromna. Pri dolasku u Egipat prvo je zauzeta Aleksandrija, zatim se preko teškog marša kroz pustinju došlo do Kaira. Prije zauzimanja Kaira došlo je do glasovite Bitke kod piramida u kojoj je Napoleon porazio dva glavna mamleučka bega; Ibrahim bega i Murat bega. Nakon te bitke Francuzi ulaze u Kairo. Slijedećih nekoliko mjeseci je potrošeno na niz manjih okršaja u kojima je uništen mamleučki otpor, zatim su Francuzi pokušali pacificirati lokalno stanovništvo, što im nije pošlo za rukom te je kulminiralo pobunom u Kairu. U međuvremenu je britanska flota uništila francusku, što je ostavilo vojsku zarobljenom u Egiptu. Suočen s teškom situacijom i s opasnošću od invazije Osmanske vojske, Napoleon se odlučuje na invaziju Sirije. Kampanja u Siriji je trajala nekoliko mjeseci i kulminirala je opsadom Akre koju Napoleon nije mogao zauzeti, uslijedilo je teško povlačenje natrag u Egipat. Nakon povratka Napoleon je porazio još jednu osmansku vojsku kod Aboukira, ali situacija u Egiptu je bila sve lošija i Napoleon je čuvši za vijesti iz Europe, odlučio napustiti zemlju i vratiti se u Francusku. Nakon odlaska vrhovnog zapovjednika, vojska je izgubila moral te se nakon iskrcavanja britanske vojske morala predati. Uz vojni i politički aspekt, ekspedicija je imala i znanstvenu stranu, 150 različitih znanstvenika i učenjaka je pratilo ekspediciju i u Egiptu došlo do raznih otkrića, od kojih he daleko najpoznatiji i najbitniji kamen iz Rossete, koji je omogućio dešifriranje hijeroglifa. Ekspedicija je trajala 3 godine i završila je neuspjehom, međutim ostavila je neizbrisiv trag na svjetsku povijest i jako je utjecala na Napoleona kojeg je Egipat promijenio te je zasigurno imala ulogu u njegovom daljnjem napretku što ga je dovelo do carskog prijestolja.Napoleon's expedition to Egypt began in 1798 and lasted until 1801. The reasons for the expedition were multiple, ranging from acquiring new overseas territories to weakening British power and influence. Additionally, Napoleon had personal motives. The French Directory provided more than 30,000 men and a large fleet for transport. On the way to Egypt, Malta was conquered, whose strategic value was immense. Upon arriving in Egypt, Alexandria was first captured, followed by a difficult march through the desert to Cairo. Before capturing Cairo, there was the famous Battle of the Pyramids in which Napoleon defeated two main Mamluk beys: Ibrahim Bey and Murad Bey. After this battle, the French entered Cairo. The next few months were spent on a series of smaller skirmishes that crushed the Mamluk resistance. Then the French tried to pacify the local population, but they were unsuccessful, which culminated in a revolt in Cairo. Meanwhile, the British fleet destroyed the French one, leaving the army stranded in Egypt. Faced with a difficult situation and the threat of an Ottoman invasion, Napoleon decided to invade Syria. The Syrian campaign lasted several months and culminated in the siege of Acre, which Napoleon could not capture. This was followed by a difficult retreat back to Egypt. After returning, Napoleon defeated another Ottoman army at Aboukir, but the situation in Egypt continued to worsen. Hearing news from Europe, Napoleon decided to leave the country and return to France. After the departure of the supreme commander, the army lost morale and, after the British forces landed, was forced to surrender. In addition to the military and political aspects, the expedition also had a scientific side. 150 different scientists and scholars accompanied the expedition and made various discoveries in Egypt, the most famous and important of which was the Rosetta Stone, which enabled the deciphering of hieroglyphs. The expedition lasted for 3 years and ended in failure. However, it left an indelible mark on world history and had a significant impact on Napoleon, as Egypt changed him and certainly played a role in his future rise to the imperial throne

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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