535 research outputs found
MERAD (Ali), L’Exégèse coranique
Get PDFA.M. tente ici de fournir aux lecteurs un guide pour une lecture « éclairée » et éclairante du livre sacré des musulmans : le Coran. Devant la montée des lectures restrictives du livre saint, l’auteur – qui se situe dans la lignée du courant rationaliste algérien (M. Bennabi, M. Arkoun et T. Ibrahimi) – tente de montrer le champ diversifié des lectures possibles de la parole divine. Au travers de cette diversité, une interprétation libérale et rationaliste se précise pour fonder une compréhen..
Uncertainty analysis of well test data
No full textDue to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to [email protected], referencing the URI of the item.Includes bibliographical references (leaf 90).Issued also on microfiche from Lange Micrographics.During a well test a transient pressure response is created by a temporary change in production rate. The well response is usually monitored during a relatively short period of time, depending upon the test objectives. Reservoir properties are determined from well test data via an inverse problem approach. Uncertainty is inherent in any nonlinear inverse problem. Unfortunately, well test interpretation suffers particularly from a variety of uncertainties that, when combined, reduce the confidence that can be associated with the estimated reservoir properties. The specific factors that have been analyzed in this work are: 1. Pressure noise (random noise) 2. Pressure drift (systematic variation) 3. Rate history effects Our work is based on the analysis of the effects of random pressure noise, the drift error, and the rate history on the estimation of typical reservoir parameters for two common reservoir models: A vertical well with a constant wellbore storage and skin in a homogeneous reservoir. A vertical well with a finite conductivity vertical fracture including wellbore effects in a homogeneous reservoir. This work represents a sensitivity study of the impact of pressure and rate uncertainty on parameter estimation and the confidence intervals associated with these results. In this work we statistically analyze the calculated reservoir parameters to quantify the impact of pressure and rate uncertainty on them
MERAD (Ali), L’Exégèse coranique
Get PDFA.M. tente ici de fournir aux lecteurs un guide pour une lecture « éclairée » et éclairante du livre sacré des musulmans : le Coran. Devant la montée des lectures restrictives du livre saint, l’auteur – qui se situe dans la lignée du courant rationaliste algérien (M. Bennabi, M. Arkoun et T. Ibrahimi) – tente de montrer le champ diversifié des lectures possibles de la parole divine. Au travers de cette diversité, une interprétation libérale et rationaliste se précise pour fonder une compréhen..
Assessment of an Automatic Prosthetic Elbow Control Strategy Using Residual Limb Motion for Transhumeral Amputated Individuals With Socket or Osseointegrated Prostheses
Get PDFTerminal differentiation of dendritic cells
No full textDendritic cells (DCs) are essential for the initiation of an effective immune response. Despite this, our understanding of the molecular regulation of this important cell type has lagged significantly behind that of other lymphoid populations such as B and T cells, but recent development of various tools has greatly facilitated progress in the field. Here, we review the transcription factors that drive peripheral DC subset fate decisions. While Pu.1, Ikaros, and Gfi-1 are essential for precursor DCs to give rise to monocytes, conventional DCs, and plasmacytoid DCs, the balance between E2-2 and Id2 directs committed precursors along a pDC or cDC lineage, respectively. Several transcription factors such as Batf3, Nfil3, and Id2 are required for different DC subsets at steady-state and drive segregation into the individual DCs subsets late in development in the CD8 lineage. During inflammation, CD8-expressing DCs emerge that feature many of the hallmarks of classical CD8α DCs but surprisingly do not depend on the same transcription factors. Thus, the immune system has developed two pathways of DC differentiation that enable it to maintain homeostatic balance and to respond rapidly to the emergency requirement for DCs that might occur during infection
Expression of the Chemokine Binding Protein M3 Promotes Marked Changes in the Accumulation of Specific Leukocytes Subsets Within the Intestine
No full textBackground & Aims: Chemokines are small proteins that direct leukocyte trafficking under homeostatic and inflammatory conditions. We analyzed the differential expression of chemokines in distinct segments of the intestine and investigated the importance of chemokines for the distribution of leukocytes in the intestine during homeostatic and inflammatory conditions. Methods: We analyzed messenger RNA for all known chemokines in different segments of the gut by quantitative polymerase chain reaction. To study the effect of multiple-chemokine blockade in the gut, we generated transgenic mice that expressed the chemokine binding protein M3 in the intestine (V-M3 mice). We used flow cytometry to evaluate the changes in the numbers of leukocytes. Results: We observed distinct chemokine expression profiles in the 6 segments of the gut. Some chemokines were expressed throughout the intestine (CCL28, CCL6, CXCL16, and CX3CL1), whereas others were expressed preferentially in the small (CCL25 and CCL5) or large intestine (CCL19, CCL21, and CXCL5). Expression of the chemokine blocker M3 in intestinal epithelial cells resulted in reduced numbers of B and T cells in Peyer's patches, reduced numbers of intraepithelial CD8αβ+/TCRαβ+ and CD8αα+/TCRαβ+ T cells, and reduced numbers of lamina propria CD8+ T cells. Strikingly, M3 expression markedly reduced the number of eosinophils and macrophages in the small and large intestines. Dextran sulfate sodium treatment of control mice led to marked changes in the expression of chemokines and in the number of myeloid cells in the colon. These cellular changes were significantly attenuated in the presence of M3. Conclusions: Our study reveals a complex pattern of chemokine expression in the intestine and indicates that chemokines are critical for leukocyte accumulation in the intestine during homeostasis and inflammation
Skeletal muscle density predicts prognosis in patients with metastatic renal cell carcinoma treated with targeted therapies
No full textBACKGROUND Studies have shown that skeletal muscle and adipose tissue are linked to overall survival (OS) and progression-free survival (PFS). Because targeted therapies have improved the outcome in patients with metastatic renal cell carcinoma (mRCC), new prognostic parameters are required. The objective of the current study was to analyze whether body composition parameters play a prognostic role in patients with mRCC. METHODS Adipose tissue, skeletal muscle, and skeletal muscle density (SMD) were assessed with computed tomography imaging by measuring cross-sectional areas of the tissues and mean muscle Hounsfield units (HU). A high level of mean HU indicates a high SMD and high quality of muscle. OS and PFS were estimated using the Kaplan-Meier method and compared with the log-rank test. The multivariable Cox proportional hazards model was adjusted for Heng risk score and treatment. RESULTS In the 149 patients studied, the median OS was 21.4 months and was strongly associated with SMD; the median OS in patients with low SMD was approximately one-half that of patients with high SMD (14 months vs 29 months; P=.001). After adjustment for Heng risk score and treatment, high SMD was associated with longer OS (hazards ratio, 1.85; P=.004) and longer PFS (hazards ratio, 1.81; P=.002). Adding SMD will separate the intermediate-risk and favorable-risk groups into 3 groups, with different median OS periods ranging from 8 months (95% confidence interval [95% CI], 6 months-12 months) for an intermediate-risk Heng score/low SMD to 22 months (95% CI, 14 months-27 months) for an intermediate-risk Heng score/high SMD and a favorable-risk Heng score/low SMD to 35 months (95% CI, 24 months-43 months) for a favorable-risk Heng score/high SMD. CONCLUSIONS High muscle density appears to be independently associated with improved outcome and could be integrated into the prognostic scores thereby enhancing the management of patients with mRCC. Cancer 2013;119:3377-84. (c) 2013 American Cancer Society
In-depth tissue profiling using multiplexed immunohistochemical consecutive staining on single slide
No full textItem does not contain fulltex
Electrical And Magnetic Properties Of New Compounds Of The Conductor Anion [ni(dmit)2]- And Nitronyl Nitroxide Magnetic Radicals [propriedades Elétricas E Magnéticas De Novos Compostos Com O ânion Condutor [ni(dmit)2]- E Radicais Magnéticos Nitronil Nitróxido]
No full textThree compounds have been synthesized with formulae [3-MeRad][Ni(dmit) 2] (1), [4-MeRad][Ni(dmit)2] (2) and [4-PrRad][Ni(dmit) 2] (3) where [Ni(dmit)2]- is an anionic π-radical (dmit = 1,3-dithiol-2-thione-4,5-dithiolate) and [3-MeRad] + is 3-N-methylpyridinium α-nitronyl nitroxide, [4-MeRad] + is 4-N-methylpyridinium α-nitronyl nitroxide and [4-PrRad]+ is 4-N-propylpyridinium α-nitronyl nitroxide. The temperature-dependent magnetic susceptibility of 1 revealed that an antiferromagnetic interaction operates between the 3-MeRad+ radical cations with exchange coupling constants of J1 = - 1.72 cm -1 and antiferromagnetism assigned to the spin ladder chains of the Ni(dmit)2 radical anions. Compound 1 exhibits semiconducting behavior and 3 presents capacitor behavior in the temperature range studied (4 - 300 K).304904908Steimecke, G., Sieler, H.J., Kirmse, R., Hoyer, E., (1979) Phosphorus, Sulfur Silicon Relat. Elem, 7, p. 49Pullen, A.E., Olk, R.M., (1999) Coord. Chem. Rev, 188, p. 211Valade, L., Legros, J.P., Bousseau, M., Cassoux, P., (1985) J. Chem. Soc. Dalton Trans, p. 783Valade, L., Caro, D., Basso-Bert, M., Malfant, I., Faulman, C., Bonneval, B.G., Legros, J.P., (1986) Coord. Chem. Rev, 2005, p. 249Bates, J.R., Kathirgamanathan, P., Miles, R.W., (1997) Thin Solid Films, 299, p. 18Pearson, C., Moore, A.J., Gibson, J.E., Bryce, M.R., Petty, M.C., (1994) Thin Solid Films, 244, p. 932Wang, S.F., Huang, W.T., Zhang, T.Q., Yang, H., Gong, Q.H., Okuma, Y., Horikiri, M., Miura, Y.F., (1999) Appl. Phys. Lett, 75, p. 1845Bousseau, M., Valade, L., Legros, J.P., Cassoux, P., Garbauskas, M., Iterrante, L.V., (1986) J. Am. Chem. Soc, 108, p. 1908Nakamura, T., Underhill, A.E., Coomber, A.T., Friend, R.H., Tajima, H., Kobayashi, A., Kobayashi, H., (1995) Inorg. Chem, 34, p. 870Charlton, A., Underhill, A.E., Kobayashi, A., Kobayashi, H., (1995) J. Chem. Soc. Dalton Trans, p. 1285Bai, F., Zuo, J.L., Shen, Z., You, X.Z., Fun, H.K., Chinnakali, K., (2000) Inorg. Chem, 39, p. 1322Miura, Y.F., Kawasaki, T., Ohnishi, H., Okuma, Y., Sugi, M., (1999) Mol. Cryst. Liq. Cryst. Sci. Technol., A, 337, p. 365Wang, X.Q., Yu, W.T., Xu, D., Wang, Y.L., Li, T.B., Zhang, G.H., Sun, X.B., Ren, Q., (2005) Acta Crystallogr., Sect. E: Struct. Rep. Online, 61, pp. M717Akutagawa, T., Matsuura, K., Hashimoto, A., Nakamura, T., (2005) Inorg. Chem, 44, p. 4454Takahashi, K., Cui, H.B., Kobayashi, H., Einaga, Y., Sato, O., (2005) Chem. Lett, 34, p. 1240Fourmigué, M., Narcis, A., (2005) J. Chem. Soc. Dalton Trans, 8, p. 1365Ishii, Y., Tamura, M., Kato, R., Hedo, M., Uwatoko, Y., Mori, N., (2005) Synth. Met, 152, p. 389Aonuma, S., Casellas, H., Faulmann, C., Bonneval, B.G., Malfant, I., Lacroix, P.G., Cassoux, P., Inoue, K., (2001) Synth. Met, 120, p. 993Imai, H., Inabe, T., Otsuka, T., Okuno, T., Awaga, K., (1996) Phys. Rev. B: Condens. Matter Mater. Phys, 54, pp. R6838Faulmann, C., Pullen, A.E., Rivière, E., Jpurnaux, Y., Cassoux, P., (1999) Synth. Met, 103, p. 2296Imai, H., Naito, T., Awaga, K., Inabe, T., (2001) Synth. Met, 120, p. 951Stumpf, H.O., Ouahab, L., Pey, Y., Grejean, D., Khan, O., (1993) Science, 261, p. 447Ullman, E.F., Call, L., Osieki, J.H., (1970) J. Org. Chem, 35, p. 3630Vaz, M.G.F., Pedroso, E.F., Speziali, N.L., Novak, M.A., Alcântara, A.F.C., Stumpf, H.O., (2001) Inorg. Chim. Acta, 326, p. 65Vaz, M.G.F., Pinheiro, L.M.M., Stumpf, H.O., Alcântara, A.F.C., Golhen, S., Ouahab, L., Cador, O., Kahn, O., (1999) Chem. Eur. J, 5, p. 1486Vaz, M.G.F., (1998) Tese de Doutorado, , Universidade Federal de Minas Gerais, BrasilKirmse, R., Stach, J., Dietzsch, W., Steimecke, G., Hoyer, E., (1980) Inorg. Chem, 19, p. 2679Valdes, L.B., (1954) Proceedings of the Institute of Radio Engineers, 42, p. 420Khan, O., (1993) Molecular Magnetism, pp. 1-4. , VCH: New YorkKopf, P.W., Kreilick, R., Boocock, D.G.B., Ullman, E.F., (1970) J. Am. Chem. Soc, 92, p. 4531Pokhodnya, K.J., Faulmann, C., Malfant, I., Solano, R.A., Cassoux, P., Mlayah, A., Smirnov, D., Leotin, J., (1999) Synth. Met, 103, p. 2016Xiao, C., Feng, K., Mo, Y., Meng, Q., Zhang, M., Wan, M., Zhao, J., (1998) Chem. Phys, 237, p. 73Troyer, M., Tsunetsugu, H., Würtz, D., (1994) Phys. Rev. B: Condens. Matter Mater. Phys, 50, p. 13515Ashcroft, N.W., Mermin, N.D., (1976) Solid State Physics, pp. 562-564. , Saunder Coll Publishing: New YorkMalvino, A.P., (1997) Eletrônica, , Makron Books: São PauloJäckel, F., Watson, M.D., Müllen, K., Rabe, J.P., (2004) Phys. Rev. Lett, 92, p. 18830
TOWARDS GUIDED UNDERWATER SURVEY USING LIGHT VISUAL ODOMETRY
Get PDFA light distributed visual odometry method adapted to embedded hardware platform is proposed. The aim is to guide underwater
surveys in real time. We rely on image stream captured using portable stereo rig attached to the embedded system. Taken images are
analyzed on the fly to assess image quality in terms of sharpness and lightness, so that immediate actions can be taken accordingly.
Images are then transferred over the network to another processing unit to compute the odometry. Relying on a standard ego-motion
estimation approach, we speed up points matching between image quadruplets using a low level points matching scheme relying on fast
Harris operator and template matching that is invariant to illumination changes. We benefit from having the light source attached to the
hardware platform to estimate a priori rough depth belief following light divergence over distance low. The rough depth is used to limit
points correspondence search zone as it linearly depends on disparity. A stochastic relative bundle adjustment is applied to minimize
re-projection errors. The evaluation of the proposed method demonstrates the gain in terms of computation time w.r.t. other approaches
that use more sophisticated feature descriptors. The built system opens promising areas for further development and integration of
embedded computer vision techniques
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