122 research outputs found
Automated Summarization of Bug Reports to Speedup Software Development/Maintenance Process by Using Natural Language Processing (NLP)
No full textDevelopers may benefit much from bug reports as they work on new features. However, it might be challenging to make use of these artifacts in the given time owing to the massive size of bug repositories. One strategy to aid developers is to give concise summaries of these reports, focusing on the most relevant information. After deciding if this report is what\u27s needed, you may go into the specifics. With the development of text mining tools, several considerable methods have been developed to produce efficient summaries for bug reports. In this research, we present an extractive-based technique that makes use of language embedding to generate summaries of bug reports. In comparison to prior state-of-the-art methods, our rouge-1 and rouge-2 outcomes for bug report summarization are far better
Integrated Nutrient Management for Improving, Fertilizer Use Efficiency, Soil Biodiversity and Productivity of Wheat in Irrigated Rice Wheat Cropping System in Indo-Gangatic Plains of India
No full textSCP-IoT: Enhancing IoT Communication Security Against Routing Attacks
No full textThe Internet of Things (IoT) needs to be protected while in transmission. Insecure Internet of Things equipment connectivity can direct to security breaches. As a result, third parties can get access and make changes in order to cause problems for things connected in the system. In order to address these difficulties, the IoT communication security needs to be addressed. A new strategy named "secure communication utilising cryptographic approaches for IoT" was presented in this research to deal with this problem. There are three parts to the model, which is called the "safe communication protocol for IoT." First, the initiator sends a connection request to the respondent with the source identification and a true cryptography nonce to initiate the communication. Secondly, the responder examines the nonce\u27s freshness and the source\u27s identity when it receives a request. After that, the responder uses KDH to compute and deliver the MAC result for the SRC ID as part of the Finish message to the initiator. Few current strategies, including developing constrain fuzzy routing principles, were evaluated and compared to the proposed model. Prior to this study, the most important metrics were the MLR and MDR ratios, the spectrum utilisation rate, the network lifetime, and the utilisation rate
Moving object detection using modified GMM based background subtraction
No full textAcademics have become increasingly interested in creating cutting-edge technologies to enhance Intelligent Video Surveillance (IVS) performance in terms of accuracy, speed, complexity, and deployment. It has been noted that precise object detection is the only way for IVS to function well in higher level applications including event interpretation, tracking, classification, and activity recognition. Through the use of cutting-edge techniques, the current study seeks to improve the performance accuracy of object detection techniques based on Gaussian Mixture Models (GMM). It is achieved by developing crucial phases in the object detecting process. In this study, it is discussed how to model each pixel as a mixture of Gaussians and how to update the model using an online k-means approximation. The adaptive mixture model's Gaussian distributions are then analyzed to identify which ones are more likely to be the product of a background process. Each pixel is categorized according to whether the background model is thought to include the Gaussian distribution that best depicts it
Not Available
No full textNot AvailableThe field experiment was conducted during rabi season of 2011-12 and 2012-13 C.S. Azad University of
Agriculture and Technology, Kanpur with the objectives to find out the combined effect of organic and
inorganic fertilizers on grain yield, productivity and profitability of wheat crop. The 10 treatments were
tested in Randomized Block Design with three replication. T1- Control, T2 - RDF (150:60:40 NPK Kg/ha), T3
- 125% RDF, T4 - RDF + Vermicompost @ 2.5 t/ha, T5 - RDF + Vermicompost @ 5 t/ha, T6 - RDF + FYM @ 5t/
ha, T7 - RDF + FYM @ 10 t/ha, T8 - RDF + Vermicompost @ 2.5 t/ha + Azotobacter, T9 - RDF + FYM @ 5t/ha
+ Azotobacter, and T10 - RDF + Vermicompost @ 2.5 t/ha + FYM @ 5 t/ha + Azotobacter. Result showed
that the treatment T10 produced higher yield attributes and grain yield than rest of the treatment. The
higher yield led to higher NPK uptake by wheat. Further, the available NPK and Organic Carbon (%)
content of soil also increased in above integration of organic and inorganic fertilizer along with bio-fertilizer
strain over control as well as chemical fertilizers alone. The highest net return (INR/ha 53882) and benefit
: cost (1.23) was also obtained from the application of RDF + Vermicompost @ 2.5 t/ha + FYM @ 5 t/ha +
Azotobacter and lowest from control (21873) and (0.74), respectively.Not Availabl
Growth specificity of vertical ZnO nanorods on patterned seeded substrates through integrated chemical process
No full text10.1016/j.matchemphys.2011.12.076Materials Chemistry and Physics1331126-134MCHP
A compendium of key climate smart agriculture practices in intensive cereal based systems of South Asia
No full text42 page
Melaninas quimicamente modificadas: preparação, caracterização, citotoxicidade, atividade antioxidante e interação com espécies catiônicas
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015.Melaninas são bio-oligômeros de ocorrência natural que podem ser encontradas na pele, no cabelo, nos olhos, no cérebro e também em alguns animais marinhos. Entretanto, a extração das melaninas naturais nem sempre é viável devido ao custo elevado dos reagentes utilizados e normalmente obtém-se um baixo rendimento no processo. Neste contexto, destacam-se as melaninas sintéticas, que podem ser produzidas em laboratório com um custo mais baixo e considerável rendimento.Um dos precursores das melaninas sintéticas é o L-3,4-dihidroxifenilalanina conhecido como L-DOPA que livre em condições reacionais produz a eumelanina, responsável pela coloração escura e em presença de cisteína produz a feomelanina, que dá origem a coloração mais clara, esses precursores se agregam entre 3 a 9 unidades indol para formar a estrutura oligomérica da melanina.Neste contexto, este trabalho tem por objetivo descrever a preparação, purificação e caracterização de melaninas quimicamente modificadas pelos aminoácidos serina, treonina e cisteína (feomelaninas), a fim de se obter os compostos ser-DOPA, thr-DOPA e cys-DOPA respectivamente e seus complexos de Cu(II) e Zn(II), bem como descrever as interações com o corante catiônico azul de metileno avaliando suas toxicidades e atividades antioxidantes.A caracterização espectroscópica das melaninas modificadas mostrou a presença de três grupamentos majoritários: ácido carboxílico, quinona-imina e catecol. Estudos em solução por titulação potenciométrica mostraram a presença do grupamento tiol na melanina cys-DOPA, e todas as melaninas apresentaram baixa toxicidade em células NIH-3T3 com uma relevante atividade antioxidante tendo destaque para a ser-DOPA que apresentou um EC50 para o ensaio de DPPH de 1,02 µg mL-1, valor esse próximo dos padrões utilizados.Os estudos de interação com os íons Cu(II) e Zn(II) revelaram que a formação dos complexos é altamente dependente do pH, em que na faixa ácida para a ser-DOPA e thr-DOPA ocorre a formação das espécies [M(QI)+] e [M(Ac)+], com o aumento do pH detectou-se a espécie [M(Cat)] e [M(QI)2], e em valores de pH acima de 8 as espécies [M(Cat)22-] e [M(QI)(Cat)-] foram detectadas. Já com a melanina cys-DOPA ocorre a formação das espécies [M(Tiol)+], [M(QI)+] e [M(QI)(Tiol)], com o aumento do pH foi evidenciado as espécies [M(Cat)] e [M(Cat)(Tiol)-], sendo esta última não detectada para Cu(II), e em valores de pH acima de 7 as espécies [M(QI)2] e [M(Cat)22-] foram observadas.Todos os complexos obtidos apresentaram uma baixa toxicidade em células HUVEC, e também uma relevante atividade antioxidante com destaque para o complexo cys-DOPA-Zn(II) com valor de 25,24 µg mL-1 para o ensaio de DPPH.As interações com o corante azul de metileno foram caracterizadas por métodos espectroscópicos, e os resultados obtidos revelaram que a adsorção do azul de metileno pelas melaninas é dependente do pH da solução. A maior adsorção ocorreu em pH 7 e 6 para a ser-DOPA e cys-DOPA respectivamente e a melanina thr-DOPA apresentou baixos valores de adsorção em toda faixa de pH. O modelo cinético que apresentou a melhor correlação entre os dados experimentais foi o de pseudo-segunda ordem para todos os sistemas estudados e os dados de equilíbrio de adsorção foram melhor correlacionados pela isoterma de Langmuir em sua forma linear apresentando qm de 162,07 e 109,89 mg g-1 para as melaninas cys-DOPA e ser-DOPA respectivamente.Abstract : Melanins are bio-oligomers occurring naturaly. They can be found in skin, hair, eyes, brain, and also in some marine animals, however, the extraction of natural melanins is not always feasible due to the high cost of the reagents used and the low yield in the process. In this context, synthetic melanins can be a praticle solution, which can be produced in the laboratory with a low cost and a high considerable yield.One of the synthetic melanins precursor is L-3,4-dihydroxyphenylalanine, known as L-DOPA that when free in reaction conditions produces eumelanin, responsible for the dark coloring, and in the presence of cysteine produces pheomelanin, which leads to a lighter color pigment, these products are aggregated in 3 to 9 indol units to form the oligomeric structure of melanin.In this context, this work aims to describe the preparation, purification and characterization of melanins chemically modified by the amino acids serine, threonine and cysteine (pheomelanins) resulting in compounds ser-DOPA, thr-DOPA and cys-DOPA respectively, and their complexes with Cu(II) and Zn(II) metal ions, evaluating their antioxidant activities and toxicities; as well as interactions with the cationic dye methylene blue.The spectroscopic characterization of the modified melanins showed the presence of three major groups: carboxylic acid, quinone-imine and catechol, and studies in solution by potentiometric titration showed the presence of thiol grouping cys-DOPA melanin, all melanins presented low toxicity in NIH-3T3 cells and a significant antioxidant activity with emphasis on ser-DOPA which showed an EC50 = 1.02 µg mL-1 for the DPPH assay, a value close to the standards used in this work.Interaction studies with Cu(II) and Zn(II) ions proved that the formation of complexes is highly pH dependent, where in the acidic range for ser-DOPA and thr-DOPA the species [M(QI)+] and [M(Ac)+] were formed, the increase of the pH leads to the formation of [M(Cat)] and [M(QI)2] species and pH above 8 the [M(Cat)22-] and [M(QI)(Cat)-] species were detected. On the other hand, in the cys-DOPA system at acidic pH the species [M(Tiol)+], [M(QI)+] and [M(QI)(Tiol)] were formed, with the increase of the pH the [M(Cat)] and [M(Cat)(Tiol)-] species were evidenced, the latter is undetected for Cu(II) system, and for pH above 7 the species [M(QI)2] e [M(Cat)22-] were observerd.All complexes showed low toxicity in HUVEC cells, and also showed a significant antioxidant activity, highlighting for the complex cys-DOPA-Zn(II) with a value of 25.24 µg mL-1 for the DPPH assay.The adsorption of methylene blue by melanins was characterized by spectroscopic methods, and the results showed that adsorption of methylene blue is dependent on the pH solution. The higher adsorption occurred in pH 7 and 6 for the ser-DOPA and cys-DOPA melanin respectively. Thr-DOPA showed low adsorption values independently of the pH. The kinetic model that showed the best correlation omong the experimental data was the pseudo-second order for all systems studied and the adsorption equilibrium data were best correlated with the linear Langmuir isotherm presenting qm values 162.07 and 109.89 mg g-1 for cys-DOPA melanin ser-DOPA respectively
Safety and tolerability of long-term apomorphine infusion in advanced Parkinson's disease: an Indian multi-center (APO-IND) experience
No full textAbstract Advanced Parkinson’s Disease (APD) is complicated by the emergence of motor and non-motor fluctuations, which are initially predictable and eventually become unpredictable, in part due to erratic gastric absorption and short half of oral levodopa. Attempts to manage such fluctuations with oral dopaminergic drugs often lead to disabling dyskinesias. Continuous Subcutaneous Apomorphine Infusion (CSAI), despite being approved for the treatment of APD since 1993, was approved in India only in 2019. We studied the safety, tolerability and efficacy of CSAI in Indian patients with APD in a registry design to raise local awareness of this important treatment. We conducted a prospective registry-based observational audit at 10 centers across different states of India. Patients with APD, not responding to or with significant side effects from oral dopaminergic therapy, were assessed at baseline and at month 6 and 12 following CSAI infusion. Fifty-one patients completed the study, CSAI significantly reduced the functional impact of dyskinesia (p < 0.01 at 6 months and p < 0.001 at 12 months). There was a significant improvement in the OFF-state from baseline (p < 0.01 at 6 months and p < 0.001 at 12 months) No discernible side effects were observed apart from mild site reaction (n = 7), nausea (n = 7) skin nodules (n = 2). CSAI demonstrated safety, efficacy, tolerability and improved quality of life in patients with APD, as shown in previous studies. Our study highlighted current existing inequalities in treatment availability, lack of awareness, knowledge gap, affordability and cost remains a concern regarding apomorphine use in Indian PD population
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