4 research outputs found
Effect of acute exposure to nonylphenol on biochemical, hormonal, and hematological parameters and muscle tissues residues of Nile tilapia; Oreochromis niloticus
No full textAim: This study is aimed to evaluate some biochemical, hormonal, hematological, and histopathological changes in Nile tilapia, Oreochromis niloticus, after acute exposure to nonylphenol (NP). In addition to detection of NP residues in the fish, muscle tissues for human health concern.
Materials and Methods: A total of 90 apparently healthy Nile tilapia, O. niloticus, were randomly divided into three equal groups; each containing 30 fish (three replicates). Groups 1 and 2 kept as a control and solvent control (acetone), respectively, and Group 3 exposed to NP at a dose level of 500 μg/L water for 7 successive days. Blood and tissue samples were collected 2 times randomly from each group after 7 days from fish exposure to NP and 10 days from exposure stopping.
Results: Fish exposed to NP Group 3 showed anorexia, sluggish movement, erythema of the skin, areas of scales loss, and hemorrhagic ulcers in some areas of body region leading to exposing the viscera. Biochemical results revealed a significant increase in serum total proteins and globulins levels, a highly significant increase in serum alanine aminotransferase and aspartate aminotransferase activities, triglycerides, cholesterol, and creatinine levels, insignificant increase in serum uric acid level, and a highly significant decrease in serum testosterone and estradiol-β17 levels in Group 3 in compare with the control group. Histopathological finding confirms these results. While hematological results of the same group revealed a significant increase in red blood cells count and packed cell volume value, insignificant increase in hemoglobin concentration, leukopenia, lymphopenia, and monocytopenia in compared with the control group. All of these changes appeared after 7 days from fish exposure to NP. Most of these alterations returned toward the normal level after 10 days from stopping exposure to NP. NP residues detected in fish muscle tissues of Group 3 during exposure and after stopping exposure to it.
Conclusion: It is concluded that NP is a toxic pollutant and has an adverse effect on fish health and reproduction as well as accumulates in fish muscle tissues which may cause human health hazard
Protection of Nile tilapia, Oreochromis niloticus from aflatoxin B 1 toxicity by dietary supplementation with Fennel essential oil and Saccharomyces cerevisiae
No full textProtection of Nile tilapia, Oreochromis niloticus from aflatoxin B1 toxicity by dietary supplementation with Fennel essential oil and Saccharomyces cerevisiae
No full textSignificant losses in ration industry especially aquaculture resulting from aflatoxins. The effect of supplementing Nile tilapia diet with Fennel essential oil (FEO) with or without Saccharomyces cerevisiae on negative impacts of aflatoxin B1, AFB1 (200 ppb) for one month was studied. Two hundred and forty Nile tilapia of 26.6 ± 0.12 g (mean ± SE) were divided into eight groups (30 fish/group) with three replicates. G1 was fed on a basal diet only (D1), while G2 was fed on AFB1 (200 ppb) contaminated diet (D2). G3 and G4 were fed on FEO supplemented diets (1 ml/kg diet) with or without AFB1 (200 ppb) (D3 and D4), respectively. G5 and G6 were fed on S. cerevisiae supplemented diets (1 g/kg diet) with or without AFB1 (200 ppb) (D5 and D6), respectively. G7 and G8 were fed on supplemented diets with mixture from FEO (1 ml/kg diet) and S. cerevisiae (1 g/kg diet) with or without AFB1 (200 ppb) (D7 and D8), respectively. The phagocytic assay, protein profile, serum alanine aminotranferase (ALT) and creatinine were measured at the end of feeding period (30 days). The oxidative stress biomarker as catalase activity and malondialdehyde (MDA) and AFB1 residues in liver and musculature were also measured. At the end of feeding period, the phagocytic activity, total blood proteins and catalase activity showed lower significant values in AFB1 exposed fish. Also, AFB1 induced significant rising in levels of ALT, creatinine and MDA with higher residual levels recorded. Meanwhile, the aflatoxicated groups treated with FEO or S. cerevisiae or their mixture revealed significant improvement of mostly all the measured parameters. FEO can successfully relieve AFB1 noxious effects compared with S. cerevisiae in Nile tilapia. Keywords: Aflatoxin B1, Nile tilapia, Fennel essential oil, Saccharomyces cerevisiae, Phagocytic assay, Malondialdehyd
Allergic rhinitis and its impact on asthma (ARIA): achievements in 10 years and future needs
No full textAllergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization workshop in 1999 (published in 2001). ARIA has reclassified AR as mild/moderate-severe and intermittent/persistent. This classification closely reflects patients' needs and underlines the close relationship between rhinitis and asthma. Patients, clinicians, and other health care professionals are confronted with various treatment choices for the management of AR. This contributes to considerable variation in clinical practice, and worldwide, patients, clinicians, and other health care professionals are faced with uncertainty about the relative merits and downsides of the various treatment options. In its 2010 Revision, ARIA developed clinical practice guidelines for the management of AR and asthma comorbidities based on the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) system. ARIA is disseminated and implemented in more than 50 countries of the world. Ten years after the publication of the ARIA World Health Organization workshop report, it is important to make a summary of its achievements and identify the still unmet clinical, research, and implementation needs to strengthen the 2011 European Union Priority on allergy and asthma in children
