508 research outputs found

    Longitudinal profiling and tracking stability in the Singapore study of macro-angiopathy and microvascular reactivity in type 2 diabetes cohort

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    The Singapore Study of Macro-Angiopathy and microvascular Reactivity in Type 2 Diabetes (SMART2D) is a prospective cohort study which was started in 2011 to investigate the effect of risk factors on vascular function and diabetes-related complications in Asians. We aimed to compare the longitudinal change in risk factors by accounting for batch effect and assess the tracking stability of risk factors over time in patients recruited for SMART2D. In this study, we (1) described batch effect and its extent across a heterogenous range of longitudinal data parameters; (2) mitigated batch effect through statistical approach; and (3) assessed the tracking stability of the risk factors over time.Ministry of Health (MOH)National Medical Research Council (NMRC)Published versionThe SMART2D cohort is supported by the Singapore Ministry of Health’s National Medical Research Council under its CSIRG (MOH-000066). The corresponding author is supported by the Singapore Ministry of Health’s National Medical Research Council under its Clinician Scientist Award (NMRC/CSA-INV/ 0020/2017). The first author is supported by the Singapore Ministry of Health’s National Medical Research Council under its Research Training Fellowship (NMRC/MOH000226)

    Association between lower phase angle and chronic kidney disease progression in type 2 diabetes patients

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    Introduction: Phase angle (PhA), derived from bioelectrical impedance analysis (BIA), is the angle of vector determined by the body’s resistance and reactance. It indicates cellular integrity and hydration status. Though extracellular volume excess was associated with chronic kidney disease (CKD) progression, the association between PhA and CKD progression is unknown. Matrix metalloproteinase-2 (MMP-2) is a member of zinc-dependent endopeptidase family and promotes renal interstitial fibrosis. We investigated association between PhA and CKD progression, and whether the association was through MMP-2 in patients with type 2 diabetes mellitus (T2DM). Method: We conducted a prospective study on 1,078 patients with T2DM (mean age 58.9±9.1 years). PhA was measured using BIA. CKD progression was defined as ≥25% decrease in estimated glomerular filtration rate (eGFR) from baseline with deterioration across eGFR categories. Multiplex immunoassay was used to quantitate MMP-2. We examined association between PhA and CKD progression using Cox proportional hazards model, adjusting for demographics, clinical parameters and medications. Results: Over 8.6 years of follow-up, 43.7% of participants had CKD progression. Compared to tertile 3 PhA (higher level), tertiles 1 and 2 PhA were associated with higher hazards of CKD progression, with corresponding unadjusted hazard ratios (HRs) of 2.27 (95% confidence interval [CI] 1.80–2.87, P<0.001) and 1.57 (95% CI 1.24–2.01, P<0.001). The positive association between tertiles 1 and 2 PhA with CKD progression persisted in the fully adjusted model with corresponding HRs of 1.71 (95% CI 1.30–2.26, P<0.001) and 1.46 (95% CI 1.13–1.88, P=0.004). MMP-2 accounted for 14.7% of association between tertile 1 PhA and CKD progression. Conclusion: Our findings revealed a previously unobserved association between BIA-derived lower PhA and CKD progression through MMP-2 in patients with T2DM.Ministry of Health (MOH)National Medical Research Council (NMRC)Published versionThis study was supported by the Singapore Ministry of Health’s (MOH) National Medical Research Council (NMRC) under its Clinician Scientist-Individual Research Grant (MOH-000066). The corresponding author is supported by NMRC under its Clinician Scientist Award (NMRC/CSA-INV/0020/2017). The first author is supported by NMRC under its Research Training Fellowship (NMRC/MOH000226)

    Receiving social support from diverse helpers: associations with quality of life

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    More older adults now live in non-family-based households, even as the provision of support to older adults within the domestic setting becomes more salient. This study examines the determinants of having non-immediate family or non-coresident helpers in older adults' received social support networks, and its associations with quality of life. Data were from a nationally representative study of Singaporeans aged 60 and above (N = 2248) who did not live alone. Findings show that those who received help solely from persons other than their spouse or child report a lower quality of life compared to other kinds of networks. However, those who had more non-coresident helpers than co-resident helpers experienced a higher quality of life compared to those who relied mainly on co-resident helpers. We suggest that policymakers should consider supporting a wider range of informal social support arrangements and providers, as networks of received social support become increasingly diverse.Ministry of Education (MOE)Ministry of Health (MOH)The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Transitions in Health, Employment, Social Engagement and Inter- Generational Transfers in Singapore (THE SIGNS) Study, Wave 1, was supported by Ministry of Health, Singapore (MOH) under the agreement number MOH-NUS RL2015-053. This research is also made possible by the Ministry of Education, Singapore, under its Academic Re-search Fund Tier 1 04MNP002436C430

    Integrasi pendidikan ketrampilan dalam kurikulum madrasah di MAN Kendal

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    Moh. Nailul Author (Nim: 3103088), Mahasiswa Fakultas Tarbiyah IAIN Walisongo Semarang, skripsi Integrasi Pendidikan Ketrampilan Dalam Kurikulum Madrasah di MAN Kendal Penelitian ini bertujuan untuk mengetahui: Bagaimana pelaksanaan integrasi pendidikan ketrampilan dalam kurikulum madrasah di MAN Kendal Penelitian ini adalah jenis penelitian kualitatif lapangan, adapun untuk memperoleh data-data yang dipaparkan dalam penelitian ini, penulis menggunakan metode observasi, wawancara, dan dokumentasi, yang kemudian dianalisis dengan menggunakan metode analisis deskriptif kualitatif. Program pendidikan ketrampilan sebagai pendidikan yang dapat memberikan bekal ketrampilan yang praktis, terpakai, terkait dengan kebutuhan pasar kerja, peluang usaha dan potensi ekonomi atau industri yang ada di masyarakat. Integrasi pendidikan ketrampilan tidak mengubah kurikulum di madrasah (melaksanakan pendidikan agama dan pendidikan umum). Kurikulum ketrampilan ini dapat diartikan sebagai suatu konsep kurikulum yang menekankan pada pengembangan kemampuan/mempunyai ketrampilan dengan standar performansi tertentu, sehingga hasilnya dapat dirasakan siswa berupa ketrampilan yang dimilikinya. Hasil penelitian menunjukkan bahwa pelaksanaan integrasi kurikulum pendidikan ketrampilan (workshop) di Madrasah Aliyah Negeri Kendal telah berjalan dengan baik. Pendidikan ketrampilan dilaksanakan dalam bentuk intrakurikuler (muatan lokal) dan ekstrakulikuler (program khusus/workshop).. Kurikulum (materi) pendidikan ketrampilan mengacu pada berbagai ragam kemampuan, seperti ketrampilan elektronika, tata busana dan otomotif. Pelaksanaan pendidikan ketrampilan ini untuk dapat mengaktualisasikan potensi-potensi bakat dan minat siswa, agar dapat digunakan untuk memecahkan problem yang dihadapi, ketrampilan yang dimiliki sebagai bekal siswa dalam menghadapi dunia kerja jika siswa tidak melanjutkan studi ke jenjang yang lebih tinggi. Berdasarkan hasil penelitian ini di harapkan akan menjadi bahan informasi dan masukan bagi para civitas akademika, para mahasiswa, para pengajar, dan para peneliti dan semua pihak yang membutuhkan di lingkungan Fakultas Tarbiyah IAIN Walisongo Semarang

    Education and Human Resource Development for Improving the Reputation of Higher Education Institutions

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    This study explores the importance of Human Resource (HR) development in contributing to a university's reputation. This research is qualitative in the form of library research. From the study, it was concluded that improving a university's reputation is highly prioritized through the development of human resources carried out informally and formally. Informally, this effort can be done through self-development programs like training. It can be done by increasing education by continuing studies in the doctoral program (S3). Improving and developing academic qualifications is essentially a personal obligation for each lecturer, so each lecturer is highly recommended to develop a self-development curriculum (KPD) mainly related to developing and implementing the Tri Dharma of Higher Education

    Hubungan Islam dan Negara dalam Negara Hukum: Analisis Pemikiran Moh. Mahfud MD

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    The battle between Islam and the state is well-known, as it began during the process of establishing the Indonesian state, resulting in the division of the country into two groups: Islamic nationalists and secular nationalists. Pancasila, according to Mahfud MD, is a collection of factors aimed at resolving divisions. The purpose of this study is to describe how Moh. Mahfud MD views the link between Islam and the state, what his background is, and how the relationship between Islam and the state functions in a state of law. The author compares the viewpoints of many figures on this subject using a qualitative method with a normative approach. According to the study\u27s findings, Moh. Mahfud MD believes that while religion does not rule the state, the state\u27s structure is a creation rather than a product of political science. The reason for Moh. Mahfud MD\u27s ideas is that they bear a resemblance to Nahdatul Ulama, as Mahfud is involved in alumni activities and was formerly a member. Islam and the state in a state of law share a shared goal: both maintain the democratic system in order to protect human rights.Keywords: Islam; State; State of Law; Pancasila AbstrakPerdebatan Islam dan negara sudah tidak asing lagi, mengingat konflik ini dimulai ketika menentukan dasar negara Indonesia yang mengakibatkan perpecahan menjadi dua golongan antara nasionalis Islam dan nasionalis sekuler. Mahfud MD menyatakan bahwa Pancasila merupakan gabungan aspek yang bertujuan untuk mendamaikan perpecahan. Penelitian ini bertujuan untuk menjelaskan bagaimana pandangan Moh. Mahfud MD tentang hubungan Islam dan negara, apa yang melatar belakangi pemikiran Moh. Mahfud MD, serta bagaimana hubungan Islam dan negara dalam negara hukum? Penulis menggunakan metode kualitatif dengan pendekatan normatif untuk membandingkan pendapat para tokoh terkait hal ini. Hasil penelitian menyatakan bahwa Moh. Mahfud MD memandang agama tidak mengatur negara akan tetapi bentuk negara merupakan ciptaan daripada ilmu politik. Hal yang melatar belakangi pemikiran Moh. Mahfud MD yaitu adanya kemiripan dengan Nahdatul Ulama dikarenakan Mahfud aktif dalam kegiatan alumni sekaligus pernah menjadi anggotanya. Adapun hubungan Islam dan negara dalam negara hukum mempunyai persamaan yaitu sama-sama menjunjung tinggi sistem demokrasi guna menjunjung tinggi hak asasi manusia.Kata Kunci: Islam, Negara, Negara Hukum, Pancasila

    Pelatihan Tes Potensi Akademik (TPA) Logika Untuk SBMPTN dan Memasuki Dunia Kerja Bagi Siswa SMK Muhammadiyah 1 Sukoharjo

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    Tes Potensi Akademik (TPA) adalah tes yang bertujuan untuk melihat sejauh mana kemampuan berpikir peserta didik. Tes ini terdiri pemahaman serta penalaran. Aspek yang diukur dalam TPA ada 4 yakni verbal, numerical, logika, dan figural. Tes ini salah satunya digunakan dalam tes Seleksi Bersama Masuk Perguruan Tinggi Negeri (SBMPTN). Oleh karena itu, bagi siswa kelas XII harus mempersiapkan kemampuan TPA. Selain itu, tes diperuntukan sebagai syarat diterimanya bekerja. Salah satu aspek TPA yang seringkali membuat siswa kesulitan adalah aspek logika. Tujuan kegiatan pengabdian ini adalah memberikan pelatihan bagi siswa SMK Muhammadiyah 1 Sukoharjo tentang tips, trik, dan metode untuk mengerjakan soal TPA Logika. Siswa kelas XII SMK yang akan melanjutkan sekolah ke jenjang selanjutnya adalah yang menjadi sasaran pelatihan. &nbsp;Subjek pelatihan ini adalah 15 siswa kelas XII TKJ 1. Metode pelatihan ini dilakukan dengan dua cara yakni pemaparan secara langsung dan post test untuk mengukur sejauh mana siswa memahami dan mengaplikasikan metode pelatihan. Setelah dilakukan pemaparan oleh pembicara 1 dan 2, pembahasan contoh soal dengan menggunakan metode praktis, selanjutnya diakhir pelatihan diadakan post test. Hasil post test didapatkan hasil akhir bahwa 87% siswa dapat menerima dengan baik pelatihan TPA Logika. &nbsp

    PERANCANGAN APLIKASI ELECTRONIC MEDICAL RECORD (EMR) PADA INSTALASI RAWAT INAP BERBASIS WEB

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    Pelayanan medik dewasa ini membutuhkan sistem yang lebih efektif dan efisien, baik dalam penggunaan waktu, tenaga maupun sarana. Dalam pengelolaan rekam medik, kenyataan masih umumnya penggunaan rekam medik manual yang dinilai tak lagi andal menangani data medik melahirkan ide konversi rekam medik manual kertas ke rekam medik elektronik karena efektivitas dan efisiensinya. Penelitian ini bertujuan menciptakan aplikasi rekam medik elektronik yang lebih dikenal sebagai EMR (Electronic Medical Record) dari rekam medik kertas di Instalasi Rawat Inap Rumah Sakit Umum Ananda Salatiga. Rekam medik elektronik dirancang dengan membuat form-form isian catatan-catatan medik dalam proses perawatan pasien selama dirawat. Data-data medik ini kemudian disimpan dalam basis data sistem dan dikelola secara digital. Setiap kali pengisian data medik pada form-form tertentu, sistem akan menghasilkan kode yang membawa informasi khusus. Pada akhirnya, sistem akan menghasilkan deret kode ICD (International Statistical Classification of Diseases and Related Health Problems) dari kode-kode yang dihasilkan pada pengisian form-form catatan medik. Deretan kode-kode ini mampu menggambarkan perkembangan kondisi pasien dan penanganan medik yang diberikan selama perawatan. Data-data medik yang tersimpan dapat ditampilkan kembali dalam bentuk catatan medik digital. Kata kunci: rekam medik, rawat inap, EMR, IC

    ANALISA.PENGENDALIAN.INTERN DALAM PERSEDIAAN OBAT UNTUK PASIEN PENGGUNA BPJS KESEHATAN. DI RSUD Dr. H. MOH. ANWAR KABUPATEN SUMENEP

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    This.study.aims.to.determine.the.system and.procedure of drug supply in Dr. H. Moh. Anwar, Sumenep Regency. The research method.used by the author is qualitative.with the form of research used that is descriptive. The results of the data analysis showed.that the drug supply system in the Pharmacy department at Dr. RSUD H. Moh. Anwar of Sumenep Regency is already good enough in providing medicines. This causes the existing system to be said to be complete with the separation of duties and the arrangement of supplies which are supported by complementary documents. Recording that has been done can be said to be good to divert things that are detrimental to the Hospital. Supplies Medicines in pharmacy have been done with good and correct systems and proceduresKeywords : Control System, inventory Management and Inventory

    Portofolio Kontrak Kerja PT Cakrawala Muda Mandiri

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    Mangsa. Moh. Sabrin, 2023. (CMM Translation). Counsellor: Dr. Muhammad Fadli Ramadan, S.P.D., M.P.D. The COE Internship Programmeme Arabic Translator, counselled by Muhammadiyah Malang University Arabic Education Studies Programmeme, aims to give the students the opportunity to apply the knowledge learned during the course in a more real world of work. This research covers the job offers received by the author. The company sees and evaluates that the performance of the author for the client is excellent, therefore the author gets the opportunity to work as a technician. The two-month internship programme is scheduled for October 2 and December 2, 2023. Working days at the Youth Independent Horizon are from Monday to Friday. The internship model applied at PT Cakrawala Muda Indiri is full-time. In carrying out his duties as an internship student, the CMM party divided it into two sections: administration and technicians, so the writer gained work experience during the internships taking place in the technician section. In this section, the author is tasked with preparing the device for the interpreter. Therefore, the writer really had good work experience
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