698 research outputs found
Dispiro-4-bromobenzylaminophosphazenes: Synthesize reactions, spectroscopic properties, crystal structures, biological and cytotoxic activities
No full text257th National Meeting of the American-Chemical-Society (ACS) -- MAR 31-APR 04, 2019 -- Orlando, FLOzgur, mehtap/0000-0002-6237-8522; Aydin, Betul/0000-0002-9092-1350…Amer Chem So
Monocentric Relationship Management (MRM) and Mcorebrain™: Defining the Single AI Paradigm Beyond CRM (Version 3.0)
No full textThis concept note introduces Monocentric Relationship Management (MRM) — an AI-native paradigm defining a single accountable AI controller that autonomously governs the entire relationship lifecycle beyond CRM.
Unlike traditional enterprise architectures that fragment intelligence across sales, marketing, pricing, contract management, credit decisioning, billing, entitlements, compliance, and service, MRM unifies them under one closed-loop cognitive system.
The framework integrates autonomy and governance through policy-as-code, human-in-the-loop oversight, and continuous learning. It reframes relationship management as an integrated control problem, where predictive and prescriptive intelligence operate within explicit safety, ethical, and compliance boundaries.
Version 3.0 expands the foundational model by introducing the Mcorebrain™ — the autonomous cognitive nucleus of MRM that interprets natural-language prompts, validates them against policy constraints, and autonomously constructs operational systems, including data models, logic, and user interfaces.
This release defines a prompt-driven generation model, connecting business intent, governance policy, and system execution in one unified, accountable framework.
Previous version:
Javanbakht, A.H. (2025). Monocentric Relationship Management: Defining the Single AI Paradigm Beyond CRM (v2.0). DOI: 10.5281/zenodo.17209903
License: Creative Commons Attribution 4.0 International (CC BY 4.0)
Author: Aydin Habibi Javanbakht — Berlin, Germany
DOI (this version): 10.5281/zenodo.1733476
Characterization of the Welding Zone of Automotive Sheets of Different Thickness (DP600 and DP800) Joined by Resistance Spot Welding
No full textAutomotive industry in recent years, has gained great importance. In line with this, DP600 and DP800 dual-phase steels and the electrical resistance spot welding method were used in the study. During the experimental trials, different welding currents (6, 7, and 8 kA) were selected and all other welding parameters were kept constant. The effects of the welding parameters on microstructure, hardness, tensile-shear, and cross-tensile strength were analyzed. In the phase measurements, 27.06-29.97% martensite and 70.73-73.85% ferrite phases were found. When the hardness values in the HAZ regions were examined, it was seen that the highest hardness values were 356 +/- 5 HV in the DP600 and 451 +/- 5 HV in the DP800 with a current intensity of 6 kA. Consequently, it was determined that tensile-shear and cross-tensile strengths had increased in parallel with the increase in the welding current and the highest values were determined as 8 kA-15.91 kN in tensile shear and 8 kA-4.91 kN in cross-tensile strength.Karabuk University [FDK-2020-2132]; BAP [FDK-2020-2132]We would like to thank Karabuk University Rectorate and the BAP Coordinator for supporting this study within the scope of the FDK-2020-2132 project
Subtype Distribution And Molecular Characterization Of Blastocystis From Hemodialysis Patients In Turkey
No full textJOURNAL OF INFECTION IN DEVELOPING COUNTRIESIntroduction: The aim of this study was to determine the Blastocystis prevalence and subtypes in hemodialysis patients in Turkey. Methodology: Eighty-four patients diagnosed with end-stage renal failure who were undergoing hemodialysis and 20 healthy volunteers were enrolled. Blastocystis presence was investigated by native-Lugol, trichrome staining, PCR using STS primers, and DNA sequencing analysis. Results: Among the stool samples from the hemodialysis patients, 9.52 (8/84) were found to be Blastocystis-positive with the native-Lugol and trichrome staining. Seven of the eight Blastocystis isolates were subtyped using STS primers. Blastocystis subtype distribution was as follows: one had ST1, two had ST2, two had ST3, two had ST3ST6, and one was not subtyped. Blastocystis positivity was detected in two healthy control (2/20, 10), one subject had ST1, and the other was not subtyped. All subtypes identified by PCR were confirmed by the sequencing analysis. In the two samples that had mixed subtypes (ST3ST6) when using the STS primers, only ST3 was detected in the sequencing analysis. Although some patients have multiple symptoms, the most common symptoms in Blastocystis positive patients were bloating (5/8), diarrhea (4/8), nausea and vomiting (2/8), and gas and weight loss (1/8). Also, only one patient had Giardia intestinalis. Conclusions: This was the first study to determine the Blastocystis subtypes in hemodialysis patients. A rare subtype, ST6, was identified in two of the patients. Thus, the ST6 infections were attributable to transmission from poultry infections. The presence of this unusual subtype suggests the need for further extensive studies of hemodialysis patients
Nurse-led support impact via a mobile app for breast cancer patients after surgery: a quasi-experimental study (step 2)
No full textBreast cancer patients may experience some health issues following surgery. Training patients about self-care plays a vital role in managing these symptoms. Mobile applications are a contemporary and appropriate approach to support patients about the potential symptoms following breast cancer surgery. This quasi-experimental study aimed to assess the impact of nurse-led support mobile application (NL-Mapp) delivered on breast cancer patients after surgery. Ninety participants were recruited, with 45 assigned to the intervention group and 45 to the control group. Subjects in the intervention group received NL-Mapp in addition to routine care, while those in the control group received only routine care over four weeks. The intervention included educational content on the postoperative period of breast cancer. Outcomes were assessed at baseline (M0), before discharge (M1), and one month after surgery (M2). The intervention group patients had significantly improved pain, affected shoulder functions, and anxiety owing to the effects of group, time, and group-time interaction. Body image and sexual adjustment were enhanced based on time and group-time interaction effects. During the follow-up period, experimental group patients experienced an improvement in body image and sexual adjustment, while those in the control group showed a decrease. This suggests that NL-Mapp may play a significant role in training breast cancer patients to manage their symptoms after surgery. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.3916444
Phosphorus-Nitrogen compounds part 47: The conventional and microwave-assisted syntheses of dispirocyclotriphosphazene derivatives with (4-fluoro/4-nitrobenzyl) pendant arms: Structural and stereogenic properties and DNA interactions
No full textWOS: 000463348300022The Cl exchange reactions of hexachlorocyclotriphosphazene, N3P3Cl6, with two equimolar amounts of N-alkyl-N'-mono(4-fluorobenzyl)diamines (1-3), FC6H4CH2NH(CH2)(n)NHR1 (n=2 and 3, R-1=CH3 or C2H5), and N-alkyl-N'-mono(4-nitrobenzyl)diamines (4 and 5), NO2C6H4CH2NH(CH2)(n)NHR1 (n= 2, R-1= CH3 or C2H5), led to the formation of the mono(4-fluorobenzyl) (1a-3a) and mono(4-nitrobenzyl) (4a and 5a) spirocyclotriphosphazenes as minor products, and trans-bis(4-fluorobenzyl) (1b-3b) and trans-bis(4-nitrobenzyl) (4b and 5b) spirocyclotriphosphazenes as major products. The bis(4-fluorobenzyl) spirocyclotriphosphazene (1b) reacted with excess pyrrolidine to give fully substituted (1c) phosphazene. The structures of the new compounds were elucidated by elemental analyses, ESI-MS, FTIR, H-1, C-13, and P-31 NMR techniques. The molecular and crystal structures of 1a, 3b and 6 were identified by single crystal X-ray crystallography. The absolute configurations of 3b and 6 were unambiguously established as SS and R respectively, using X-ray crystallographic data. On the other hand, the interactions of 1b, 1c, 3b-5b and 6 with plasmid DNA indicated that compounds 3b, 4b, and 5b caused a decrease in the mobilities and intensities of form I and form II DNA. Compounds 1b, 1c and 6 caused a double strand break of plasmid DNA. All of the tested compounds inhibited enzyme cleavage indicating compound bindings to the specific G/G and A/A nucleotides.Turkish Academy of Sciences (TUBA); Hacettepe University Scientific Research Project Unit [013 D04 602 004]The author Z. K. thanks to Turkish Academy of Sciences (TUBA) for the partial support of this study. T. H. is grateful to Hacettepe University Scientific Research Project Unit (Grant No. 013 D04 602 004)
Genleştirilmiş perlit takviyeli farklı matrislerle metal köpük üretimi ve karakterizasyonu / Metal foam production and characterization of different matrices reinforced with expanded perlite
No full textMicrofluidic diagnostics from continuous liquid interface production additive manufacturing
No full textBiomedical diagnostics based on microfluidic devices have the potential to significantly benefit human health, however the manufacturing of microfluidic devices is a key limitation to their widespread adoption. Additive manufacturing (AM) is an attractive alternative to conventional approaches for microfluidic device manufacturing based on injection molding, however, there is a need for development of new manufacturing process capabilities and materials that are compatible for microfluidic diagnostics. In this thesis, we investigate process characteristics and capabilities of continuous liquid interface production (CLIP) based AM, focusing on aspects relevant for microfluidic device manufacturing, and validation of the materials as used in a applications of bacterial detection. We find that CLIP accurately produces microfluidic channels as small as 400 m, and that it is possible to routinely produce fluid channels as small as 100 m with high repeatability but with somewhat lower accuracy. Print orientation significantly affects the accuracy and repeatability of the process, and the best accuracy is achieved when the microchannels are parallel to the direction of motion of the build tray. We demonstrate manufacturing, assembly and packaging, and application of a microfluidic device made using CLIP for detection of E. coli bacteria using a process based on loop-mediated isothermal amplification at 65 °C. The methodology introduced in this this could be used to investigate and validate other AM process for microfluidic diagnostics, and the research highlights key issues and capabilities for CLIP and other resin-based AM processes.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2022-08-01The student, Mehmet Aydin, accepted the attached license on 2020-07-20 at 11:16.The student, Mehmet Aydin, submitted this Thesis for approval on 2020-07-20 at 11:38.This Thesis was approved for publication on 2020-07-23 at 09:03.DSpace SAF Submission Ingestion Package generated from Vireo submission #15694 on 2020-10-02 at 15:51:48Made available in DSpace on 2020-10-07T22:50:06Z (GMT). No. of bitstreams: 3
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Life satisfaction of counsellor supervisees: the role of counselling self-efficacy, trait anxiety and trait hope
No full textThe aim of the present study is to investigate the role of counselling self-efficacy, trait anxiety and trait hope in life satisfaction of novice counsellor supervisees. The sample group consisted of 360 female, 199 male and 11 undergraduate counsellors who were unwilling to report gender. Data collection tools included the Personal Information Form, the CASES, the STAI-T, The Hope Scale and the SWLS. A hypothetical structural model was developed and tested for the fit to the data. According to research findings, counselling self-efficacy was found to have a significant indirect effect on life satisfaction through trait anxiety and trait hope. Trait anxiety and trait hope were concluded to have direct effects on life satisfaction of novice counsellor supervisees.Karadeniz Technical University [SYL-2016-5475]This study was supported by Karadeniz Technical University with the code of SYL-2016-5475 and granted 1977,09 Turkish Liras. We couldn't see this information anywhere in the article. This study is produced from master's thesis of the corresponding author, Fatih Aydin. Is it possible to note it somewhere? Full details of the thesis are: Aydin, F. (2016). Effect of counseling self-efficacy, hope and anxiety on life satisfaction among counselor candidates (Unpublished master's thesis). Karadeniz Technical University, Trabzon
Adrenal lezyonlarda difüzyon ağırlıklı MRG bulguları / Diffusion weighted MRI findings in adrenal lesions?
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