16 research outputs found
Ebu Bekr El-Bakıllani’nin metinleşme süreci bağlamında Kur’an savunusu : el-İntisar örneği
No full textİslâm âlimleri, Kur’ân metninin Hz. Peygamber’e vahyedildiği şekilde bize intikal ettiğine dair tarihte pek çok eser kaleme almışlardır. Bu âlimlerden biri de Ebû Bekr el-Bâkıllânî’dir. Onun, Kur’ân tarihi meselelerini ihtiva eden el-İntisâr li’l-Kur’ân kitabı, metnin mushaflaşma sürecine yönelik muhtemel tüm iddia, şüphe, eleştiri ve itirazları barındırması hasebiyle alanında özgün bir eserdir. Biz de bu çalışmada, el-İntisâr’ın Kur’ân tarihindeki önemini ortaya koymaya ve muhtemel iddialara karşı Bâkıllânî’nin savunusunu tespit etmeye çalıştık.Bir giriş ve üç ana bölümden müteşekkil olan araştırmanın ilk bölümünde özet bilgilerle müellifin yaşadığı döneme ve hayatına temas edildikten sonra müellifin eserleri ve el-İntisâr kitabı yazma nüshaları dâhil bütün yönleriyle ele alınmıştır. İkinci bölümde Kur’ân’ın metinleşme süreci sistematik bir şekilde incelenmiştir. Üçüncü ve son bölümde ise metinleşme sürecinde ileri sürülen iddialar ve müellifin bu iddialara verdiği cevaplar üzerinde durulmuştur. Sonuç olarak el-İntisâr’ın, Kur’ân tarihine dair önemli veriler içermesi, metinleşme süreci hakkında ileri sürülen iddiaları ihtiva etmesi, dönemin tartışmalarını yansıtması ve müellifin, bazı Şiî kaynaklarda zikredilen tahrif rivayetlerini aklî çıkarımlar ve naklî verilerle değerlendirmesi sebebiyle önemli bir yere sahip olduğu ve bu alanda önemli bir boşluğu doldurduğu neticesine ulaştık.Muslim scholars have produced extensive works with regards to the transmision of the Qur’ân as revealed to the Prophet Muhammed. A prominent figure among them is Abu Bakr al-Bâqillânî. His book al-Intisâr li al-Qurân is an original work in its field in that it contains all possible claims, doubts, criticisms and objections related to the process of textualization of the Qur’ân. In this study, we reveal the importance of al-Intisâr in the history of the Qur'an and determine the defense of al-Bâqillânî against these possible claims.The first section of the research consists of an introduction, three main sections, and also the summary information about the period and life of the author before al-Intisâr is studied in all aspects including its manuscripts. In the second section, the process of textualization of the Qur’ân is systematically examined. In section three, the claims asserted during the process of textualization and the answers given by the author to these claims are highlighted. Our research demonstrates that al-Intisâr has a significant place as it: contains important data about the history of the Qur’ân and the asserted claims on the process of the textualization, reflects the discussions of the period, and evaluates the reports on the distortion in the Qur’ân mentioned in some Shiite sources with logical deductions and narrative data as well filling an important gap in the field
An electroceutical approach enhances myelination via upregulation of lipid biosynthesis in the dorsal root ganglion
No full textAs the myelin sheath is crucial for neuronal saltatory conduction, loss of myelin in the peripheral nervous system (PNS) leads to demyelinating neuropathies causing muscular atrophy, numbness, foot deformities and paralysis. Unfortunately, few interventions are available for such neuropathies, because previous pharmaceuticals have shown severe side effects and failed in clinical trials. Therefore, exploring new strategies to enhance PNS myelination is critical to provide solution for such intractable diseases. This study aimed to investigate the effectiveness of electrical stimulation (ES) to enhance myelination in the mouse dorsal root ganglion (DRG) - an ex vivo model of the PNS. Mouse embryonic DRGs were extracted at E13 and seeded onto Matrigel-coated surfaces. After sufficient growth and differentiation, screening was carried out by applying ES in the 1-100 Hz range at the beginning of the myelination process. DRG myelination was evaluated via immunostaining at the intermediate (19 days in vitro (DIV)) and mature (30 DIV) stages. Further biochemical analyses were carried out by utilizing ribonucleic acid sequencing, quantitative polymerase chain reaction and biochemical assays at both intermediate and mature myelination stages. Imaging of DRG myelin lipids was carried out via time-of-flight secondary ion mass spectrometry (ToF-SIMS). With screening ES conditions, optimal condition was identified at 20 Hz, which enhanced the percentage of myelinated neurons and average myelin length not only at intermediate (129% and 61%) but also at mature (72% and 17%) myelination stages. Further biochemical analyses elucidated that ES promoted lipid biosynthesis in the DRG. ToF-SIMS imaging showed higher abundance of the structural lipids, cholesterol and sphingomyelin, in the myelin membrane. Therefore, promotion of lipid biosynthesis and higher abundance of myelin lipids led to ES-mediated myelination enhancement. Given that myelin lipid deficiency is culpable for most demyelinating PNS neuropathies, the results might pave a new way to treat such diseases via electroceuticals. © 2022 The Author(s). Published by IOP Publishing Ltd.1
Deep Learning-based Bangla Sign Language Detection with an Edge Device
No full textSign language, often referred to as silent conversation, serves as a visual gesture-based primary communication medium for hearing-impaired individuals. People unable to speak or hear communicate with themselves and general persons with static and dynamic sign languages. To ensure that people who are deaf and unable to talk do not feel excluded from this fast-paced world, it is even more crucial that sign language is incorporated into our culture and that a cost-effective and straightforward method of detecting it be developed. With this goal in mind, an automatic Bangla sign language (BSL) detection system has been developed in this work using deep learning approaches and a Jetson Nano edge device. The deep learning models have been trained with Okkhornama, an open-source database and a custom author-curated dataset of 49 categories and 3,760 images have been used to validate these techniques. These images are preprocessed by auto-orienting and resizing into 416 × 416 pixels in the Roboflow framework. Next, we implemented Detectron2, EfficientDet-D0 with TensorFlow and the PyTorch-built YOLOv7 models. Jetson Nano, a portable and sufficiently dynamic NVIDIA microprocessor, is also utilized in this project to generate an object detection model and infer it from test images in real-time. The Dectectron2 model performed best concerning detection accuracy, with a [email protected] of 94.915 and an AP of 54.814. The YOLOv7 model achieved [email protected] accuracies in detecting various classes from 85 percent to 97 percent and [email protected] from 41 percent to 53 percent. Finally, the YOLOv7 Tiny approach has been used in the Jetson Nano edge device for real-time Bangla sign language detection because of its lowest total training time and frame rate. The proposed system is expected to provide an effective solution for Bangladeshi people suffering from hearing disabilities and the inability to speak in a simple and affordable approach
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
No full text© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
No full text© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research
SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study
No full textnone10020SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 days of surgery. SARS-CoV-2 diagnosis was defined as peri-operative (7 days before to 30 days after surgery); recent (1–6 weeks before surgery); previous (≥7 weeks before surgery); or none. Information on prophylaxis regimens or pre-operative anti-coagulation for baseline comorbidities was not available. Postoperative venous thromboembolism rate was 0.5% (666/123,591) in patients without SARS-CoV-2; 2.2% (50/2317) in patients with peri-operative SARS-CoV-2; 1.6% (15/953) in patients with recent SARS-CoV-2; and 1.0% (11/1148) in patients with previous SARS-CoV-2. After adjustment for confounding factors, patients with peri-operative (adjusted odds ratio 1.5 (95%CI 1.1–2.0)) and recent SARS-CoV-2 (1.9 (95%CI 1.2–3.3)) remained at higher risk of venous thromboembolism, with a borderline finding in previous SARS-CoV-2 (1.7 (95%CI 0.9–3.0)). Overall, venous thromboembolism was independently associated with 30-day mortality (5.4 (95%CI 4.3–6.7)). In patients with SARS-CoV-2, mortality without venous thromboembolism was 7.4% (319/4342) and with venous thromboembolism was 40.8% (31/76). Patients undergoing surgery with peri-operative or recent SARS-CoV-2 appear to be at increased risk of postoperative venous thromboembolism compared with patients with no history of SARS-CoV-2 infection. Optimal venous thromboembolism prophylaxis and treatment are unknown in this cohort of patients, and these data should be interpreted accordingly.openNepogodiev, Dmitri; Simoes, Joana FF; Li, Elizabeth; Picciochi, Maria; Glasbey, James C; Baiocchi, Glauco; Blanco‐Colino, Ruth; Chaudhry, Daoud; AlAmeer, Ehab; El‐Boghdadly, Kariem; Wuraola, Funmilola; Ghosh, Dhruva; Gujjuri, Rohan R; Harrison, Ewen M; Lule, Herman; Kaafarani, Haytham; Khosravi, Mohammad; Kronberger, Irmgard; Leventoğlu, Sezai; Mann, Harvinder; Mclean, Kenneth A; Mengesha, Mengistu Gebreyohanes; Modolo, Maria Marta; Ntirenganya, Faustin; Norman, Lisa; Outani, Oumaima; Pius, Riinu; Pockney, Peter; Qureshi, Ahmad Uzair; Roslani, April Camilla; Satoi, Sohei; Shaw, Catherine; Bhangu, Aneel; Nepogodiev, Dmitri; Omar, Omar M; Ahmed, Waheed‐Ul‐Rahman; Argus, Leah; Ball, Alasdair; Bhangu, Aneel; Bywater, Edward P; Blanco‐Colino, Ruth; Brar, Amanpreet; Chaudhry, Daoud; Dawson, Brett E; Duran, Irani; Elhadi, Muhammed; Glasbey, James C; Gujjuri, Rohan R; Jones, Conor S; Harrison, Ewen M; Kamarajah, Sivesh K; Keatley, James M; Lawday, Samuel; Li, Elizabeth; Mann, Harvinder; Marson, Ella J; Mclean, Kenneth A; Nepogodiev, Dmitri; Norman, Lisa; Ots, Riinu; Outani, Oumaima; Picciochi, Maria; Santos, Irène; Shaw, Catherine; Simoes, Joana FF; Taylor, Elliott H; Trout, Isobel M; Varghese, Chris; Venn, Mary L; Xu, William; Simoes, Joana FF; Dajti, Irida; Gjata, Arben; Kacimi, Salah Eddine Oussama; Boccalatte, Luis; Modolo, Maria Marta; Cox, Daniel; Pockney, Peter; Townend, Philip; Aigner, Felix; Kronberger, Irmgard Elisabeth; Samadov, Elgun; Alderazi, Amer; Hossain, Kamral; Padmore, Greg; Ramshorst, Gabrielle; Lawani, Ismaïl; Cerovac, Anis; Delibegovic, Samir; Baiocchi, Glauco; Gomes, Gustavo Mendonça Ataíde; Buarque, Igor Lima; Gohar, Muhammad; Slavchev, Mihail; Nwegbu, Chukwuemeka; Agarwal, Arnav; Brar, Amanpreet; Martin, Janet; Ng‐Kamstra, Joshua; Modolo, Maria Marta; Olivos, Maricarmen; Lou, Wenhui; Ren, Dong‐Lin; Calvache, Jose Andres; Perez Rivera, Carlos J; Hadzibegovic, Ana Danic; Kopjar, Tomislav; Mihanovic, Jakov; Jiménez, Pablo Mijahil Avilés; Gouvas, Nikolaos; Klat, Jaroslav; Novysedlák, René; Amisi, Nicolas; Christensen, Peter; El‐Hussuna, Alaa; Batista, Sylvia; Lincango‐Naranjo, Eddy; Emile, Sameh; Sandoval, Danilo Alfonso Arévalo; Dhufera, Hailu; Hailu, Samuel; Mengesha, Mengistu G; Kauppila, Joonas H; Arnaud, Alexis P; Demetrashvili, Zaza; Albertsmeier, Markus; Lederhuber, Hans; Löffler, Markus W.; Acquah, Daniel Kwesi; Ofori, Bernard; Tabiri, Stephen; Metallidis, Symeon; Tsoulfas, Georgios; Aguilera‐Arevalo, Maria‐Lorena; Recinos, Gustavo; Mersich, Tamás; Wettstein, Dániel; Ghosh, Dhruva; Kembuan, Gabriele; Milan, Peiman Brouki; Khosravi, Mohammad Hossein; Mozafari, Masoud; Hilmi, Ahmed; Mohan, Helen; Zmora, Oded; Gallo, Gaetano; Pata, Francesco; Pellino, Gianluca; Fujimoto, Yuki; Kuroda, Naoto; Satoi, Sohei; Abou Chaar, Mohamad K.; Ayasra, Faris; Fakhradiyev, Ildar; Hamdun, Intisar Hisham Said; Jin‐Young, Jang; Jamal, Mohammad; Karout, Lina; Elhadi, Muhammed; Gulla, Aiste; Rasoaherinomenjanahary, Fanjandrainy; Samison, Luc Hervé; Roslani, April Camilla; Sánchez, Iran Irani Durán; Gonzalez, Diana Samantha; Martinez, Laura; Martínez, María José; Nayen, Alejandra; Medina, Antonio Ramos‐De; Nunez, Jade; Outani, Oumaima; Nashidengo, Pueya Rashid; Shah, Rakesh; Shrestha, Ashish Lal; Jonker, Pascal; Kruijff, Schelto; Noltes, Milou; Steinkamp, Pieter; Varghese, Chris; Wright, Deborah; Abdur‐Rahman, Lukman; Ademuyiwa, Adesoji; Adisa, Adewale; Osinaike, Babatunde; Seyi‐Olajide, Justina; Williams, Omolara; Williams, Emmanuel; Pejkova, Sofija; Al Balushi, Zainab; Qureshi, Ahmad Uzair; Sayyed, Raza; Mohsen, Mustafa Abo; Abukhalaf, Sadi A.; Cukier, Moises; Gomez‐Fernandez, Hugo; Yip, Sebastian Shu; Ojeda, Ximena Paola Vasquez; Sacdalan, Marie Dione; Major, Piotr; Azevedo, José; Cunha, Miguel F.; Santos, Irène; Zarour, Ahmad; Bonci, Eduard‐Alexandru; Negoi, Ionut; Efetov, Sergey; Kochetkov, Viktor; Litvin, Andrey; Ingabire, Jc Allen; Bucyibaruta, Georges; Faustin, Ntirenganya; Habumuremyi, Sosthene; Imanishimwe, Alphonsine; Dieu, Haragirimana Jean; Munyaneza, Emmanuel; Ncogoza, Isaie; Alameer, Ehab; Ndong, Abdourahmane; Radenkovic, Dejan; Chew, Min Hoe; Koh, Frederick; Ngu, James; Panyko, Arpád; Bele, Uros; Košir, Jurij Aleš; Daoud, Hassan; Blanco‐Colino, Ruth; Bravo, Ana Maria Minaya; Jayarajah, Umesh; Wickramasinghe, Dakshitha; Adam, Mohammed Elmujtba Adam Essa; Rutegård, Martin; Sund, Malin; Adamina, Michel; Gialamas, Eleftherios; Horisberger, Karoline; Alshaar, Muhammad; Huang, Abel; Lohsiriwat, Varut; Charles, Shane; Jlassi, Haithem; Isik, Arda; Leventoğlu, Sezai; Lekuya, Hervé Monka; Lekuya, Hervé Monka; Lule, Herman; Kopetskyi, Slava; Alsaadi, Hayder; Alshryda, Sattar; Alser, Osaid; Bankhead‐Kendall, Brittany; Breen, Kerry; Kaafarani, Haytham; Mashbari, Hassan; Cal, Fernando Bonilla; Al‐Naggar, Hamza; Maimbo, Mayaba; Mazingi, Dennis; Abbott, Tom; Adamina, Michel; Akhbari, Melika; Benson, Ruth; Bhanderi, Shivam; Biccard, Bruce; Caruana, Edward; Chakrabortee, Sohini; Chapatwala, Reema; Costas‐Chavarri, Ainhoa; Demetriades, Andreas K; Desai, Anant; Di Saverio, Salomone; Drake, Thomas; Edwards, John; Evans, Jonathan; Fiore, Marco; Ford, Samuel; Fotopoulou, Christina; Fowler, Alexander; Futaba, Kaori; Ganly, Ian; James, Harelimana Grace; Griffiths, Ewen; Gronchi, Alessandro; Hutchinson, Peter; Hyman, Gabriella Yael; Incorvia, Joseph; Jain, Ritu; Jenkinson, Michael; Khan, Tabassum; Knight, Stephen Richard; Kolias, Angelos; Kudsk‐Iversen, Søren; Kwan, Tsun Yu; Leung, Elaine; Mayol, Julio; McKay, Siobhan; Meara, John G.; Mills, Emily; Moug, Susan; Patel, Akshay; Perinotti, Roberto; Rice, Henry E.; Roberts, Keith; Schache, Andrew; Shaw, Richard; Smart, Neil; Stephens, Matthew; Stewart, Grant D.; Teasdale, Ella; Vaughan‐Shaw, Peter; Vidya, Raghavan; Wright, Naomi; Wuraola, Funmilola; Zimmelman, Natalie; Agastra, Ervis; Thereska, Dariel; Dajti, Irida; Lucchini, Sergio Martin; Laudani, Veronica; Boccalatte, Luis; Chwat, Carina; Salazar, Ivana Ines Pedraza; Pantoja Pachajoa, Diana Alejandra; Lucchini, Sergio Martin; Duro, Agustin; Arancibia, José Alfredo Calderón; Cox, Daniel; D’Aulerio, Giuliana; Dudi‐Venkata, Nagendra; Egoroff, Natasha; Farik, Shebani; Lott, Natalie; Moss, Jana‐Lee; Rennie, Sarah; Tan, Lorwai; Varghese, Chris; Vo, Uyen Giao; Watson, David; Watters, David; Wright, Deborah; Bright, Tim; Hollington, Paul; Zhou, Xuanyu; Kroon, Hidde M; Farfus, Anthony; Barker, John; Watson, Eleanor; Stevens, Sean; Latif, Haider; Dawson, Amanda Caroline; Chuan, Alwin; Muralidharan, Vijayaragavan; Wong, Enoch; Ackermann, Travis; Pacilli, Maurizio; Hodgson, Russell; Heriot, Alexander; Choong, Peter; Brown, Wendy; Lidder, Surjit; Yeung, Justin; Traeger, Luke; Regalo, Guillermo; Gourlay, Ralph; Pockney, Peter; Pockney, Peter; Badiani, Sarit; Koh, Cherry; Putnis, Soni; Dawson, Amanda Caroline; Haider, Fayza; Mitul, Ashrarur Rahman; Komen, Niels; Dhondt, Bert; Cappeliez, Serge; Pigeolet, Manon; Ramshorst, Gabrielle; Schoneveld, Martijn; Stijns, Jasper; Oosterlinck, Wouter; Flamey, Nicolas; Kpangon, Cyrille; Agbadebo, Mouhamed; Tobome, Smèvo Romaric; Lawani, Ismaïl; Cerovac, Anis; Barros, Aldo Vieira; Júnior, Samuel Aguiar; Baiocchi, Glauco; Amaral Campos, Heloisa Galvão; Gross, Jefferson; Coimbra, Felipe José Fernandez; Kowalski, Luiz Paulo; Makdissi, Fabiana; Nakagawa, Suely; Neto, Joao Pedreira Duprat; Vartanian, Jose Guilherme; Yazbek, Guilherme; Zequi, Stenio C; Flumignan, Ronald; Slavchev, Mihail; Jaworska, Natalia; Dell, Angela; Shanthanna, Harsha; Martin, Janet; Behzadi, Abdollah; Nessim, Carolyn; Mozel, Michelle; St‐germain, Pascal; Russell, Crispin; Groot, Gary; Safieddine, Najib; Wijeysundera, Duminda; Eskander, Antoine; Chadi, Sami; MacKenzie, Shawn; Flexman, Alana; Heredia, Fernando; Modolo, Maria Marta; Villanueva, Julio; Waissbluth, Sofia; Macchiavello, Roberto; Escudero, Mario I; Fuentes, Tyare; Mimica, Ximena; Olivos, Maricarmen; Saenz, Dinimo Bolivar; Caicedo, Lina; Alzate, Juan Pablo; Luna, Joaquin; Alonso, Nestor Fabian Pedraza; Silva, Camilo Ortiz; Perez Rivera, Carlos J; Rodriguez, Juliana; Silva‐Igua, Liliana; Torres, Martha Luz; Trujillo, Lina María; Calvache, Albaro José Nieto; Balanta‐Melo, Julián; Figueroa‐Casanova, Rafael; García‐Montoya, Oscar‐Julián; Toro, Carlos Andres Marulanda; Botero, Marcela Velez; Arango, Maria Clara Mendoza; Martinez, Eneida Diaz; Perdomo, Valentina Gutiérrez; Calvache, Jose Andres; Calvache, Jose Andres; Montenegro, Emileth; Mihanovic, Jakov; Jiménez, Pablo Mijahil Avilés; Gouvas, Nikolaos; Novysedlák, René; Rodriguez‐Abreu, Julia; Mejía, Dolores; Lincango‐Naranjo, Eddy; Abouelnagah, Galal; Shehata, Sameh; Rida, Ahmed Hossam Eldin Fouad; Hassan, Ramy A.; Saad, Mahmoud M.; Loaloa, Mohamed Reda; Mostafa, Badr; Qassem, Mohamed; Fahmy, Mohamed; Abozied, Hesham; Azzam, Ahmed Y; Ghozy, Sherief; Sallam, Asser; Shehta, Ahmed; Emile, Sameh; Abdelkhalek, Mohamed; Samaka, Rehab; Morsy, Amr; Sherif, Ahmed Elshawadfy; Sandoval, Danilo Alfonso Arévalo; Negussie, Abraham; Fisseha, Tigist; Shumbash, Kibruyisfaw; Abebe, Metasebia; Hailu, Samuel; Yasin, Seid Mohammed; Akililu, Yemisirach Bizuneh; Megersa, Abebe; Tefera, Teshome; Assefa, Melatework; Atnafu, Bahru; Tsegaye, Bereket; Bezabih, Yoseph Solomon; Sisay, Silamlak; Bekele, Kebebe; Jira, Moa; Mengesha, Mengistu G; Derilo, Habtamu; Degefa, Eyueal; Tadesse, Anteneh; Nidaw, Melkamu; Sarjanoja, Elise; Kauppila, Joonas H; Testelin, Sylvie; Boucher, Sophie; Jouffret, Lionel; Lakkis, Zaher; Le Bian, Alban Zarzavadjian; Harper, Luke; Déserts, Marc Danguy; André, Benoît; Slim, Karem; Verhaeghe, Romain; Police, Andrea; Girard, Edouard; Chebaro, Alexandre; Nkembi, Armande Subayi; Arnalsteen, Laurent; Ballouhey, Quentin; Mege, Diane; Jeandel, Clement; Duchalais, Emilie; Bouche, Pierre‐Alban; Manceau, Gilles; Crétolle, Célia; Hervieux, Erik; Girard, Noémie; Seguin‐Givelet, Agathe; Gaujoux, Sebastien; De Simone, Belinda; Boisson, Matthieu; Bergeat, Damien; Arnaud, Alexis P; Fredon, Fabien; Nappi, Francesco; Kassir, Radwan; Scalabre, Aurélien; Migliorelli, Federico; Verhaeghe, Romain; Ezanno, Anne‐Cecile; Seeliger, Barbara; Vaysse, Charlotte; Charbonneau, Helene; Misrai, Vincent; Abbo, Olivier; Angeles, Martina Aida; Brunaud, Laurent; Demetrashvili, Zaza; Modabber, Ali; Wolf, Sebastian; Kamphues, Carsten; Höhn, Philipp; Glowka, Tim R.; Rokohl, Alexander Christopher; Bork, Ulrich; Fluegen, Georg; Horch, Raymund E.; Schmedding, Andrea; Schnitzbauer, Andreas; Eberbach, Helge; Schlager, Daniel; Spelsberg, Fritz; Keppler, Lena; Hecker, Andreas; Wolfer, Susanne; Ronellenfitsch, Ulrich; Nitschke, Christine; Peiper, Christian; Hakami, Ibrahim; Welter, Stefan; Nikolaieva, Karine; Roth, Andreas; Lindert, Judith; Gousias, Konstantinos; Rissmann, Anke; Linz, Valerie Catherine; Rahbari, Nuh; Rassweiler‐Seyfried, Marie‐Claire; Gut, Anna Eleonora; Gempt, Jens; Reim, Daniel; Wagner, Arthur; Albertsmeier, Markus; Keppler, Alexander M.; Stoleriu, Mircea Gabriel; Saier, Tim; Stadler, Josef; Kaiser, Julia Christina; 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Bajaj, Ankur; Rajan, Shiv; Agarwal, Gaurav; Pawar, Pranay; Alexander, Philip; Vijayakumar, M Vijayakumar; Hameed, Zeeshan; Badareesh, L; Chaudhry, Navneet Kumar; Baliarsing, Lipika; Dharap, Satish; Kulkarni, Amruta; Thyavihally, Yuvaraja; Sharma, Rahul Deo; Pramesh, C S; Soni, Rajesh; Dube, Surya Kumar; Sharma, Shilpa; Singh, Harvinder; Bains, Lovenish; Ghodke, Rahul; Kumar, Ashwani; Sodhai, Vivek; Maji, Suvendu; Basu, Somprakas; Mahakalkar, Chandrashekhar; Kannan, Ravi; Mehraj, Asif; Ranganath, N; Phadnis, Ashish; Yadev, I; Kavalakat, Alfie; Mittal, Rohin; Vallam, Karthik Chandra; Akhavizadegan, Hamed; Maleki, Esmaeil Rezghi; Kandevani, Naser Yousefzadeh; Ikele, Hilary; McNestry, Catherine; Fleming, Christina; O’Brien, Stephen; Elwahab, Sami Abd; Davis, Niall; Javadpour, Mohsen; McDonnell, Brendan; Connor, Clare O; Bolger, Jarlath; Clancy, Cillian; Croghan, Stefanie M; Donlon, Noel; Cullinane, Carolyn; Creavin, Ben; Muheilan, Muheilan; Earley, Helen; Kabir, Syed Mohammad Umar; Fahadullah, Muhammad; 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Burgan, Dania; Abdelkabir, Mohammed; Alshareef, Khayriyah; Islam Ben Jouira, Rayet; Meelad, Ayman; Bouhuwaish, Ahmad; Dwaga, Sumayya Essayah; Khalifa, Houda; Almiqlash, Bushray; Suliaman, Taha; Alawami, Mohammed; Elhajdawe, Fras; Aboazamazem, Hajir; Ellojli, Ibrahim; Msherghi, Ahmed; Saleh, Ismail Ali; Alayan, Mohammed; Roslani, April Camilla; Ndayishyigikiye, Marcel Didier; Munyika, Akutu; Plarre, Philipp; Borowski, David W; Nashidengo, Pueya Rashid; Noltes, Milou; Steinkamp, Pieter; Wells, Cameron; Teague, Rebecca; Elliott, Brodie; Kieser, David; Mohyieldin, Omar; Varghese, Chris; McIntosh, Nick; Haran, Cheyaanthan; Rennie, Sarah; King, Jasmin; Ha, Jeong; McGuinness, Matthew James; Adesanya, Opeoluwa; Olaogun, Julius; Akinmade, Akinola; Bwala, Kefas; Agbonrofo, Peter; Afolabi, Akinwale; Usang, Usang; Ekenze, Sebastian; Olori, Samson; Lawal, Taiwo Akeem; Seyi‐Olajide, Justina; Okunlola, Abiodun; Williams, Omolara; Adisa, Adewale; Abdur‐Rahman, Lukman; Kache, Stephen; Sale, Danjuma; Anyanwu, Lofty‐John; Okereke, Chukwuma; Tolani, Musliu Adetola; Filipce, Venko; Todorovic, Lazar; Pejkova, Sofija; Stavridis, Sotir; Massoud, John George; Alsibai, Sareyah; Sultan, Rizwan; Altaf, Humera Naz; Bhatti, Abu Bakar Hafeez; Waqar, Shahzad Hussain; Aziz, Aliya; Kerawala, Asad Ali; Rai, Lajpat; Anwer, Mariyah; Tariq, Aiman; Ayub, Bushra; Niazi, Sami Ullah; Naseem, Muhammad Yasir; Sarwar, Muhammad Zeeshan; Khokhar, Muhammad Imran; Zahid, Imdad Ahmad; Majid, Haroon Javaid; Talat, Nabila; Asif, Muhammad; Chaudhary, Muhammad Hamid; Farooq, Umer; Ahmad, Siddique; Mabood, Waleed; Bukhari, Syed Imran; Tariq, Muhammad; Yaqoob, Eesha; Javed, Saad; Javed, Saad; Malik, Muhammad Usman; Yaqoob, Hassan Nawaz; Cukier, Moises; Pacheco, Glenda Marina Falcon; Melendez, Robinson Mas; Urbina, Arazzelly Del Pilar Paucar; Chiuyari, Jose Rios; Alvarado, Carlos Eduardo Otiniano; Lau, Lorena Fuentes Rivera; Borda‐Luque, Giuliano; Niquen‐Jimenez, Milagros; Arias, Claudia; Zegarra, Sergio; Pallardel, Jenner Betalleluz; Oscco, Regina Amparo Ugarte; Mendiola, Gian; Colmenares, Yahaira Tatiana Carpio; Zapata, Carlos Shiraishi; Ortiz, Maria Rosa; Sacdalan, Marie Dione; Major, Piotr; Borges, Filipe Castro; Viveiros, Octavio; Serralheiro, Pedro; Santos‐Costa, Paulo; Mendes, Filipa; Melo, Miguel Rocha; Cardoso, Paulo; Soares, Ana; Azevedo, José; Pereira, Rita Gonçalves; Silva, Nelson; Caiado, André; Sacras, Maria Luís; Azevedo, Pedro; Almeida‐Reis, Rui; Cunha, Miguel F.; Oliveira, João; Nogueiro, Jorge; Sampaio‐Alves, Mafalda; Costa, Luciana Cidade; Baía, Catarina; Deus, Ana Cláudia; Branquinho, Rita; Marçal, André; Tojal, André; Zarour, Ahmad; Zarour, Ahmad; Makkai‐Popa, Silviu Tiberiu; Mironescu, Aurel; Grama, Florin; Toma, Elena Adelina; Negoi, Ionut; Filipescu, Daniela; Bacalbasa, Nicolae; Motas, Natalia; Ionescu, Sebastian; Ginghina, Octav; Costea, Radu; Zarnescu, Narcis Octavian; Drasovean, Radu; Bonci, Eduard‐Alexandru; Dimofte, Mihail‐Gabriel; Porumb, Vlad; Kirov, Mikhail; Molitvin, Yegor; Litvin, Andrey; Pykhteev, Vadim; Raevskaya, Marianna; Efetov, Sergey; Butyrskii, Aleksandr; Alshahrani, Mushabab; Althumairi, Azah; Alzerwi, Nasser; Al Ameer, Ahmed; Al Ameer, Ahmed; Madkhali, Tariq; Almulhim, Abddulrahman Saleh; Ghazwani, Salman; Ayoub, Abdu; Iskander, Othman; Ghunaim, Mohammed; Alharthi, Mohammed; Alzaidi, Turki M; Althumairi, Azah; Alyami, Mohammad; Al Amri, Abdulrahman; Althumairi, Azah; AlFakhri, Abdullah; Alhefdhi, Amal; Chowdhury, Sharfuddin; Nouh, Thamer; Alshehri, Ameen; Alzahrani, Abdulrahman; Alalawi, Yousef; Awad, Selmy; Konate, Ibrahima; Ndong, Abdourahmane; Tendeng, Jacques; Teo, Nan Zun; Koh, Frederick; Košir, Jurij Aleš; Bele, Uros; Aqil, Sabra; López, Cristina Barrena; Mozo, Ana Sánchez; Infante, Antonio Rodriguez; Vivancos, Patricia Caja; Prieto, Mikel; Roman, Igor Alberdi San; Fernandez, Laura Gomez; Vives, Josep Maria Muñoz; Carreras‐Castañer, Anna; Díaz‐Feijoo, Berta; Sieira‐Gil, Ramon; Turrado‐Rodriguez, Victor; López, Anna Sánchez; Sánchez‐Cabús, Santiago; Toscano, Marta Jimenez; Sin, MªPilar Canals; Laura, Saura García; Sole, Oriol Martin; Bellver, Pedro Palazon; Pérez‐Bertólez, Sonia; Prat‐Ortells, Jordi; Martínez, Mireia Riba; Rubio‐Palau, Josep; Tarrado, Xavier; Nuñez, Jorge; Mendoza, Veronica Alonso; Bescós, Coro; Espin‐Basany, Eloy; Espinosa‐Bravo, Martin; Gil‐Sala, Daniel; González‐Suárez, Susana; Estruch, Nuria Montferrer; Nuñez, Jorge; Mariño, Lucia Porteiro; Rodríguez‐Tesouro, Ana; Portilla, Fabian Rojas; Pérez, M Pilar Tormos; Vives, Inmaculada; De Cortazar, Unai Garcia; Tudela, Kiara; Landaluce‐Olavarria, Aitor; Gómez, Mercedes Estaire; Almoguera, Jorge; Ugarte‐Sierra, Bakarne; Jimenez, Virginia; Bertrand, Marta; Puiggrós, Laura Cárdenas; Delisau‐Puig, Olga; Garcia‐Adamez, Jorge; Bergkvist, David Julià; Maldonado‐Marcos, Eloy; García, Lucia Diego; Golet, Marta Roldón; Soto‐Darias, Iván; Rahy‐Martín, Aida Cristina; Enjuto, Diego; Ramos‐Luengo, Adolfo; Fernandez, Juan Delgado; Duarte, Carolina Lugo; Thies, Cristina Ojeda; Marquez, Lucila; Vita, Diana Crego; Dziakova, Jana; 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Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study
No full text32324restrictedrestrictedDmitri Nepogodiev; Joana Ff Simoes; Elizabeth Li; Maria Picciochi; James C Glasbey; Glauco Baiocchi; Ruth Blanco-Colino; Daoud Chaudhry; Ehab AlAmeer; Kariem El-Boghdadly; Funmilola Wuraola; Dhruva Ghosh; Rohan R Gujjuri; Ewen M Harrison; Herman Lule; Haytham Kaafarani; Mohammad Khosravi; Irmgard Kronberger; Sezai Leventoğlu; Harvinder Mann; Kenneth A Mclean; Mengistu Gebreyohanes Mengesha; Maria Marta Modolo; Faustin Ntirenganya; Lisa Norman; Oumaima Outani; Riinu Pius; Peter Pockney; Ahmad Uzair Qureshi; April Camilla Roslani; Sohei Satoi; Catherine Shaw; Aneel Bhangu; Dmitri Nepogodiev; Omar M Omar; Waheed-Ul-Rahman Ahmed; Leah Argus; Alasdair Ball; Aneel Bhangu; Edward P Bywater; Ruth Blanco-Colino; Amanpreet Brar; Daoud Chaudhry; Brett E Dawson; Irani Duran; Muhammed Elhadi; James C Glasbey; Rohan R Gujjuri; Conor S Jones; Ewen M Harrison; Sivesh K Kamarajah; James M Keatley; Samuel Lawday; Elizabeth Li; Harvinder Mann; Ella J Marson; Kenneth A Mclean; Dmitri Nepogodiev; Lisa Norman; Riinu Ots; Oumaima Outani; Maria Picciochi; Irène Santos; Catherine Shaw; Joana Ff Simoes; Elliott H Taylor; Isobel M Trout; Chris Varghese; Mary L Venn; William Xu; Joana Ff Simoes; Irida Dajti; Arben Gjata; Salah Eddine Oussama Kacimi; Luis Boccalatte; Maria Marta Modolo; Daniel Cox; Peter Pockney; Philip Townend; Felix Aigner; Irmgard Elisabeth Kronberger; Elgun Samadov; Amer Alderazi; Kamral Hossain; Greg Padmore; Gabrielle van Ramshorst; Ismaïl Lawani; Anis Cerovac; Samir Delibegovic; Glauco Baiocchi; Gustavo Mendonça Ataíde Gomes; Igor Lima Buarque; Muhammad Gohar; Mihail Slavchev; Chukwuemeka Nwegbu; Arnav Agarwal; Amanpreet Brar; Janet Martin; Joshua Ng-Kamstra; Maria Marta Modolo; Maricarmen Olivos; Wenhui Lou; Dong-Lin Ren; Jose Andres Calvache; Carlos J Perez Rivera; Ana Danic Hadzibegovic; Tomislav Kopjar; Jakov Mihanovic; Pablo Mijahil Avilés Jiménez; Nikolaos Gouvas; Jaroslav Klat; René Novysedlák; Nicolas Amisi; Peter Christensen; Alaa El-Hussuna; Sylvia Batista; Eddy Lincango-Naranjo; Sameh Emile; Danilo Alfonso Arévalo Sandoval; Hailu Dhufera; Samuel Hailu; Mengistu G Mengesha; Joonas H Kauppila; Alexis P Arnaud; Zaza Demetrashvili; Markus Albertsmeier; Hans Lederhuber; Markus W Löffler; Daniel Kwesi Acquah; Bernard Ofori; Stephen Tabiri; Symeon Metallidis; Georgios Tsoulfas; Maria-Lorena Aguilera-Arevalo; Gustavo Recinos; Tamás Mersich; Dániel Wettstein; Dhruva Ghosh; Gabriele Kembuan; Peiman Brouki Milan; Mohammad Hossein Khosravi; Masoud Mozafari; Ahmed Hilmi; Helen Mohan; Oded Zmora; Gaetano Gallo; Francesco Pata; Gianluca Pellino; Yuki Fujimoto; Naoto Kuroda; Sohei Satoi; Mohamad K Abou Chaar; Faris Ayasra; Ildar Fakhradiyev; Intisar Hisham Said Hamdun; Jang Jin-Young; Mohammad Jamal; Lina Karout; Muhammed Elhadi; Aiste Gulla; Fanjandrainy Rasoaherinomenjanahary; Luc Hervé Samison; April Camilla Roslani; Iran Irani Durán Sánchez; Diana Samantha Gonzalez; Laura Martinez; María José Martínez; Alejandra Nayen; Antonio Ramos-De la Medina; Jade Nunez; Oumaima Outani; Pueya Rashid Nashidengo; Rakesh Shah; Ashish Lal Shrestha; Pascal Jonker; Schelto Kruijff; Milou Noltes; Pieter Steinkamp; Chris Varghese; Deborah Wright; Lukman Abdur-Rahman; Adesoji Ademuyiwa; Adewale Adisa; Babatunde Osinaike; Justina Seyi-Olajide; Omolara Williams; Emmanuel Williams; Sofija Pejkova; Zainab Al Balushi; Ahmad Uzair Qureshi; Raza Sayyed; Mustafa Abo Mohsen; Sadi A Abukhalaf; Moises Cukier; Hugo Gomez-Fernandez; Sebastian Shu Yip; Ximena Paola Vasquez Ojeda; Marie Dione Sacdalan; Piotr Major; José Azevedo; Miguel F Cunha; Irène Santos; Ahmad Zarour; Eduard-Alexandru Bonci; Ionut Negoi; Sergey Efetov; Viktor Kochetkov; Andrey Litvin; Jc Allen Ingabire; Georges Bucyibaruta; Ntirenganya Faustin; Sosthene Habumuremyi; Alphonsine Imanishimwe; Haragirimana Jean de Dieu; Emmanuel Munyaneza; Isaie Ncogoza; Ehab Alameer; Abdourahmane Ndong; Dejan Radenkovic; Min Hoe Chew; Frederick Koh; James Ngu; Arpád Panyko; Uros Bele; Jurij Aleš Košir; Hassan Daoud; Ruth Blanco-Colino; Ana Maria Minaya Bravo; Umesh Jayarajah; Dakshitha Wickramasinghe; Mohammed Elmujtba Adam Essa Adam; Martin Rutegård; Malin Sund; Michel Adamina; Eleftherios Gialamas; Karoline Horisberger; Muhammad Alshaar; Abel Huang; Varut Lohsiriwat; Shane Charles; Haithem Jlassi; Arda Isik; Sezai Leventoğlu; Hervé Monka Lekuya; Hervé Monka Lekuya; Herman Lule; Slava Kopetskyi; Hayder Alsaadi; Sattar Alshryda; Osaid Alser; Brittany Bankhead-Kendall; Kerry Breen; Haytham Kaafarani; Hassan Mashbari; Fernando Bonilla Cal; Hamza Al-Naggar; Mayaba Maimbo; Dennis Mazingi; Tom Abbott; Michel Adamina; Melika Akhbari; Ruth Benson; Shivam Bhanderi; Bruce Biccard; Edward Caruana; Sohini Chakrabortee; Reema Chapatwala; Ainhoa Costas-Chavarri; Andreas K Demetriades; Anant Desai; Salomone Di Saverio; Thomas Drake; John Edwards; Jonathan Evans; Marco Fiore; Samuel Ford; Christina Fotopoulou; Alexander Fowler; Kaori Futaba; Ian Ganly; Harelimana Grace James; Ewen Griffiths; Alessandro Gronchi; Peter Hutchinson; Gabriella Yael Hyman; Joseph Incorvia; Ritu Jain; Michael Jenkinson; Tabassum Khan; Stephen Richard Knight; Angelos Kolias; Søren Kudsk-Iversen; Tsun Yu Kwan; Elaine Leung; Julio Mayol; Siobhan McKay; John G Meara; Emily Mills; Susan Moug; Akshay Patel; Roberto Perinotti; Henry E Rice; Keith Roberts; Andrew Schache; Richard Shaw; Neil Smart; Matthew Stephens; Grant D Stewart; Ella Teasdale; Peter Vaughan-Shaw; Raghavan Vidya; Naomi Wright; Funmilola Wuraola; Natalie Zimmelman; Ervis Agastra; Dariel Thereska; Irida Dajti; Sergio Martin Lucchini; Veronica Laudani; Luis Boccalatte; Carina Chwat; Ivana Ines Pedraza Salazar; Diana Alejandra Pantoja Pachajoa; Sergio Martin Lucchini; Agustin Duro; José Alfredo Calderón Arancibia; Daniel Cox; Giuliana D'Aulerio; Nagendra Dudi-Venkata; Natasha Egoroff; Shebani Farik; Natalie Lott; Jana-Lee Moss; Sarah Rennie; Lorwai Tan; Chris Varghese; Uyen Giao Vo; David Watson; David Watters; Deborah Wright; Tim Bright; Paul Hollington; Xuanyu Zhou; Hidde M Kroon; Anthony Farfus; John Barker; Eleanor Watson; Sean Stevens; Haider Latif; Amanda Caroline Dawson; Alwin Chuan; Vijayaragavan Muralidharan; Enoch Wong; Travis Ackermann; Maurizio Pacilli; Russell Hodgson; Alexander Heriot; Peter Choong; Wendy Brown; Surjit Lidder; Justin Yeung; Luke Traeger; Guillermo Regalo; Ralph Gourlay; Peter Pockney; Peter Pockney; Sarit Badiani; Cherry Koh; Soni Putnis; Amanda Caroline Dawson; Fayza Haider; Ashrarur Rahman Mitul; Niels Komen; Bert Dhondt; Serge Cappeliez; Manon Pigeolet; Gabrielle van Ramshorst; Martijn Schoneveld; Jasper Stijns; Wouter Oosterlinck; Nicolas Flamey; Cyrille Kpangon; Mouhamed Agbadebo; Sèmèvo Romaric Tobome; Ismaïl Lawani; Anis Cerovac; Aldo Vieira Barros; Samuel Aguiar Júnior; Glauco Baiocchi; Heloisa Galvão do Amaral Campos; Jefferson Gross; Felipe José Fernandez Coimbra; Luiz Paulo Kowalski; Fabiana Makdissi; Suely Nakagawa; Joao Pedreira Duprat Neto; Jose Guilherme Vartanian; Guilherme Yazbek; Stenio C Zequi; Ronald Flumignan; Mihail Slavchev; Natalia Jaworska; Angela Dell; Harsha Shanthanna; Janet Martin; Abdollah Behzadi; Carolyn Nessim; Michelle Mozel; Pascal St-Germain; Crispin Russell; Gary Groot; Najib Safieddine; Duminda Wijeysundera; Antoine Eskander; Sami Chadi; Shawn MacKenzie; Alana Flexman; Fernando Heredia; Maria Marta Modolo; Julio Villanueva; Sofia Waissbluth; Roberto Macchiavello; Mario I Escudero; Tyare Fuentes; Ximena Mimica; Maricarmen Olivos; Dinimo Bolivar Saenz; Lina Caicedo; Juan Pablo Alzate; Joaquin Luna; Nestor Fabian Pedraza Alonso; Camilo Ortiz Silva; Carlos J Perez Rivera; Juliana Rodriguez; Liliana Silva-Igua; Martha Luz Torres; Lina María Trujillo; Albaro José Nieto Calvache; Julián Balanta-Melo; Rafael Figueroa-Casanova; Oscar-Julián García-Montoya; Carlos Andres Marulanda Toro; Marcela Velez Botero; Maria Clara Mendoza Arango; Eneida Diaz Martinez; Valentina Gutiérrez Perdomo; Jose Andres Calvache; Jose Andres Calvache; Emileth Montenegro; Jakov Mihanovic; Pablo Mijahil Avilés Jiménez; Nikolaos Gouvas; René Novysedlák; Julia Rodriguez-Abreu; Dolores Mejía; Eddy Lincango-Naranjo; Galal Abouelnagah; Sameh Shehata; Ahmed Hossam Eldin Fouad Rida; Ramy A Hassan; Mahmoud M Saad; Mohamed Reda Loaloa; Badr Mostafa; Mohamed Qassem; Mohamed Fahmy; Hesham Abozied; Ahmed Y Azzam; Sherief Ghozy; Asser Sallam; Ahmed Shehta; Sameh Emile; Mohamed Abdelkhalek; Rehab Samaka; Amr Morsy; Ahmed Elshawadfy Sherif; Danilo Alfonso Arévalo Sandoval; Abraham Negussie; Tigist Fisseha; Kibruyisfaw Shumbash; Metasebia Abebe; Samuel Hailu; Seid Mohammed Yasin; Yemisirach Bizuneh Akililu; Abebe Megersa; Teshome Tefera; Melatework Assefa; Bahru Atnafu; Bereket Tsegaye; Yoseph Solomon Bezabih; Silamlak Sisay; Kebebe Bekele; Moa Jira; Mengistu G Mengesha; Habtamu Derilo; Eyueal Degefa; Anteneh Tadesse; Melkamu Nidaw; Elise Sarjanoja; Joonas H Kauppila; Sylvie Testelin; Sophie Boucher; Lionel Jouffret; Zaher Lakkis; Alban Zarzavadjian Le Bian; Luke Harper; Marc Danguy des Déserts; Benoît André; Karem Slim; Romain Verhaeghe; Andrea Police; Edouard Girard; Alexandre Chebaro; Armande Subayi Nkembi; Laurent Arnalsteen; Quentin Ballouhey; Diane Mege; Clement Jeandel; Emilie Duchalais; Pierre-Alban Bouche; Gilles Manceau; Célia Crétolle; Erik Hervieux; Noémie Girard; Agathe Seguin-Givelet; Sebastien Gaujoux; Belinda De Simone; Matthieu Boisson; Damien Bergeat; Alexis P Arnaud; Fabien Fredon; Francesco Nappi; Radwan Kassir; Aurélien Scalabre; Federico Migliorelli; Romain Verhaeghe; Anne-Cecile Ezanno; Barbara Seeliger; Charlotte Vaysse; Helene Charbonneau; Vincent Misrai; Olivier Abbo; Martina Aida Angeles; Laurent Brunaud; Zaza Demetrashvili; Ali Modabber; Sebastian Wolf; Carsten Kamphues; Philipp Höhn; Tim R Glowka; Alexander Christopher Rokohl; Ulrich Bork; Georg Fluegen; Raymund E Horch; Andrea Schmedding; Andreas Schnitzbauer; Helge Eberbach; Daniel Schlager; Fritz Spelsberg; Lena Keppler; Andreas Hecker; Susanne Wolfer; Ulrich Ronellenfitsch; Christine Nitschke; Christian Peiper; Ibrahim Hakami; 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Faraj Al Maadany; Ghadah Alkadeeki; Milad Gahwagi; Wafa Aldressi; Mohamed Amnaina; Arowa Hassan Abdulrahman Alansari; Akram Alkaseek; Ghozlan Yagoub; Anass Ben Amer; Marwa Salem; Ayman Almugaddami; Dania Burgan; Mohammed Abdelkabir; Khayriyah Alshareef; Rayet Al Islam Ben Jouira; Ayman Meelad; Ahmad Bouhuwaish; Sumayya Essayah Dwaga; Houda Khalifa; Bushray Almiqlash; Taha Suliaman; Mohammed Alawami; Fras Elhajdawe; Hajir Aboazamazem; Ibrahim Ellojli; Ahmed Msherghi; Ismail Ali Saleh; Mohammed Alayan; April Camilla Roslani; Marcel Didier Ndayishyigikiye; Akutu Munyika; Philipp Plarre; David W Borowski; Pueya Rashid Nashidengo; Milou Noltes; Pieter Steinkamp; Cameron Wells; Rebecca Teague; Brodie Elliott; David Kieser; Omar Mohyieldin; Chris Varghese; Nick McIntosh; Cheyaanthan Haran; Sarah Rennie; Jasmin King; Jeong Ha; Matthew James McGuinness; Opeoluwa Adesanya; Julius Olaogun; Akinola Akinmade; Kefas Bwala; Peter Agbonrofo; Akinwale Afolabi; Usang Usang; Sebastian Ekenze; Samson Olori; Taiwo Akeem Lawal; Justina Seyi-Olajide; Abiodun Okunlola; Omolara Williams; Adewale Adisa; Lukman Abdur-Rahman; Stephen Kache; Danjuma Sale; Lofty-John Anyanwu; Chukwuma Okereke; Musliu Adetola Tolani; Venko Filipce; Lazar Todorovic; Sofija Pejkova; Sotir Stavridis; John George Massoud; Sareyah Alsibai; Rizwan Sultan; Humera Naz Altaf; Abu Bakar Hafeez Bhatti; Shahzad Hussain Waqar; Aliya Aziz; Asad Ali Kerawala; Lajpat Rai; Mariyah Anwer; Aiman Tariq; Bushra Ayub; Sami Ullah Niazi; Muhammad Yasir Naseem; Muhammad Zeeshan Sarwar; Muhammad Imran Khokhar; Imdad Ahmad Zahid; Haroon Javaid Majid; Nabila Talat; Muhammad Asif; Muhammad Hamid Chaudhary; Umer Farooq; Siddique Ahmad; Waleed Mabood; Syed Imran Bukhari; Muhammad Tariq; Eesha Yaqoob; Saad Javed; Saad Javed; Muhammad Usman Malik; Hassan Nawaz Yaqoob; Moises Cukier; Glenda Marina Falcon Pacheco; Robinson Mas Melendez; Arazzelly Del Pilar Paucar Urbina; Jose Rios Chiuyari; Carlos Eduardo Otiniano Alvarado; Lorena Fuentes Rivera Lau; Giuliano Borda-Luque; Milagros Niquen-Jimenez; Claudia Arias; Sergio Zegarra; Jenner Betalleluz Pallardel; Regina Amparo Ugarte Oscco; Gian Mendiola; Yahaira Tatiana Carpio Colmenares; Carlos Shiraishi Zapata; Maria Rosa Ortiz; Marie Dione Sacdalan; Piotr Major; Filipe Castro Borges; Octavio Viveiros; Pedro Serralheiro; Paulo Santos-Costa; Filipa Mendes; Miguel Rocha Melo; Paulo Cardoso; Ana Soares; José Azevedo; Rita Gonçalves Pereira; Nelson Silva; André Caiado; Maria Luís Sacras; Pedro Azevedo; Rui Almeida-Reis; Miguel F Cunha; João Oliveira; Jorge Nogueiro; Mafalda Sampaio-Alves; Luciana Cidade Costa; Catarina Baía; Ana Cláudia Deus; Rita Branquinho; André Marçal; André Tojal; Ahmad Zarour; Ahmad Zarour; Silviu Tiberiu Makkai-Popa; Aurel Mironescu; Florin Grama; Elena Adelina Toma; Ionut Negoi; Daniela Filipescu; Nicolae Bacalbasa; Natalia Motas; Sebastian Ionescu; Octav Ginghina; Radu Costea; Narcis Octavian Zarnescu; Radu Drasovean; Eduard-Alexandru Bonci; Mihail-Gabriel Dimofte; Vlad Porumb; Mikhail Kirov; Yegor Molitvin; Andrey Litvin; Vadim Pykhteev; Marianna Raevskaya; Sergey Efetov; Aleksandr Butyrskii; Mushabab Alshahrani; Azah Althumairi; Nasser Alzerwi; Ahmed Al Ameer; Ahmed Al Ameer; Tariq Madkhali; Abddulrahman Saleh Almulhim; Salman Ghazwani; Abdu Ayoub; Othman Iskander; Mohammed Ghunaim; Mohammed Alharthi; Turki M Alzaidi; Azah Althumairi; Mohammad Alyami; Abdulrahman Al Amri; Azah Althumairi; Abdullah AlFakhri; Amal Alhefdhi; Sharfuddin Chowdhury; Thamer Nouh; Ameen Alshehri; Abdulrahman Alzahrani; Yousef Alalawi; Selmy Awad; Ibrahima Konate; Abdourahmane Ndong; Jacques Tendeng; Nan Zun Teo; Frederick Koh; Jurij Aleš Košir; Uros Bele; Sabra Aqil; Cristina Barrena López; Ana Sánchez Mozo; Antonio Rodriguez Infante; Patricia Caja Vivancos; Mikel Prieto; Igor Alberdi San Roman; Laura Gomez Fernandez; Josep Maria Muñoz Vives; Anna Carreras-Castañer; Berta Díaz-Feijoo; Ramon Sieira-Gil; Victor Turrado-Rodriguez; Anna Sánchez López; Santiago Sánchez-Cabús; 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Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study
No full textPeri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre-operative SARS-CoV-2 diagnosis. Adjusted 30-day mortality in patients without SARS-CoV-2 infection was 1.5% (95%CI 1.4-1.5). In patients with a pre-operative SARS-CoV-2 diagnosis, mortality was increased in patients having surgery within 0-2 weeks, 3-4 weeks and 5-6 weeks of the diagnosis (odds ratio (95%CI) 4.1% (3.3-4.8), 3.9% (2.6-5.1) and 3.6% (2.0-5.2), respectively). Surgery performed >= 7 weeks after SARS-CoV-2 diagnosis was associated with a similar mortality risk to baseline (odds ratio (95%CI) 1.5% (0.9-2.1%)). After a >= 7 week delay in undertaking surgery following SARS-CoV-2 infection, patients with ongoing symptoms had a higher mortality than patients whose symptoms had resolved or who had been asymptomatic (6.0% (95%CI 3.2-8.7) vs. 2.4% (95%CI 1.4-3.4) vs. 1.3% (95%CI 0.6-2.0%), respectively). Where possible, surgery should be delayed for at least 7 weeks following SARS-CoV-2 infection. Patients with ongoing symptoms >= 7 weeks from diagnosis may benefit from further delay
SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study
No full textSARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 days of surgery. SARS-CoV-2 diagnosis was defined as peri-operative (7 days before to 30 days after surgery); recent (1–6 weeks before surgery); previous (≥7 weeks before surgery); or none. Information on prophylaxis regimens or pre-operative anti-coagulation for baseline comorbidities was not available. Postoperative venous thromboembolism rate was 0.5% (666/123,591) in patients without SARS-CoV-2; 2.2% (50/2317) in patients with peri-operative SARS-CoV-2; 1.6% (15/953) in patients with recent SARS-CoV-2; and 1.0% (11/1148) in patients with previous SARS-CoV-2. After adjustment for confounding factors, patients with peri-operative (adjusted odds ratio 1.5 (95%CI 1.1–2.0)) and recent SARS-CoV-2 (1.9 (95%CI 1.2–3.3)) remained at higher risk of venous thromboembolism, with a borderline finding in previous SARS-CoV-2 (1.7 (95%CI 0.9–3.0)). Overall, venous thromboembolism was independently associated with 30-day mortality (5.4 (95%CI 4.3–6.7)). In patients with SARS-CoV-2, mortality without venous thromboembolism was 7.4% (319/4342) and with venous thromboembolism was 40.8% (31/76). Patients undergoing surgery with peri-operative or recent SARS-CoV-2 appear to be at increased risk of postoperative venous thromboembolism compared with patients with no history of SARS-CoV-2 infection. Optimal venous thromboembolism prophylaxis and treatment are unknown in this cohort of patients, and these data should be interpreted accordingly
Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study
No full textPeri‐operative SARS‐CoV‐2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS‐CoV‐2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre‐operative SARS‐CoV‐2 infection were compared with those without previous SARS‐CoV‐2 infection. The primary outcome measure was 30‐day postoperative mortality. Logistic regression models were used to calculate adjusted 30‐day mortality rates stratified by time from diagnosis of SARS‐CoV‐2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre‐operative SARS‐CoV‐2 diagnosis. Adjusted 30‐day mortality in patients without SARS‐CoV‐2 infection was 1.5% (95%CI 1.4–1.5). In patients with a pre‐operative SARS‐CoV‐2 diagnosis, mortality was increased in patients having surgery within 0–2 weeks, 3–4 weeks and 5–6 weeks of the diagnosis (odds ratio (95%CI) 4.1% (3.3–4.8), 3.9% (2.6–5.1) and 3.6% (2.0–5.2), respectively). Surgery performed ≥ 7 weeks after SARS‐CoV‐2 diagnosis was associated with a similar mortality risk to baseline (odds ratio (95%CI) 1.5% (0.9–2.1%)). After a ≥ 7 week delay in undertaking surgery following SARS‐CoV‐2 infection, patients with ongoing symptoms had a higher mortality than patients whose symptoms had resolved or who had been asymptomatic (6.0% (95%CI 3.2–8.7) vs. 2.4% (95%CI 1.4–3.4) vs. 1.3% (95%CI 0.6–2.0%), respectively). Where possible, surgery should be delayed for at least 7 weeks following SARS‐CoV‐2 infection. Patients with ongoing symptoms ≥ 7 weeks from diagnosis may benefit from further delay
