4,695 research outputs found

    Local Author Book Talk: Meet D.M. Pulley author of The Dead Key

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    Local Author D.M. Pulley, author of The Dead Key. 2014 Winner — Amazon Breakthrough Novel Award — Grand Prize and Mystery & Thriller Fiction Winner. It’s 1998, and for years the old First Bank of Cleveland has sat abandoned, perfectly preserved, its secrets only speculated on by the outside world.--Source Amazon.com These books and all Friends of the Library 2021/2022 book selections are on sale at Viking Outfitters, located in the CSU Student Center

    Canceled: Local Author Book Talk: Meet D.M. Pulley author of The Dead Key

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    This event has been canceled due to the Coronavirus. Meet Local Author D.M. Pulley, author of The Dead Key. 2014 Winner — Amazon Breakthrough Novel Award — Grand Prize and Mystery & Thriller Fiction Winner. It’s 1998, and for years the old First Bank of Cleveland has sat abandoned, perfectly preserved, its secrets only speculated on by the outside world.--Source Amazon.com The books titled The Dead Key, No one’s Home, Unclaimed Victim, and The Buried Book will be available for sale by Viking Outfitters at the event. These books and all Friends of the Library 2019/2020 book selections are on sale at Viking Outfitters, located in the CSU Student Center

    M-032 Reconnaissance geologic map of Lima Mountain quadrangle, Cook County, Minnesota

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    Scale 1:24,000.Davidson, D.M. Jr.. (1977). M-032 Reconnaissance geologic map of Lima Mountain quadrangle, Cook County, Minnesota. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/59938

    Perfil hematológico do Sorubim lima (Siluriformes, pimelodidae) de cativeiro: intervalos de referência, morfologia e citoquímica celular

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    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias. Programa de Pós-Graduação em Aquicultura, Florianópolis, 2013A hematologia consiste em uma análise rápida e prática para auxiliar o diagnóstico do desequilíbrio homeostático em peixes. Este estudo determinou os intervalos de referência sanguíneos em importante bagre nativo da América do Sul, Sorubim lima, criado na região do pantanal e descreve as características morfológicas e citoquímicas das células. Um total de 92 peixes de piscicultura foram examinados para determinação dos intervalos de referência 25 - 75%, concentração de proteínas plasmáticas totais, hemoglobina, número total de eritrócitos (ERT), hematócrito, volume corpuscular médio (VCM), concentração da hemoglobina corpuscular média (CHCM), trombócitos totais e leucócitos totais (LEU). PAS com amilase salivar, azul de bromofenol, sudan black B e azul de toluidina (metacromasia) foram as colorações citoquímicas empregadas para sinalizar glicogênio, proteínas, lipídeos e núcleos em trombócitos e leucócitos. Nas extensões sanguíneas, monócitos, linfócitos, neutrófilos, basófilos, eosinófilos, LG-PAS e trombócitos foram observados. Resultados semelhantes a outros siluriformes foram observados nas características morfológicas de neutrófilos e eusinófilos. ERT, hematócrito e VCM apresentaram índices com as menores variações, em relação a demais pimelodídeos. Diferentemente de outros peixes siluriformes, S. lima apresentou simultaneamente eosinófilos e basófilos circulantes. Abstract : Haematology consists in a rapid and practical analysis to assist the diagnosis of fish homeostatic imbalance. This study determined the blood reference intervals in an important native South American catfish farmed in the brazilian pantanal wetland, Sorubim lima, and describes the morphological and cytochemical characteristics of cells. A total of 92 fish reared in a fish farm were examined for reference intervals 25 - 75% of total plasmatic protein, hemoglobin, red blood cell count (RBC), hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC) and total thrombocyte and leukocyte count (WBC). PAS with salivary amylase, bromophenol blue, sudan black B and toluidine blue (metacromasy) were the cytochemical stains employed to signal glycogen, proteins, lipids and nuclei in thrombocytes and leucocytes. In the blood smears, monocytes, lymphocytes, neutrophils, basophils, eosinophils, LG-PAS and thrombocytes were observed. Siluriforms similar results were observed in neutrophils and eosinophils morphology. Compared to other pimelodids, RBC, hematocrit and MCV showed index lowest variation. Differently from other siluriforms fishes, S. lima showed the concomitant presence of circulating eosinophils and basophils

    Gender differences in self-reported late effects, quality of life and satisfaction with clinic in survivors of lymphoma

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    Objectives: gender differences in perceived vulnerability to late effects and views about follow-up among cancer survivors have received little attention. As lymphoma affects both genders similarly, we compared the consequences of cancer (late effects, perceived vulnerability and quality of life (health-related quality of life (HRQoL)), and satisfaction with clinic visits between genders.Methods: a cohort of 115 younger adults (18–45 years, >5 years disease-free survival), who had been treated for lymphoma participated. Questionnaires (n = 91) were completed before and after (n = 62) routine consultant-led appointments. Survivors (n = 24) without appointments were recruited by post. Questionnaires included HRQoL, late effects, perceived vulnerability, issues survivors wanted to discuss and reported discussing in clinic, time waiting in clinic and consultation satisfaction.Results: there were no gender differences in number of self-reported late effects or perceived vulnerability. Men with more late effects reported worse psychological HRQoL (r = 0.50, p<0.001). While men wanted to discuss more topics than they did, women were able to discuss the topics they wanted (ANOVA, p = 0.01). Multiple regression analyses showed a shorter wait in clinic (r = ?0.46, p = 0.009) and discussing more topics (r = 0.34, p = 0.06) explained 30.6% of the variance in consultation satisfaction for men.Conclusions: issues surrounding follow-up provision are increasingly important given the length of survival in young adults following treatment for lymphoma. Men may experience poor psychological well-being due to distress about unanswered concerns. Consideration of their concerns should be prioritised, given that satisfaction and ultimately continued attendance at clinic and HRQoL may be dependent on the extent to which follow-up meets survivors' expectation

    Na-ca Exchange And Ca Fluxes During Contraction And Relaxation In Mammalian Ventricular Muscle

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    There are four cellular Ca transport systems which compete to remove Ca from the myoplasm in mammalian ventricular myocytes. These are 1) the SR Ca-ATPase, 2) the sarcolemmal Na-Ca exchange, 3) the sarcolemmal Ca-ATPase and 4) the mitochondrial Ca uniporter. Using multiple experimental approaches we have evaluated the dynamic interaction of these systems during the normal cardiac contraction-relaxation cycle. The SR Ca-ATPase and Na-Ca exchange are clearly the most important, quantitatively; however, the relative roles vary in a species-dependent manner. In particular, the SR is much more strongly dominant in rat ventricular myocytes, where ~ 92% of Ca removal is via SR Ca-ATPase and only 7% via Na-Ca exchange during a twitch. In other species (rabbit, ferret, cat, and guinea pig) the balance is more in the range of 70% SR Ca-ATPase and 25-30% Na-Ca exchange. Ferret ventricular myocytes also exhibit an unusually strong sarcolemmal Ca-ATPase. During the steady state the same amount of Ca must leave the cell as enters over a cardiac cycle. This implies that 25-30% of the Ca required to activate contraction must enter the cell, and experiments demonstrate that this amount of Ca may be supplied by the L-type Ca current.779430442Bers, D.M., (1991) Excitation-Contraction Coupling and Cardiac Contractile Force, pp. 1-258. , (Single author monograph.) Kluwer Academic Press. Dordrecht, NetherlandsSutko, J.L., Willerson, J.T., Ryanodine alteration of the contractile state of rat ventricular myocardium. Comparison with dog, cat and rabbit ventricular tissues (1980) Circ. Res., 46, pp. 332-343Bers, D.M., Ca influx and SR Ca release in cardiac muscle activation during postrest recovery (1985) Am. J. Physiol., 248, pp. H366-H381Bers, D.M., Mechanisms contributing to the cardiac inotropic effect of Na-pump inhibition and reduction of extracellular Na (1987) J. Gen. Physiol., 90, pp. 479-504Bers, D.M., Christensen, D.M., Nguyen, T.X., Can Ca entry via Na-Ca exchange directly activate cardiac muscle contraction? (1988) J. Mol. Cell. Cardiol., 20, pp. 405-414Beuckelmann, D.J., Wier, W.G., Mechanism of release of calcium from sarcoplasmic reticulum of guinea pig cardiac cells (1988) J. Physiol., 405, pp. 233-255Fabiato, A., Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell (1985) J. Gen. Physiol., 85, pp. 247-290Leblanc, N., Hume, J.R., Sodium current-induced release of calcium from cardiac sarcoplasmic reticulum (1990) Science, 248, pp. 372-376Levi, A.J., Spitzer, K.W., Kohmoto, O., Bridge, J.H.B., Depolarization-induced Ca entry via Na-Ca exchange triggers SR release in guinea pig cardiac myocytes (1994) Am. J. Physiol., 266, pp. H1422-H1433Kohmoto, O., Levi, A.J., Bridge, J.H.B., Relation between reverse sodium-calcium exchange and sarcoplasmic reticulum calcium release in guinea pig ventricular cells (1994) Circ. Res., 74, pp. 550-554Bassani, R.A., Bassani, J.W.M., Bers, D.M., Mitochondrial and sarcolemmal Ca transport can reduce [Ca]i during caffeine contractures in rabbit cardiac myocytes (1992) J. Physiol., 453, pp. 591-608Bassani, J.W.M., Bassani, R.A., Bers, D.M., Relaxation in rabbit and rat cardiac cells: Species-dependent differences in cellular mechanisms (1994) J. Physiol., 476, pp. 279-293Bassani, R.A., Bassani, J.W.M., Bers, D.M., Relaxation in ferret ventricular myocytes: Unusual interplay among calcium transport systems (1994) J. Physiol., 476, pp. 295-308Bers, D.M., Bridge, J.H.B., Relaxation of rabbit ventricular muscle by Na-Ca exchange and sarcoplasmic reticulum Ca-pump: Ryanodine and voltage sensitivity (1989) Circ. Res., 65, pp. 334-342Bridge, J.H.B., Relationships between the sarcoplasmic reticulum and transarcolemmal Ca transport revealed by rapidly cooling rabbit ventricular muscle (1986) J. Gen. Physiol., 88, pp. 437-473Bers, D.M., Bridge, J.H.B., Spitzer, K.W., Intracellular Ca transients during rapid cooling contractures in guinea-pig ventricular myocytes (1989) J. Physiol., 417, pp. 537-553Bers, D.M., Lederer, W.J., Berlin, J.R., Intracellular Ca transients in rat cardiac myocytes: Role of Na/Ca exchange in excitation-contraction coupling (1990) Am. J. Physiol., 258, pp. C944-C954Hryshko, L.V., Stiffel, V.M., Bers, D.M., Rapid cooling contractures as an index of SR Ca content in rabbit ventricular myocyte (1989) Am. J. Physiol., 257, pp. H1369-H1377Hove-Madsen, L., Bers, D.M., SR Ca uptake and thapsigargin sensitivity in permeabilized rabbit and rat ventricular myocytes (1993) Cir. Res., 73, pp. 820-828Bassani, J.W.M., Bassani, R.A., Bers, D.M., Twitch-dependent SR Ca accumulation and release in rabbit ventricular myocytes (1993) Am. J. Physiol., 265, pp. C533-C540Bassani, R.A., Bers, D.M., Rate of diastolic Ca release from the sarcoplasmic reticulum of intact rabbit and rat ventricular myocytes (1995) Biophys. J., 68, pp. 2015-2022Bassani, J.W.M., Yuan, W., Bers, D.M., Fractional SR Ca release is altered by trigger Ca and SR Ca content in cardiac myocytes (1995) Am. J. Physiol., 268, pp. 1313-1319Gatto, C., Milanick, M.A., Inhibition of the red blood cell calcium pump by eosin and other fluorescein analogues (1993) Am. J. Physiol., 264, pp. C1577-C1586Gatto, C., Hale, C.C., Milanick, M.A., Eosin, a potent inhibitor of the plasma membrane Ca pump, does not inhibit the cardiac Na-Ca exchanger (1995) Biochemistry, 34, pp. 965-972Bassani, R.A., Bassani, J.W.M., Bers, D.M., Relaxation in ferret ventricular myocytes: Role of the sarcolemmal Ca ATPase (1995) Pflüg. Arch., 430, pp. 573-579Hove-Madsen, L., Bers, D.M., Passive Ca buffering and SR Ca uptake in permeabilized rabbit ventricular myocytes (1993) Am. J. Physiol., 264, pp. C677-C686Negretti, N., O'Neill, S.C., Eisner, D.A., The relative contributions of different intracellular and sarcolemmal systems to relaxation in rat ventricular myocytes (1993) Cardiovasc. Res., 27, pp. 1826-1830Crespo, L.M., Grantham, C.J., Cannell, M.B., Kinetics, stoichiometry and role of the Na-Ca exchange mechanism in isolated cardiac myocytes (1990) Nature, 345, pp. 618-621Puglisi, J.L., Bassani, R.A., Bassani, J.W.M., Amin, J.N., Bers, D.M., Temperature and the relative contributions of Ca transport systems in cardiac myocyte relaxation (1996) Am. J. Physiol., , In pressDelbridge, L.M., Bassani, J.W.M., Bers, D.M., Steady-state twitch Ca fluxes and cytosolic Ca buffering in rabbit ventricular myocytes (1996) Am. J. 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    Beyond Lesson Studies and Design Experiments: Using theoretical tools in practice and finding out how they work

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    This paper aims to illustrate how fruitful insights into the link between school teaching practice and student learning outcomes can be theoretically grounded by the variation theory from the field of phenomenography; and from this framework demonstrate how a 'pedagogy of awareness' can be implemented in the classroom. In this study, five teachers and 162 students at Primary Four level of school education in Hong Kong participated and the practice of the 'learning study' was adopted. By comparing the results of pre- and posttests, a significant gain was observed in the students learning outcomes.

    Speurplanet.nl onderdeel van Moerstaal: BSc Project Computer Science / Software Technology IN3700

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    Het project bestond uit het vinden van een oplossing om het huidige speurplanet.nl te verbeteren dan wel te vernieuwen. Speurplanet is een website waar gebruikers (tweede hands) artikelen kunnen verkopen en kopen. De opdrachtgever wil het huidige speurplanet.nl vervangen. Het huidige speurplanet.nl moet worden vernieuwd/vervangen, omdat de huidige layout en implementatie niet meer aan de eisen voldoen. Speurplanet is een onderdeel van Moerstaal en D.M. Media. Het bedrijf Moerstaal is een provider van email adressen, homepages en domeinnamen en D.M. Media is een op email gericht marketing bureau.Software EngeneeringElectrical Engineering, Mathematics and Computer Scienc

    Oncideres modesta Dillon & Dillon 1946

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    Oncideres modesta Dillon & Dillon, 1946 Distribution. BRAZIL (Pará, Bahia, and Minas Gerais). Material examined. 1 specimen, BRAZIL: “ BAHIA: Ipecaetá, Cavungê, Rancho Alto da Boa Vista, 12°14′55”S, 38°20′17”W, 189m, 15–29.ix.2018, Malaise trap, Lima, D.M. leg.” (MZFS); 1 specimen: “ Ipecaetá, Cavungê, Rancho Alto da Boa Vista, 12°14′55”S, 38°20′17”W, 189m, Armadilha luminosa, 26.i.2020, Lima, D.M. & Ferreira, G.S. leg.” (MZFS); 3 specimens: “ Ipecaetá, Cavungê, Rancho Alto da Boa Vista, 12°14′55”S, 38°20′17”W, 189m, Armadilha luminosa, 13–12.xii.2020, Lima, D.M. leg.” (MZFS).Published as part of Ferreira, Gabriel Dos Santos, Ferreira, André Da Silva & Bravo, Freddy, 2023, Annotated checklist of Cerambycidae (Coleoptera: Chrysomeloidea) from the Brazilian semi-arid region, with new species and new geographic records, pp. 1-81 in Zootaxa 5235 (1) on page 73, DOI: 10.11646/zootaxa.5235.1.1, http://zenodo.org/record/761030

    Metáforas biológicas combinadas para projeto de redes neurais artificiais

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    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós -Graduação em Computação.A Computação Evolucionária (CE) tem sido utilizada na área de Redes Neurais Artificiais (RNAs) para evolução de três grandes constituintes: pesos das conexões, arquiteturas e regras de aprendizado. A evolução de arquiteturas possibilita o projeto automático de Redes Neurais Artificiais (RNAs), permitindo adapta-las para diferentes tarefas sem a intervenção humana. O objetivo desta pesquisa é introduzir uma metodologia a mais plausível biologicamente, que permita gerar RNAs com boa capacidade de generalizção, pequeno erro e grande tolerância a ruídos. Para isso três metáfora biológicas foram usadas: Algoritmos Genéticos, Sistemas de Lindenmayer e RNAs. Testou-se quatro classes de problemas: XOR, paridade, problema das lâmpadas e botões e as linguagens de Tomita. O método é superior em relação aos outros, pois aumenta o paralelismo implícito do algoritmo genético e pelos aspectos de plausibilidade biológica. O sistema gera arquiteturas mínimas satisfatórias que resolvem determinadas tarefas, reduzindo os custos de projeto e aumentando o desempenho das redes neurais obtidas. Finalmente sugerem-se estratégias racionais que podem fornecer uma eficiência adicional ao algoritmo genético tradicional
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