70 research outputs found
Current problems and possible solutions in the treatment of nasopharyngeal carcinoma in Indonesia
No full textDe zorg voor patiënten met nasopharynxkanker in Indonesië is op dit moment erg teleurstellend. Maarten Wildeman noemt in zijn promotie verschillende oplossingen om de zorg te verbeteren zoals de implementatie van een datamanagementsysteem, opleiding van huisartsen voor een betere bewustwording en kennis van nasopharynxcarcinoom en introductie van nieuwe behandelingsmethoden. Nasopharynxcarcinoom, een kwaadaardige tumor in de keel-neusholte, is zeldzaam in de westerse wereld, maar komt veel voor in Indonesië. De ziekte is goed te genezen met radiotherapie in combinatie met chemotherapie, maar in Indonesië zijn de behandelresultaten teleurstellend. Wildeman onderzocht de mogelijke oorzaken van de teleurstellende behandelresultaten. Tevens testte hij het effect van training voor huisartsen, tijdens de training kregen huisartsen uitleg zodat ze in de toekomst patiënten sneller zullen verwijzen
Book Review: Sara Wakefield and Christopher Wildeman, Children of the Prison Boom. Mass Incarceration and the Future of American Inequality. New York: Oxford University Press, 2014, 248 pp.
No full textThe article reviews the book of Sarah Wakefield and Christopher Wildeman on the Children of Inmates. The author tries to focus on the necessity of intertwine sociological research with criminological aspects
Can Oslo’s failed aid model be laid to rest?
No full textOverview: Since the signing of the 1993 Oslo Declaration of Principles, the donor community has invested more than $23 billion into “peace and development” in the Occupied Palestinian Territory (OPT), making it one of the highest per capita recipients of non-military aid in the world. However, aid has not brought peace, development, or security for the Palestinian people, let alone justice. Al-Shabaka Guest Author Jeremy Wildeman and Program Director Alaa Tartir examine the origins of the present aid-for-peace model as well as its effects on socio-economic conditions and pull together the many critiques of the Oslo economic model. The authors argue that donors are reinforcing failed past patterns associated with the so-called peace dividends model while making only cosmetic changes to their engagement. Indeed, donors do not appear ready to change an approach dominated by policy “instrumentalists” who ignore and reject outcomes that do not match their pre-determined values instead of upholding international law on Palestinian rights and international development principles that strive to “do no harm.” They underscore the alarming possibility that the Oslo aid model may serve too many interests to be dismantled and conclude with an assessment of what will be needed for change
Towards Quantitative Spatio-Temporal Gene Expression Measurements in Mice
No full textIn this project we tried to answer the question whether it is possible to obtain in vivo quantitative spatiotemporal gene expression data of mice, by making use of the GFP protein and Biofluorence Imaging. The research was driven by a more specific question, being whether it is possible to detect if metastasis to the bone has occurred in cancer progression studies, using GFP cancel cell lines, i.e cancer cells that produce Green Fluorescent Proteins (GFP), at a continuous known rate. We tried to give generic answers by researching the following two subquestions. 1.) Is it possible to register a 3D mouse atlas to 2D Bioluminescense or Fluorescence photographs, based on only those photographs? 2.) Can we make qualitative statements on the location of gene expression, after registration with an atlas? The first question is covered in a paper called: 'Atlas Driven Registration of 3D Voxel Data to Multi-view Photographs Based on 3D Distance Maps.' It explains a method to register a 3D piecewise deformable mouse atlas to 2 or more photographic sideviews of a mouse. Based on a distance map that we generated from multiple backprojections of the sideview, we were able to construct an energy function that resembled a 'goodness of fit' of the registration. Comparisons were made with a gold standard and we obtained good results with our method. The second question is covered in a paper called: 'Testing for Spatial Gene Enrichment in C. Elegans Using Chronograms and a 1D Worm Atlas'. In this paper we did not focus on the registration process, because this was a straightforward procedure. With an atlas registered to an expression dataset, we applied different statistical tests to answer the question that given the atlas and the expression profile, the observed expression shows enrichment in a selected organ or not. In this paper we show that we are able to filter highly enriched signals out of our complete dataset. We further discuss the added value of our atlas since it is difficult to validate the obtained results of our tests.Electrical Engineering, Mathematics and Computer Scienc
Agonizing Identity in Mental Health Law and Policy (Part I)
No full textIn this two-part paper, the author explores the significance of identity in mental health law and policy. In this as in other socio-legal domains, identity functions to consolidate dissent as well as to effect social control. The author asks: where do legal experts stand in relation to the identity categories that run so deep in this area of law and policy? More broadly, she asks: is “mental health” working on us — on the mental health disabled, legal scholars, all of us — in ways that are impairing our capacity for social justice? In the first part of the paper, the author considers the Foucauldian exhortation to undertake a “critical ontology of ourselves” and asks what it would mean to take this curious exhortation personally, with regard to one’s mental health. In the second part, which will appear in the next issue of the Dalhousie Law Journal, she builds out from these insights toward a political taxonomy of mental health identities
Short-term effect of different teaching methods on nasopharyngeal carcinoma for general practitioners in Jakarta, Indonesia
No full textIn Indonesia, Nasopharyngeal Carcinoma (NPC) is the most frequent cancer of the head and neck region. At first presentation in the hospital most patients already have advanced NPC. Our previous study showed that general practitioners (GPs) working in Yogyakarta, Indonesia lack the knowledge necessary for early detection of NPC. By providing training on early symptoms of NPC we hope that the diagnosis and referral will occur at an earlier stage. Here we assess the current NPC knowledge levels of GPs in Jakarta, evaluate improvement after training, compare the effectiveness of two training formats, and estimate the loss of recall over a two week period.Maarten A. Wildeman, Renske Fles, Marlinda Adham, Ika D. Mayangsari, Ilse Luirink, Mara Sandberg, Andrew D. Vincent, Faiziah Fardizza, Zanil Musa, Armiyanto, Jaap M. Middeldorp, Geerten Gerritsen, Ronny Suwanto, I. Bing Ta
Can an online clinical data management service help in improving data collection and data quality in a developing country setting?
No full textBackground: Data collection by Electronic Medical Record (EMR) systems have been proven to be helpful in data collection for scientific research and in improving healthcare. For a multi-centre trial in Indonesia and the Netherlands a web based system was selected to enable all participating centres to easily access data. This study assesses whether the introduction of a Clinical Trial Data Management service (CTDMS) composed of electronic Case Report Forms (eCRF) can result in effective data collection and treatment monitoring. Methods: Data items entered were checked for inconsistencies automatically when submitted online. The data were divided into primary and secondary data items. We analysed both the total number of errors and the change in error rate, for both Primary and Secondary items, over the first five month of the trial. Results: In the first five months 51 patients were entered. The Primary data error rate was 1.6%, whilst that for Secondary data was 2.7% against acceptable error rates for analysis of 1% and 2.5% respectively. Conclusion: The presented analysis shows that after five months since the introduction of the CTDMS the Primary and Secondary data error rates reflect acceptable levels of data quality. Furthermore, these error rates were decreasing over time. The digital nature of the CTDMS, as well as the online availability of that data, gives fast and easy insight in adherence to treatment protocols. As such, the CTDMS can serve as a tool to train and educate medical doctors and can improve treatment protocols.Maarten A Wildeman, Jeroen Zandbergen, Andrew Vincent, Camelia Herdini, Jaap M Middeldorp, Renske Fles, Otilia Dalesio, Emile van der Donk, I Bing Ta
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Agonizing Identity in Mental Health Law and Policy (Part II):A Political Taxonomy of Psychiatric Subjectification
No full textThis is the second part of a two-part essay exploring the function of identity in mental health law and policy or more broadly the function of identity in the politics of mental health. Part one began with the Foucauldian exhortation to undertake a critical ontology of ourselves, and adopted the methodology of autoethnography to explore the construction or constructedness of the authors identity as an expert working in the area of mental health law and policy. That part concluded with a gesture of resistance to identification on one or the other side of the mental health/ illness divide (the divide of reason and madness), affirming instead an aspiration to carve out a space of contemplation-or rather multiple spaces: fleeting, episodic manifestations of what the author terms spectral identity -supportive of reflection on the relational determinants of one\u27s position along a continuum of shared vulnerabilities and capacities, shifting over time and across bio-psychosocial settings in defiance of simplistic binary categories. Part two builds out from these insights toward a political taxonomy of mental health identities. As such it deepens its engagement with the core question raised in part one: namely is mental health working on us-on the mental health disabled, legal scholars, all of us-in ways that are impairing our capacity for social justice
The Aerial Letter
No full textFront Cover -- About the Author -- Title Page -- Copyright -- Dedication -- Contents -- Saying the Unsayable-Susan Hawthorne -- Translator's Introduction-Marlene Wildeman -- Preface 2020 -- Preface 1988 -- Turning-Platform -- Coincidence -- The Aerial Letter -- Critical Appreciation -- Synchrony -- From Radical to Integral -- Kind Skin My Mind -- A Captivating Image -- Lesbians of Lore -- Access to Writing: Rites of Language -- Intercepting What's Real -- Certain WordsDescription based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Agonizing Identity in Mental Health Law and Policy (Part II): A Political Taxonomy of Psychiatric Subjectification
No full textThis is the second part of a two-part essay exploring the function of identity in mental health law and policy, or more broadly, the function of identity in the politics of mental health. Part one began with the Foucauldian exhortation to undertake a “critical ontology of ourselves,” and adopted the methodology of autoethnography to explore the construction or constructedness of the author’s identity as an expert working in the area of mental health law and policy. That part concluded with a gesture of resistance to identification on one or the other side of the mental health/ illness divide (the divide of reason and madness), affirming instead an aspiration to carve out a space of contemplation — or rather multiple spaces: fleeting, episodic manifestations of what the author terms “spectral identity” — supportive of reflection on the relational determinants of one’s position along a continuum of shared vulnerabilities and capacities, shifting over time and across bio-psychosocial settings in defiance of simplistic binary categories. Part two builds out from these insights toward a political taxonomy of mental health identities. As such it deepens its engagement with the core question raised in part one: namely, is “mental health” working on us — on the mental health disabled, legal scholars, all of us — in ways that are impairing our capacity for social justice
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