1,190 research outputs found
The 85th Anniversary of Academician V.V. Alekseev
No full textIn the article dedicated to the 85th anniversary of Doctor of Historical Sciences, Professor and Academician of the Russian Academy of Sciences Veniamin V. Alekseev, the author traces the main milestones of the scientific biography of the prominent historian who is a well-known specialist in the field of national history and the theory of historical process and the founder of the Institute of History and Archaeology of the Ural Branch of the Russian Academy of Sciences. The paper considers the main stages of the formation of the scientist, his scientific, organizational and administrative activities in the field of historical science. The author highlights the scientific results of Academician V.V. Alekseev that made him well known in Russia and abroad, his theoretical and methodological studies and such large blocks of scientific research as the history of Russian modernizations, the phenomenon of Russian regionalism, the history of metallurgy of the Urals and industrial heritage. The article also focuses on the features of the scientific method of V.V. Alekseev and his merits in the formation of the documentary base for historical research
The game space and its attributive characteristic in the novel "The defence" by V.V. Nabokov
No full text© Journal of Language and Literature. The article deals with the analysis of game space and its attributive characteristic in the novel "The Defence" by V.V. Nabokov. The author provides a review of the most interesting and significant works, devoted to the study of game phenomenon in the creative work by V.V. Nabokov. Besides, the meaning of notion "game text" is expanded in the work; there are also made the conclusions about lexical organization of the novel game space (it is a chessboard in this case) and about ways of characterization of this space: 1) direct characterization (through description); 2) indirect characterization (through the comparison with another subject)
The game space and its attributive characteristic in the novel "The defence" by V.V. Nabokov
No full text© Journal of Language and Literature. The article deals with the analysis of game space and its attributive characteristic in the novel "The Defence" by V.V. Nabokov. The author provides a review of the most interesting and significant works, devoted to the study of game phenomenon in the creative work by V.V. Nabokov. Besides, the meaning of notion "game text" is expanded in the work; there are also made the conclusions about lexical organization of the novel game space (it is a chessboard in this case) and about ways of characterization of this space: 1) direct characterization (through description); 2) indirect characterization (through the comparison with another subject)
Trips Of The Orientalist V.V. Barthold To Bukhara And Their Scientific Significance
No full textThis article discusses the trips of Academician V.V. Barthold to Bukhara to get acquainted with medieval monuments of writing, as well as scientific expeditions of Russian orientalists in the late 19th– early 20th centuries. The author analyzes the scientist's attitude to the issue of studying the history of Bukhar
A personality as the focal point of the weltanschauung exploration by V.V. Zen'kovs'ky
No full textУ
статті
показано ключову роль поняття і принципу особистості у становленні та розвиткові системи поглядів В. В. Зенъковського.In the article the author expounds upon the key role of the concept and principle of the personality in the establishment and the development of V.V. Zen 'kovs 'ky 's system of standpoints
Role of renin-angiotensin-aldosterone system in the interaction with coronavirus SARS-CoV-2 and in the development of strategies for prevention and treatment of new coronavirus infection (COVID-19) [Роль ренин-ангиотензин-альдостероновой системы во взаимодействии с коронавирусом SARS-CoV-2 и в развитии стратегий профилактики и лечения новой коронавирусной инфекции (COVID-19)]
No full textThe 2019 coronavirus pandemic (COVID-19), due to the new SARS-CoV-2 virus, represents the greatest global public health crisis and an unprecedented challenge to find effective ways to prevent and treat. In the active phase of a pandemic, early results allow these preventive measures to be implemented on a scale compatible with the pandemic. If the results are convincing, their value will be difficult to overestimate, since additional one or two outbreaks of this infection are expected. Clinical data is emerging rapidly from a large number of people afflicted with SARS-CoV-2, which should provide clinicians with accurate evidence of the effectiveness of different preventive and treatment methods. In particular, an active search is underway for cellular mechanisms that SARS-CoV-2 uses to penetrate tissues. These include information about the receptor of the angiotensin-converting enzyme receptor (ACE 2). SARS-CoV-2, a single-stranded envelope RNA virus, attaches to cells via a viral spike (S) protein that binds to the ACE 2. After binding to the receptor, the viral particle uses the receptors of the host cell and endosomes to enter the cells. Human type transmembrane serine protease 2 (TMPRSS 2) facilitates penetration into the cell via protein S. Once inside the cell, viral polyproteins are synthesized that encode the replicate transcriptase complex. The virus then synthesizes RNA through its RNA-dependent RNA polymerase. Structural proteins are synthesized leading to the completion of the assembly and release of viral particles. These stages of the virus life cycle provide potential targets for drug therapy. Current clinical and scientific data do not support discontinuation of ACE inhibitors or angiotensin receptor blockers in patients with COVID-19, and an ongoing discussion is addressed in this review. © 2020 All-Russian Public Organization Antihypertensive League. All rights reserved
Dry eye disease in keratoconus: etiology and medical treatment
No full text
V.V. Averich
Scientific Research Institute of Eye Diseases, Moscow, Russian Federation
This paper reviews published data on the studies on keratoconus associated with dry eye disease (DED) presentations. Despite the lack of a direct correlation between DED and keratoconus, many studies have demonstrated that keratoconus is associated with DED in more than 80% of cases. The author describes major endogenous and exogenous (inflammatory, immune/allergic, mechanical, neuropathic) factors triggering the development and association of these conditions. Approaches to the medical treatment of disorders resulting from the association of these entities are discussed. The primary management strategy implies tear film and ocular surface protection with tear substitutes based on the sodium salt of hyaluronic acid. In the lack of the effect of tear substitutes or in rigid gas permeable contact lens wearers, gel-based dexpanthenol in high concentrations is recommended. This treatment significantly increases drug bioavailability and prolongs the ocular surface reparation. Scleral contact lenses ensuring intact corneal epithelium and high visual acuity in irregular astigmatism caused by keratoconus are also used for corneal protection and DED therapy.
Keywords: keratoconus, keratectasia, dry eye disease, epitheliopathy, tear film.
For citation: Averich V.V. Dry eye disease in keratoconus: etiology and medical treatment. Russian Journal of Clinical Ophthalmology. 2022;22(2):122–126 (in Russ.). DOI: 10.32364/2311-7729-2022-22-2-122-126.
</p
The support level of V.V. Putin by the Yekaterinburg youth: the 2014 results
No full textThe article presents the data, characterizing the support level of V.V. Putin by the Yekaterinburg youth. The author shows that despite of all problems, existing in the country, Russian President has high level of political credibility and strong electoral supporting among young generation representatives. The presented data are explained.В статье представлены данные, характеризующие уровень поддержки Путина молодежью Екатеринбурга. Показано, что, несмотря на все существующие в стране проблемы, действующий Президент России пользуется высоким политическим доверием и уверенной электоральной поддержкой среди представителей молодого поколения. Приводится объяснение полученных сведений
Cartographic documents which belong to the V.V. Tarnovskyi Chernihiv historical museum by and the state fundamental material archives of Chernihiv region
No full textУ статті пропонується огляд основних картографічних
матеріалів, що зберігаються у фондах Чернігівського історичного музею ім. В.В.Тарновського та Державного архіву
Чернігівської області. Автор аналізує карти, плани, схеми
як джерело для вивчення історії регіону.This article deals with main cartographic documents which belong to
the V.V. Tarnovskyi Chernihiv historical museum by and state fundamental
material archives of Chernihiv region. The author analyzes maps,
plans, schemes as a main source to investigate the history of Chernihiv
Region
Cartographic documents which belong to the V.V. Tarnovskyi Chernihiv historical museum by and the state fundamental material archives of Chernihiv region
No full textУ статті пропонується огляд основних картографічних
матеріалів, що зберігаються у фондах Чернігівського історичного музею ім. В.В.Тарновського та Державного архіву
Чернігівської області. Автор аналізує карти, плани, схеми
як джерело для вивчення історії регіону.This article deals with main cartographic documents which belong to
the V.V. Tarnovskyi Chernihiv historical museum by and state fundamental
material archives of Chernihiv region. The author analyzes maps,
plans, schemes as a main source to investigate the history of Chernihiv
Region
- …
