56 research outputs found
CORRELATION BETWEEN NAILFOLD VIDEOCAPILLAROSCOPY PATTERNS, LEFT VENTRICLE DYSFUNCTION AND PULMONARY DISEASE IN SYSTEMIC SCLEROSIS,
No full textBackground: Systemic Sclerosis (SSc) is a multisystem connective disease characterized by a microvascular damage, which leads to systemic fibrosis, immune dysregulation and progressive involvement of internal organs [1].
According to the classification of the morphological aspects, into the scleroderma pattern proposed by Cutolo et al. are described the early, active and late patterns.
Objectives: The aim of our study is thus to report a correlation between specific nailfold videocapillaroscopy pattern and internal organ involvement.
Methods: All enrolled patients were diagnosed for SSc, according to the American College of Rheumatology criteria and underwent an echocardiographic examination and a nailfold videocapillaroscopy.
Myocardial function parameters considered were: global contractility (computed with the Simpson method), linear contractility (computed through the MAPSE) [2], diastolic dysfunction (through the analysis of the trans-mitral flow) [3]; whilst those of lung damage were: PAPs and the evaluation of the right ventricle contractility through the TAPSE [4].
Statistics were performed with SPSS 20 software, by using the Mann Whitney U Test and the Fisher Test.
Results: We enrolled 27 patients, of which 16 showing “active pattern” and 11 “early pattern”, compared to a group of 21 healthy controls.
Of the 11 patients belonging to the “early” group, 1 resulted affected by diastolic dysfunction, whilst 3 had pulmonary hypertension, defined by PAPs ≥40 mmHg [4] (early vs controls; p=0.03). In the 16 patients of the “active” group. instead, 5 were found to have a diastolic dysfunction (active vs controls; p=0.01) and 6 pulmonary hypertension (active vs controls; p=0.003). In the group with “active” pattern we also observed a reduction in TAPSE compared to the control group (2,0 ± 0,2 vs 2,2 ± 0,2; p=0,025) and compared to the group with early pattern (2,0 ± 0,2 vs 2,2 ± 0,3; p=0,07).
No presence of modifications in the global contractility emerged; however, we observed a progressive reduction of the MAPSE (controls 1.76 ± 0,08; early 1.57 ± 0,04; active 1.49 ± 0,12), which resulted statistically significant among the different comparisons (controls vs early p=0.001; controls vs active p=0.0001; early vs active p=0.04).
Conclusion: The analyses showed a strict correlation between the severity of the microvascoular alterations, reported by nailfold videocapilloroscopy, and the severity of the cardiopulmonary damage, expressed by an increase in the percentage of pulmonary hypertension, diastolic dysfunction and a progressive reduction of MAPSE and TAPSE.
Abstract AB1155 Table 1
early vs controls
EARLY CONTROLS P
PAPs 32,3 ± 5,4 22,6 ± 6,7 0,0001
TAPSE 2,2 ± 0,3 2,2 ± 0,2 NS
MAPSE 1,57 ± 0,04 1,76 ± 0,08 0,0001
EF 65 ± 4 64 ± 2,7 NS
E/A 1,34 ± 0,2 1,38 ± 0,19 NS
DECT 148 ± 23 163 ± 27 NS
Diastolic dysfunction 1(11) 0(21) 0,3
Pulmonary hypertension 3(11) 0(21) 0,03
Abstract AB1155 Table 2
active vs controls
ACTIVE CONTROLS P
PAPs 34 ± 7,8 22,6 ± 6,7 0,0001
TAPSE 2,0 ± 0,2 2,2 ± 0,2 0,025
MAPSE 1,49 ± 0,12 1,76 ± 0,08 0,0001
EF 65 ± 4 64 ± 2,7 NS
E/A 1,34 ± 0,4 1,38 ± 0,19 NS
DECT 157 ± 24 163 ± 27 NS
Diastolic dysfunction 5(16) 0(21) 0,01
Pulmonary hypertension 6(16) 0(21) 0,003
REFERENCES:
[1] LeRoy EC. Systemic sclerosis. A vascular perspective. Rheum Dis Clin North Am.
[2] Ibadete Bytci, Left atrial change in early stages of heart failure with preserved ejection fraction. Echocardiography
[3] Sherif F. Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography. Journal of the American Society of Echocardiography
[4] Luke S. Howard, Echocardiographic assessment of pulmonary hypertension: standard operating procedure. European Respiratory Revie
Origen, significado geológico y métodos de estudio de rocas graníticas
No full textFil: Zaffarana, Claudia Beatriz. Universidad Nacional de Rio Negro, Instituto de Investigacion en Paleobiologia y Geologia, CONICET, Consejo Nacional de Investigaciones Cientificas y Tecnicas. Argentina.Fil: Martínez Dopico, Carmen. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Geocronología y Geología Isotopica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Geocronología y Geología Isotopica. Argentina.Fil: Alasino, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de Catamarca. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. Argentina.Fil: D'Eramo, Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rio Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Geología. Argentina.Fil: Pinotti, Lucio. Universidad Nacional de Rio Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Geología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Argentina.La Tierra es un planeta único dentro del Sistema Solar, en parte gracias a la existencia de rocas graníticas. Las rocas graníticas son un componente fundamental de la corteza continental y su origen se debe principalmente a la presencia de agua y al funcionamiento de la tectónica de placas. Los otros planetas rocosos del Sistema Solar al parecer carecen de este tipo de corteza, y solamente tienen corteza oceánica. En ese sentido, la formación de granitoides es el mecanismo principal de diferenciación de la corteza terrestre. El proceso de segregación de los magmas tiene su fuente en la corteza profunda (a más de 30-40 km de profundidad), luego los magmas ascienden y finalmente se emplazan en niveles corticales más someros, entre 10 y 20 km de profundidad. Es decir que los magmas de composición granítica atraviesan entre 10 y 40 km de corteza hasta llegar a su nivel final de emplazamiento. La migración del magma desde la base de la corteza tiene dos consecuencias mayores: por un lado, la fuente, usualmente la corteza inferior como zona de fusión y/o hibridización con magmas del manto, queda deshidratada y restítica; mientras que, por otro lado, la corteza superior se enriquece en elementos incompatibles como los elementos de alta carga y bajo radio iónico (HFSE, “high field strength elements”) y los elementos de baja carga y alto radio (elementos litófilos o LILE, “large ion lithophile elements”), muchos de los cuales son productores de energía por decaimiento radioactivo (p. ej. Th, U y K)
Assessing water surface temperature from Landsat imagery and its relationship with a nuclear power plant
No full textWater temperature is fundamental to understand the functioning of aquatic systems. The objective of this study was to assess the effect of warm water discharge from a nuclear power plant on the water surface temperature (WST) of a reservoir. Using a 6-year Landsat-derived WST dataset, which includes 3 years of the power plant being in operation (2013–2015) and 3 years in which the power plant was not functioning (2016–2018), the effect of the thermal pollution was assessed. The results show that, although the warm water discharge did not reveal a statistically significant increase on the mean WST of the reservoir (p > 0.05), multi-temporal Landsat imagery revealed that the power plant generated a local thermal impact. This was the principal heat flux following a dissipation line that was wide near the cooling channel and expanding towards the rest of the reservoir.Fil: Bonansea, Matias. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; ArgentinaFil: Ferrero, Susana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Matemática; ArgentinaFil: Ferral, Anabella. Comision Nacional de Actividades Espaciales. Instituto de Altos Estudios Espaciales "Mario Gulich"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Ledesma, Micaela. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; ArgentinaFil: German, Alba. Comision Nacional de Actividades Espaciales. Instituto de Altos Estudios Espaciales "Mario Gulich"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Carreño, Joel. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; ArgentinaFil: Rodriguez, Claudia. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; ArgentinaFil: Pinotti, Lucio Pedro. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente; Argentin
Performance of comprehensive complication index and clavien‐dindo complication scoring system in liver surgery for hepatocellular carcinoma
No full textCrustal structure in high deformation zones: Insights from gravimetric and magnetometric studies in the Guacha Corral shear zone (Eastern Sierras Pampeanas, Argentina)
No full textThe Guacha Corral shear zone (GCSZ) is represented by mylonites that were developed under amphibolites facies conditions from migmatitic protoliths. In this contribution, geophysical, petrological and structural data were combined to determine the 3D geometry of the GCSZ. New gravimetric, magnetometric and structural studies, along an E-W profile, were integrated with existing magnetotelluric and seismological data from a representative regional database of the Eastern Sierras Pampeanas. The zonation of different fabrics across the GCSZ suggests that the pre-existing heterogeneities of the protoliths played a key role in governing the degree of metamorphism of different regions. The low gravity anomalies observed in the GCSZ suggest a transitional boundary zone between the migmatitic and mylonitic domains, where highly deformed shear bands are interspersed with undeformed rocks, presenting gradual contacts. The mylonites in this shear zone show a considerably reduced density when compared to the migmatite protoliths. The density of the rocks gradually increases with depth until it reaches that of the protolith. These changes in the gravity values in response to density changes allowed us to infer a listric geometry at depth of the GCSZ. Low gravity anomalies in the profiles, in regions where high density rocks (migmatites) outcrop at the surface, modeled as buried granitic plutons.Fil: Radice, Stefania. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Geología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Lince Klinger, Federico Gustavo. Universidad Nacional de San Juan. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto Geofísico Sismológico Volponi; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; ArgentinaFil: Maffini, María Natalia. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Geología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Pinotti, Lucio Pedro. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Geología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Demartis, Manuel. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Geología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: D'eramo, Fernando Javier. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Geología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Giménez, Mario Jorge. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Geología; ArgentinaFil: Coniglio, Jorge Enrique. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Geología; Argentin
Magnetic fabric of the doleritic dykes in the Panticosa pluton (Pyrenean Axial Zone)
No full textThis work deals with the magnetic fabrics of the doleritic dykes intruded in the Panticosa pluton. The dykes
are grouped in two main families: one with N-S direction and another one E-W, the most common. The
measured magnetic susceptibility values range from 390 10-6SI to 1464 10-6SI, being representative of
paramagnetic rocks with a minor ferromagnetic component. The recorded magnetic foliations and lineations
show a strong structural homogeneity all over the sampling transects. The obliquity between the magnetic
foliations and lineations, and the walls of the dykes, implies that the magma was intruded taken advantage
of an extensional process, oblique to the strike of the dykes. This process could be related with the
regional stress field invoked to explain the intrusion of the Panticosa pluto
A bimodal source for the generation of tonalitic to granitic magmas in a non-subduction-related magmatic belt: An example from the Sierra Chica of Córdoba, Argentina
No full textA notable consensus prevails about the hybrid nature of intermediate calc-alkaline magmatism. Accordingly, petrogenetic models envisage the addition of young mantle material and cortical recycling in those geological settings where intermediate magmas are dominant. Most exhaustively studied examples are: 1) magmatic arcs associated with subduction zone settings where oceanic crust and sediments are introduced into the mantle wedge, and 2) deep crustal sections are pervaded by hot, H2O-rich mantle-derived liquids. Nevertheless, back-arc or foreland terranes of several hundred kilometers in width, frequently characterized by high heat flux, crustal melting, recycling and melt fractionation, are crucial areas to evaluate the generation of intermediate magmatism. The Sierra Chica of Córdoba (Argentina) provides an excellent example to study these processes. The high-grade crustal segment shows metamorphosed pelitic and basaltic protoliths that were part of an old sedimentary succession. We evaluate the evolution of this bimodal source during two consecutive early Paleozoic orogenic periods when it was established as the source area of intermediate to silicic magmatism far from the contemporary magmatic arcs. Field relations and new geochemical and geochronological data revealed the occurrence of two magmatic events during Cambrian and early Ordovician periods. Cambrian migmatization and partial melting (∼528 to 505 Ma) is represented by irregular-shaped monzogranites and tonalites, while early Ordovician magmatism (∼480 Ma) is characterized by dyke-shaped pegmatites and tonalite-trondhjemites. The preservation of two contrasting igneous lineages suggests a genetic linkage between metapelitic and amphibolitic migmatites and between granitic and tonalitic-trondhjemitic partial melts. Coeval with this magmatism, Famatinian tonalitic-trondhjemitic to monzogranitic magmas intruded upper crustal levels in Sierra Chica and other parts of Sierras of Córdoba. Geochemical signatures point to a bimodal (mafic/felsic) source for this intermediate to silica-rich magmatism. The evolution of partial melts studied in the Sierra Chica is depicted on the basis of geochemical projections with fractionation and hybridization models, in order to establish the primary liquids of this Famatinian magmatic belt. Trends defined by Famatinian tonalites, trondhjemites and granodiorites suggest that primary Ca-rich melts (tonalites and trondhjemites of this study) evolved through fractionation of plagioclase (30–50 vol%) compatible with the preservation of inferred co-magmatic Pl-cumulates within these plutonic bodies. Peraluminous granites and monzogranites can be explained by a simple restite unmixing process involving alkali-rich liquids generated in the metapelitic part of the source. The addition (hybridization) of up to 30 vol% of granitic melts to the tonalite-trondhjemite end-member may account for the composition of other Famatinian granodioritic to monzogranitic intrusive rocks from the plutonic belt. The crustal segments of the Sierra Chica have undergone metamorphism and partial melting in out-of-arc settings: the Cambrian fore-arc and the early Ordovician back-arc. The voluminous magmatic belt rooted in the paired metapelitic-amphibolic source area is involved in the origin of intermediate to silicic Famatinian magmatism without significant mass transfer from the mantle and crustal growth, instead it is dominated by crustal melting, recycling and fractionation.Fil: Boffadossi, María Alejandra. Universidad Nacional de Rio Cuarto. Facultad de Cs.exactas Fisicoquimicas y Naturales. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente.; ArgentinaFil: Díaz Alvarado, Juan. Universidad Rey Juan Carlos. Departamento de Biología y Geología; EspañaFil: Pinotti, Lucio Pedro. Universidad Nacional de Rio Cuarto. Facultad de Cs.exactas Fisicoquimicas y Naturales. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente.; ArgentinaFil: Jung, Stefan. Universitat Hamburg. Fakutat Fur Mathematik, Informak Und Naturwissenschaften. Fachbereich Geowissenchatten. Mineralogisch - Petrographisches Institut.; . Universit¨at Hamburg. Mineralogisch - Petrographisches Institut; AlemaniaFil: D'eramo, Fernando Javier. Universidad Nacional de Rio Cuarto. Facultad de Cs.exactas Fisicoquimicas y Naturales. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente.; ArgentinaFil: Pedrera, Antonio. Instituto Geológico y Minero de España; EspañaFil: Millán Martinez, María. Instituto Geológico y Minero de España; EspañaFil: Demartis, Manuel. Universidad Nacional de Rio Cuarto. Facultad de Cs.exactas Fisicoquimicas y Naturales. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente.; ArgentinaFil: Azor, Antonio. Universidad de Granada; EspañaFil: Muratori, María Eugenia. Universidad Nacional de Rio Cuarto. Facultad de Cs.exactas Fisicoquimicas y Naturales. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente. - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Cordoba. Instituto de Ciencias de la Tierra, Biodiversidad y Ambiente.; Argentin
Granitos anatécticos de las Sierras Pampeanas de Córdoba (Argentina): edades U-Pb SHRIMP y estudio LAICP- MS de elementos traza en circón de metamorfismo y cristalización diacrónicos
No full textIn this contribution we present new U-Pb SHRIMP ages and in
situ LA-ICP-MS trace element geochemistry of zircon crystals from
the Río de los Sauces anatectic granite, Córdoba, Argentina. Notable
difference in texture and composition allowed us to identify two
zircon populations in a single granite sample that are interpreted
as reflecting metamorphic and igneous origins. Zircons regarded
as restitic crystals entrained during the melt segregation yielded a
slightly older concordia age of 537.1 ± 4.8 Ma (2σ) than those interpreted
as igneous, dated at 529 ± 6 (2σ) Ma. Inherited metamorphic
zircons are interpreted to represent solid-state growth during high
temperature metamorphism of the Pampean orogeny at the onset
of the anatexis or metamorphic peak. By contrast, igneous zircons
would record the crystallization age of Zr within the Río de los Sauces
granite. The textural, compositional and geochronological data of
both zircon populations suggest that the inception of the anatexis,
the melt segregation and crystallization occurred during a short period
of time of 8 myEn este trabajo se aportan nuevos datos de edades U-Pb SHRIMP
y análisis in situ LA-ICP-MS de elementos traza de circones provenientes
del granito Río de los Sauces, Córdoba, Argentina. A partir
de marcadas diferencias texturales y composicionales se pudieron
identificar dos poblaciones de circones en una misma muestra del
granito, las cuales sugieren orígenes metamórficos e ígneos. Las
edades concordia obtenidas en los circones metamórficos e ígneos
fueron de 537,1 ± 4,8 Ma (2σ) y 529 ± 6 (2σ) Ma, respectivamente. Se
interpreta que los circones metamórficos representan el crecimiento
en estado sólido durante el metamorfismo de alta temperatura de
la orogenia Pampeana, durante el inicio o el clímax de la anatexia.
Por su parte, las edades de los circones ígneos representan la edad
de cristalización del granito Río de los Sauces. Los datos texturales,
composicionales y geocronológicos de ambas poblaciones de circones
sugieren que el inicio de la anatexia, la segregación del fundido
y la cristalización ocurrieron durante un periodo breve de tiempo de
8 ma
Time lag between metamorphism and crystallization of anatectic granites (Córdoba, Argentina)
No full textSHRIMP and LA-ICP-MS analyses carried out on zircons from the Río de los Sauces granite revealed their metamorphic and igneous nature. The metamorphic zircons yielded an age of 537±4.8 (2σ)Ma that probably predates the onset of the anatexis during the Pampean orogeny. By contrast, the igneous zircons yielded a younger age of 529±6 (2σ)Ma and reflected its crystallization age. These data point to a short time lag of ca. 8Myr between the High Temperature (HT) metamorphic peak and the subsequent crystallization age of the granite. Concordia age of 534±3.8 (2σ)Ma, for both types of zircon populations, can be considered as the mean age of the Pampean HT metamorphism in the Sierras de Córdoba
Top-down structures of mafic enclaves within the Valle Fértil magmatic complex (Early Ordovician, San Juan, Argentina)
No full textMagmatic structures related to the mechanical interaction between mafic magmas and granitoids have been studied in the Valle Fértil calc-alkaline igneous complex, Argentina. Excepcional outcrops with vertical walls of more than 300 m high allow us the study of three-dimensional geometries of individual blobs of mafic magma as well as the geometry of pipe-like structures in which mafic microgranular enclaves are concentrated in more than 50 times the normal abundance in the granodiorite mass. The shape of enclaves and pipe-like structures are interpreted as the ressult of top-to-down intrusions of a mafic magma into a granodiorite-tonalite mass. These sinking structures are the result of a reverselly stratified magma chamber with gabbros and diorites at the top and granodiorite-tonalite at the bottom. They may account for most of the structures found in microgranular enclaves and magma mingling zones that characterize calc-alkaline batholiths. Synplutonic intrusions from the top is the only plausible mechanism to account for the observed structures. The model may be of general application to calc-alkaline batholiths characterized by the presence of mafic microgranular enclaves. An implication of these reverselly stratified magma chambers is the presence of a petrological inversion which may be the consequence of cold diapirs emplaced below the mantle wedge in a suprasubduction setting
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