1,720,966 research outputs found
ANTIOXIDANT ACTIVITY OF METHANOL EXTRACT NATUNA MARINE SPONGE (PORIFERA) WITH DPPH METHODE
Full text linkObjective: Natuna sponge is a marine animal that contains a wide range of secondary metabolites that can be utilized in the field of pharmacy. The research aims to test the phytochemical content and antioxidant activity of the Natuna methanol marine sponge extract. Sample extraction is done by the maceration method with methanol solvent.
Methods: Phytochemical tests include alkaloid testing, flavonoids, steroids, saponins, and tannins. Test antioxidant activity using the immersion DPPH method (1.1-diphenyl-2-picryl hydroxyl) measured absorption at a wavelength of 517 nm.
Results: The phytochemical test results showing the sponge of Natuna contain secondary metabolites including alkaloids, flavonoids, steroids, saponins, and tannins.
Conclusion: This Natuna sponge methanol extract has an antioxidant activity that is very strong with an IC50 value of 52.91 ppm, and the comparator used is Vitamin C with an IC50 value of 43,51 ppm
Hari Farmasis Sedunia: Penyuluhan Informasi Obat dan Pembagian Masker Gratis di Kampung Seraya Batu Ampar Batam: World Pharmacists Day: Drug Information Services and Free Mask Distribution in Seraya Village, Batu Ampar, Batam City
No full textWorld Pharmacists day is an annual event to commemorate World Pharmacist Day. One form of our participation in the Bachelor of Pharmacy STIKes study program Mitra Bunda Persada Batam in celebrating the World Pharmacist Day is to hold information on drug information as well as free mask distribution for residents in Seraya Batu Ampar village. This free mask distribution is because in recent months there have been forest fires that have caused air pollution in Batam City. The World Pharmacist Day program was held in September 2015 with Drug Information Services for residents and free mask distribution for motorists on the streets around the village while. The program began in the morning, which started with a question and answers from the residents about the drugs they were using, then continued with the distribution of masks. This event was very well received by the residents because it was scarce for an event like this to be done. Our Pharmacy Study Program is very enthusiastic about being able to provide community servic
Effect of Drug Information Service Quality Patient Satisfaction City Pharmacy X Padang
Full text linkPenelitian ini ditujukan untuk menganalisis pengaruh kualitas pelayanan informasi obat berdasarkan dimensi kualitas jasa yang terdiri dari variabel-variabel reliability (kehandalan), responsiveness (cepat tanggap), assurance (jaminan), empathy (empati) dan tangible (nyata) serta kepuasan pasien. Variabel-variabel tersebut digunakan untuk menganalisis pengaruh kualitas pelayanan informasi obat terhadap kepuasan pasien di Apotek X Kota Padang. Sampel yang digunakan dalam penelitian ini adalah 100 responden, teknik pengambilan sampel ditentukan dengan purposive sampling. Metode analisis yang digunakan adalah metode regresi linier berganda dengan menggunakan uji-t, uji-F dengan taraf signifikansi α = 5%, serta uji- R2 dengan program SPSS versi 17,0. Hasil dari penelitian menunjukkan kualitas pelayanan informasi obat dimensi reliability, responsiveness, assurance , empathy dan tangible bersama-sama memberikan pengaruh signifikan terhadap kepuasan pasien Apotek X Kota Padang sebesar 16,7% (F-hitung = 3,771, p=0,004). Dimensi yang paling memuaskan pasien adalah dimensi yang mempunyai gap paling kecil, yaitu dimensi emphaty (-0.90).This study was aimed to analyze the influence of the drug information service quality based on the dimensions of service quality that consists of variables: reliability (reliability), responsiveness (quick response), assurance (security), empathy (empathy) and tangible (real) as well as patient satisfaction. These variables are used to analyze the impact of service quality drug information on patient satisfaction in the Pharmacy X Padang. The sample used in this study was 100 respondents, the sampling technique was determined by purposive sampling. The analytical method used was multiple linear regression method using t-test, F-test with a significance level α = 5%, as well as test-R2, using the SPSS program version 17.0. Results of the study showed the drug information service quality dimensions of reliability, responsiveness, assurance, empathy and tangible together have a significant effect on Pharmacy X Padang’s patient satisfaction by 16.7% (F-test = 3.771, p = 0.004), The most satisfying dimension for patients is the dimension that has the smallest gap, which is emphaty dimension (-0.90)
ANALISIS KUANTITATIF KANDUNGAN MERKURI (Hg) PADA PRODUK BEDAK PEMUTIH YANG BEREDAR DI KOTA BATAM: QUANTITATIVE DETERMINATION OF MERCURY (Hg) LEVELS IN WHITENING POWDERS DISTRIBUTED IN BATAM CITY
Full text linkCosmetics are ingredients or mixtures of ingredients to be used on parts of the human body with the intention of cleansing, protecting to keep it in good condition and can play a role in healing and skin care. Facial cosmetic products that are currently often used are powder. There are various forms of powder, one of which is whitening powder which is widely discussed not only the product that floods the market, but also because of the impact of using the product which is able to whiten and brighten the face in a very short time. The content contained in these products also varies, some are formulated safe to use and dangerous when used. One of them is that mercury (Hg) is usually added intentionally or not very unjustified because it will be in direct contact with the skin and can be toxic. This study aims to identify the content of Mercury (Hg) in whitening surgery circulating in Batam City using the FIMS (Flow Injection Mercury System) test method. The results of research conducted on 10 whitening powder samples obtained mercury (Hg) levels with the largest average value, namely in the Px sample code with a value of 0.924 mg/kg, while the smallest average value was in the Lv sample code with a value of 0.021 mg/kg. In the test, there is a mercury content, but no one exceeds the maximum limit for cosmetics set by BPOM, which in BPOM regulations regarding metal contamination requirements in cosmetics containing mercury (Hg) is no more than 1 mg/kg, so it is safe to use.
Keywords: Cosmetics, whitening powder, mercury, FIMS (Flow Injection Mercury System), HgKosmetika merupakan bahan atau campuran bahan untuk dipergunakan pada bagian badan manusia dengan maksud untuk membersihkan, melindungi supaya tetap dalam keadaan baik dan dapat berperan dalam penyembuhan dan perawatan kulit. Produk kosmetik wajah yang saat ini sering digunakan adalah bedak. Ada berbagai macam bentuk bedak, salah satunya adalah bedak whitening yang ramai diperbincangkan bukan hanya produknya yang membanjiri pasaran, tetapi juga karena dampak dari pemakaian produk tersebut yang mampu memutihkan dan mencerahkan wajah dalam waktu sangat singkat. Kandungan yeng terdapat pada produk tersebut pun beragam, ada yang di formulasikan aman untuk digunakan maupun yang berbahaya saat digunakan. Salah satunya adalah merkuri (Hg) biasanya ditambahkan sengaja atau tidak sangat tidak dibenarkan karena akan kontak langsung dengan kulit dan dapat bersifat racun. Penelitian ini bertujuan untuk mengidentifikasi kandungan Merkuri (Hg) pada bedah whitening yang beredar di Kota Batam dengan menggunakan metode uji FIMS (Flow Injection Mercury System). Hasil penelitian yang dilakukan pada 10 sampel bedak whitening diperoleh kadar merkuri (Hg) dengan rata-rata nilai terbesar yaitu pada kode sampel Px dengan nilai sebesar 0,924 mg/kg, sedangkan rata-rata nilai terkecil yaitu pada kode sampel Lv dengan nilai sebesar 0,021 mg/kg. Pada pengujian tersebut terdapat kandungan merkuri, namun tidak ada yang melebihi batas maksimum untuk kosmetik yang telah ditetapkan oleh BPOM, yang mana dalam peraturan BPOM tentang persyaratan cemaran logam pada kosmetik yang mengandung merkuri (Hg) tidak lebih dari 1 mg/kg, sehingga aman untuk digunakan
Formulasi dan Evaluasi Mutu Fisik Tablet Hisap Ekstrak Herba Meniran (Phyllanthus Niruri L.) dengan Bahan Pengisi Sukrosa-Manitol: Meniran (Phyllantus Niruri L.) Herb Extract Lozenges with Sucrose-Mannitol as a Filler: Formulation and Physical Quality Evaluation
No full textMeniran merupakan salah satu tumbuhan yang sejak lama sudah dimanfaatkan sebagai obat tradisional untuk mengobati berbagai macam penyakit. Penggunaan meniran sebagai obat tradisional saat ini masih dalam bentuk sediaan yang kurang praktis yaitu dengan cara direbus maupun diseduh. Tujuan: Penelitian ini bertujuan untuk mendapatkan formulasi sediaan tablet hisap ekstrak herba meniran dengan mutu fisik yang baik. Metode: Tablet hisap dibuat dengan metode granulasi basah dengan variasi konsentrasi sukrosa-manitol F1=1:5, F2=1:6, dan F3=1:7 dilanjutkan dengan evaluasi mutu fisik tablet hisap. Hasil: Hasil evaluasi granul ketiga formula memenuhi persyaratan uji kadar air, uji waktu alir, uji sudut diam, dan uji kompresibilitas yang baik. Hasil evaluasi tablet hisap ketiga formula memenuhi persyaratan organoleptis, keseragaman ukuran, keseragaman bobot, kekerasan, dan waktu hancur yang baik. Sedangkan uji kerapuhan F2 dan F3 belum memenuhi persyaratan. Kesimpulan: Tablet hisap ekstrak herba meniran (Phyllanthus niruri L.) dengan konsentrasi sukrosa-manitol (1:5) memiliki kriteria yang baik sebagai tablet hisap dengan kekerasan tablet 9 kg, kerapuhan 0,44%, dan waktu hancur 28 menit
Studi Farmakovigilans Pengobatan MDR-TB pada Pasien Rawat Jalan di RSUD Embung Fatimah Kota Batam Tahun 2020: Study of MDR-TB Treatment Pharmacovigilans in Outpatients at Embung Fatimah Hospital Batam City in 2020
No full textPharmacovigilance is a science related to collecting, detecting, monitoring, assessing, and preventing side effects of pharmaceutical products. The design of this research is retrospectively descriptive. To understand the characteristics of MDR-TB patients and the side effects of the drug that MDR-TB patients feel. The research was conducted between January 2020 – June 2020. The research was conducted at Embung Fatimah Hospital. The number of confirmed patients with MDR TB was 24 patients, 9 male (37.5%) and 15 women (62.5%); the average MDR-TB patient aged 26-45 years (54.20%), Batu Aji (45.83%) be the place most exposed to MDR-TB with a social history of smoking, drugs, and alcohol. The results showed patients who experienced 41.7% anorexia side effects, 100% nausea, 100% vomiting, reduced appetite by 37.5%, 79.2% pain at the injection site, 79.2% joint pain, 58.3% reduced hearing and 25% vertigo. In conclusion, most side effects are nausea and vomiting
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Formulasi dan Uji Aktivitas Antibakteri Krim Ekstrak Etanol Rumput Laut Cokelat (Sargassum polycystum) Terhadap Bakteri Propionibacterium acnes : Formulation and Antibacterial Activity Test of Brown Seaweed (Sargassum polycystum) Ethanol Extract Cream Against Bacteria Propionibacteria acnes
No full textPenyakit kulit yang umum terjadi adalah jerawat. Jerawat dapat timbul akibat infeksi bakteri Propionibacterium acnes. Salah satu bahan alam yang dapat dijadikan obat untuk jerawat adalah tumbuhan rumput laut cokelat (Sargassum polycystum). Penelitian ini bertujuan untuk memformulasikan ekstrak rumput laut cokelat menjadi sediaan krim antibakteri terhadap bakteri Propionibacterium acnes. Ekstrak rumput laut cokelat didapatkan melalui proses maserasi menggunakan etanol 96%. Pembuatan formulasi krim menggunakan variasi konsentrasi 20%, 25%, dan 50%. Evaluasi krim terdiri dari organoleptis, homogenitas, pH, tipe emulsi, viskositas, daya sebar, daya lekat, dan iritasi. Pengujian antibakteri ekstrak rumput laut cokelat dan krim terhadap bakteri Propionibacterium acnes dilakukan dengan metode difusi sumuran, kemudian diameter zona hambat dianalisis mengggunakan uji One Way Anova. Hasil penelitian menunjukkan bahwa krim ekstrak rumput laut cokelat telah memenuhi syarat krim yang baik. Ekstrak rumput laut cokelat dan krim dapat menghambat pertumbuhan bakteri Propionibacterium acnes tertinggi pada konsentrasi 50% diperoleh rata-rata diameter zona hambat masing-masing yaitu 17,9 mm (kuat) dan 15,3 mm (kuat) dengan nilai yang signifikan sebesar p<0,05 melalui uji One Way ANOVA. Ekstrak rumput laut cokelat dapat diformulasikan menjadi bentuk krim yang memiliki aktivitas antibakteri terhadap bakteri Propionibacterium acnes dengan daya hambat kuat pada konsentrasi 50%
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