63,157 research outputs found
Einführung in das Studium der Geschichte, von Dr. Wilhelm Bauer. Tübingen, J.-C.-B Mohr (P. Sicbeck), 1921.
No full textFournier Pierre-François. Einführung in das Studium der Geschichte, von Dr. Wilhelm Bauer. Tübingen, J.-C.-B Mohr (P. Sicbeck), 1921.. In: Bibliothèque de l'école des chartes. 1923, tome 84. pp. 355-356
R. Rodière et C. Fournier, La faillite dans la jurisprudence
No full textR. Rodière et C. Fournier, La faillite dans la jurisprudence. In: Revue internationale de droit comparé. Vol. 27 N°3, Juillet-septembre 1975. p. 765
Validation of the Fournier\u27s gangrene severity index in a large contemporary series.
No full textPURPOSE: In this study we identified prognostic factors for survival and validated the accuracy of the Fournier\u27s gangrene severity index in patients with Fournier\u27s gangrene.
MATERIALS AND METHODS: We retrospectively reviewed medical records of patients diagnosed with Fournier\u27s gangrene between 1996 and 2006. Fournier\u27s gangrene severity index scores were assessed using a receiver operating characteristic curve. Using an outcome variable of inpatient mortality, univariate analyses were performed using the Mann-Whitney U, chi-square and Fisher exact tests.
RESULTS: A total of 68 patients (79.4% male, mean age 55.8 +/- 15.2 years) diagnosed with Fournier\u27s gangrene met the criteria for review. The inpatient mortality rate was 10% (7 patients). The mean Fournier\u27s gangrene severity index score for survivors was 5.4 +/- 3.5 vs 10.9 +/- 4.7 for nonsurvivors (p = 0.006). Isolated Fournier\u27s gangrene severity index and individual laboratory parameters associated with mortality included heart rate (p = 0.05), respiratory rate (p = 0.02), serum creatinine (p = 0.03), serum bicarbonate (p = 0.001), serum lactate (p = 0.001) and serum calcium (p = 0.03). Although mean total body surface area was only suggestive of an association (p = 0.169), abdominal wall (p = 0.004) or lower extremity (p = 0.005) involvement was associated with increased mortality. Using a Fournier\u27s gangrene severity index score threshold of 9 (sensitivity 71.4%, specificity 90%) there was a 96% survival rate in patients with a Fournier\u27s gangrene severity index of less than 9 and a 46% mortality rate in those with a Fournier\u27s gangrene severity index of 9 or greater (p = 0.001, OR 22, 95% CI 3.5-139.7).
CONCLUSIONS: The Fournier\u27s gangrene severity index remains an objective and simple method to quantify the extent of metabolic aberration at presentation in patients with Fournier\u27s gangrene. A Fournier\u27s gangrene severity index threshold value of 9 is sensitive and specific for predicting mortality in this patient population
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
No full textThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
Impact of Climate Change on the Santos Harbor, Sao Paulo State (Brazil)
No full textSantos Harbor Area (SHA) in Sao Paulo Coastline (Brazil) is the most important marine cargo transfer terminal in the Southern Hemisphere. A long term relative tidal level variability assessment shows a consistent response to relative sea level rise. A wave data base Wave Watch III was compared with a long term wave data‐base generated by the ERA40‐ECMWF (2003), both local validated. The current bed level of SHA
Outer Channel is ‐15.00 m (Chart Datum or, in abbreviation, CD), maintained by dredging. According to the cargo throughput forecast, in 2025, the Access Channel will have to be deepened to level of ‐17.00 m. The feasibility of that choice is discussed from a technical, economical and conceptual navigation point of view in that context. A data set found from a scale model of the whole area of Santos Bay, Estuary and nearby beaches,
showed the impact of maritime climate changes upon the coastal area. In the previous researches developed by the authors, it was demonstrated that the wave climate, the tides and tidal currents affect harbor and coastal structures maintenance, beaches stability, tidal inlet, sediment transport, saline intrusion and wetlands.
Considering the increasing of the sea hazards and the high values of the infrastructures in that coastline, it is necessary to mitigate the risks. Hence, based on the results obtained by the authors, are highlighted guidelines strategies suggested for Access Channels dimensions, wharves free‐board, jetties dimensions, dredging rates, rigid and flexible littoral defenses and land protection against flooding (including wetlands)
Supplemental Material for Kumar, Fournier, and Stirling, 2022
No full textMost recent version of the Supplementary Tables for the article entitled "Integrative analysis and prediction of human R-loop binding proteins".
Supplementary figures for the manuscript titled "Integrative analysis and prediction of human R-loop binding proteins" by Kumar*, Fournier* and Stirling currently under review.</p
Contribution of flows around active regions to the north-south helioseismic travel-time measurements
No full textContext. In local helioseismology, the travel times of acoustic waves propagating in opposite directions along the same meridian inform us about horizontal flows in the north-south direction. The longitudinal averages of the north-south helioseismic travel-time shifts vary with the sunspot cycle.
Aims. We aim to study the contribution of inflows into solar active regions to this solar-cycle variation.
Methods. To do so, we identified the local flows around active regions in the horizontal flow maps obtained from correlation tracking of granulation in continuum images of the Helioseismic and Magnetic Imager onboard the Solar Dynamics Observatory. We computed the forward-modeled travel-time perturbations caused by these inflows using 3D sensitivity kernels. In order to compare with the observations, we averaged these forward-modeled travel-time perturbations over longitude and time in the same way as the measured travel times.
Results. The forward-modeling approach shows that the inflows associated with active regions may account for only a fraction of the solar-cycle variations in the north-south travel-time measurements.
Conclusions. The travel-time perturbations caused by the large-scale inflows surrounding the active regions do not explain in full the solar-cycle variations seen in the helioseismic measurements of the meridional circulation
Fire-scars and polymodal age-structure provide evidence of fire-events in an Aleppo pine population in southern France
No full textAleppo pine (Pinus halepensis Mill.) is adapted to fire, the most important disturbance in Mediterranean ecosystems. This species is known to be sensitive to fire and is usually killed when burned, but has a powerful regenerative capacity following burning. Sometimes, however, pines survive within burned areas, suggesting a certain potential for recording fire events in terms of age-structure and eventually scars. In the present study, fire scars on Aleppo pine trunks were used to construct a 150-year fire record in a burned forest in southern France. Four fires were detected with a mean fire return interval of 27 years: minimum 13 years and maximum 45 years. The age structure of the Aleppo pine population was analyzed on the basis of dated fire-scars in order to test the role of fire in creating the polymodal structure of the pine population. Results show the presence of multiple "cohorts" (subpopulations) of Aleppo pine. There appear to have been several pulses of tree recruitment, with the two largest cohorts corresponding to regeneration after the 1919 and 2000 fires. Other fires were recognized based on fire scars but these were not associated with obvious post-fire pine recruitment. Regeneration success is likely to depend on fire severity and on the length of fire-free intervals. Fire history and associated age-structure can thus be reconstructed using Aleppo pine stands. © 2013 Elsevier GmbH
Fournier’s Gangrene Mortality Index (FGMI): A New Scoring System for Predicting Fournier’s Gangrene Mortality
No full textObjectives: Fournier’s gangrene is an aggressive, rapidly progressing, and life-threatening necrotizing fasciitis of the perineal and genital regions. Various scoring systems have been developed for predicting survival and prognosis in Fournier’s gangrene. This retrospective study aimed to evaluate the effectiveness of the newly developed Fournier’s gangrene mortality index (FGMI) in predicting mortality associated with Fournier’s gangrene. Methods: The study included patients over the age of 18 years who were followed-up with a diagnosis of Fournier’s gangrene in the general surgery clinics of three different hospitals in Şanlıurfa province between 2014 and 2024. The patients included in this study were divided into two groups: deceased (n = 20) and surviving (n = 149). In FGMI, the parameters used were age, creatinine level, albumin level, lymphocyte percentage, and neutrophil-to-lymphocyte ratio. Based on the total score and risk assessment, <5 points were categorized as low-to-moderate mortality risk and ≥5 points as high mortality risk. Results: A total of 169 patients with a diagnosis of Fournier’s gangrene were included in the study; 87 were men (51.48%). The median age of all patients was 53 (40–63) years; 20 patients (11.8%) died. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score did not show a statistically significant difference between the deceased and surviving groups (p = 0.5). Compared to the survivors, the deceased had higher neutrophil counts, neutrophil percentages, neutrophil-to-lymphocyte ratios, platelet-to-lymphocyte ratios, and C-reactive protein-to-albumin ratios, whereas lymphocyte counts, lymphocyte percentages, eosinophil counts, eosinophil percentages, monocyte counts, and monocyte percentages were lower, and these differences were statistically significant. According to receiver operating characteristic (ROC) analysis, the ROC-area under the curve for predicting mortality based on an FGMI score of ≥5 was 0.88 (95% CI: 0.80–0.95) with a sensitivity of 90% and a specificity of 70% (p < 0.001). Univariate risk analysis was performed, and the odds ratio revealed that mortality risk in patients followed-up for Fournier’s gangrene with a FGMI score of ≥5 was 20 times higher (4.48–90.91) (p < 0.001). Conclusions: The results reveal that the FGMI score is a scoring system that can predict mortality at the initial clinical presentation of patients with Fournier’s gangrene. Another important finding of the present study is that the LRINEC score was not sufficiently effective in predicting mortality
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
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