32 research outputs found
Jesus, moral regeneration and crime in the Gospel of John
Get PDFA structural and text-immanent approach to the Gospel of John reveals that Jesus of Nazareth came to earth to do the will of God his Father and to take away the sins of the world. The author/s makes/make it clear that Jesus taught Nicodemus that one needs to be born again in order to enter the kingdom of God. To be born again means that one must be born out of water and Spirit, that is, through becoming a follower or disciple of Jesus Christ, one’s life has to change. This change, also called regeneration, is, anthropologically-speaking, according to the rational-choice theory, a deliberate choice made by man to become a follower or disciple of Jesus and to do his Father’s will. The disciples are not called upon to be like robbers and thieves, focused on the accumulation of earthly wealth, but to love one another. Although Jesus was crucified because of an allegation of high treason, a crime against the state, He instructed his followers to forgive others and to remain in His love. In terms of the explicatio-applicatio model, the intended kerygmatic message of John to his intended readers is clear: he wants all people, including criminals, to believe in Jesus and to follow Him, because, according to the Johannine author/s, when one follows Jesus, one does not commit crime, because one has been morally regenerated.
Keywords: Jesus, moral regeneration, gospel of St John, crime, South Afric
Du paradoxe à l’unité : la construction médiatique d’une jeunesse catholique. La réception de la JMJ par des médias québécois francophones
Get PDFEn explorant la réception médiatique de la Journée Mondiale de la jeunesse qui s’est tenue en juillet 2002 à Toronto (Canada), l’auteur tente d’esquisser le portrait des jeunes et de leurs rapports à la religion catholique que la médiatisation de l’événement a permis de construire. L’analyse d’une série d’articles parus dans deux grands quotidiens québécois permet d’identifier différentes visions de la jeunesse mise en avant-scène par les médias. On y constate que l’insistance de départ sur l’hétérogénéité de la jeunesse fait rapidement place à la présentation d’une jeunesse catholique homogène et unie autour de Jean-Paul II. Or, un tel rapport des jeunes au catholicisme va à l’encontre des principales conclusions de la recherche sur cette question. À cette réception de la JMJ par des médias québécois sont proposées certaines pistes d’explication concernant notamment le statut, le rôle et le fonctionnement des médias de masse dans nos sociétés.While examining the reception given by the media to the World Youth Day held in July 2002 in Toronto (Canada) as well as their promotion of the event, the author tries to draw the profile of the youth, and its links with catholic religion. The analysis of press articles published into two important Quebec daily newspapers allows the identification of different visions of the youth put forward by the media. It can be noticed that the emphasis put on youth heterogeneity at the beginning quickly moves to the presentation of a homogeneous youth united around Pope John-Paul II. However, such a relation of youth toward Catholicism goes against research major conclusions on this topic. To this reception of the WYD by Quebec media, several explanations about, among others, mass media status, role, and functioning in our society are proposed
Approximation Schemes For Maximum Cardinality Matching
No full textLet G = (V ; E) be an undirected graph. Given an odd number k = 2l + 1, a matching M is said to be k-optimal if it does not admit an augmenting path of length less than or equal to k. We prove jMj jM j(l+ 1)=(l+ 2), where M is a maximum cardinality matching. If M is not already (k + 2)-optimal, using M, in O(jEj) time we compute a (k + 2)-optimal matching. We show that starting with any matching, repeated k-optimizations result in an optimal matching in O( p jM jjEj) time. This approximation scheme extends to the minimum weight perfect matching, and the minimum weight uncapacitated perfect 2-matching problems over complete graphs, and complete bipartite graphs with edge weights of one and two. In particular, we obtain a fast approximation algorithm for the traveling salesman problem over complete graphs with edge weights of one and two.Technical report lcsr-TR-24
The Effect Of Learning Stress In The Faculty Of Medicine On The Arising Of Acne Vulgaris In Students Of The Faculty Of Medicine YARSI University And Its Review From The Islamic View
Get PDFStress is an emotional mental disorder that a person faces because of pressure. Stress is an emotional mental disorder that a person faces because of pressure. Psychosocial stressors can cause physical pain, such as headaches, dizziness, pimples, and so on. The purpose of this research is knowing the effect of stress studying at the Faculty of Medicine with the emergence of acne vulgaris in students of the Faculty of Medicine, YARSI University. The type of research that will be used in this study is the observational analytic method. The population in this study were students of class 2020 and 2021 at the Faculty of Medicine, YARSI University. Determination of the sample to be carried out is by simple random sampling. This study used univariate and bivariate analysis methods. Univariate analysis to describe the characteristics of respondents, the incidence of learning stress and acne vulgaris. The results showed that respondents who experienced academic stress based on the Scale for Assessing Academic Stress questionnaire were 62 students (39.5%). Respondents who suffered from acne vulgaris based on the Global Acne Grading System questionnaire were 133 students in the mild category and 5 students in the moderate category. The results of this study indicate that there is no relationship between stress and the incidence of acne vulgaris in Yasri University Medical Faculty Students Class of 2020-2021. In Islam, everyone will not escape from being given trials by Allah SWT. So in facing trials a Muslim needs to have patience and always think positively
Bibliometric analysis of genetic variations in schizophrenia
Get PDFSchizophrenia is a complex neuropsychiatric disorder with significant genetic variation as an aetiology. This study aimed to explore genetic variation-related research in schizophrenia from a bibliometric perspective. A systematic search was conducted using the Scopus database to identify literature related to schizophrenia and genetic variation published between 2014 and December 17, 2023. The bibliometric data were analyzed using software such as biblioMagika®, Biblioshiny, and VOSviewer. A total of 344 publications were retrieved, showing a growth in the number of publications and citations over time, with the United States (US) having the highest number of publications at 121. Analysis of co-authorship by country also highlighted the US as the leading contributor. Michael Conlon O’Donovan was recognized as the most dominant author in the field. The Schizophrenia Research journal was found to be the most productive. Keyword analysis across different clusters identified significant research directions in schizophrenia, emphasizing treatment efficacy and the interaction of genetic and environmental factors. These findings provide a comprehensive perspective on the broader landscape of this research topi
Automated Detection of Retinal Diseases Using Artificial Intelligence-Enhanced Ocular Coherence Tomography Imaging: Bibliometric Analysis
Get PDFArtificial intelligence (AI) has revolutionized optical coherence tomography (OCT) imaging for the better detection of retinal diseases like diabetic retinopathy (DR), age-related macular degeneration (AMD), and glaucoma. Here, bibliometric analysis of AI in OCT is presented. We conducted a systematic search in the Web of Science Core Collection (WoSCC) database up to January 22, 2025 with the help of AI and OCT-related terms. The journal articles and reviews on the topic were examined based on publication trends, author productivity, institution affiliation, and keyword co-occurrence. Visualization was performed through VOSviewer software (1.6.20). A total of 765 articles were analyzed with an increasing trend in publications, led by the USA (30.7%), China (23.3%), and the UK (11.1%) in research production. The most cited institution was the Medical University of Vienna (9.0%), and the most productive journal was Scientific Reports (7.3%). The most common keywords were "Optical Coherence Tomography", "Deep Learning", and "Diabetic Retinopathy" with frequency of 469, 297, 221, respectively. Our review of AI-enhanced OCT for retinal diseases was both comprehensive and systematic, identifying key trends and current research hotspots. As research productivity in this field continues to grow, the focus is increasingly shifting toward developing more accurate AI-driven imaging techniques to improve the diagnosis of various retinal diseases. Future work should prioritize algorithm validation and clinical implementation to facilitate widespread adoptio
Hubungan antara Pengaturan Pola Makan dan Akupunktur pada Penurunan Berat Badan
Get PDFPENGARUH PENGATURAN MAKAN DAN AKUPUNKTUR PADA PENURUNAN BERAT BADAN Nur Asiah1, Tuty Herawaty2, Sri Hastuti Andayani3Departemen Gizi Fakultas Kedokteran Universitas YARSI Departemen Anak Fakultas Kedokteran YARSIDepartemen Anak Fakultas Kedokteran [email protected] Author: [email protected] BelakangTerdapat beberapa cara menurunkan berat badan, salah satunya pengaturan pola makan. Pengaturan pola makan meningkatkan kesadaran pasien akan pentingnya diet. Selain itu terdapat metode akupunktur yang aman dan murah. Penggunaan kedua metode bersamaan diharapkan lebih efektif dalam penurunan berat badan untuk mencegah komplikasi obesitas.TujuanPenelitian bertujuan untuk mengetahui penurunan berat badan pada wanita obes dengan metode diet dan akupunkturMetodologi Penelitian%Penelitian menggunakan metode kuasi eksperiment dengan mengukur berat badan sebelum diet dan akupunktur dan setelahnya selama 6 minggu terhadap 13 orang perempuan obes (Indeks Massa Tubuh 27-36 kg/m2), 29-54 tahun di Rumah Sakit Pasar Rebo Jakarta pada tahun 2010. Diet berupa 25 kkal/kg berat badan (600-800 kalori defisit dari kebutuhan). Akupunktur sekali seminggu pada perut dan kaki. Diet dengan komposisi 55% karbohidrat, 15% protein dan 25% lemak. Pengaturan makan meliputi jumlah, jenis, frekuensi dan cara memasak dengan panduan formulir, daftar makanan dan model replika makanan.Hasil PenelitianTerdapat penurunan berat badan sebesar 2,8 ±0,7 kg secara tidak bermakna setelah pemberian diet dan akupunktur selama 6 minggu pada perempuan obes dan penurunan indeks massa tubuh sebesar 1,08 ± 0,90 kg/m2.DiskusiDiet dan akupuntur dapat menurunkan berat badan wanita obes. Akupunktur tidak akan memberikan hasil optimal dalam penurunan berat badan tanpa pengaturan pola amkan yang baik.Kata Kunci: Pengaturan Makan, Akupunktur, Obes
Editorial: Antimicrobial Resistance (AMR): Challenges and Opportunities, A Special Issue of the Jordan Medical Journal
Get PDFA Brief View of the Global Situation of Antimicrobial Resistance (AMR)
Antimicrobial resistance (AMR) is undermining the effectiveness of life-saving treatments and placing populations at heightened risk, whether from common infections or even routine medical interventions [1]. In 2014, the “Review on AMR” projected that 10 million deaths caused by AMR could occur by 2050. This helped position AMR as one of the most pressing threats to health of the 21st century [2].
With the antimicrobial increasing use and misuse, microorganisms have developed AMR. The phenomenon of AMR refers to the potential of microorganisms including bacteria, viruses, fungi, and parasites to continue to grow in the midst of drugs designed to kill them [3]. Infections caused by antimicrobial-resistant organisms are not only difficult to treat, there is also an increased chance of severe illness and even death due to these infections [3].
AMR is an evolutionary phenomenon shown by all organisms through development of mutations in order to withstand the lethal environmental selection pressure which subsequently, makes these drugs ineffective. Thus, with the ever-increasing use of antibiotics in healthcare and agriculture, bacteria had huge opportunity to develop AMR [3].
As a response to this crisis, the May 2015 World Health Assembly adopted a global action plan on AMR, which outlines five objectives: 1) to improve awareness and understanding of AMR through effective communication, education and training; 2) to strengthen the knowledge through surveillance and research; 3) to reduce the incidence of infection through hygiene and infection prevention measures; 4) to optimize the use of antimicrobials in human and animal health; and 5) to increase investment in new medicines, diagnostic tools, vaccines and other interventions [4].
However, despite these calls and alarms, the current situation is still alarming. The findings of the recent “Global antibiotic resistance surveillance report 2025” are concerning. It showed the global resistance is extensive with wide regional variations, an increasing threat from Gram negative bacterial pathogens, higher levels of AMR are reported from settings with low AMR surveillance coverage report, and that AMR is disproportionately affecting low and middle income countries [1].
More specifically, the report highlights the following findings: one in six laboratories confirmed infections worldwide were caused by AMR bacteria, resistance was most common in urinary tract infections (1 in 3 infections), blood stream infections (1 in 6), and in gastrointestinal (1 in 15). Resistance was most common in South East Asia and Eastern Mediterranean regions (1 in 3), followed by the African region (1 in 5). Resistance was less frequent in the European region (1 in 10), and least frequent in the Western Pacific region (1 in 11) indicating wide regional disparity [1]. The report also indicates that AMR has increased by 40% between 2018 and 2023. In particular, resistance to carbapenems and fluoroquinolones is increasing among Gram negative pathogens including Acinetobacter spp, Escherichia coli, and Klebsiella pneumoniae. This is a concern as these antibiotics are used to treat severe and life-threatening infections [1].
One important and key strategy for addressing the AMR crisis has been the development of new antibiotics. However, antibiotic development has had several scientific and economic challenges over the years [5]. The WHO reports that only 13 new antibacterial agents have been developed since 2017, with only 2 representing a new chemical class. Overall, the timeframe required for developing these drugs and conducting clinical trials, the likelihood of failure, and the lack of innovation threaten the future of clinical interventions [6].
AMR also has economic implications and is globally draining resources from economies, including the health-care, agriculture, and food production sectors [7]. AMR might reduce the world’s gross domestic product (GDP) by 1.1% and its cost may exceed US$ one trillion annually after 2030 across the globe [8].
At present, the proposed approaches to mitigate global AMR crisis include: antibiotic stewardship, development of new antibiotics, combination therapy, phage therapy, probiotics and prebiotics, immunotherapy, repurposing existing drugs, alternative to antibiotics, education and public awareness, surveillance systems, environmental regulations, and one health approach [9].
In conclusion, AMR is a serious global threat that threatens treatment of infections and decades of medical progress. Urgent, coordinated global action is needed to preserve the effectiveness of antimicrobials for the future
Antimicrobial Resistance in Jordan: A Critical Moment for National Action
Jordan, like many countries in the region, is witnessing a steep rise in AMR [10,11]. National surveillance data demonstrate particularly alarming levels of resistance: Acinetobacter spp. exhibit carbapenem resistance exceeding 80%, Staphylococcus aureus continues to show high methicillin resistance rates, and extended-spectrum β-lactamase (ESBL) production is widespread among Enterobacterales. Community-acquired pathogens—including E. coli—demonstrate rising resistance to commonly used oral therapies, signaling diminishing effectiveness of first-line treatments and highlighting the urgent need for coordinated stewardship interventions [10-12].
Clinical and Public Health Significance
The clinical impact of these resistance patterns is profound. AMR prolongs illness, increases mortality risk, and substantially elevates healthcare costs. It compromises the safety of routine medical procedures, from surgical interventions to hematologic treatments, and limits therapeutic options for common infections [13]. At the community level, non-prescription antibiotic access, cultural expectations surrounding antibiotics, and misconceptions about viral illnesses continue to drive unnecessary consumption [14]. In this context, AMR has become both a medical and societal challenge, demanding a comprehensive response that integrates clinical stewardship, regulatory reinforcement, and public engagement.
The Role of Youth and Community Awareness
Amid rising resistance, Jordan has a unique opportunity to mobilize a new generation of healthcare professionals and community leaders. Youth—particularly university students in medicine, pharmacy, and allied health fields—hold considerable influence within families, academic institutions, and digital platforms, enabling them to serve as catalysts for behaviour change. Emerging national initiatives, such as youth-led AMR advocacy networks, social media campaigns, and peer-driven educational programs, demonstrate the effectiveness of combining scientific messaging with culturally resonant communication strategies [15,16]. These initiatives help bridge the gap between clinical practice and public expectations, particularly through mechanisms such as hospital-based AMR counselling committees that offer clear explanations to patients when antibiotics are not indicated.
Towards a Nationally Integrated Response
A sustainable national response to AMR requires multisectoral collaboration across academic institutions, healthcare providers, ministries, and community stakeholders. Strengthening stewardship programs, embedding AMR education within university curricula, improving transparency around prescribing decisions, and expanding community engagement efforts are essential pillars of this approach [17]. Integrating surveillance findings with awareness campaigns ensures that resistance data do not remain isolated within laboratories or policy documents, but instead inform public behaviour and clinical practice.
Purpose of this Special Issue
The Jordan Medical Journal (JMJ) has recently announced a call for a special issue titled “Antimicrobial Resistance (AMR): Challenges and Opportunities” for 2025. The purpose of this special issue is to present current national surveillance findings, expert reviews, clinical perspectives, and community-based models relevant to AMR in Jordan thereby elevating AMR as a shared national responsibility. The collection aims to highlight both the scientific realities revealed through surveillance and the societal dimensions of awareness, behaviour, and stewardship. This issue also seeks to support a unified national strategy that preserves antimicrobial effectiveness and strengthens Jordan’s resilience against the growing threat of resistance through interdisciplinary dialogue and evidence-based recommendations.
Contents covered by the special issue on AMR
A considerable number of manuscripts were received from researchers worldwide in response to the call for the special issue. Following a rigorous selection process by the Editor-in-Chief and Associate Editors, as well as a thorough anonymous peer review, nine articles were accepted for publication. This special issue features original research and review articles from highly recognized experts, covering AMR governance, epidemiological trends, resistance and virulence genes, public awareness, infection prevention and control, antibiotic stewardship, and the One Health approach.
Carbapenem-resistant Acinetobacter baumannii (CRAB) is among the most challenging bacterial pathogens and has become widely distributed throughout the Mediterranean region [18]. In Jordan, numerous reports have highlighted the increasing prevalence, impact, and severity of CRAB infections [18,19]. In this context, a study by Zueter et al., published in this special issue, demonstrated an increased prevalence of several virulence genes—specifically bap, OmpA, surA, PLD, paaE, and basD—alongside a high capacity for biofilm formation in clinical CRAB isolates from Jordan. These findings suggest mechanisms for the enhanced survival of CRAB in hospital environments and its significant resistance to treatment [20].
In the same vein, Kuruva et al., from India in their review on tracking A. baumannii in critical care, discuss the pathogen's behavior and spread, as well as the utility of quantitative PCR and whole-genome sequencing for rapid detection. The review also outlines various hospital control measures, emphasizing the importance of environmental monitoring and a One Health approach to combat AMR. Furthermore, the authors propose future research directions, including metagenomic surveillance, machine learning and modeling, and pangenome-guided drug discovery [21].
The increased prevalence of hospital-acquired infections, particularly in intensive care units (ICUs), remains a critical challenge in the fight against AMR. Analysis of bacterial isolates collected from 12 ICUs across Jordan revealed that 41.2% were multidrug-resistant (MDR), 17.5% were extensively drug-resistant (XDR), and 6.8% were pandrug-resistant (PDR). MDR rates were highest among Klebsiella (82%) and Acinetobacter (79%) species. Furthermore, the study identified key resistance genes, including blaKPC in K. pneumoniae, mecA in Staphylococci, blaCTX-M in E. coli, blaOXA-51 and blaOXA-23 in A. baumannii, and the vanA gene in E. faecalis [22].
A three-year retrospective study examining common isolates and the sensitivity patterns of blood cultures from pediatric cancer patients in Libya indicated that Gram-positive organisms were the most frequently isolated bacteria (58.2%), with S. aureus being the most prevalent. Pseudomonas aeruginosa and Klebsiella pneumoniae were the most common Gram-negative isolates; notably, a higher proportion of carbapenem resistance was observed in K. pneumoniae [23].
The antibiotic susceptibility and resistance genes of E. coli isolates collected from two tertiary centers in Jordan revealed that 57.8% of samples were resistant to cefoxitin, a resistance mostly mediated by the CMY-2 gene. Additionally, 38% were resistant to gentamicin, with 61.4% harboring the aac(6’)-Ib-cr gene, while 65.7% of isolates were resistant to ciprofloxacin—nearly all of which were positive for the gyrA gene. Notably, only 2% of isolates showed resistance to imipenem and meropenem. These findings are instrumental in guiding appropriate antibiotic therapy and combating the spread of resistant E. coli in Jordan [24]. Other previous studies investigating ESBLs rates and resistance genes in Jordan have similarly identified CTX-M as the most prevalent genotype [12,25,26].
An interventional randomized controlled study involving 132 hospitalized pediatric patients in Jordan identified administration errors as the most frequent antibiotic-related problem. These errors were reduced by 70.67% in the intervention group; furthermore, the incidence of side effects stemming from inappropriate antibiotic use was significantly lowered, alongside a reduction in the average length of hospital stay. The study concludes that clinical pharmacist interventions significantly enhance the appropriate use of antibiotics in pediatric settings [27].
Taha et al., study utilizing structured questionnaires among 238 Jordanian women of reproductive age revealed a 25.7% prevalence rate of antibiotic misuse. The findings showed weak associations between misuse and factors such as higher family income or larger family size, while a higher level of education was found to slightly decrease the likelihood of obtaining antibiotics without a prescription. Such misuse is a primary driver that facilitates the development of antibiotic resistance [28]. These findings are supported by a systematic review of antibiotic misuse in Jordan, which indicated a high prevalence rate of inappropriate use, particularly among children with upper respiratory tract infections [29].
A cross-sectional study utilizing the WHO multi-country public awareness questionnaire to assess AMR awareness in Jordan revealed that 85.1% of participants were unable to define antibiotic resistance correctly. Furthermore, 45.6% mistakenly believed that the common cold could be treated with antibiotics [30]. These findings align with a previous study indicating that 39% of medical university students incorrectly identified bacteria as the cause of the common cold. Such data underscores the urgent need for targeted public education campaigns to enhance awareness and rectify these persistent misconceptions [31].
Finally, Shedeed describes the factors contributing to the poor implementation of antibiotic stewardship by employing multi-level and polycentric governance theory. The review, extracted in part from the author's master’s thesis, maps and analyzes the key actors, institutional arrangements, and policy mechanisms that shape stewardship efforts. The author notes that stewardship governance remains fragmented, underfunded, and poorly implemented in low- and middle-income countries. To address these gaps, they propose an original Integrated Polycentric Glocal Governance Framework (IPGF), applying it to two case studies within the Middle East and North Africa (MENA) region to strengthen global antibiotic stewardship and mitigate the AMR crisis [32].
In conclusion, this Special Issue highlights the multifaceted nature of the AMR crisis. The featured research underscores a critical escalation in AMR of A. baumannii, E. coli, and K. pneumoniae—driven by complex genetic mechanisms and widespread clinical prevalence. The articles identify significant systemic gaps, including low public awareness, frequent antibiotic misuse, and fragmented governance. Mitigating AMR requires a unified, One Health approach that integrates clinical precision, public education, and policy reform
A memory model for internet hits after media exposure
No full textWe present a cognitive model, based on the mathematical theory of point processes, which extends the results of two studies by Johansen (Physica A 276 (2000) 338; Physica A 296 (2001) 539) on download relaxation dynamics. Responses from subjects are considered as single events, which are received from original listeners or readers and from a network of social contacts, through which a message may propagate further. We collected data on the number of daily visits at our web site after a radio interview with the second author, in which the name of the web site was mentioned. A model based on an exponential hit time distribution and a homogeneous point process for regular visitors fits our data and Johansen's very well and is superior to both the power law and the logarithmic function. The fits suggest that hit data from different sources share the same cognitive mechanism, which are controlled merely by the encoding and retrieval of the target information memorised. (C) 2003 Elsevier B.V. All rights reserved
