30,624 research outputs found
Erratum to: Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus (Diabetic Medicine, (2006), 23, 9, (974-981), 10.1111/j.1464-5491.2006.01886.x)
No full textIn an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola.In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola
A 2 h periodic variation in the low-mass X-ray binary Ser X-1
No full textSpectroscopy of the low-mass X-ray binary Ser X-1 using the Gran Telescopio Canarias have revealed a ?2 h periodic variability that is present in the three strongest emission lines. We tentatively interpret this variability as due to orbital motion, making it the first indication of the orbital period of Ser X-1. Together with the fact that the emission lines are remarkably narrow, but still resolved, we show that a main-sequence K dwarf together with a canonical 1.4 M? neutron star gives a good description of the system. In this scenario, the most likely place for the emission lines to arise is the accretion disc, instead of a localized region in the binary (such as the irradiated surface or the stream-impact point), and their narrowness is due instead to the low inclination (?10°) of Ser X-1
Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of meson decays to J/ψη and J/ψη′
No full textFirst evidence of the B 0 → J / ψ ω decay is found and the B s 0 → J / ψ η and B s 0 → J / ψ η ′ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb -1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The branching fractions of these decays are measured relative to that of the B 0 → J / ψ ρ 0 decay:frac(B (B 0 → J / ψ ω), B (B 0 → J / ψ ρ 0)) = 0.89 ± 0.19 (stat) - 0.13 + 0.07 (syst),frac(B (B s 0 → J / ψ η), B (B 0 → J / ψ ρ 0)) = 14.0 ± 1.2 (stat) - 1.5 + 1.1 (syst) - 1.0 + 1.1 (frac(f d, f s)),frac(B (B s 0 → J / ψ η ′), B (B 0 → J / ψ ρ 0)) = 12.7 ± 1.1 (stat) - 1.3 + 0.5 (syst) - 0.9 + 1.0 (frac(f d, f s)), where the last uncertainty is due to the knowledge of f d / f s, the ratio of b-quark hadronization factors that accounts for the different production rate of B 0 and B s 0 mesons. The ratio of the branching fractions of B s 0 → J / ψ η ′ and B s 0 → J / ψ η decays is measured to befrac(B (B s 0 → J / ψ η ′), B (B s 0 → J / ψ η)) = 0.90 ± 0.09 (stat) - 0.02 + 0.06 (syst)
Gender-Typical Appearance in Early Childhood: Role of Parental Gender-Typical Appearance and Children’s Gender Similarity
No full textThe emergence of gender-typical appearance in childhood appears to have important implications not only for child and adolescent social-emotional functioning but also for later working life. In the current study, we examined how parents’ gender-typical appearance and children’s gender similarity (to same- and other-gender peers) were related to young children’s gender-typical appearance. We also explored differences in these associations between boys, girls, mothers, and fathers. Home visits were conducted with 74 Dutch two-parent (mother, father) families with both a son and daughter between the ages 3–6 years (96.6% White, 2.0% Asian, 1.4% other ethnicity). The gender-typical appearance of all four family members was assessed by trained and reliable coders in the videotaped observations from the home visits. As a measure of children’s gender similarity, both parents reported on the similarity of their son and daughter to same-gender and other-gender peers. Generalized estimating equations showed that more gender-typical appearance of parents was associated with more gender-typical appearance of girls, but not of boys. No differences were found between mothers and fathers for the association between parent and child appearance. Moreover, children’s gender similarity, evident in parents’ perceived similarity of their child to peers of the same gender and dissimilarity to peers of the other gender, was associated with more gender-typical appearance in children. To conclude, both children’s gender similarity and parents’ gender-typical appearance appear to play a role in the gender-typical appearance of young children
[[alternative]]Bioactivities of Synthetic All-D and All-L Mastoparan M
No full text[[abstract]]Mastoparan M, a tetradecapeptide toxin (INLKAIAALAKKLL-NH2) from the hornet venom, and its D-antipot mastoparan M have been synthesized chemically in this experiment . Under circular dichroism investigation, all D- and L-mastoparan M adopted 28% α-helical structure in the 30% trifluroethanol solution but contained only 10% α-helical structure in the phosphate solution. After addition of mastoparan M to the cultures of tumor cell lines in vitro, D-mastoparan M(12.5 μg/ml) could directly inhibit the growth of tumor cell lines Colo 225 (59%), KB (38%), Hep-2 (63%), H226Br (43%) and HeLa (54%) determined by the MTT assay. We also found that the D-mastoparan M has a higher potency of antitumor cell activity in vitro than L-mastoparan M. Examination under the scanning-beam electron microscope (SEM), the hollow, shrunk, and collapsed structures of tumor cells can be seen after mixed with D-mastoparan M. The appearance of these morphological alterations indicated that the mastoparan M inhibited liability of tumor cells by lysis of target cells directly.
All-D mastoparan M could also cause 3H-thymidine releasing from the labeled bacterial population after mixing for 1 h and completed cell lysis by 4 h. We found that both L- and D- mastoparan M all showed strong activity against both the gram-positive and gram-negative bacteria. Especially, the all-D mastoparan M possesses the highest potency of antibacterial activity about two fold more potent than the L-mastoparan M. The effects of all-D mastoparan M on the surface morphology of Staphylococcus aureus (ATCC 29213) and Escherichia coli (ATCC 25922) were studied by the scanning-beam electron microscope (SEM). We found that small "bleb" extrusions on the surface of some S. aureus and "swelling" on the end site of E. coli after cultured with all-D mastoparan M. This finding indicated the all-D mastoparan M could kill bacteria by disrupting cells directly.
Besides lytic tumor cells and bacteria, mastoparan M could also stimulate immune response. After addition of mastoparan M to the culture of mouse macrophage in vitro, tumor necrosis factor-α (TNF-α) and interleukin 1β (IL-Iβ) were detectable in the culture fluids after 12 h and the highest accumulation were observed at 24 h. Mastoparan M induced an increase in TNF-α secretion and in mRNA level at the same time. The nitrite level, reflecting the nitric oxide synthesis, was also accumulated in the culture of macrophages at 24 h post-mastoparan M addition. In vivo studies showed that mastoparan M induced the formation of TNF-α, IL-1β, and nitrite in the peritoneal exudates of mouse much faster at 90 min, 120 min, and 180 min post-mastoparan M injection respectively. Similarly, significant increases in activity to a high level of myeloperoxidase, a marker for neutrophil and macrophage content, were observed among the peritoneal lavage cells after intraperitoneal injection of mastoparan M. However, induction of nitrite by mastoparan M was completely inhibited by simultaneous addition of anti-mouse TNF-α antibody to the cultures of macrophage. These results suggest that modulation of both neutrophils and macrophages influx by mastoparan M was conveyed through TNF-α and IL-1β secretion accompanied with nitrite formation.
Corrigendum to ‘Eribulin in combination with bevacizumab as second-line treatment for HER2-negative metastatic breast cancer progressing after first-line therapy with paclitaxel and bevacizumab: a multicenter, phase II, single arm trial (GIM11-BERGI)’: (ESMO Open (2021) 6(2), (S2059702921000089), (10.1016/j.esmoop.2021.100054))
No full textThe authors regret that at the time the article was published the following two authors were missing from the author list: R. Caputo and D. Cianniello. Both authors affiliation is the Breast Oncology Department, Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy. The updated author list is as follows: C. De Angelis, D. Bruzzese, A. Bernardo, E. Baldini, L. Leo, A. Fabi, T. Gamucci, P. De Placido, F. Poggio, S. Russo, V. Forestieri, R. Lauria, I. De Santo, R. Caputo, D. Cianniello, A. Michelotti, L. Del Mastro, M. De Laurentiis, M. Giuliano, S. De Placido, G. Arpino. The authors would like to apologise for any inconvenience caused
Light-emission from conjugated dendrimers and polymers
No full textThis thesis reports the photophysical and electroluminescence studies undertaken on two types of material: polymeric and dendritic. The dendritic architecture is a recent concept adopted to develop new materials for light-emitting diodes. The dendritic structure offers a combination of properties of both polymers and small organic molecules whilst having their own interesting characteristic of optimising processibility, charge transport, and optical properties independently. The dendritic structure consists of functional surface groups, conjugated dendrons and a conjugated core. Initial optical (absorption and photoluminescence) studies revealed that the dendrimer emission originates from the core and is independent of excitation wavelength. This was investigated further in distyrylbenzene based dendrimers where the effect of dendrimer generation number on photoluminescence and electroluminescence properties was studied. All dendrimers emit blue electroluminescence with, in some cases, reasonable electroluminescence quantum efficiency in the range of 0.09 % and brightness up to 150 Cd m(^-2). Having established that the furmel effect, where excitation is successfully transferred to the dendrimer core in both PL and EL, different chromophores were incorporated in the dendrimer structure. Colour control was thus demonstrated in EL devices of the different dendrimers, showing the possibility of using a large number of chromophores in a processible form for EL applications. Conjugated polymers were also studied to investigate the nature of the emitting species (poly(p-pyridine)) and the effect of side- chains (poly(p-phenylenevinylene)). In poly(p-pyridine) the emission was found to be strongly dependent on pyridyl ring rotation affecting the emission and its quantum yield while the side-chains in the poly(p-phenylenevinylene) derivatives were found to affect polymer properties such as degree of conversion of non-conjugated to conjugated polymer. The PL quantum yield system was set-up and proved useful in assessing synthesis of new materials
Logarithmic variance profiles and the corresponding f-1 spectra of temperature fluctuations in turbulent Rayleigh-Bénard convection
No full textWe report experimental results for the temperature variance 2(z) and the corresponding frequency spectra P(f) in turbulent Rayleigh-Bénard convection (RBC) in a cylindrical sample of aspect ratioT= D/L = 1:00 (D = 1:12 m is the diameter and L = 1:12 m the height). The measurements were conducted in the Rayleigh-number range 1011 < Ra < 1:35 1014 and Pr ' 0:8. For Ra = 1:35x1014, 2(z) could be described well by a logarithmic dependence on the vertical position z in a range of z 1 < z < z 2 with z 1 ' 70 and z 2 = 0:1L. Here L=(2Nu) is the thickness of a thin thermal sublayer adjacent to the horizontal plate where the heat flux (denoted by the Nusselt number Nu) is carried mostly by thermal diffusion. In the log layer, we found that the temperature spectra had a significant frequency range over which P(f) f with close to 1. As Ra decreased, increased so that the log layer became thinner. At Ra = 2:05 1011, z 2 < z 1 and therefore there was no range for a log layer. Correspondingly, the temperature spectrum near the horizontal plate did not have the f1 scaling form either
Measurement of the branching fractions for B--> D(*)+pi(-)l(-)(nu)over-bar(l) and (B)over-bar(0)-> D-(*)0 pi(+)l(-)(nu)over-bar(l)
No full textWe report on a measurement of the branching fractions for B- --> D(*)+ pi(-)l(-)(nu) over bar (l) and (B) over bar (0) --> D-(*)0 pi(+)l(-)(nu) over bar (l) with 275 x 10(6) B (B) over bar events collected at the Y(4S) resonance with the Belle detector at KEKB. Events are tagged by fully reconstructing one of the B mesons in hadronic modes. We obtain B(B- --> D(+)pi(-)l(-)(nu) over bar (l)) = (0.54 +/- 0.07 (stat) +/- 0.07(syst) +/- 0.06(BR)) x 10(-2), B(B- --> D*+pi(-) l(-) (nu) over bar (l)) (0.67 +/- 0.11 (stat) +/- 0.09(syst) +/- 0.03(BR)) x 10(-2), B((B) over bar (0) --> D(0)pi(+)l(-) (nu) over bar (l)) = (0.33 +/- 0.06(stat) +/- 0.06(syst) +/- 0.03(BR)) x 10(-2), B((B) over bar (0) -->D(*0)pi(+)l(-)(nu) over bar (l)) = (0.65 +/- 0.12(stat) +/- 0.08(syst) +/- 0.05(BR)) x 10(-2), where the third error comes from the error on (B) over bar --> D((*))l(-)(nu) over bar (l) decays. Contributions from B-0 --> D(*+)l(-)(nu) over bar (l) decays are excluded in the measurement of (B) over bar (0) --> D(0)pi(+)l-(nu) over bar (l).Astronomy & AstrophysicsPhysics, Particles & FieldsSCI(E)0ARTICLE5null7
Catalog of 382 weak stars of the zone D. M. + 2° by L. de Ball : F. Folie's report
No full textThe author establishes a report on the L. de Ball’s work on the catalog of 382 weak stars of the zone D. M. + 2°.L’auteur établit un rapport sur un travail de L. de Ball sur le catalogue de 382 étoiles faibles de la zone D. M. +2°
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