2,184 research outputs found
Dopamine D2/D3 receptor availability in genetically leptin-deficient patients after long-term leptin replacement
No full textAbstract not availableK Ishibashi, S M Berman, G Paz-Filho, B Lee, C Robertson, M A Mandelkern, M-L Wong, J Licinio, E D Londo
Better Regulation in the European Union
No full textThis is the author accepted manuscript. The final version is available from Edward ElgarIn this chapter, we outline the foundations of better regulation by reviewing the historical record tracing the main episodes. Specifically, we cover: the 1992 Edinburgh summit to the Mandelkern Report of 2001, the Prodi Commission’s package on regulatory reform, impact assessment and consultation, the dialogue between the Council and the Commission on setting targets for administrative burdens, the rise of regulatory oversight first with the Impact Assessment Board (2007) and then with the Regulatory Scrutiny Board (RSB), the Juncker-Timmermans vision for better regulation and the commitment to regulatory off-setting of the von der Leyden Commission. With the foundations laid, we finally explore what lies ahead
What ‘must’ adds
No full textThere is a difference between the conditions in which one can felicitously use a ‘must’-claim like and those in which one can use the corresponding claim without the ‘must’, as in 'It must be raining out' versus 'It is raining out. It is difficult to pin down just what this difference amounts to. And it is difficult to account for this difference, since assertions of 'Must p' and assertions of p alone seem to have the same basic goal: namely, communicating that p is true. In this paper I give a new account of the conversational role of ‘must’. I begin by arguing that a ‘must’-claim is felicitous only if there is a shared argument for the proposition it embeds. I then argue that this generalization, which I call Support, can explain the more familiar generalization that ‘must’-claims are felicitous only if the speaker’s evidence for them is in some sense indirect. Finally, I propose a pragmatic derivation of Support as a manner implicature
Practical Moore Sentences
No full textI discuss what I call practical Moore sentences: sentences like ‘You must close your door, but I don’t know whether you will’, which combine an order together with an avowal of agnosticism about whether the order will be obeyed. I show that practical Moore sentences are generally infelicitous. But this infelicity is surprising: it seems like there should be nothing wrong with giving someone an order while acknowledging that you do not know whether it will obeyed. I suggest that this infelicity points to a striking psychological fact, with potentially broad ramifications concerning the structure of norms of speech acts: namely, when giving an order, we must act as if we believe we will be obeyed
How to do things with modals
No full textMind &Language, Volume 35, Issue 1, Page 115-138, February 2020
Thermodynamics of Shrinkage of Fibrous (Racked) Rubber
No full textAbstract
Highly oriented natural rubber samples of Roberts and Mandelkern, prepared by racking and subsequently crosslinked using γ-radiation, undergo a spontaneous shrinkage upon melting which closely resembles the shrinkage of collagen. If the transformation is arrested by application of a tensile force, a state of equilibrium may be established between two distinct zones, or phases, one being totally amorphous (shrunken) and the other unchanged (i.e., racked). Determination of the stress τeq required for phase equilibrium at various temperatures is described. Extrapolation to τeq=0 gives equilibrium melting temperatures Tmi, which are about 8° below the temperatures Tsi for spontaneous shrinkage. The heat of transformation of racked to amorphous rubber calculated from the dependence of τeq on T is 4.5 cal g−1. Since the degree of crystallinity is only 0.24, the heat of fusion calculated for 1 g of crystalline rubber is ca. 19 cal, which agrees satisfactorily with the value 15.3 cal, deduced by Roberts and Mandelkern through use of the melting point depression method. The shrinkage of racked rubber displays all of the important features associated with the similar contraction of fibrous proteins.</jats:p
Measurement of the mass difference m(B-0)-m(B+)
No full textUsing 230 x 10(6) B (B) over bar events recorded with the BABAR detector at the e(+)e(-) storage rings PEP-II, we reconstruct approximately 4100 B-0 -> J/psi K+pi(-) and 9930 B+ -> J/psi K+ decays with J/psi -> mu(+)mu(-) and e(+)e(-). From the measured B-momentum distributions in the e(+)e(-) rest frame, we determine the mass difference m(B-0) - m(B+) = (+0.33 +/- 0.05 +/- 0.03) MeV/c(2)
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