586 research outputs found

    Chromophores and chemical composition of brown carbon characterized at an urban kerbside by excitation-emission spectroscopy and mass spectrometry

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    The data in the Excel files are related to the publication Jiang et al., ACP, 2022. Each sheet of the Excel files corresponds to one plot in the publication as repeated below. The data originates mainly from Aqualog and FIGAERO-CIMS measurements. The figures and captions from the publication are shown in the following to allow for a good understanding of the data files. Jiang, F., Song, J., Bauer, J., Gao, L., Vallon, M., Gebhardt, R., Leisner, T., Norra, S., and Saathoff, H.: Chromophores and chemical composition of brown carbon characterized at an urban kerbside by excitation-emission spectroscopy and mass spectrometry, Atmos. Chem. Phys. Discuss. [preprint], https://doi.org/10.5194/acp-2022-465, in review, 2022

    New European Training Network solving corrosion problems on micro- and nanoscale: mCBEEs

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    mCBEEs is an acronym for: Advanced integrative solutions to Corrosion problems beyond micro-scale: towards long-term durability of miniaturised Biomedical, Electronic and Energy systems. It is a doctoral student training network funded by the European Commission under the Marie Sklodowska-Curie Action scheme in the same way as the recently reported training network SELECTA that is focusing on smart electrodeposited alloys for environmentally sustainable applications

    Chromophores and chemical composition of brown carbon characterized at an urban kerbside by excitation-emission spectroscopy and mass spectrometry

    No full text
    The data in the Excel files are related to the publication Jiang et al., ACP, 2022. Each sheet of the Excel files corresponds to one plot in the publication as repeated below. The data originates mainly from Aqualog and FIGAERO-CIMS measurements. The figures and captions from the publication are shown in the following to allow for a good understanding of the data files. Jiang, F., Song, J., Bauer, J., Gao, L., Vallon, M., Gebhardt, R., Leisner, T., Norra, S., and Saathoff, H.: Chromophores and chemical composition of brown carbon characterized at an urban kerbside by excitation-emission spectroscopy and mass spectrometry, Atmos. Chem. Phys. Discuss. [preprint], https://doi.org/10.5194/acp-2022-465, in review, 2022

    Comparison of scanning aerosol LIDAR and in situ measurements of aerosol physical properties and boundary layer heights

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    The spatiotemporal distribution of aerosol particles in the atmosphere has a great impact on radiative transfer, clouds, and air quality. Modern remote sensing methods, as well as airborne in situ measure- ments by unpiloted aerial vehicles (UAV) or balloons, are suitable tools to improve our understanding of the role of aerosol particles in the atmosphere. To validate the measurement capabilities of three relatively new measurement systems and to bridge the gaps that are often encountered between remote sensing and in situ ob- servation, as well as to investigate aerosol particles in and above the boundary layer, we conducted two measure- ment campaigns and collected a comprehensive dataset employing a scanning aerosol lidar, a balloon-borne ra- diosonde with the Compact Optical Backscatter Aerosol Detector (COBALD), an optical particle counter (OPC) on a UAV, and a comprehensive set of ground-based instruments. The extinction coefficients calculated from near-ground-level aerosol size distributions measured in situ are well correlated with those retrieved from lidar measurements, with a slope of 1.037 ± 0.015 and a Pearson correlation coefficient of 0.878, respectively. Verti- cal profiles measured by an OPC-N3 on a UAV show similar vertical particle distributions and boundary layer heights to lidar measurements. However, the sensor, OPC-N3, shows a larger variability in the aerosol backscat- ter coefficient measurements, with a Pearson correlation coefficient of only 0.241. In contrast, the COBALD data from a balloon flight are well correlated with lidar-derived backscatter data from the near-ground level up to the stratosphere, with a slope of 1.063 ± 0.016 and a Pearson correlation coefficient of 0.925, respectively. This consistency between lidar and COBALD data reflects the good data quality of both methods and proves that lidar can provide reliable and spatial distributions of aerosol particles with high spatial and temporal resolutions. This study shows that the scanning lidar has the capability to retrieve backscatter coefficients near the ground level (from 25 to 50 m above ground level) when it conducts horizontal measurement, which is not possible for verti- cally pointing lidar. These near-ground-level retrievals compare well with ground-level in situ measurements. In addition, in situ measurements on the balloon and UAV validated the scanning lidar retrievals within and above the boundary layer. The scanning aerosol lidar allows us to measure aerosol particle distributions and profiles from the ground level to the stratosphere with an accuracy equal to or better than in situ measurements and with a similar spatial resolution

    CIB1: a small protein with big ambitions

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    Calcium- and integrin-binding protein 1 (CIB1) is a small, ubiquitously expressed protein that was first identified as an intracellular binding partner of a platelet-specific α-integrin cytoplasmic tail. Although early studies revealed a role for CIB1 in regulating platelet integrin activity, recent studies have indicated a more diverse role for CIB1 in many different cell types and processes, including calcium signaling, migration, adhesion, proliferation, and survival. Increasing evidence also points to a novel role for CIB1 in cancer and cardiovascular disease. In addition, an array of CIB1 binding partners has been identified that provide important insight into how CIB1 may regulate these processes. Some of these binding partners include the serine/threonine kinases, p21-activated kinase 1 (PAK1), apoptosis signal-regulating kinase 1 (ASK1), and polo-like kinase 3 (PLK3). Structural and mutational studies indicate that CIB1 binds most or all of its partners via a well-defined hydrophobic cleft. Although CIB1 itself lacks known enzymatic activity, it supports the PI3K/AKT and MEK/ERK oncogenic signaling pathways, in part, by directly modulating enzymes in these pathways. In this review, we discuss our current understanding of CIB1 and key questions regarding structure and function and how this seemingly diminutive protein impacts important signaling pathways and cellular processes in human health and disease.-Leisner, T. M., Freeman, T. C., Black, J. L., Parise, L. V. CIB1: a small protein with big ambitions

    Stadt-Theater Düsseldorf / Die Zauberflöte : Freitag, den 23. Januar 1914 ; Gastspiel von Melitta Heim vom Opernhaus Frankfurt a. M. ; Oper in 2 Akten

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    von Emanuel Schikaneder. Musik von Wolfgang Amadeus Mozart. Spielleitung: Robert Leffler. Musikalische Leitung: Werner Wolff. Personen: Erich Hanfstaengl, Dr. Hans Copony vom Hoftheater Wiesbaden als Gast auf Engagement, Hubert Mertens, Peter Kirschbaum, Ernst Bedau, Gustav Waschow, Aennchen Heyter, Eugen Albert, Melitta Heim vom Opernhaus Frankfurt a. M., Agnes Wedekind-Klebe, Johanna Leisner, Else Bräuner, Magda Spiegel, Annie Ligthart, Emma Prothmann, Paula Conrad, Heinrich Niggemeier, Rudolf Walter, Josef Zanders, Wilhelm Buch, Carl Gericke ..
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