112 research outputs found
Anti-apoptotic Effects of PCP4/PEP19 in Human Breast Cancer Cell Lines: A Novel Oncotarget
博士論文全文, 博士論文要旨Taiji Hamada, Masakazu Souda, Takuya Yoshimura, Shoko Sasaguri, Kazuhito Hatanaka, Takashi Tasaki, Takako Yoshioka, Yasuyo Ohi, Sohsuke Yamada, Masato Tsutsui, Yoshihisa Umekita and Akihide Tanimoto
Anti-apoptotic Effects of PCP4/PEP19 in Human Breast Cancer Cell Lines: A Novel Oncotarget
Oncotarget. 2014; 5(15):6076-6086.
https://doi.org/10.18632/oncotarget.216
ヒト乳癌細胞におけるPCP4/PEP19の抗アポトーシス作用 : 新規の癌標的分子
鹿児島大学博士(医学)Doctor of Philosophy in Medical Science博士論文全文, 博士論文要旨Taiji Hamada, Masakazu Souda, Takuya Yoshimura, Shoko Sasaguri, Kazuhito Hatanaka, Takashi Tasaki, Takako Yoshioka, Yasuyo Ohi, Sohsuke Yamada, Masato Tsutsui, Yoshihisa Umekita and Akihide Tanimoto
Anti-apoptotic Effects of PCP4/PEP19 in Human Breast Cancer Cell Lines: A Novel Oncotarget
Oncotarget. 2014; 5(15):6076-6086.
https://doi.org/10.18632/oncotarget.2161doctoral thesi
Tradition or Cruelty: Following the History of Small Scale Whaling in Taiji, Japan
abstract: Every season from September to March in Taiji, Japan, around 23,000 dolphins, and other small cetaceans are slaughtered or sold to dolphinariums in the name of a 400-year-old tradition. The word ‘tradition’ is often used to rationalize and justify the terrible acts of animal cruelty, as seen in many countries such as bullfighting in Spain, fox hunting in Britain, Thanksgiving in America, and drive hunting in Japan. However, just because something is deemed as a tradition, does not mean it should not be challenged and judged against the standards of morality. Whale and dolphin hunting has stopped becoming a proud cultural tradition of small-scale subsistence whaling and has become a business run on wholesale slaughter and the exploitation of another species. The disconnect between the past and present has led to an evil distortion of the past.
However, this event cannot simply be explained by blaming solely greed and selfishness for driving this long-lasting tradition. By analyzing poems by Misuzu Kaneko, early hunting methods, memorial services, and graves built in the past and comparing them to the current hunting methods, dolphin shows, and the Taiji Whale Museum, one can determine the variety of factors driving these actions and find the point in time when the intentions of these practices shifted. By having a better understanding of the past and the present, one can follow a once-proud tradition becoming a source to justify unethical and cruel behavior. (abstract
Application of doxycycline (DOX)‐combined bone substitute on vertical bone augmentation on rabbit calvaria
Successful treatment of an AIDS patient with prolonged Mycobacterium avium bacteremia, high HIV RNA, HBV infection, Kaposi's sarcoma and cytomegalovirus retinitis
We report an AIDS patient with a high HIV RNA copy number in the plasma who was successfully treated for prolonged Mycobacterium avium bacteremia and other complications.
An HIV-infected patient with high fever, anemia, high alkaline phosphatase, cystic lung lesions, hepatitis B virus infection and Kaposi's sarcoma was referred to our hospital. PCR of the blood revealed Mycobacterium avium bacteremia and the time to blood culture positivity was 8 days. The HIV-1 RNA copy number in the plasma was more than ten million copies/ml and the CD4-positive T cell count was 21 cells/μL.
Although the high fever resolved five days after therapy for Mycobacterium avium was started, the fever recurred just before starting anti-retroviral therapy (ART) including dolutegravir. The patient experienced repeated but self-limiting bouts of severe inflammation. Mycobacteremia was intermittently detected up to 79 days, suggesting that the recurrent episodes of inflammation were due to the intermittent dissemination of mycobacteria, and that persistent treatment is needed.
Five months after the beginning of ART, the HIV-1 RNA copy number in the plasma was still 28,000 copies/ml. An HIV drug-resistance test revealed sensitivity to all anti-retroviral drugs. Eleven months after the initiation of ART, the HIV RNA copy number in the plasma decreased to 45 copies/mL and the CD4-positive T cell count recovered to 205 cells/μL. Our case also suggests that dolutegravir can be effective in cases with prolonged high levels of HIV RNA.
Our findings emphasize that prompt diagnosis and persistent therapy for mycobacterial infection are important for successful treatment.Yoshitaka Furukawa, Heiichiro Hamada, Kazuto Kamikawaji, Taiji Unoki, Hiromasa Inoue, Yukie Tashiro, Mika Okamoto, Masanori Baba, Teruto Hashiguchi
Successful treatment of an AIDS patient with prolonged Mycobacterium avium bacteremia, high HIV RNA, HBV infection, Kaposi's sarcoma and cytomegalovirus retinitis
Journal of Infection and Chemotherapy 26 (2020) 279-281
https://doi.org/10.1016/j.jiac.2019.08.012journal articl
A Transdisciplinary Exposition of Taiji Qigong: Individual Empowerment Through Applied Self-Theraputics: Eireniconic Enablements Towards Optimisation of Mental and Physical Well-being
Self-Therapeutic Adjuvant Modalities (STAM), refers to actions taken by individuals for the benefit of their health and well-being. They are an accepted component of illness prevention, health maintenance, optimisation and or treatment of illness and injury. The potential benefits of applying STAM have not yet been fully realised by Australia's population. Consequently neither has the health infrastructure fully realised the economic benefits which accrue from the wide scale application of STAM, particularly the preventative aspect. Australia's health providers are increasingly stressing the benefits of STAM in their health promotion campaigns. However the fact that almost half the population of NSW is sedentary indicates that education on benefits of STAM as a modality for fostering physical activity still has further to permeate. Evidence strongly suggests that in conjunction with nutrition and hygiene, Moderate-Intensity Activity (MIA) and meditation are of major importance in the physical and mental well-being of people. The author found there is a need for a STAM programme which is suitable for the general population to address their needs for MIA and meditation. Taken into consideration in evaluating research for such a programme were the following parameters: • Efficacy from application for a variety of situations; • Efficiency of use; • Broad based applicability; • Specific relevancy for Australian health needs; and • Economy of implementation. Research and experiment lead the author to conclude that with only slight modification to suit Australian conditions a Traditional Chinese Medical (TCM) programme of Medical and Health Care Qigong (Qubing Yangsheng Gong, QYG) as researched by the Shanghai Institute of Hypertension appeared most suitable for use in Australia. An appropriate term for this programme in Australia was concluded to be Taiji Qigong (TQ). This thesis presents a manual of a program suitable for use by Australians of all ages and levels of fitness
A Comparative Study on ASIC, FPGAs, GPUs and General Purpose Processors in the O(N^2) Gravitational N-body Simulation
In this paper, we describe the implementation of gravitational force calculation for N-body simulations in the context of Astrophysics. It will describe high performance implementations on general purpose processors, GPUs, and FPGAs, and compare them using a number of criteria including speed performance, power efficiency and cost of development. These results show that, for gravitational force calculation and many-body simulations in general, GPUs are very competitive in terms of performance and performance per dollar figures, whereas FPGAs are competitive in terms of performance per Watt figures.2009 NASA/ESA Conference on Adaptive Hardware and Systems (AHS) : San Francisco, CA, USA, 2009.07.29-2009.08.
Japanese educational assistance to developing countries
Today, Japan is the largest foreign aid donor in the world with an annual government expenditure of over ten billion dollars. In its recent development of foreign aid activities, Japan has expanded its educational assistance to developing countries and has steadily increased the number of training programs and centers for technical assistance to developing nations both in Japan and overseas. In addition, the Japanese government also has begun to support the rapidly increasing number of foreign students at Japanese colleges and universities.Although Japan has indicated its willingness to cooperate with educational development of the Third World, the contents of Japanese educational assistance are still relatively unknown to the rest of the world. The purpose of this research is to investigate the nature of Japanese educational assistance to developing nations. In this research, the questions addressed are: What are the most important features of Japanese foreign assistance that are different from those of other donors? What kinds of educational assistance does Japan provide and why? What are the problems of Japan's educational assistance?In conclusion, the author points out the lack of a mature Japanese aid philosophy due to Japan's lack of experience as a foreign aid donor, and recommends development of a clear policy for future activities of Japanese educational assistance and expansion of Japanese educational assistance.Made available in DSpace on 2011-05-07T12:31:26Z (GMT). No. of bitstreams: 2
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