35 research outputs found
Viewing socio-affective stimuli increases connectivity within an extended default mode network
Empathy is an essential ability for prosocial behavior. Previous imaging studies identified a number of brain regions implicated in affective and cognitive aspects of empathy. In this study, we investigated the neural correlates of empathy from a network perspective using graph theory and beta-series correlations. Two independent data sets were acquired using the same paradigm that elicited empathic responses to socioaffective stimuli. One data set was used to define the network nodes and modular structure, the other data set was used to investigate the effects of emotional versus neutral stimuli on network connectivity. Emotional relative to neutral stimuli increased connectivity between 74 nodes belonging to different networks. Most of these nodes belonged to an extended default mode network (eDMN). The other nodes belonged to a cognitive control network or visual networks. Within the eDMN, posterior STG/TPJ regions were identified as provincial hubs. The eDMN also showed stronger connectivity to the cognitive control network encompassing lateral PFC regions. Connector hubs between the two networks were posterior cingulate cortex and ventrolateral PFC. This stresses the advantage of a network approach as regions similarly modulated by task conditions can be dissociated into distinct networks and regions crucial for network integration can be identified.</p
Single Channel Optimization for an Endoscopic Time-of-Flight Positron Emission Tomography Detector
Performance of VATA64HDR16 ASIC for medical physics applications based on continuous crystals and SiPMs
[EN] Detectors based on Silicon Photomultipliers (SiPMs) coupled to continuous crystals are being tested in medical physics applications due to their potential high resolution and sensitivity. To cope with the high granularity required for a very good spatial resolution, SiPM matrices with a large amount of elements are needed. To be able to read the information coming from each individual channel, dedicated ASICs are employed. The VATA64HDR16 ASIC is a 64-channel, charge-sensitive amplifier that converts the collected charge into a proportional current or voltage signal. A complete assessment of the suitability of that ASIC for medical physics applications based on continuous crystals and SiPMs has been carried out. The input charge range is linear from 20 pC up to 55 pC. The energy resolution obtained at 511 keV is 10% FWHM with a LaBr3 crystal and 16% FWHM with a LYSO crystal. A coincidence timing resolution of 24 ns FWHM is obtained with two LYSO crystals.This work was supported in part by the European Commission's 7th Framework Programme through the ENVISION project (G. A. num 241851), by the Spanish Ministerio de Economia y Competitividad (FPA2014-53599-R), the UVEG (UV-INV-PRECOMP12-80755) and the Generalitat Valenciana (GV/2013/133 and GVISIC/2012/020). Group members are supported by Ramon y Cajal, UVEG Atraccio de Talent and Generalitat Valenciana contracts.Barrio-Toala, John;Etxebeste, A.;Lacasta, C.;Muñoz, E.;Oliver-Guillén, José Francisco;Solaz, C.;Llosá, G. (2015). Performance of VATA64HDR16 ASIC for medical physics applications based on continuous crystals and SiPMs. Journal of Instrumentation. 10. https://doi.org/10.1088/1748-0221/10/12/P12001S10Llosá, G., Barrio, J., Lacasta, C., Bisogni, M. G., Guerra, A. D., Marcatili, S., Barrillon, P., Bondil-Blin, S., de la Taille, C., & Piemonte, C. (2010). Characterization of a PET detector head based on continuous LYSO crystals and monolithic, 64-pixel silicon photomultiplier matrices. Physics in Medicine and Biology, 55(23), 7299-7315. https://doi.org/10.1088/0031-9155/55/23/008Seifert, S., van Dam, H. T., Huizenga, J., Vinke, R., Dendooven, P., Löhner, H., & Schaart, D. R. (2012). Monolithic LaBr3:Ce crystals on silicon photomultiplier arrays for time-of-flight positron emission tomography. Physics in Medicine and Biology, 57(8), 2219-2233. https://doi.org/10.1088/0031-9155/57/8/2219Powolny, F., Auffray, E., Brunner, S. E., Garutti, E., Goettlich, M., Hillemanns, H., Jarron, P., Lecoq, P., Meyer, T., Schultz-Coulon, H. C., Shen, W., & Williams, M. C. S. (2011). Time-Based Readout of a Silicon Photomultiplier (SiPM) for Time of Flight Positron Emission Tomography (TOF-PET). IEEE Transactions on Nuclear Science, 58(3), 597-604. https://doi.org/10.1109/tns.2011.2119493Blin, S., Barrillon, P., & de La Taille, C. (2010). MAROC, a generic photomultiplier readout chip. IEEE Nuclear Science Symposuim & Medical Imaging Conference, 1690-1693. https://doi.org/10.1109/nssmic.2010.5874062Raux, L., Callier, S., Conforti di Lorenzo, S., Dulucq, F., de La Taille, C., Martin-Chassard, G., & Seguin-Moreau, N. (2012). SPIROC: Design and performance of a dedicated very front-end for an ILC prototype Hadronic Calorimeter with SiPM. 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC), 557-561. https://doi.org/10.1109/nssmic.2012.6551170Argentieri, A., Corsi, F., Foresta, M., Marzocca, C., & Del Guerra, A. (2011). Design and characterization of CMOS multichannel front-end electronics for silicon photomultipliers. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 652(1), 516-519. https://doi.org/10.1016/j.nima.2010.08.067Meier, D., Mikkelsen, S., Talebi, J., Azman, S., Mahlum, G., & Patt, B. E. (2010). An ASIC for SiPM/MPPC readout. IEEE Nuclear Science Symposuim & Medical Imaging Conference, 1653-1657. https://doi.org/10.1109/nssmic.2010.5874056Rolo, M. D., Bugalho, R., Gonçalves, F., Mazza, G., Rivetti, A., Silva, J. C., Silva, R., & Varela, J. (2013). TOFPET ASIC for PET applications. Journal of Instrumentation, 8(02), C02050-C02050. https://doi.org/10.1088/1748-0221/8/02/c02050Cabello, J., Barrillon, P., Barrio, J., Bisogni, M. G., Del Guerra, A., Lacasta, C., Rafecas, M., Saikouk, H., Solaz, C., Solevi, P., de La Taille, C., & Llosá, G. (2013). High resolution detectors based on continuous crystals and SiPMs for small animal PET. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 718, 148-150. https://doi.org/10.1016/j.nima.2012.08.094Development of a three layer Compton telescope prototype based on continuous LaBr<inf>3</inf> crystals and Silicon Photomultipliers. (2013). 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC), 1-3. https://doi.org/10.1109/nssmic.2013.6829049Data acquisition system for the readout of SiPM arrays. (2013). 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC), 1-4. https://doi.org/10.1109/nssmic.2013.6829735Bagliesi, M. G., Avanzini, C., Bigongiari, G., Cecchi, R., Kim, M. Y., Maestro, P., Marrocchesi, P. S., & Morsani, F. (2011). A custom front-end ASIC for the readout and timing of 64 SiPM photosensors. Nuclear Physics B - Proceedings Supplements, 215(1), 344-348. https://doi.org/10.1016/j.nuclphysbps.2011.04.049Llosá, G., Barrio, J., Cabello, J., Crespo, A., Lacasta, C., Rafecas, M., Callier, S., de La Taille, C., & Raux, L. (2012). Detector characterization and first coincidence tests of a Compton telescope based on LaBr3 crystals and SiPMs. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 695, 105-108. https://doi.org/10.1016/j.nima.2011.11.04
Information retrieval as a basis for understanding Pseudallescheria and Scedosporium
DermatologyMycologySCI(E)1EDITORIAL MATERIAL,SI1-45
Бронхиальная астма, вызванная ингаляцией токсико-аллергенных аэрозолей поливинилхлорида
Bronchial asthma related to inhalation of toxico-allergic aerosols of polyvinyl chloride.Бронхиальная астма, вызванная ингаляцией токсико-аллергенных аэрозолей поливинилхлорида
Production of Mesons with Dijets in Deep-Inelastic Scattering at HERA
31 pages, 7 figures - Subm. to Eur. Phys. J. CInclusive D* production is measured in deep-inelastic ep scattering at HERA with the H1 detector. In addition, the production of dijets in events with a D* meson is investigated. The analysis covers values of photon virtuality 2< Q^2 <=100 GeV^2 and of inelasticity 0.05<= y <= 0.7. Differential cross sections are measured as a function of Q^2 and x and of various D* meson and jet observables. Within the experimental and theoretical uncertainties all measured cross sections are found to be adequately described by next-to-leading order (NLO) QCD calculations, based on the photon-gluon fusion process and DGLAP evolution, without the need for an additional resolved component of the photon beyond what is included at NLO. A reasonable description of the data is also achieved by a prediction based on the CCFM evolution of partons involving the k_T-unintegrated gluon distribution of the proton
Production of Mesons with Dijets in Deep-Inelastic Scattering at HERA
31 pages, 7 figures - Subm. to Eur. Phys. J. CInclusive D* production is measured in deep-inelastic ep scattering at HERA with the H1 detector. In addition, the production of dijets in events with a D* meson is investigated. The analysis covers values of photon virtuality 2< Q^2 <=100 GeV^2 and of inelasticity 0.05<= y <= 0.7. Differential cross sections are measured as a function of Q^2 and x and of various D* meson and jet observables. Within the experimental and theoretical uncertainties all measured cross sections are found to be adequately described by next-to-leading order (NLO) QCD calculations, based on the photon-gluon fusion process and DGLAP evolution, without the need for an additional resolved component of the photon beyond what is included at NLO. A reasonable description of the data is also achieved by a prediction based on the CCFM evolution of partons involving the k_T-unintegrated gluon distribution of the proton
Events with an isolated lepton and missing transverse momentum and measurement of W production at HERA
Events with high energy isolated electrons, muons or tau leptons and missing transverse momentum are studied using the full e ± p data sample collected by the H1 experiment at HERA, corresponding to an integrated luminosity of 474 pb -1. Within the Standard Model, events with isolated leptons and missing transverse momentum mainly originate from the production of single W bosons. The total single W boson production cross section is measured as 1.14±0.25 (stat.)±0.14 (sys.) pb, in agreement with the Standard Model expectation. The data are also used to establish limits on the WW γ gauge couplings and for a measurement of the W boson polarisation
