311 research outputs found

    Asse 4 – Capacità amministrativa, priorità di investimento: 11.ii.

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    Il Rapporto raccoglie i risultati del progetto “Supporto alle attività di coordinamento inter istituzionale e tra programmi operativi sui temi della disabilità”, Asse 4 – Capacità amministrativa, priorità di investimento: 11.ii. Il file del Rapporto è sotto embargo in quanto presso l'Autorità di gestione.Unione europea - Fondo sociale europeo PON Inclusione Ministero del lavoroil rapporto raccoglie i risultati del progetto “supporto alle attività di coordinamento inter istituzionale e tra programmi operativi sui temi della disabilità”, asse 4 – capacità amministrativa, priorità di investimento: 11.ii. il file del rapporto è sotto embargo in quanto presso l'autorità di gestione. supporto alle attività di coordinamento inter istituzionale e tra programmi operativi sui temi della disabilità lucia chiurco raffaella franceschelli francesca taricon

    Correction to: Size‐Dependent Enforcement, Tax Evasion and Dimensional Trap

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    The article “Size‐Dependent Enforcement, Tax Evasion and Dimensional Trap”, written by Raffaella Coppier, Elisabetta Michetti and Luisa Scaccia, was originally published electronically on the publisher’s internet portal on 05 July 2023 without open access. With the author(s)’ decision to opt for Open Choice the copyright of the article changed on 24 February 2024 to © The Author(s) 2024 and the article is forthwith distributed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made

    Simvastatin Reduces Doxorubicin-Induced Cardiotoxicity: Effects beyond Its Antioxidant Activity

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    This study aimed to evaluate if Simvastatin can reduce, and/or prevent, Doxorubicin (Doxo)-induced cardiotoxicity. H9c2 cells were treated with Simvastatin (10 µM) for 4 h and then Doxo (1 µM) was added, and the effects on oxidative stress, calcium homeostasis, and apoptosis were evaluated after 20 h. Furthermore, we evaluated the effects of Simvastatin and Doxo co-treatment on Connexin 43 (Cx43) expression and localization, since this transmembrane protein forming gap junctions is widely involved in cardioprotection. Cytofluorimetric analysis showed that Simvastatin co-treatment significantly reduced Doxo-induced cytosolic and mitochondrial ROS overproduction, apoptosis, and cytochrome c release. Spectrofluorimetric analysis performed by means of Fura2 showed that Simvastatin co-treatment reduced calcium levels stored in mitochondria and restored cytosolic calcium storage. Western blot, immunofluorescence, and cytofluorimetric analyses showed that Simvastatin co-treatment significantly reduced Doxo-induced mitochondrial Cx43 over-expression and significantly increased the membrane levels of Cx43 phosphorylated on Ser368. We hypothesized that the reduced expression of mitochondrial Cx43 could justify the reduced levels of calcium stored in mitochondria and the consequent induction of apoptosis observed in Simvastatin co-treated cells. Moreover, the increased membrane levels of Cx43 phosphorylated on Ser368, which is responsible for the closed conformational state of the gap junction, let us to hypothesize that Simvastatin leads to cell-to-cell communication interruption to block the propagation of Doxo-induced harmful stimuli. Based on these results, we can conclude that Simvastatin could be a good adjuvant in Doxo anticancer therapy. Indeed, we confirmed its antioxidant and antiapoptotic activity, and, above all, we highlighted that Simvastatin interferes with expression and cellular localization of Cx43 that is widely involved in cardioprotection

    A spatial cross-sectional analysis of political trends in Italian municipalities

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    The aim of this paper is to detect mimicking behaviour in the tax setting of local governments which share similar political ideology. We conduct an empirical investigation of municipalities' cross-sectional data of the Marche region using spatial econometrics models. Discriminating between several sources of fiscal interaction, empirical evidence suggests that municipalities governed by the same coalition tend to implement similar tax rates according to their ideology. Copyright (c) 2008 the author(s). Journal compilation (c) 2008 RSAI.

    Pendenza anomala di processi arbitrali ed estinzione del processo per inattività delle parti

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    The Author analyes two italian judgments concerning both arbitral proceedings pending for a long time without any activit

    “Noi abbiamo visto tante città, abbiamo un’altra cultura”. Servizio domestico, migrazioni e identità di genere in Italia: uno sguardo di lungo periodo

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    Abstract The article aims to show both long-term continuities and the transformation of domestic service in Italy during the 19th and 20th century. Firstly, the article shows that, today, domestic workers are possibly more numerous than a century ago, and it explains why Italian families seek private solutions (such as hiring a domestic worker) to the problem of reconciling reproductive and productive labour. The gap between "rich" and "poor" countries as well as Italian migration policy make this choice possible, because they make working in Italy as a domestic worker "attractive" for many migrants and employing a foreigner advantageous for Italian families. A further consequence is that there are a considerable number of men among migrant domestic workers: their arrival has contributed to a certain "re-masculinisation" of domestic personnel. The reasons for the feminisation of domestic service in the 19th and 20th centuries are analysed in the second and third section of the paper, where the author also considers the policies developed by servants' associations, the Catholic church and the Italian state. The author investigates the role of demographic and economic factors in stimulating migration and then focuses on two cases characterised by a growing imbalance between rural and urban areas, i.e., the province of Bologna in the 19th century and Italy during the fascist era. The author concludes by noting that domestic service (paradoxically) represented a way for many women to escape misery and become more independent

    Delegitimization and US presidential electoral campaigns, 1896-1980

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    The essay focuses on delegitimization of one’s political opponent as a discursive strategy in US political elections from 1896 to 1980. Starting with a definition of delegitimization as a means of contesting the legitimacy of the opponent’s aspiration to power by turning him/her into an enemy outside the constitutional perimeter, the author highlights the circumstances that conduced to political delegitimization tactics in US presidential campaigns, as well as the stock themes in use over the various periods

    Cooperare nella scuola per costruire comunità. Dimensioni organizzative e culturali, metodologie e strategie operative

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    This PhD thesis intends to clear whether and on what conditions a "community school " is possible nowadays. In the firsts chapter we mainly tried to reconsider and re-define the Community construct, remarking an often overworked use and a polisemantic nature and ambiguity of this word, mainly used as a metaphor than as an analytical concept, due to its various meanings and its ambiguity . In particular we tried to recover the analysis which, beginning from the end of the 19 th century, was made by some sociologists, to continue up to our time with the present-day debates, which have seen opposition between the liberals and the communitarians positions, especially in the Anglo-Saxon world. While some late eighteenth century have thought of the Community as a stage in the process of the social change showing dominations of the society on the Community, highlighting an evolution of the dicothomes coyle other authors, mainly in more recent times, have pointed out an inherent tendency of the two ideal types to coexist and mix, thinking that the coexistence of community life next to forms of society life is possible. In the second chapter we tried to underline the educational value of the Community, pointing out, in particular, that the Community value is achieved in educational particularity when the community acts knowingly and intentionally in the training of persons living inside it. First we tried to outline the attempts made in Italy to create an authentic Community school, from the delegates decrees (after the 1968 crisis and the Faure Report) to the school of autonomy of our times (2000). Then, in order to realize a comparison on an international ground, we examined in USA in particular to the experiences of Community school followed and documented by Thomas Sergiovanni, in San Antonio (Texas), in collaboration with the Trinity University. Those experiences, and even more the above-mentioned author, have become the main reference of our study, both from point of view of a the theoretic reflection and from an operating point of view . In the third chapter we pointed out the pedagogical, methodological and educational choices which are the most consistent with the model and the more suitable for the development of the organizing and cultural dimensions according to which a community school may be declined. A special attention has been paid to the cooperative methods that we considered particularly consistent for organisation in the school activity, in students groups and teachers groups. In the last chapter we described the experience held with the Childhood Centres of the Cooperative "Insieme Si Può" connected to Foundation "Ispirazione", promoter and supporter of the project. In particular, the aim of the intervention (developed according to the action research approach) was to test some operative instruments to verify, even if empirically, the functionality in order to promote the dimensions according to which the community school is organized. Being aware to undertake a path that couldn’t bring to definite goal, that is to the creation of an authentic community school, we went on considering that goal as an ideal rule toward which to go with which to compare the reality. As regards that goal we tried to give a little contribution to the study of the of the necessary features for a possible project hypothesis.La presente tesi di dottorato si è proposta di chiarire se e a quali condizioni è possibile oggi una “scuola comunità”. Nel primo capitolo si cerca di fare chiarezza attorno al costrutto di comunità rilevando, a tal proposito, un uso spesso inflazionato e una polisemanticità e ambiguità del termine, spesso usato più come metafora che come concetto analitico. In particolare si è cercato di recuperare l’analisi che, a partire dalla fine del diciannovesimo secolo, è stata realizzata da alcuni sociologi, per proseguire fino ai giorni nostri con i dibattiti contemporanei che hanno visto contrapporsi fra loro le posizioni, soprattutto nel mondo anglosassone, dei liberals e dei communitarians. Se alcuni autori di fine Ottocento hanno pensato alla comunità come ad una tappa del processo di social change che vede l’affermarsi della società sulla comunità evidenziando un carattere evolutivo della coppia dicotomica, altri, soprattutto in tempi più recenti, hanno evidenziato una tendenza intrinseca dei due ideal tipi a coesistere e mescolarsi, ritenendo possibile la coesistenza di vita comunitaria accanto a forme di vita societaria. Nel secondo capitolo si è tentato di cogliere la valenza pedagogica della comunità, rilevando, in particolare, che il valore comunitario si realizza nella sua peculiarità educativa quando la comunità agisce consapevolmente e intenzionalmente per la formazione delle persone che in essa vivono. Da una parte si è cercato di delineare i tentativi, fatti in Italia, dai Decreti Delegati (dopo la crisi del ’68 e il Rapporto Faure) alla scuola dell’autonomia dei giorni nostri (2000), per la creazione di una comunità scolastica autentica. Dall’altra, allo scopo di realizzare un confronto sul piano internazionale, si è guardato agli Stati Uniti e in particolare alle esperienze di community school seguite e documentate da Thomas Sergiovanni, a San Antonio in Texas in collaborazione con la Trinity University. Tali esperienze, e più ancora tale autore, sono divenuti il riferimento principale del percorso, sia dal punto di vista della riflessione teorica che dal punto di vista operativo. Nel terzo capitolo sono state messe in rilievo le scelte pedagogiche, metodologiche e didattiche più coerenti con il modello e più adatte allo sviluppo delle dimensioni organizzative e culturali, in cui una scuola comunità può essere declinata. Un particolare approfondimento è stato fatto all’interno del capitolo in merito ai metodi cooperativi ritenuti particolarmente coerenti per l’organizzazione dell’attività in classe e nella scuola, nei gruppi studenti e nei gruppi docenti. Nell’ultimo capitolo si è descritto l’intervento sul campo che è stato realizzato con i Centri Infanzia della Cooperativa “Insieme Si Può” ,collegata a Fondazione “Ispirazione”, ente promotore e sostenitore del progetto. In particolare, l’obiettivo dell’intervento (sviluppato secondo la metodologia della ricerca azione action research) è stato quello di testare alcuni strumenti operativi per verificarne, anche se in modo empirico, la funzionalità ai fini della promozione delle dimensioni in cui la scuola comunità si declina. Nella consapevolezza di intraprendere un percorso che non poteva portare ad una meta definitiva, e cioè alla creazione di un’autentica scuola comunità si è proceduto considerando tale meta come un ideale regolativo verso cui muovere e con cui comparare la realtà. Rispetto a questa meta si è cercato di dare un piccolo contributo per lo studio delle caratteristiche necessarie ad una possibile ipotesi progettuale

    ‘I am the means and not the end’: Dante and E.M. Forster

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    The well-known epigraph to Howards End (1910), “only connect”, provides a fitting motto for the life and work of Edward Morgan Forster. With the epigrammatic intensity of a manifesto, the famous locution also encapsulates the compositional principle of Forster’s art, informed by intertextual references and quotations, ranging from Pope to Whitman, from Plato to Shakespeare, from Shelley to Dante. Less explicit than that of other models, the presence of the Sommo Poeta permeates Forster’s fictional as well as critical universe like a basso continuo, to use one of the musical metaphors so dear to the English writer: while Dante’s spirit can be caught in the literary interstices in which the narration aspires to become vision – in his early novels and most notably in Forster’s fictional representation of Dante in the supernatural tale “A Celestial Omnibus” (1911) –, the Italian poet features as a privileged interlocutor in Forster’s criticism and journals. This essay intends to retrace the forms and development of this artistic dialogue starting from the lecture on Dante that Forster delivered in 1907 for the Working Men’s College, the result of a study of the Florentine poet and of The Divine Comedy over which, as the author wrote in 1958, he had “put in quite a lot of work”

    Parodic Brachylogy and Semantic Density in Edward Lear’s ‘Volcanic’ Italian Limericks

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    Edward Lear can be considered as one of the most versatile artists of the Victorian Age: he started his career as a natural illustrator (he worked with John Gould, the most famous Victorian ornithologist) and travel writer and, although he aspired all his life to make his name as a landscape painter, he became known as a nonsense poet, as the author of the popular A Book of Nonsense (1846). My paper aims to show Lear as a “brachylogical writer” and examine some of his Italian limericks in light of a brief discussion of the main features of nonsense as a genre and of its ‘parodic’ quality
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