308,194 research outputs found

    Kuo 2014 genetics data sets

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    Four spreadsheets representing raw datasets supporting the following publication: Kuo, H.K, McMahan, S., Rota, C.P., Kohl, K.P., and Sekelsky, J. (2014) Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases. Genetics

    Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV

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    The prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region

    Kuo-2014-Genetics-Fig4

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    These primary data are summarized and discussed in Kuo et al., Genetics (2014). The second tab has data on mitotic recombination in the male germline. The genotype of the males is shown in the top row. Each was mated to st e virgin females and progeny were scored for st and Sb. Note that the phase of these markers changes between crosses

    Kuo-2014-Genetics-Fig2

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    These primary data are summarized and discussed in Kuo et al., Genetics (2014). The first two sheets contain raw counts of progeny of crosses of net dppd-ho dp b pr cn / + virgin females to net dppd-ho dp b pr cn males. Progeny were scored as parental or wild-type (the two classes of each are not separated here; for example, flies that have all six recessive phenotypes are grouped with those that are wild-type for all [both parental classes]). At the bottom of each are the totals and calculations of centiMorgans (cM) and cM per megabase pair (cM / Mb). Fancm mutants were counted 07/27/2013-08/27/2013; wild-type in 2011. The last tab has mitotic recombination in the male germline. The genotype of the males is shown in the top row. Each was mated to st e virgin females and progeny were scored for st and Sb. Note that the phase of these markers changes between crosses

    Kuo-2014-Genetics-Fig3

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    These primary data are summarized and discussed in Kuo et al., Genetics (2014). Data in this file are from the P{wa} assay, first published in Adams et al., Science (2002), DOI: 10.1126/science.1077198 . The first tab has counts of progeny from each vial. As in other uses of this assay, only daughters that did not recieve the transposase chromosome (Cy+) were scored. Since the Df(3R)ED6058 chromosome has w+ on it, only progeny that recieved a Sbchromosome were scored. f red = frequency of red-eyed flies f yellow = frequency of yellow-eyed flies The last tab has molecular analysis of synthesis and/or deletion in the yellow-eyed daughters. Each row represents presence (+) or absence (-) of a PCR product in white-eyed sons of yellow-eyed progeny. Each yellow-eyed progeny came from a different vials (f numbers are Fancm, c numbers are control). Distance of furthers primer from left or right end of the element is indicated. Primers used are listed

    Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of meson decays to J/ψη and J/ψη′

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    First evidence of the B 0 → J / ψ ω decay is found and the B s 0 → J / ψ η and B s 0 → J / ψ η ′ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb -1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The branching fractions of these decays are measured relative to that of the B 0 → J / ψ ρ 0 decay:frac(B (B 0 → J / ψ ω), B (B 0 → J / ψ ρ 0)) = 0.89 ± 0.19 (stat) - 0.13 + 0.07 (syst),frac(B (B s 0 → J / ψ η), B (B 0 → J / ψ ρ 0)) = 14.0 ± 1.2 (stat) - 1.5 + 1.1 (syst) - 1.0 + 1.1 (frac(f d, f s)),frac(B (B s 0 → J / ψ η ′), B (B 0 → J / ψ ρ 0)) = 12.7 ± 1.1 (stat) - 1.3 + 0.5 (syst) - 0.9 + 1.0 (frac(f d, f s)), where the last uncertainty is due to the knowledge of f d / f s, the ratio of b-quark hadronization factors that accounts for the different production rate of B 0 and B s 0 mesons. The ratio of the branching fractions of B s 0 → J / ψ η ′ and B s 0 → J / ψ η decays is measured to befrac(B (B s 0 → J / ψ η ′), B (B s 0 → J / ψ η)) = 0.90 ± 0.09 (stat) - 0.02 + 0.06 (syst)

    Kuo-2014-Genetics-Fig1

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    The raw data in these sheets are summarized and discussed in Kuo et al., Genetics (2014). Sheets contain raw counts of crosses either treated or untreated with the designated DNA damaging agents HN2 = the nitrogen mustard mechloramin MMS = methane methylsulfonate IR = ionizing radiation (gamma rays from a 137Cs source) In all cases, control progeny carry a balancer that is wild-type for the genes being tested and that carries the Sb dominant marker; therefore, control progeny have stubble bristles and experimental progeny have wild-type bristles. "Relative" (blue columns) are survival of mutants relative to survival of wild-type flies. We also attempted to approximate overall survival, as described on the last sheet. Most experiments had 2 or 3 technical replicates (dosings on different days), each with 8-10 biological replicates (different vials). Vials with fewer than 20 progeny were excluded from this analysis. For these reasons, vial numbers may be discontiguous and repeated in a single experiment. These experiments were performed in 2011-2013
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