1,128 research outputs found
The Association Between Fear of Falling and Fall Prevention Interventions Offered by an Occupational Therapist in a Geriatric Primary Care Setting
Abstract
Date Presented 4/1/2017
This study demonstrates that occupational therapy fall prevention interventions are beneficial for improving quality of care as part of a coordinated care team within a primary care setting and should further be examined in expanded populations, settings, and interventions.
Primary Author and Speaker: Lydia Royeen
Contributing Authors: Kieran J. Fogarty, Brenda Koverman</jats:p
Media Relations in English Football Clubs
External corporate communications are regarded as a vital function for both the
everyday running and the long-term success of the sport industry in general and the
football industry in particular. However, the examination of media relations in
football, especially in regards to traditional media, appears to attract little research,
regardless of its great impact on corporate reputation and image management. This
study examines how media relations are managed, by investigating the current
practice in English Premier League clubs. The analysis of the practices employed in
the clubs underlines the disparity within them, which is further highlighted by the
various Communications and Media departments’ structures encountered. From
building formal relations between the clubs and traditional media, to developing
clubs’ own media to exclude traditional media from the communications process, or
even sustaining informal personal relations between clubs’ employees and members
of the media, this study illustrates the key media relations practices encountered
within English football clubs
Extracellular Matrix Dynamics in Biology, Bioengineering, and Pathology
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contac
HUMAN GENOME EPIDEMIOLOGY: A SCIENTIFIC FOUNDATION FOR USING GENETIC INFORMATION TO IMPROVE HEALTH AND PREVENT DISEASE
Contributors -- Pt. I. Fundamentals -- Ch. 1. Human genome epidemiology: scope and strategies / Muin J. Khoury, Julian Little, and Wylie Burke -- Ch. 2. Emerging genomic technologies and analytic methods for popu1ation and clinic-based research / Darrell L. Ellsworth and Christopher J. O'Donnell -- Ch. 3. Approaches to quantify the genetic component of and identify genes for complex traits / Patricia A. Peyser and Trudy L. Burns -- Ch. 4. Ethical, legal, and social issues in the design and conduct of human genome epidemiology studies / Laura M. Beskow -- Pt. II. Methods and approaches I: assessing disease associations and interactions -- Ch. 5. Assessing genotypes in human genome epidemiology studies / Karen Steinberg and Margaret Gallagher -- Ch. 6. Statistical issues in the design and analysis of gene- disease association studies / Duncan C. Thomas -- Ch. 7. Facing the challenge of complex genotypes and gene-environment interaction: the basic epidemiologic units in case-control and case-only designs / Lorenzo D. Botto and Muin J. Khoury -- Ch. 8. Inference issues in cohort and case-control studies of genetic effects and gene- environment interactions / Montserrat Garcia-Closas, Sholom Wacholder, Neil Caporaso, and Nathaniel Rothman -- Ch. 9. Applications of human genome epidemiology to environmental health / Samir N. Kelada, David L. Eaton, Sophia S. Wang, Nathaniel R. Rothman, and Muin J. Khoury -- Ch. 10. Reporting and review of human genome epidemiology studies / Julian Little -- Pt. III. Methods and approaches II: assessing genetic tests for disease prevention - - Ch. 11. Epidemiologic approach to genetic tests: population- based data for preventive medicine / Marta Gwinn and Muin J. Khoury -- Ch. 12. Genetic tests in populations: an evidence-based approach / Paolo Vineis -- Ch. 13. ACCE: a model process for evaluating data on emerging genetic tests / James E. Haddow and Glenn E. Palomaki - - Ch. 14. The interface between epidemiology and pharmacogenomics / David L. Veenstra -- Ch. 15. Integrating genetics into randomized controlled trials / John P.A. Joannidis and Joseph Lau -- Ch. 16. Developing guidelines for the clinical use of genetic tests: a U.S. perspective / Linda E. Pinsky, David Atkins, Scott Ramsey, and Wylie Burke -- Ch. 17. Using human genome epidemiologic evidence in developing genetics services: The U.K. experience / Brenda J. Wilson, Jeremy M. Grimshaw, and Neva E. Haites -- Pt. IV. Case studies: using human genome epidemiology information to improve health -- Ch. 18. Parlioxonase polymorphisms and susceptibility to organophosphate pesticides / Kathryn Battuello, Clement Furlong, Richard Fenske, Melissa A. Austin, and Wylie Burke -- Ch. 19. Factor V Leiden, oral contraceptives, and deep vein thrombosis / Jan P. Vandenbroucke, Frits R. Rosendaal, and Rogier M. Bertina - - Ch. 20. Methylenetetrahydrofolate reductase gene (MTHFR), folate, and colorectal neoplasia / Linda Sharp and Julian Little -- Ch. 21. Apolipoprotein E and Alzheimer disease / Richard Mayeux -- Ch. 22. Immunogenetic factors in chronic beryllium disease / Erin C. McCanlies, Michael E. Andrew, and Ainsley Weston -- Ch. 23. Fragile X Syndrome: from gene identification to clinical diagnosis and population screening / Dana C. Crawford and Stephanie L. Sherman - - Ch. 24. The Connexin connection: from epidemiology to clinical practice / Aileen Kenneson and Coleen Boyle -- Ch. 25. Genetic and environmental factors in cardiovascular disease / Molly S. Bray - - Ch. 26. BRCA1/2 and the prevention of breast cancer / Jenny Chang-Claude -- Ch. 27. The role of chemokine and chemokine receptor genes in HIV-1 infection / Thomas R. O'Brien -- Ch. 28. Hereditary hemochromatosis / Giuseppina Imperatore, Rodolfo Valdez, and Wylie Burke -- Ch. 29. Genetic testing of railroad track workers with carpal tunnel syndrome / Paul A. Schulte and Geoffrey Lomax -- Inde
Granular flow, segregation and agglomeration in bladed mixers
A large number of industrial processes involve the transport, mixing and storage of particulate systems. While prevalent in industry, particulate processes are commonly plagued by problems due to the complex rheology of these systems. In this work, the behavior of granular materials in a bladed mixer, an industrially relevant geometry, was investigated using computational and experimental techniques. Experimental flows were characterized via Particle Image Velocimetry and image analysis. Discrete element simulations were carried out to examine the effect of a wide range of system parameters. Particulate flows in bladed mixers were found to be periodic with complex flow patterns developing throughout the particle bed. Cohesionless flows were initially studied. For monodisperse flows, two distinct flow regimes were observed: a quasi-static regime where blade speed provides the time scale for momentum transfer and an intermediate regime where stresses scale linearly with blade speed. Particle and wall roughness were found to significantly affect bladed mixer flows. Systems with higher roughness are characterized by enhanced particle motion and mixing. Simple scaling relationships were observed for monodisperse flows in the quasi-static regime. Particle velocities and diffusivities were found to scale linearly with mixer size and blade speed, while stresses scaled linearly with particle bed weight. In polydisperse flows, size segregation was found to occur due to sieving. However, it was found that the extent of segregation can be reduced by introducing intermediate particle sizes in between the smallest and largest particles. Finally, wet particle flows were examined. At low moisture contents, enhanced particle velocities and mixing kinetics were observed in comparison to dry flows. However, at higher moisture contents, particle velocities and mixing rates were observed to decrease. Wet particle flows were characterized by the formation of particle agglomerates. Agglomerate formation led to an increase in particle bed roughness which significantly influenced macroscopic and microscopic flow properties. These findings contribute to the understanding of granular behavior in complex systems. Improved understanding of granular flows will enable the development of first-principles based models which can assist in the design and scale-up of bladed mixer operations and the identification of critical processes parameters.Ph.D.Includes bibliographical referencesIncludes vitaby Brenda Rem
Customs Censorship and the Charter: The Little Sisters Case
Little Sisters Book and Art Emporium is Vancouver's only bookstore specializing in gay and lesbian literature. Little Sisters argued that the provisions of the Customs Act and Customs Tariff that together empower officials to stop obscene representations at the border constitute unreasonable restrictions on freedom of expression and equality rights protected by section 2(b) and section 15 of the Charter.
In our view, Justice Smith's findings on the importance of sexual expression to the gay and lesbian community, and on the disproportionate impact of Customs censorship on gay and lesbian materials, ought to have led to the conclusion that the legislation in its effects violates section 15. On the question of whether the violation of section 2(b) was a reasonable limit, we believe that Smith J. ought to have exercised greater caution in assuming that the reasoning in Butler could be extended, without hesitation or problematization, to gay and lesbian, sexual imagery. Many of the publications suppressed by Customs are integral to the cultural and political identity of a disadvantaged and stigmatized sexual minority. Thus their distribution fosters goals that lie at the heart of the Charter's protection of expression and equality interests in sections 2(b) and 15, respectively. For this reason, we believe that Smith J. erred in not holding the government to a rigourous standard of justification at the section 1 stage of the analysis. We have also taken issue with Smith J.'s failure to implicate the procedural deficiencies of the Customs Act in the Charter violations identified by the evidence. In our view, at the very least, a system of administrative censorship cannot constitute a minimal impairment of Charter rights if it makes little or no attempt to ensure that decisions will be made expeditiously by expert decision-makers who have the ability to receive evidence of a publication's merits
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Approaches exploiting trait distribution extremes may be used to identify loci associated with common traits, but it is unknown whether these loci are generalizable to the broader population. In a genome-wide search for loci associated with the upper versus the lower 5th percentiles of body mass index, height and waist-to-hip ratio, as well as clinical classes of obesity, including up to 263,407 individuals of European ancestry, we identified 4 new loci (IGFBP4, H6PD, RSRC1 and PPP2R2A) influencing height detected in the distribution tails and 7 new loci (HNF4G, RPTOR, GNAT2, MRPS33P4, ADCY9, HS6ST3 and ZZZ3) for clinical classes of obesity. Further, we find a large overlap in genetic structure and the distribution of variants between traits based on extremes and the general population and little etiological heterogeneity between obesity subgroups
Positive youth development programs build civically engaged leaders
Youth participation in meaningful and purposive civic organizations and activities not only impacts the participants’ development, but also influences their involvement in their communities both today and in the future. The combination of the two studies included in this dissertation examine just that. Both studies were conducted utilizing original research by the author utilizing the frameworks of Positive Youth Development (PYD) and experiential learning. The first study is a program evaluation of the Iowa State 4-H Council, assessing the participants’ outcomes in the common measure Life Skill constructs critical to the development of civically engaged individuals, including: citizenship, communication, leadership, and learning skills. These outcomes were identified through responses by the youth on a set of common Life Skill measures, as well as selected open-ended questions.
Study two examines the development of civic engagement or citizenship skills and contribution among youth or adolescents as part of PYD and explores the long-term civic engagement impact of those experiences for participating individuals. The members of the study are now young adults reflecting on and connecting their youth experiences to their involvement today. This was conducted through a phenomenological approach utilizing interviews of fourteen former State 4-H Council members now 25-35 years-old.
One can observe themes between the two studies in regard to the development of civic engagement and leadership within youth and the identified best practices to foster that development. The State 4-H Council is one unique experience, but can play a significant role in crystallizing and increasing the depth of skill and learning from the opportunities youth have had at a local level by expanding the scope of responsibility for participants. Empowering youth to have a voice and share in decision-making builds confidence in the youth themselves and their ability to make decisions, regardless of the PYD organization or group the youth belonged. Additionally, it gives them real and meaningful practice in doing so in ways that are significant and long-lasting. It also develops a life-long commitment and belief that not only can make a difference in their communities and beyond, but in fact, they should.</p
Microbial extracellular polymeric substances in the environment, technology and medicine
Microbial biofilms exhibit a self-produced matrix of extracellular polymeric substances (EPS), including polysaccharides, proteins, extracellular DNA and lipids. EPS promote interactions of the biofilm with other cells and sorption of organics, metals and chemical pollutants, and they facilitate cell adhesion at interfaces and ensure matrix cohesion. EPS have roles in various natural environments, such as soils, sediments and marine habitats. In addition, EPS are relevant in technical environments, such as wastewater and drinking water treatment facilities, and water distribution systems, and they contribute to biofouling and microbially influenced corrosion. In medicine, EPS protect pathogens within the biofilm against the host immune system and antimicrobials, and emerging evidence suggests that EPS can represent potential virulence factors. By contrast, EPS yield a wide range of valuable products that include their role in self-repairing concrete. In this Review, we aim to explore EPS as a functional unit of biofilms in the environment, in technology and in medicine.</p
Little Buckaroo Royalty
The Buckaroo Rodeo royalty are seated on their horses in front of the grandstands at the Uintah County Fairgrounds. From left are Christene McNeill, attendant; Tracy Durfee, queen and Brenda Durfee, attendant
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