989 research outputs found
Geophysical methods for monitoring soil stabilization by microbial induced carbonate precipitation
No full textUrbanization growth rate is increasing exponentially and with that comes challenging issues in urban development and environment sustainability. Generally, any development processes disturb the environment, and soil stabilization as one of the first steps in infrastructure building is no exception. However, in the past few decades, methods have been sought to reduce the possible harmful impact of soil stabilization processes on the environment. One promising method is microbial induced carbonate precipitation (MICP); in which, ubiquitous soil microorganisms stabilize the loose soil in natural and minimally harmful ways. Although MICP is continuously being studied in multi-disciplinary research, there are still ambiguities in understanding its subsurface processes. This is commonly due to lack of proper monitoring tools capable of providing coherent micro and macro scale information about MICP in subsurface. Geophysical methods are handy tools capable of providing images of the subsurface with high spatiotemporal resolution; while, being cost efficient, non-disruptive and viable for long-term monitoring applications.This thesis is investigating the efficiency of induced polarization (IP) in monitoring MICP processes and comparing it to direct monitoring methods as well as other geophysical methods. IP is known as a sensitive method to interfacial changes within fluid-grain boundaries in porous media; hence, it is a great measure to study MICP where most changes happen in this boundary (e.g., precipitation of calcite). In this three-phase study, firstly, it is shown that spectral IP (SIP) is capable of tracking changes due to calcite precipitation (the main byproduct of MICP) in the porous media, induced by chemical reactions in a laboratory scale experiment. Compared to resistivity and shear-wave velocity, SIP provided additional information with calcite precipitation pattern. Secondly, in a field scale study, time-domain IP is compared to direct monitoring approaches (e.g., chemical analysis) and showed spatial and temporal extents of MICP in the subsurface; while, direct methods failed to provide such information. And finally, in a more in depth study, it is shown that SIP can reveal frequency dependency of MICP in both laboratory and field scale settings. The additional information provided by IP compared to other methods indicate that IP is the prime candidate for monitoring MICP processes.Ph.D.Includes bibliographical reference
Konsep Kebenaran Ibnu Sina
No full textTruth is an absolute that must be achieved by human beings. It is because there is an element of the human instincts characteristic in the truth; to seek, to understand and to comprehend. Without the truth, human life would lose a barometer of humanity values. There is a problem when a standard of truth is seized by some ideologies which come from human thought. Therefore, this paper tries to research the concept of truth deeper, including the process of its presence and its causes. To shorten the long discussion of the theory of truth, the author of this article tries to focus his research on Ibnu Sina’s theory of the truth. As a great philosopher of Islam, Ibnu Sina has an ideal concept ofepistemology, so it is worthy to be studied. For the theory of truth, Ibnu Sina has an interesting view on it. According to him, the truth is contained in philosophical thinking which he describes as wisdom. He divides it into two main concepts. In addition, he also explains the the relation between the truth and the philosophy built upon three important reasons. This paper also explains the relation between the truth and the concept of mind, which is called kama>l al-awwal in Ibnu Sina’s terms. Further, this study also discusses the relation of intuition with the theory of truth. Ibnu Sina called intuition with some terms, such as ma’rifah, tah}s}i>l, and mula>h}az}a
Pursuit of excellence by Muslim scientists with a special reference to Ibn Sina / Mohd Hishamuddin A Hamid
No full textThis dissertation has the objective of studying the pursuit of excellence by Muslim Scientists during the height of Islamic Civilization with a special reference to Ibn Sina. It is hope that through this study we can obtain some information or guidelines which can be used and emulated by present day scientists to achieve the excellence that the Muslims Scientists of that time had attained. Why do we need to achieve that level of excellence? The present day predicament of the Muslim Ummah where we are ostracized, discriminated and looked down upon by friends and foes alike. We have to redeem ourselves in the eyes of the world and especially in the eyes of Allah AlMighty that we are the best Ummah and Islam is the highest way of life and be worthy of the blessing of Islam. The excellence of the Muslim scholars and scientists of yesteryears has to be recapitulated. Why Ibn sina? Ibn Sina is the most famous Muslim scholar of the Islamic civilization and some even cited him as the most excellent with his wide ranging work from medicine, astronomy, philosophy, language, politics and many other various fields. His work and life had been documented and studied since his time until the present time.
In this study the author presented the criteria for excellence and put forward the hypothesis of Iman as the special criteria that made the difference between the Muslims and the non-Muslims. The excellence and contributions of Muslim scientists during the height of Islamic civilization between the 7th-14th
Ibn Sina’s life from the influence of his parents, his earliest education and his surroundings seems to have molded his character into a dedicated and resilient scholar. He was exposed to knowledge and intellectual discussion various fields at an early age and became a competent practitioner of medicine by the age of 18. Ibn Sina had many special characteristics which can be emulated by later scholars. His dedication, his confidence, his resilience despite the hostile and rough conditions he had to endure, his power of concentration being able to work continuously for hours sometimes under difficult circumstances. Ibn Sina’s work on medicine and philosophy were and until today the most respected and most studied. His Canon of Medicine were used as the primary text for the study of medicine with some institutions in Europe using it even until the 19th century. Ibn Sina from the facts presented was a person with Iman and his early education in religious studies and able to memorize the whole of the Al Quran had made him the renowned scholar that he is although with many eccentricities. centuries were incomparable and undisputed as compared civilizations. This period produced many distinguished Muslim scholars in many varying fields of studies and their work were the basis of the development of western science. Some scholars attributed the advent of western science from the findings and works of Muslim scientists without which western science will not have achieved or attained the present dominance and prominence.
The Ummah to recap the excellence of yesteryears, they have to study their history, the sirah of the Prophet Mohamad SAW, the earlier Quranic generation of the sahabahs, the tabiin and the scholars. Many of their efforts and practices that made them knowledgeable and respected had not been sustained thus resulting in the mundane and oppressed Ummah of the period after the 14th century until
present. The factors which brought Islamic Civilization to the height of its glory were scrutinized and also that which brought the decline in order to find the remedies.
In conclusion the Ummah was blessed with excellence and glory when they have Iman and practiced Islam as a way of life. The lessons from the period of glory of the Islamic Civilization have to be learnt and emulated and pray and be confident that Islam will bring again the glory in this world and the hereafter
Pemikiran Filosofis Pendidikan Ibnu Sina Dan Implikasinya Pada Pendidikan Islam Kontemporer
No full textAbstract The central issue faced by the Muslim world, especially Islamic education today is the inception of secular science. Science is presented in the form of dichotomy. To pave the issue of Islamic education, the required reconstruction of the educational philosophy of Islam. In order to answer this question the author tries to present the ideas of Ibn Sina were rational religious scented. Ibn Sina is a figure of Islamic education which produces a lot of work in various fields of science, especially medicine and education, Ibn Sina emphasizes education was held by non-dichotomous. Educational purposes thinks should be directed towards preparing a person to be able to live in the community together with the conduct of expertise chosen according to their talents and potentials. Therefore, the curriculum is conceived by Ibn Sina conceived and developed based on the stage of growth and development of the Child. Keywords: Thinking Education, Ibnu Sina, and Implication
Hyaluronic Acid in Nanopharmaceuticals: An Overview
No full textHyaluronic acid (HA) is a naturally occurring, long, unbranched polysaccharide that plays a critical role in maintaining skin structure and hydration. Its unique properties make it a valuable component in the field of nanopharmaceuticals. The combination of HA into nanopharmaceuticals enhances its ability to interact with various therapeutic agents, improving the delivery and efficacy of drugs. HA-based nanoparticles, including solid lipid nanoparticles, and polymeric nanogels, offer controlled release, enhanced stability, and targeted delivery of therapeutic agents. These innovations significantly improve therapeutic outcomes and reduce side effects, making HA an essential tool in modern medicine. In general, HA-modified liposomes enhance drug encapsulation and targeting, while HA-modified solid lipid nanoparticles (SLNs) provide a solid lipid core for drug encapsulation, offering controlled release and stability. This article provides an overview of the potential applications and recent advancements of HA in nanopharmaceuticals, emphasizing its significant impact on the evolving field of targeted drug delivery and advanced therapeutic strategies. By delving into the unique properties of HA and its compatibility with various therapeutic agents, this review underscores the promising potential of HA in revolutionizing nanopharmaceuticals
Fungsi Naskah Prudak Sina Dalam Kehidupan Masyarakat Sasak Dalam Perspektif Nilai Agama Dan Pendidikan
No full text: Prudak Sina is a character in wise and prudent story, either in thought, word and in deeds . He is Lelananging Jagad that should be loved by the men on earth and as a shelter for women. It contains very deep meaning in terms of the philosophy of the teachings of Islam. Prudak Sina's script in dialogue with his wife contains a number of values and functions which is a typical pattern of Sasak people in the past, noble values that should be the basis and model for every man in thinking, saying and acting to his wife. This qualitative study involved some good resource such as connoisseur, poet, staff supporter, and script reader who are credible enough to understand and sing papyrus manuscript. The data obtained then ana-lyzed using descriptive analysis in the form of extraction. The results of this study are religiosity and education. Ki Prudak Sina, the author as well as the character of this story, preached Islam through songs such Prudak Sina song. Based on these conclusions, the author suggests to take wisdom and examples of exem-plary character highlighted by the author especially in intercourse with wife as a companion of life
HPLC METHOD DEVELOPMENT AND VALIDATION FOR METFORMIN AND PHENYL BUTYRIC ACID AND IN VITRO EVALUATION OF THEIR PEGYLATED LIPOSOMAL FORMULATION AGAINST COLORECTAL CANCER
No full textObjective: This study aimed to develop a PEGylated liposomal formulation combining Metformin (MET) and Phenyl Butyric Acid (PBA) for colorectal cancer treatment. Current colorectal cancer therapies face limitations such as poor drug solubility, rapid clearance, and systemic toxicity. Combining MET and PBA in liposomes could potentially overcome these limitations by enhancing drug stability, prolonging circulation time, and improving targeted delivery.
Methods: A High-Performance Liquid Chromatography (HPLC) method was optimized and validated for the simultaneous quantification of MET and PBA, achieving calibration curve R² values above 0.99. Liposomal formulations were prepared, and encapsulation efficiencies were evaluated. Sustained drug release was studied over 72 h at 37 °C. Cytotoxicity assays were conducted using colorectal cancer cell lines HCT116 and HT29. Additionally, colony formation assays assessed the formulation\u27s long-term effects on cell proliferation.
Results: The liposomal formulation showed encapsulation efficiencies of 48% for Lip-MET and 56.8% and 83.9% for Lip-MET-PBA. Sustained release profiles were observed, with 60% of MET and 55% of PBA released over 72 h. Cytotoxicity assays revealed that Lip-MET-PBA significantly reduced cell viability in HCT116 and HT29 cell lines, with IC50 values of 0.65 mmol and 0.82 mmol, respectively, compared to MET alone (1.1 mmol and 1.3 mmol). Colony formation assays demonstrated a concentration-dependent reduction in colony numbers, highlighting the enhanced anticancer efficacy of the combination. Statistical analysis showed significant differences (p<0.05) in cell viability and colony formation between the liposomal formulation and the free drugs.
Conclusion: This is the first PEGylated liposomal formulation combining MET and PBA, offering a promising strategy for colorectal cancer therapy. The formulation combines sustained release, improved cytotoxicity, and a significant impact on colony formation, warranting further in vivo investigations
THEORETICAL AND IDEOLOGICAL SOURCES OF IBN SINA PHILOSOPHY ON THE ISSUE OF REASON AND FAITH
No full textThe article examines the theoretical and ideological sources of Ibn Sina philosophy on the issue of human. The author emphasizes that the studies of Ibn Sina were based on the philosophical tradition of antiquity, on their doctrine of man as a rational and social person. Due to the rational activity of man as his natural qualities, the philosopher based on the modern advanced science and social thought which has significantly expanded the frontiers of knowledge on the issues of human nature, the meaning of his life, his place in the Universe, and role in society.</p
Using Contents to Improve Social Media Engagement on Sina Weibo: Case HAMK
No full textThis thesis is commissioned by HAMK. HAMK is the abbreviation and brand name for Häme University of Applied Sciences. It is a multidisciplinary higher education institution located in Hämeenlinna, Finland. As part of its international marketing project for the Chinese market, HAMK started its presence on the Chinese social media outlet Sina Weibo in October 2014. The purpose of this thesis was to find out for foreign universities on Sina Weibo, how content types and characteristics influenced social media engagement, especially the engagement of sharing. Therefore, HAMK can utilize this study result to improve its social media engagement performance on Sina Weibo in the future.
Besides researching and reviewing the relevant literature, the author also conducted a case study as empirical research. Based on the method of content analysis, the case study analysed a total of 412 contents on Sina Weibo published from five foreign universities including HAMK.
The findings showed different content types and different content
characteristics had a different influence on social media engagement, also on the engagement of sharing for foreign universities for Sina Weibo, and certain types and characteristics had a higher positive or negative influence.
This study contributes to the existing knowledge of using contents to improve social media engagement. It especially provides insight for the commissioning university HAMK for its possible plan to improve the social media engagement on Sina Weibo in the future
EFEKTIVITAS PENGGUNAAN MEDIA AUDIO VISUAL DALAM MENINGKATKAN HASIL BELAJAR PESERTA DIDIK DI SMP IT IBNU SINA MERAUKE
No full textThis study focuses on discussing the effectiveness of using audio-visual learning media in improving student learning outcomes in PAI subjects at SMP IT Ibnu Sina Merauke. In accordance with the title that the author took, the type of research conducted by the author was field qualitative (Field Research). This type of qualitative field research (Field Research) is research that requires researchers to go to the field to make observations about a phenomenon in a natural state. By way of observation, interviews and documentation related to the problem to be studied. Field qualitative research conducted by the author aims to examine and determine the effectiveness of using audio-visual learning media in improving student learning outcomes in PAI subjects at SMP IT Ibnu Sina Merauke. After analyzing the conditions in the field, the results show that the learning process is carried out using audio-visual learning media at SMP IT Ibnu Sina Merauke, it is necessary to carry out several stages, namely: the preparation stage, the planning stage, the implementation stage and the evaluation stage. Then the factors that cause an increase in student learning outcomes by using audio-visual learning media, including: Facilities and infrastructure, teachers, students and the environment. Forms of using audio-visual learning media in improving student learning outcomes at SMP IT Ibnu Sina Merauke, use three forms, namely: forms of motivation, forms of information and forms of teaching. It can be said that the use of audio-visual learning media is very effective in improving student learning outcomes, especially in PAI subjects at SMP IT Ibnu Sina Merauke. As an implication of this research it is recommended that schools should provide facilities and infrastructure to support the learning process, especially audio-visual learning media. With this media, every learning, especially in PAI subjects, will be fun learning and produce the maximum expected achievement of learning objective
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