2,410 research outputs found
Telosticta fugispinosa sp. nov. from Sabah (Odonata: Zygoptera: Platystictidae)
No full textDow, Rory A., Afendy, Aqilah, Rahman, Homathevi (2016): Telosticta fugispinosa sp. nov. from Sabah (Odonata: Zygoptera: Platystictidae). Zootaxa 4103 (4): 390-395, DOI: 10.11646/zootaxa.4103.4.
Telosticta fugispinosa Dow, Afendy & Rahman, 2016, sp. nov.
No full textTelosticta fugispinosa sp. nov. (Figs. 1–12) Telosticta undetermined D;— Dow & Orr (2012: 396, record of female, Poring Hot Springs, Sabah). Type material: Holotype: 1 ♂ (SAB 12 _PST 1, RMNH.INS. 507772), Malaysia, Sabah, West Coast Division, Crocker Range National Park, Inobong, Kimamabang waterfall stream system (below waterfall), 21 ix 2012, leg. R. A. Dow, in RMNH. Paratypes: All from Malaysia, Sabah, West Coast Division: 3 ♂ (SAB 12 _PST 49; SAB 12 _PST 72, RMNH.INS. 507677; SAB 12 _PST 77, RMNH.INS. 507668), Kinabalu National Park, Poring Hot Springs, small streams crossed by or near to trail to Langanan waterfall, above Kipungit stream, 11 ix 2012, leg. R.A. Dow; 1 ♂ (SAB 12 _PST 48), same location and collector, 12 ix 2012; 1 ♀, same area, trailside in forest, 21 iv 2005, leg. unknown, in RMNH; 10 ♂ (SAB 12 _PST 3, RMNH.INS. 507747; SAB 12 _PST 32–37; SAB 12 _PST 62, RMNH.INS. 597748; SAB 12 _PST 66, RMNH.INS. 507755), 1 ♀ (SAB 12 _PST 4; RMNH.INS. 507749), location as holotype, 18 ix 2012, leg. R.A. Dow; 4 ♂ (SAB 12 _PST 29 –31, 87), same location and collector, 19 ix 2012; 6 ♂ (SAB 126 _PST 6 –9, 26; SAB 12 _PST 61, RMNH.INS. 507770), 1 ♀ (SAB 12 _PST 27, in tandem with SAB 12 _PST 26), data as holotype; 3 ♂ (AA044, 49, 57; ODO 01378 - 80), same location, 22 ix 2012, leg. A. Afendy, in ITCB; 1 ♂ (SAB 12 _PST 84, RMNH.INS. 507766), same national park, Inobong, Batu Dinding stream system, 20 ix 2012, leg. R.A. Dow. Etymology. fugispinosa, an adjective suggesting a fleeting spine, in reference to the absent or vestigial spine on the paraprocts. Description of holotype male. Head: Labium pale. Basal 2 / 3 of labrum pale blue, black along free margin. Anteclypeus blue, postclypeus shining black. Mandible bases blue in corner by clypeus, black below. Vertex and frons bronzy black, occiput shining black. Ratio of width of compound eye to width of vertex measured at level of lateral ocelli slightly more than 9 / 10. Transverse occipital carina with lateral extremities angulated and prominent. Ocelli whitish. Antenna with scape and pedicel pale yellowish, brown at top of pedicel, remainder missing. Thorax: Prothorax whitish with blue tint to central parts anterior and middle pronotal lobes, except to rear of propleuron where there are irregular dark markings; small black central marking on anterior pronotal lobe, irregular black markings to rear of middle pronotal lobe; entire posterior lobe black, becoming grey apically on long lateral process (Fig. 3) with tip reaching level of lower margin of propleuron. Synthorax: Mesepisternum bronzy black, with pair of blue antehumeral stripes extending ca two-thirds of distance to wing bases (Fig. 5). Antealar triangles pale blue along mid-dorsal carina and in half at wing bases, rest black. Mesepimeron black. Metepisternum largely occupied by pale band, becoming blue towards wing bases, with short brown triangle based at antealar carina below, this extended as brownish band along metapleural suture to level of spiracle (Fig. 6). Metepimeron almost entirely pale. Venter of synthorax pale. Legs (only right anterior and right middle legs still present beyond trochanter, left posterior leg entirely missing, however all legs agreeing with the description below in paratypes): each with coxa and trochanter pale, femur and tibia pale except around joint and black stripe along extensor surface of femur. Tarsus pale with some darker areas, very dark brown at apex and brown claws. Wings: 13 (left) to 14 (right) Px in Fw, 12 (left) to 13 (right) Px in Hw. Vein ab absent. Arculus slightly distal to Ax 2. R 4 arising distal to subnodus, IR 3 joined to it by short stalk. Pterostigma trapezoidal with costal side slightly shorter than anal side, very dark brown with narrow white border, covering slightly more than one underlying cell. Abdomen: Largely dark brown and black. S 1 pale with narrow darker apical annulus. S 2 with yellowish cream basal annulus, divided dorsally, laterally this extending to posterior carina as pale wedge, otherwise dark brown. S 3–7 dark brown with narrow pale basal annulus, faint centrally dorsally. S 8 black with pale band along lower margin joined to large blue lateral dorsal marking, narrowly and irregularly divided dorsally (Fig. 7). S 9–10 black. Anal appendages (Figs. 10–12) largely black, with pale areas interior apically on cerci and scoop of paraprocts pale, also ventrally at interior base of paraprocts. Cerci ca 2.5 times length of S 10, interior projection well developed as spur at ca one-third length from base, directed first inwards then expanded slightly upwards and strongly downwards directed, spur clearly visible in dorsal (Fig. 10) and lateral (Fig. 11) view, with peg-like appearance in lateral view. Dorsal projection weakly developed, visible in dorsal view as small bump (Fig. 10). Cerci expanded dorsoventrally and interiorly shortly after half length, lower margin irregular, small subapical cleft (Fig. 11). Paraprocts just shorter than cerci, scoop spoon-like, turned inwards (Figs. 12), spine vestigial, not easily visible. Genital ligula of typical form for genus, with tongue-like structure of terminal segment long. Measurements (mm): abdomen without anal appendages 38.5, cercus just over 1, Hw 20.5. Description of paratype female (SAB 12 _PST 27). As male except as noted. Thorax: Posterior pronotal lobe with only short lateral processes (Fig. 4). Wings: 14 Px in Fw, 13 Px in Hw. Abdomen: S 3–5 with pale basal annulus not faded dorsally. S 6 with no basal annulus but small white basal dorsal mark present. S 7 with complete broad white basal annulus. Blue mark covering much of dorsum of 8 (Fig. 9). S 10 short. Cerci just shorter than S 10, approximately triangular. Ovipositor extending just beyond cerci, mostly black and dark brown with obscure pale markings. Measurements (mm): abdomen without appendages or ovipositor 33, Hw 21. Variation in paratypes. The black marks on the anterior pronotal lobe and the rear part of the middle pronotal lobes are variable in size, almost entirely absent in a few individuals and more extensive in others; occasionally the anterior lobe marking is joined to those on the rear of the posterior pronotal lobe via the central pit. The shape of the blue dorsal marking on S 8 of the male paratypes is variable, and the marking is frequently not divided centrally (e.g., Fig. 8); this is the case in all individuals from Poring. The spine of the paraprocts is entirely absent in some males. In males the only other significant variation is in size, with all individuals from Poring at the upper end of size range given below. In the two other female paratypes there is a basal pale annulus on S 6. Measurements (mm): Males: abdomen without anal appendages 36–46, Hw 19–24.5, 12–14 Px in Fw, 11–13 Px in Hw. Females: abdomen without anal appendages or ovipositor 34–37, Hw 21.5 –24, 13– 14 Px in Fw, 12–13 Px in Hw. Diagnosis. A small Telosticta with long blue antehumeral stripes. Males are easily distinguished from all other species of Telosticta by the form of the paraprocts, with the scoop turned sharply inwards and with a vestigial or no spine; the shape of the terminal half of the cerci is also distinctive, and dorsal blue markings on the terminal abdominal segments are confined to S 8. Remarks. Individuals of both sexes were found at moderate- to high-gradient forest streams from approximately 500–800m above sea level. In Fig. 6 there appears to be a small pale mark on the mesopleural suture near antealar carina of the holotype, this is actually an artefact in the image and does not really exist. The female reported as ‘ Telosticta undetermined D’ from Poring Hot Springs in Dow & Orr (2012: 396) and listed as a paratype here, along with the other female not collected in tandem with a male, are considered to belong to T. fugispinosa, as males were found in the same area and no other species of Telosticta has been found at Poring. However, in general the female may prove difficult to separate from those of other species of Telosticta with similar-length antehumeral markings; the female of the only other species known to occur in Sabah, T. janeus Dow & Orr, 2012, is not yet known. The known distributions of T. fugispinosa and T. janeus are allopatric, with the former known from Mount Kinabalu and the Crocker range and the latter from the south and east of Sabah, with published records from the Danum Valley and Imbak Canyon (Dow & Orr 2012: 394). The identity of ‘ Telosticta undetermined C’, reported from the Silau Silau stream near to the Kinabalu National Park headquarters (Dow & Orr 2012: 396; a large-sized teneral male) remains open, but it is likely to represent a third species of Telosticta from Sabah. Of the provisional species groups defined in Dow & Orr (2012), T. fugispinosa fits best into the feronia -group. Using the key in Dow & Orr (2012), exactly as in the case of T. iban Dow, 2014 (Dow 2014: 78), T. fugispinosa would key out as T. dayak Dow & Orr, 2012, or break the key, depending on how liberally couplet 7 was interpreted. The key could most easily be modified to accommodate T. fugispinosa by introducing a new couplet 6 distinguishing between species with the scoop of the paraproct sharply inturned, with vestigial spine (e.g., T. fugispinosa) from all others. No other species included in Telosticta has the spine on the paraprocts vestigial or absent.Published as part of Dow, Rory A., Afendy, Aqilah & Rahman, Homathevi, 2016, Telosticta fugispinosa sp. nov. from Sabah (Odonata: Zygoptera: Platystictidae), pp. 390-395 in Zootaxa 4103 (4) on pages 390-394, DOI: 10.11646/zootaxa.4103.4.7, http://zenodo.org/record/25577
Fruit flies of Batu Timbang Forest Within Imbak Canyon Conservation Area, Sabah, Malaysia (Diptera: Tephritidae)
No full textCurrent concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease
No full textChronic obstructive pulmonary disease (COPD) is a global health problem. The current therapies for COPD are poorly effective and the mainstays of pharmacotherapy are bronchodilators. A better understanding of the pathobiology of COPD is critical for the development of novel therapies. In the present review, we have discussed the roles of oxidative/aldehyde stress, inflammation/immunity, and chromatin remodeling in the pathogenesis of COPD. An imbalance of oxidants/antioxidants caused by cigarette smoke and other pollutants/biomass fuels plays an important role in the pathogenesis of COPD by regulating redox-sensitive transcription factors (e.g., NF-κB), autophagy and unfolded protein response leading to chronic lung inflammatory response. Cigarette smoke also activates canonical/alternative NF-κB pathways and their upstream kinases leading to sustained inflammatory response in lungs. Recently, epigenetic regulation has been shown to be critical for the development of COPD because the expression/activity of enzymes that regulate these epigenetic modifications have been reported to be abnormal in airways of COPD patients. Hence, the significant advances made in understanding the pathophysiology of COPD as described herein will identify novel therapeutic targets for intervention in COPD
Environmental toxicity, redox signaling and lung inflammation:the role of glutathione
No full textGlutathione (gamma-glutamyl-cysteinyl-glycine, GSH) is the most abundant intracellular antioxidant thiol and is central to redox defense during oxidative stress. GSH metabolism is tightly regulated and has been implicated in redox signaling and also in protection against environmental oxidant-mediated injury. Changes in the ratio of the reduced and disulfide form (GSH/GSSG) can affect signaling pathways that participate in a broad array of physiological responses from cell proliferation, autophagy and apoptosis to gene expression that involve H(2)O(2) as a second messenger. Oxidative stress due to oxidant/antioxidant imbalance and also due to environmental oxidants is an important component during inflammation and respiratory diseases such as chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, acute respiratory distress syndrome, and asthma. It is known to activate multiple stress kinase pathways and redox-sensitive transcription factors such as Nrf2, NF-kappaB and AP-1, which differentially regulate the genes for pro-inflammatory cytokines as well as the protective antioxidant genes. Understanding the regulatory mechanisms for the induction of antioxidants, such as GSH, versus pro-inflammatory mediators at sites of oxidant-directed injuries may allow for the development of novel therapies which will allow pharmacological manipulation of GSH synthesis during inflammation and oxidative injury. This article features the current knowledge about the role of GSH in redox signaling, GSH biosynthesis and particularly the regulation of transcription factor Nrf2 by GSH and downstream signaling during oxidative stress and inflammation in various pulmonary diseases. We also discussed the current therapeutic clinical trials using GSH and other thiol compounds, such as N-acetyl-l-cysteine, fudosteine, carbocysteine, erdosteine in environment-induced airways disease
Dietary polyphenols mediated regulation of oxidative stress and chromatin remodeling in inflammation
No full textPEMIKIRAN FAZLUR RAHMAN TENTANG PENDIDIKAN DAN RELEVANSINYA DALAM DUNIA MODERN
No full textPragmatic education thought-instrumental is a philosophic point of view that blends with the religious viewpoint of abstract speculation in outlining the education. One of renewing Islamic education is Fazlur Rahman. According to him, the goal of Islamic education are as renewal which is the initial step in the Islamization for all aspects of human life.
The study of library (library research) i.e. research sourced from material libraries using a qualitative approach. In this case, the author does exploration of a number of primary data as well as secondary data. The author does an analysis of the concept of Islamic education prespective Fazlur Rahman and relevance against the modern world.
The concept of educational thought Fazlur Rahman i.e. the Qur\u27an as a guide in resolving every problem and the answer and make the human person that are creative, have moral values in accordance with the Qur\u27an. Whereas, education as an alternative to the secular science by receiving updates and tried to enter it with Islamic concepts as for Islamic education renewal effort started from the educational objectives, educational system, learners, educators and the means of education. The relevance of educational thought on modern world Fazlur Rahman now is integration between religion and discrimination through public education, omission of religion and public education, this has been done wrong by the College namely IAIN with try to follow the thinking of education Fazlur Rahman dare change the State Islamic University (UIN)
PEMIKIRAN FAZLUR RAHMAN TENTANG PENDIDIKAN DAN RELEVANSINYA DENGAN DUNIA MODERN
No full textAbstrakFazlur Rahman is one of the renewal figures in the Islamic world who contributes to develop and lure Muslim scholars in the world so that they are moved to continue their struggle to advance the quality of education, especially in the Islamic world. So in this study, the author tries to present how the role of Fazlur Rahman in developing Islamic education in the Islamic world is devoted to his thinking. The method in this study uses analytical methods with thought data processes. Alignment in the development and contribution of a Fazlur Rahman was finally stated and in line with the Constitution of the National Education System No. 20 of 2003, through its articles. In the hope that harmony can advance the quality of National education, so that Fazlur Rahman's dream of developing Islamic education can be realized in the State of Indonesia. Keywords: Fazlur Rahman, Education, Relevance, Modern Worl
The Rahman Polynomials Are Bispectral
No full textIn a very recent paper, M. Rahman introduced a remarkable family of polynomials in two variables as the eigenfunctions of the transition matrix for a nontrivial Markov chain due to M. Hoare and M. Rahman. I indicate here that these polynomials are bispectral. This should be just one of the many remarkable properties enjoyed by these polynomials. For several challenges, including finding a general proof of some of the facts displayed here the reader should look at the last section of this paper.This paper is a contribution to the Vadim Kuznetsov Memorial Issue ‘Integrable Systems and Related Topics’. I am very thankful to a couple of referees who read the paper with great care and pointed out typos as well as ways to improve the presentation. The author was supported in part by NSF Grant # 0603901
The Rahman Polynomials Are Bispectral
No full textIn a very recent paper, M. Rahman introduced a remarkable family of polynomials in two variables as the eigenfunctions of the transition matrix for a nontrivial Markov chain due to M. Hoare and M. Rahman. I indicate here that these polynomials are bispectral. This should be just one of the many remarkable properties enjoyed by these polynomials. For several challenges, including finding a general proof of some of the facts displayed here the reader should look at the last section of this paper.This paper is a contribution to the Vadim Kuznetsov Memorial Issue ‘Integrable Systems and Related Topics’. I am very thankful to a couple of referees who read the paper with great care and pointed out typos as well as ways to improve the presentation. The author was supported in part by NSF Grant # 0603901
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