2,617 research outputs found

    Toward ELF Magnetic Fields for the Treatment of Cancer

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    The possibility of a link between childhood leukemia and other cancers and extremely low-frequency magnetic fields has given rise to several epidemiological studies. The existence of amplitude and frequency windows prompts the need of screening through the different parameters of exposure for two reasons: optimization and avoidance of undesired effects. In principle, the most purist, safest way of going from experiments with cellular cultures to experiments with small animals and then finally to clinical trials with humans would be to use homogeneous fields in these several stages. In this way, dosimetry would be much easier, but the drawback would be substantial: for the treatment of humans, much bigger facilities should be used, in order to house devices big enough to generate homogeneous fields in a volume equal to or greater than a human being.Fil: Makinistian, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich". Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich"; ArgentinaFil: Belyaev, Igor. Slovak Academy of Sciences; Eslovaqui

    Magnetic Maps Raw Data

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    The file contains a folder with all the raw data from magnetic maps of figures 2, 3 and 4 of our article: L. Makinistian, I. Belyaev. 2018. Magnetic field inhomogeneities due to CO2 incubators shelves: A source of experimental confounding and variability? Royal Society Open Science

    Effect of Intermittent ELF MF on Umbilical Cord Blood Lymphocytes

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    Having recently shown that intermittent extremely low frequency (ELF) magnetic fields (MF) inhibited proliferation of a cancer cell line, we wondered whether such fields could have some effect on normal blood cells. In order to test this, we exposed umbilical cord blood lymphocytes (UCBL) to MF with the same waveform (triangular, 7.8 Hz) and intermittence (250 s ON / 250 s OFF) during 48 h and 72 h, testing six amplitudes (between 6 µT and 24 µT) simultaneously in each experiment. We assessed percentages of viable, early apoptotic (EA) and late apoptotic/necrotic (LAN) cells, reactive oxygen species (ROS) production, and DNA double strand breaks (DSB) indicated by formation of 53BP1 and gamma-H2AX foci and their co-localization. No effect on DSB or ROS production was found for either exposure duration. However, a statistically significant decrease in viability occurred for field amplitudes below 17 µT after the 72-h exposure. It is remarkable that the effect appeared for field intensities below a certain threshold, strongly suggesting an amplitude window and thus the need of screening for different amplitudes of the same MF waveform.Fil: Zastko, Lucián. Slovak Academy of Sciences; Eslovaquia. Comenius University of Bratislava; EslovaquiaFil: Makinistian, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich". Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto de Física Aplicada "Dr. Jorge Andrés Zgrablich"; ArgentinaFil: Moravčíková, Andrea. Slovak Academy of Sciences; EslovaquiaFil: Jakuš, Ján. Comenius University of Bratislava; EslovaquiaFil: Belyaev, Igor. Slovak Academy of Sciences; Eslovaqui

    To the centenary of the birth of outstanding evolutionist Dmitri Konstantinovich Belyaev

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    This paper is a tribute to outstanding evolutionary biologist Dmitri Konstantinovich Belyaev in connection with the forthcoming centenary of his birth. His work on variation-related mechanisms in animal domestication made this process much faster. Belyaev is at length described as a person, as a scientist and as the organizer of the Institute of Cytology and Genetics of the Siberian Branch of the USSR Academy of Sciences. The author had for many years worked as Belyaev’s Deputy for Science, and, when Dmitri Konstantinovich passed away, had for 22 years headed the Institute of Cytology and Genetics. Belyaev’s life was not easy: he was a priest’s son and an “enemy of the people”’s brother. He was in the battlefield all through the Great Patriotic War and became a man of steel. His struggle for the restoration of genetics in the country, his commitment to setting up and maintaining relationships between masters and followers and many more other aspects of his life are considered. The global importance of the “master – follower” paradigm as a basis of the continuity of generations is underlined and re-underlined, for this is a very special point in the scientific community, especially when new schools of science emerge

    Observation of J/ψ-pair production in pp collisions at √s=7 TeV

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    The production of J/ψ pairs in proton–proton collisions at a centre-of-mass energy of 7 TeV has been observed using an integrated luminosity of 37.5 pb−1 collected with the LHCb detector. The production cross-section for pairs with both J/ψ in the rapidity range 2 < yJ/ψ < 4.5 and transverse momentum pJ/ψ T <10 GeV/c is σJ/ψJ/ψ =5.1±1.0±1.1 nb, where the first uncertainty is statistical and the second systematic

    Bishop Apollos (Belyaev) and Development of Vyatka Diocese in 1866—1885

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    Using mainly historical-comparative and historical-genetic methods, the issue of the development of the Vyatka and Slobodsk dioceses, which coincides within the borders with the Vyatka province, under Bishop Apollos (Belyaev), is considered in the article. The author pays special attention to the process of organizing religious, educational and missionary activities, and up to the appointment of Bishop Apollos, the results of this work were insignificant. The novelty of the research lies in the fact that for the first time it comprehensively examines the activities of the Vyatka Bishop Apollos in terms of the implementation of a nationwide religious course, which included active educational and missionary work of the local clergy. Under Bishop Apollos, to increase the influence of the clergy on the local population, including the Old Believers and non-Orthodox, important transformations were carried out: a separate vicariate was allocated in the diocese, the Vyatka Committee of the Orthodox Missionary Society and the Vyatka Brotherhood of St. Nicholas the Wonderworker were opened, and the work of the local clergy was also generally reorganized. This gave the first positive results in strengthening the position of the Russian Orthodox Church among the local population of the Vyatka diocese

    No repulsion between critical points for planar Gaussian random fields

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    We study the behaviour of the point process of critical points of isotropic stationary Gaussian fields. We compute the main term in the asymptotic expansion of the two-point correlation function near the diagonal. Our main result implies that for a ‘generic’ field the critical points neither repel nor attract each other. Our analysis also allows to study how the short-range behaviour of critical points depends on their index

    Measurement of the effective B0s→K+K− lifetime

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    A measurement of the effective lifetime is presented using approximately 37 pb−1 of data collected by LHCb during 2010. This quantity can be used to put constraints on contributions from processes beyond the Standard Model in the meson system and is determined by two complementary approaches as τKK=1.440±0.096 (stat)±0.008 (syst)±0.003 (model) ps

    Towards model-independent approach to the analysis of interference effects in pair production of new heavy quarks

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    We propose a model independent approach for the analysis of interference effects in the process of QCD pair production of new heavy quarks of different species that decay into Standard Model particles, including decays via flavour changing neutral currents. By adopting as ansatz a simple analytical formula we show that one can accurately describe the interference between two different such particle pairs leading to the same final state using information about masses, total widths and couplings. A study of the effects on differential distributions is also performed showing that, when interference plays a relevant role, the distributions of the full process can be obtained by a simple rescaling of the distributions of either quark contributing to the interference term. We also present the range of validity of the analytical expression that we have found. © 2014 The Author(s)
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