162,417 research outputs found
[Report to Chief J. E. Curry, by an unknown author #1]
Report to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
[Report to Chief J. E. Curry, by an unknown author #2]
Report to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney
Dolasetron and shivering. A prospective randomized placebo-controlled pharmaco-economic evaluation
Background and goal: Forced by the current economical situation, German hospitals have to reconsider their clinical productivity. When caregivers introduce new therapeutic concepts medical quality should either be improved without increasing costs or when reducing costs medical quality should be maintained. In the surgical field postoperative shivering reduces both patient comfort and medical quality. We therefore investigated the clinical pathway prevention of shivering with dolasetron in a prospective, randomized, placebo-controlled analysis of cost-effectiveness. Material and methods. After written informed consent we randomized 40 patients scheduled for lumbar disc hernia repair or head and neck surgery into two groups: patients of group D received dolasetron 1 mg/kg body weight during surgery whereas patients of group K received 100 ml saline as placebo. Primary endpoints were the incidence of shivering, the length of stay in the postanesthesia care unit and process-associated costs. Secondary endpoint was the influence on perioperative thermoregulation. Results. We observed postanesthetic shivering in 5 patients belonging to group D in comparison to 15 patients receiving the placebo (p < 0.05). The length of stay in the postanesthesia care unit was shorter in patients allocated to dolasetron (mean +/- SD; group D: 43 +/- 16 min, group K 62 +/- 18 min, p < 0.05). There was a significant saving in process-associated personnel costs (personnel costs in group D EUR 41.26 +/- 14, personnel costs in group K EUR 53.15 +/- 15) but in contrast the process-associated material costs were significantly increased (group D EUR 17.16 +/- 3, group K EUR 0.73 +/- 1, p < 0.05). Conclusions. The optimization of the clinical process and medical quality induced by a prophylaxis against shivering and postoperative nausea and vomiting compensates for the increased use of pharmaceutical resources in our setting
PSYNDEX Tests Review für ESGRAF-R - Evozierte Sprachdiagnose grammatischer Fähigkeiten - Revidierte Fassung
This is a PSYNDEX Tests Review of ESGRAF-R - Evozierte Sprachdiagnose grammatischer Fähigkeiten - Revidierte Fassung. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries. PSYNDEX Tests is offered by the Leibniz Institute for Psychology as open access documentation.Das ist ein PSYNDEX Tests Review zu ESGRAF-R - Evozierte Sprachdiagnose grammatischer Fähigkeiten - Revidierte Fassung. PSYNDEX Tests Reviews beschreiben und bewerten zentrale psychologische und pädagogische Testverfahren, die in den deutschsprachigen Ländern eingesetzt werden, nach einem standardisierten Raster. PSYNDEX Tests wird durch das Leibniz-Institut für Psychologie als Open Access Dokumentation angeboten.Diagnostische Zielsetzung: Die Zielgruppe des ESGRAF-R sind Kinder und Jugendliche im Alter von 4-16 Jahren, welche erkennbare Auffälligkeiten beim Erwerb des grammatischen Systems ihrer Bezugssprache zeigen. Das Ziel besteht darin, diagnostisch eindeutige Informationen zu erhalten und darauf basierend individuelle Therapieziele zu finden und zu planen. Aufbau: ESGRAF-R ist in fünf Module unterteilt, die in 15 Basis- und Erweiterungsmodule untergliedert sind und insgesamt aus 120 bis 140 Items bestehen: (1) Modul Subjekt-Verb-Kontrollregel, (2) Modul Verbendstellungsregel, (3) Modul Kasusregeln, (4) Modul Genussicherheit, (5) Modul Pluralmarkierung. Je nach Leistung des Kindes werden neben den fünf Basismodulen nicht alle Erweiterungsmodule genutzt. Es ist zudem auch möglich, eine spracherwerbsorientierte Ermittlung des nächsten Therapiezieles durchzuführen, welche nicht auf alle Teile des Gesamtprofils zurückgreift. ESGRAF-R kann sowohl zur Einzeltestung als auch in leicht abgewandelter Form zum Klassenscreening eingesetzt werden. Grundlagen und Konstruktion: Es sollte ein Verfahren entwickelt werden, welches die Fähigkeit zum (1) Kodieren, (2) Dekodieren, (3) Rekonstruieren und (4) Reflektieren von Sätzen misst. Hierzu wurde versucht, die Vorzüge von evozierten Sprachproben zu nutzen. Eine Vorform des sprachdiagnostischen Verfahrens ESGRAF wurde 1988 in der Schweiz auf Berndeutsch entwickelt, erprobt und 1996 ins Deutsche übersetzt. Nach Pilotstudien wurde eine überarbeitete ESGRAF-Version von Motsch (2000) vorgestellt. Zum Ausgleich diverser Nachteile des ESGRAF-Verfahrens wurden drei Ergänzungstests in Interventionsstudien erprobt (Motsch, 2006). ESGRAF-R (Motsch, 2009) ist die darauf basierende revidierte, ergänzte und stark überarbeitete Fassung des ESGRAF (1999). Empirische Prüfung und Gütekriterien: Die Objektivität soll durch Lehrvideos, Anweisungen und Beispiele, die Anwender und Auswerter in ihrem Vorgehen instruieren, sicher gestellt werden. Insbesondere zur Messung der Interraterreliabilität wurden jedoch keine Untersuchungen durchgeführt. Reliabilität: Die Reliabilität des Verfahrens wurde nicht empirisch überprüft. Validität: Zwar existiert Augenscheinvalidität, da grammatische Darbietungen evoziert werden und grammatische Störungen diagnostiziert werden sollen, eine explizite Validierung des Verfahrens ESGRAF-R wurde jedoch nicht durchgeführt. Normen: Es existieren Prozentränge für Schulanfänger, welche aus den Daten von n = 106 Schulneulingen gewonnen wurden. Abgesehen von diesen gibt es nur beispielhafte Vorgaben und Orientierungsrichtlinien, jedoch keine Normwerte.publishedVersio
Murder on the mountain: author talk with Peter J. Wosh
Author talk by Peter J. Wosh on May 5th, 2022, on his book, "Murder on the Mountain: crime, passion, and punishment in gilded age New Jersey.
Mr. Melvin J. Collier, RWWL AUC, June 2011
This video is a conversation with Mr. Melvin J. Collier. Mr. Collier talks about his book, "From Mississippi to Africa: A Journey of Discovery". Daniel Le, AUC Woodruff Library, is the interviewer
A Tripartite Post-Recession Rebalancing
In this latest Advance & Rutgers Report, entitled “A Tripartite Post-Recession Rebalancing,” Dean James W. Hughes and Professor Joseph J. Seneca deliver an incisive assessment of the current market conditions and obstacles in the path of our economic recovery. They offer a statistical cautionary tale that the private and public sector need to hear and acknowledge in order for the economy to make continued progress.This report was published as Issue Paper Number 7, November 2011, in Advance & Rutgers Report
Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of meson decays to J/ψη and J/ψη′
First evidence of the B 0 → J / ψ ω decay is found and the B s 0 → J / ψ η and B s 0 → J / ψ η ′ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb -1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The branching fractions of these decays are measured relative to that of the B 0 → J / ψ ρ 0 decay:frac(B (B 0 → J / ψ ω), B (B 0 → J / ψ ρ 0)) = 0.89 ± 0.19 (stat) - 0.13 + 0.07 (syst),frac(B (B s 0 → J / ψ η), B (B 0 → J / ψ ρ 0)) = 14.0 ± 1.2 (stat) - 1.5 + 1.1 (syst) - 1.0 + 1.1 (frac(f d, f s)),frac(B (B s 0 → J / ψ η ′), B (B 0 → J / ψ ρ 0)) = 12.7 ± 1.1 (stat) - 1.3 + 0.5 (syst) - 0.9 + 1.0 (frac(f d, f s)), where the last uncertainty is due to the knowledge of f d / f s, the ratio of b-quark hadronization factors that accounts for the different production rate of B 0 and B s 0 mesons. The ratio of the branching fractions of B s 0 → J / ψ η ′ and B s 0 → J / ψ η decays is measured to befrac(B (B s 0 → J / ψ η ′), B (B s 0 → J / ψ η)) = 0.90 ± 0.09 (stat) - 0.02 + 0.06 (syst)
Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia: results of a randomised, controlled trial.
BACKGROUND AND OBJECTIVE:
Sugammadex, a modified gamma-cyclodextrin, is a selective relaxant-binding agent designed to reverse the effects of the steroidal neuromuscular blocking agents rocuronium or vecuronium. This study compared the efficacy of sugammadex and neostigmine for reversal of neuromuscular blockade induced by rocuronium for facilitating elective surgery.
METHODS:
This randomised, multicentre, parallel-group trial included 98 adult patients. Patients received intravenous propofol for induction followed by sevoflurane maintenance anaesthesia. Neuromuscular blockade was monitored using acceleromyography and a train-of-four (TOF) mode of stimulation. Patients were randomly allocated to receive sugammadex 2.0 mg kg(-1) or neostigmine 50 microg kg (-1) (with glycopyrrolate 10 microg kg(-1)) at reappearance of the second response of the TOF (mean 16% twitch height of first response) after the last dose of rocuronium. Safety was evaluated by assessing adverse events, laboratory variables and vital signs.
RESULTS:
Time to recovery of the TOF ratio of 0.9 after sugammadex compared with neostigmine was significantly shorter (P < 0.0001), being 1.5 versus 18.6 min (geometric means). Predictability of response was greater with sugammadex than neostigmine: with 98% of sugammadex patients versus 11% of neostigmine patients recovering to a TOF ratio of 0.9 within 5 min. There were no clinical events related to residual neuromuscular blockade or reoccurrence of blockade. Serious adverse events were observed in two sugammadex-treated patients and in three neostigmine-treated patients, respectively, but none were considered related to study drugs.
CONCLUSION:
Sugammadex achieved significantly faster recovery of neuromuscular function after rocuronium to a TOF ratio of 0.9 compared with neostigmine
The vanishing author in computer-generated works: a critical analysis of recent Australian case law
Abstract
The use of software is ubiquitous in the creation of many copyright works, yet the requirement in copyright law that every work have a human author who engages in independent intellectual effort means that its use may prevent copyright subsistence. Several recent Australian cases have refocused attention on authorship as an essential criterion of copyright subsistence, and these cases suggest that much computer-produced output may be authorless and thus lack copyright protection. This article, the first in a two-part series, analyses how each case deals with the question of authorship of computer-produced works and why the use of software diminishes copyright protection for a significant number of computer-generated works. The article critiques the application of conventional notions of human authorship developed in the pre-computer age to modern productions and suggests alternative approaches to authorship that satisfy both the major objectives of copyright policy and the need to adapt to the computer age. The article argues that, without a broader judicial approach to authorship of computer-generated works, Parliament must remedy the lacuna in protection for these ‘authorless’ works. Possible solutions for reform are suggested. In a forthcoming article, the author comprehensively examines those reform proposals
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