249 research outputs found
Physician Preferences in Using Novel Digital Devices for the Management of Atrial Fibrillation-A DAS-CAM III Survey
No full textAim: A recent European Heart Rhythm Association (EHRA) practical guide provides guidance on the use of novel digital devices for heart rhythm analysis using either electrocardiogram (ECG) or photoplethysmography (PPG) technology for the diagnosis of atrial fibrillation (AF). This survey assesses physicians' preferences to use digital devices in patients with possible AF and their impact on clinical decision-making. Methods and Results: Participants of the DAS-CAM III initiated and distributed an online survey assessing physician preferences in using digital devices for the management of AF in different clinical scenarios. A total of 505 physicians (median age: 38 [IQR 33-46] years) from 30 countries completed the survey. A third of respondents were electrophysiologists, the others were cardiologists, cardiology residents, or general practitioners. Electrophysiologists were more likely to have experience with both ECG-based (92% vs. 68%, p < 0.001) and PPG-based (60% vs. 34%, p < 0.001) digital devices. The initial diagnostic approach to each scenario (symptomatic low-risk, symptomatic high-risk, or asymptomatic high-risk patient) was heterogeneous. Electrophysiologists preferred intermittent single-lead ECG monitoring to traditional Holter ECGs to screen for AF. Both electrophysiologists and non-electrophysiologists would rarely use PPG-based devices to diagnose and screen for AF (8.2%-9.8%). Electrophysiologists and non-electrophysiologists use ECG-based technology to confirm PPG-documented tracings suggestive of AF. Conclusion: While PPG-based digital devices are rarely used for diagnosis and screening for AF, intermittent ECG-based digital devices are beginning to be implemented in clinical practice. More education on the potential of novel digital devices is required to achieve diagnostic pathways as suggested by the EHRA practical guide
Cumhuriyet dönemi kağıt paraları : 1927-1969
No full textAnkara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2013.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Zeynep Gül Erel.Erel, Zeynep Gül. HIST 200-18EREL HIST 200-18/4 2012-1
Leadless pacemaker implantation following tricuspid interventions: multicenter collaboration of feasibility and safety
No full textBackgroundPermanent pacing is often required following valve intervention (either surgical or percutaneous); however, tricuspid interventions pose specific challenges to conventional pacing. Therefore, leadless pacemaker (LP) implantation may be the preferred strategy when permanent pacing is required after tricuspid valve intervention.PurposeTo report periprocedural outcomes and follow-up of patients undergoing implantation of a LP system following tricuspid valve interventions.MethodsPatients with previous tricuspid valve intervention at the time of attempted implantation of a LP (MicraTM, Medtronic, Minneapolis, MN, USA) were included.ResultsBetween 2019 and 2022, 40 patients underwent LP implantations following tricuspid interventions in 5 large tertiary centers. The mean age was 68.9 +/- 13.7 years, and 48% patients were male. The indication for pacing was as following: AVB in 27 (68%) patients, AF with slow ventricular response in 10 (25%) patients, and refractory rapid atrial fibrillation (AF) referred to AV junction ablation in 3 (7%) patients. Most of the patients received Micra VR (78%). The procedure was successful in all patients. The mean procedural time is 58 +/- 32 min, and the median fluoroscopy time is 7.5 min. Electrical parameters were within normal range (threshold: 1.35 +/- 1.2 [email protected] ms, impedance: 772 +/- 245 Ohm, R-wave: 6.9 +/- 5.4 mV). No acute complications were observed. During a mean follow-up of 10 months, electrical parameters remained stable, and 4 deaths were occurred (not related to the procedure).ConclusionA LP is a safe and efficient option following tricuspid valve interventions
Author's Reply to "Digital Devices for Arrhythmia Detection: What Is Still Missing?"
No full textLette
Correction: Efficacy of subsequent treatments in patients with hormone-positive advanced breast cancer who had disease progression under CDK 4/6 inhibitor therapy (BMC Cancer, (2023), 23, 1, (136), 10.1186/s12885-023-10609-8)
No full textFollowing publication of the original article [1], the authors reported an error in the author name of Enes Erul. Incorrect: Enes Urul Correct: Enes Erul, The original article [1] has been corrected. © 2023, The Author(s)
Allegory In Hadiths
No full textAteş, Avnullah Enes (Bilecik, Author)Hz. Peygamber (s.a.v.) İslam’ı tebliğinde, içerisinde doğup büyüdüğü Arap toplumunun dil ve edebiyat becerilerini iyi bir şekilde kullanmıştır. Onları hakka davet ederken teşbih, mecaz, kinaye gibi birçok edebi üsluplarla meramını anlatmıştır. Etkili konuşma noktasında sözün büyüleyici bir etkisi olduğunu da yine kendileri dile getirmişlerdir. Bu nedenle Allah Resulünün (s.a.v.) sözlü davet yönünün ve hadislerinin doğru ve iyi anlaşılması o dönemin Arapça dil ve edebiyat yapısının bilinmesiyle mümkündür. Hadislerin bu yönde ele alınarak çalışılması bir zorunluluktur. Hadis şerhlerinde hadislerin edebi yönlerine değinilse de kimi zaman kavram kargaşası yaşanmaktadır. Özellikle kinaye terimi konusunda büyük problemler bulunmaktadır. Ayrıca bütün yönleriyle dağınık bir şekilde ele alınan hadislerin derli toplu ve tek bir meseleye yönelerek incelenmesi daha büyük bir yarar sağlayacaktır. Bundan dolayı bu çalışma, kinayenin şerhlerden tespitindeki bu problemi ele alacak, sonra da Allah Resulünün (s.a.v.) kinayeli kullanımlarına değinecektir
Course of unborn baby's heart by wireless baby tracking system
No full textKaplanoglu, Mustafa/0000-0002-4658-1336; Isiker, Hakan/0000-0002-6465-8480; Yigit, Enes/0000-0002-0960-5335;The most important problem for pregnant and gynecologist is tracking of unborn baby. An important part of infant deaths occur in the last months of pregnancy. For this reason, by using an external fetal monitor non-stress test (NST) measurements are done for gathering information about the baby's condition. This method is a procedure that requires specialist from a medical center. The proposed study aims wirelessly transmission of NST measurement results to the specialist or health center. Thus, in case of any particular problems by giving notice to the patient, it is intended to provide her being shipped to the nearest medical facility. © 2013 The Chamber of Turkish Electrical Engineers-Bursa. © 2020 Elsevier B.V., All rights reserved
An enyne cycloisomerization/[5+1] reaction sequence to synthesize tetrahydroisoquinolinones from enyne-enes and CO
No full textAn enyne cycloisomerization/[5+1] reaction sequence was developed to synthesize tetrahydroisoquinolinones from linear enyne-enes and CO. The first step is a gold(I)-catalyzed enyne cycloisomerization, generating six-membered- ring-fused vinylcyclopropanes. The second step is a rhodium(I)catalyzed [5+1] reaction of vinylcyclopropanes with CO. This two-step reaction could also be carried out in one-pot without isolating the cycloisomerization product generated from the first step of this sequence.Natural Science Foundation of China [21472005]SCI(E)ARTICLE132158-21615
Dolusavak ve enerji kırıcı yapı tip seçiminin uzman sistemler ile belirlenmesi / Type selection of spillway and energy dissipator structure using expert systems
No full textEvaluation of the relationship between fibromyalgia syndrome and subclinical atherosclerosis
No full textTıp Fakültesi, Radyoloji Ana Bilim DalıFibromyalji Sendromu (FMS) yaygın vücut ag?rısı, spesifik anatomik bölgelerde artmıs? hassasiyet ve yorgunluk, irritabl barsak sendromu, uyku bozuklug?u gibi klinik durumların es?lik ettig?i kronik bir kas-iskelet sistemi hastalıg?ıdır. FMS osteoartritten sonra en sık gözlenen romatizmal hastalıktır. Kullanılan tanı kriterlerine göre prevalansı %2-8 arasında deg?is?mektedir. FMS'nin etyolojisi bilinmemekte ve patofizyolojisi tam olarak açıklanamamaktadır. Dünya genelindeki ölüm sebebleri arasında, koroner arter hastalıg?ı ve iskemik serebrovasküler hastalıklar en önde gelen yerlerini korumaktadırlar. Bu iki hastalıg?ın ortak etyopatogenezinde yer alan subklinik aterosklerozu tespit etmek önemlidir. Ateroskleroz, damar duvarının intima ve mediya tabakalarını tutan ilerleyici olan damar lümenini daraltan multifaktöriyel bir hastalıktır. Gelecekteki vasküler olayların güçlü bir belirleyicisi olan karotis intima media kalınlıg?ı (KİMK) erken dönem aterosklerozu saptamak için kullanılır. Fibromyalji sendromu ile ateroskleroz arasında ilis?ki olabileceg?i önceki çalıs?malarda gösterilmis?tir. Bu çalıs?mada Fibromyalji Sendromu ile subklinik ateroskleroz arasındaki ilis?ki deg?erlendirilmis?tir. Bu çalıs?ma FMS hastaları ile sag?lıklı gönüllülerin kars?ılas?tırıldıg?ı tek merkezli prospektif bir çalıs?madır. Ocak 2020 ve Nisan 2020 arasında, Sivas Cumhuriyet Üniversitesi Tıp Fakültesi Hastanesi'nde aterosklerotik risk faktörü olmayan 20 FMS hastası ve 20 gönüllü çalıs?maya dahil edildi. Tüm katılımcıların ayrıntılı öykü ve laboratuar sonuçları kaydedildi ve B-mod ultrasonografi ile karotis intima media kalınlıkları ölçüldü. Hasta grubu semptom sürelerine göre ( ? 5 yıl, > 5 yıl) ikiye ayrıldı. Semptom süresi 5 yıl ve altında olan grupta 9 hasta, 5 yıldan fazla olan grupta 11 hasta vardı. Hasta ve kontrol grubunun yas? ve vücut kitle indeksi ile kreatinin dıs?ındaki laboratuvar deg?erleri kars?ılas?tırıldıg?ında istatistiki açıdan benzerdi. Kreatinin deg?eri farklı olmakla birlite iki grupta da normal aralıktaydı. Sag? ana karotis arter intima media kalınlıg?ı (RKİMK) ortalaması hasta grubunda 0,5 (±0,07) mm, kontrol grubunda 0,43 (±0,05) mm; sol ana karotis arter intima media kalınlıg?ı (LKİMK) ortalaması hasta grubunda 0,5 (±0,06) mm, kontrol grubunda 0,43 (±0,05) mm bulunmus? olup hasta grubunda anlamlı yüksek oldug?u görülmüs?tür. Ayrıca ortalama karotis intima media kalınlıg?ı (OKİMK) hasta grubunda 0,52 (±0,05) mm, kontrol grubunda 0,43 (±0,03) olarak bulunmus? olup hasta grubunda anlamlı yüksektir. Hasta grubun subgrup analizinde yas? dıs?ındaki temel karakteristik özellikler ve RKİMK-LKİMK-OKİMK deg?erleri her iki grupta benzerdi. Çalıs?mamızda önceki çalıs?maları destekler nitelikte Fibromyalji hastalarında KİMK'nın arttıg?ı gösterilmis?tir. Bu çalıs?mada farklı olarak hastalar semptom süresine göre kars?ılas?tırılmıs? olup aralarında KİMK'ı açısından anlamlı fark olmadıg?ı görülmüs?tür. Sonuçta FMS enflamatuvar bir hastalık olmamasına rag?men KİMK'da artıs?a neden olmaktadır ve endotel disfonksiyonuna neden olabileceg?i düs?ünülmektedir. Anahtar kelimeler: Fibromyalji Sendromu, subklinik ateroskleroz, karotis intima media kalınlıg?ıFibromyalgia Syndrome (FMS) is a chronic condition causing pain, stiffness, and tenderness of the muscles, tendons, and joints. It is also characterized by restless sleep, tiredness, fatigue, anxiety, depression, and disturbances in bowel functions. FMS is the most common rheumatic disease after osteoarthritis. Its prevalence is between 2-8% according to the diagnostic criteria. The etiology of FMS is still unclear and its pathophysiology has not been fully explained yet. Coronary artery disease and ischemic cerebrovascular diseases are the number one cause of death globally. It is important to identify subclinical atherosclerosis in the common etiopathogenesis of these two diseases. Atherosclerosis is the multifactorial inflammatory disease of the vasculature that affects large- and medium-sized arterial vessels. It is related to spesifically the intima and media layers of the vascular wall. The Carotid Intima Media Thickness (CIMT) is a valid marker of early atherosclerosis and thus, it has the potential to detect cardiovascular disease in its subclinical phase. In the literature there are studies about the relationship between fibromyalgia and atherosclerosis. In this study, the relationship between Fibromyalgia Syndrome and subclinical atherosclerosis were evaluated. This study is a single-center prospective study comparing FMS patients with healthy volunteers. Between January 2020 and April 2020, 20 FMS patients and 20 volunteers who were not atherosclerotic risk factors were included in the study at Sivas Cumhuriyet University Hospital. Details of history and laboratory test results of all participants were recorded. The carotid intima media thicknesses were measured by B-mode ultrasonography. The patient group was divided into two according to the duration of the symptoms as ? 5 years and > 5 years. There were 9 patients in the group with a symptom duration of 5 years and less, and 11 patients in the group with more than 5 years. When the age and body mass index and the laboratory values other than creatinine were compared in the patient and control groups, there were no statistically significant. Although the creatinine value was different, it was in the normal range in both groups. Mean right carotid artery intima media thickness (RCIMT) was 0.5 (± 0.07) mm in the patient group, 0.43 (± 0.05) mm in the control group; mean left carotid artery intima media thickness (LCIMT) was 0.5 (± 0.06) mm in the patient group, 0.43 (± 0.05) mm in the control group. It was significantly high in the patient group compared to control group. In addition, the mean carotid intima media thickness (MCIMT) was 0.52 (± 0.05) mm in the patient group and 0.43 (± 0.03) in the control group. It was also significantly high in the patient group compared to control. In the subgroup analysis of the patient group, the main characteristic features and the values of RCIMT-LCIMT-OCIMT were similar in both groups except for patients age. Similar to previous studies, in our study, it has been shown that CIMT increases in patients with Fibromyalgia. On the other hand, according to the duration of the symptom, there were no significant difference between patients in terms of CIMT. As a result, although FMS is not an inflammatory disease, it causes an increase in CIMT and endothelial dysfunction. Keywords: Fibromyalgia Syndrome, subclinic atherosclerosis, carotid intima media thicknes
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